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ALT-100 (HumanIgG4) is a human-derived antibody expressed in CHO cells, targeting NAMPT. It consists of a huIgG1/huIgG4 heavy chain and a huκ light chain, with an estimated molecular weight (MW) of 150 kDa. For inflammation or fibrotic diseases, the isotype control for ALT-100 (HumanIgG4) is HumanIgG4(S228P) kappa, Isotype Control. For other indications, refer to HumanIgG1kappa, Isotype Control for the isotype control of ALT-100.

Alagebrium chloride (ALT711) is an advanced glycation end product (AGE) inhibitor that has proven effective in reducing systolic blood pressure and providing therapeutic benefits for patients with diastolic.

Inbakicept is a dimer of IL-15 receptor alpha sushi domain and immunoglobulin G1 (human Fc fragment) fusion protein, which is an IL-15 super agonist protein complex. Inbakicept binds to IL-15 antibody Nogapendekin alfa to form the complex Nogapendekin alfa inbakicept (ALT-803) in a 1:2 ratio. ALT-803 has potential anticancer and anti-tumor activities, which can be used to study breast cancer.

Oregovomab is a highly specialized murine monoclonal antibody target the tumor-associated antigen CA125 (MUC16), induction of robust anti-idiotypic antibody responses and T-cell mediated anti-tumor immunity by forming immune complexes across various preclinical experimental models.

Berahyaluronidase alfa is a recombinant human hyaluronidase that temporarily increases tissue permeability by degrading hyaluronan in the extracellular matrix, thereby facilitating the absorption and dispersion of co-administered subcutaneous drugs like pembrolizumab.

ALT-007 is an orally bioavailable inhibitor of serine palmitoyltransferase (SPT), the rate-limiting enzyme in de novo ceramide synthesis. In murine models of age-related sarcopenia, ALT-007 effectively restores muscle mass and function impaired by aging. Additionally, ALT-007 may enhance protein homeostasis in Caenorhabditis elegans and in mouse models of aging and age-associated diseases, acting as a ceramide inhibitor.

ALT-946 free base is an inhibitor of advanced glycation that has been shown to improve severe nephropathy in the diabetic transgenic (mREN-2)27 rat.

ALT-946 HCl is an inhibitor of advanced glycation that has been shown to improve severe nephropathy in the diabetic transgenic (mREN-2)27 rat.

ALT-836 (TNX-832) is a humanized monoclonal antibody targeting tissue factor (TF). It binds specifically to TF and blocks the activity of the TF-FVIIa complex, thereby inhibiting the coagulation cascade and showing anti-tumor and anti-inflammatory potential.

ALT-100 (Human IgG1) is a humanized monoclonal neutralizing antibody targeting extracellular nicotinamide phosphoribosyltransferase (eNAMPT). This product binds specifically to eNAMPT, blocking its function as a damage-associated molecular pattern (DAMP) that induces pro-inflammatory and pro-fibrotic signaling. ALT-100 effectively inhibits eNAMPT-mediated TLR4 activation, reduces the release of inflammatory cytokines, and suppresses tissue remodeling. It serves as an important pharmacological tool for researching post-infarct myocardial fibrosis, acute respiratory distress syndrome (ARDS), and systemic inflammatory response syndrome.

Poly(methyl vinyl ether-alt-maleic anhydride) (MW 216000) is applicable in the preparation of antibacterial hydrogels that exhibit excellent mechanical strength and exceptional swelling capacity.

Poly(methyl vinyl ether-alt-maleic anhydride) (MW 1080000) is suitable for preparing antibacterial hydrogels that exhibit excellent mechanical strength and swelling capacity.

Methicillin sodium salt (Meticillin sodium) is a β-lactam antibiotic (natural product), a penicillin-binding protein inhibitor (anti-Staphylococcus aureus MIC=2.1 μg/mL), used for research on Staphylococcus aureus infections and inflammation-related studies.

Durlobactam sodium salt (ETX2514) is a beta-lactamase inhibitor with IC50 values of 4 nM, 14 nM and 190 nM against class A KPC-2, class C AmpC and class D OXA-24.

Dextran sulfate sodium salt (MW 36,000–50,000) is a medium molecular weight polyanionic dextran derivative with strong intestinal epithelial permeability. It is the most commonly used agent for inducing inflammatory bowel disease (IBD) models, effectively inducing both acute and chronic colitis. Its mechanism may involve macrophage dysfunction and gut microbiota dysbiosis. Due to its colonic epithelial toxicity, long-term use can also induce colorectal cancer models.

Suramin Sodium Salt (BAY-205) is a sodium salt form of suramin, a polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various growth factors, including insulin-like growth factor I (IGF-I), epidermal growth factor (EGF), platelet-derived growth factor (PDGF), and tumor growth factor-beta (TGF-beta), to their receptors, thereby inhibiting endothelial cell proliferation and migration. This agent also inhibits vascular endothelial growth factor (VEGF)- and basic fibroblast growth factor (bFGF)-induced angiogenesis; retroviral reverse transcriptase; uncoupling of G-proteins from receptors; topoisomerases; cellular folate transport; and steroidogenesis.

ATPγS tetralithium salt is a good substrate for RNA-stimulated nucleotide hydrolysis and RNA unwinding activity of eIF4A.

Nigericin sodium salt is an antibiotic, an NLRP3 activator, and a cationic ion carrier. Nigericin sodium triggers the activation of the NALP3 inflammasome, which inhibits Golgi function and suppresses the growth of Gram-positive bacteria.

Selvigaltin (GB1211) is an orally administered, highly selective small-molecule inhibitor of galectin-3 (Gal-3) with an IC₅₀ value of 12 nM in rabbits, exhibiting anticancer and anti-fibrotic activity. Selvigaltin reduces galectin-3 levels in the liver and decreases biomarkers of inflammation (cellular foci) and fibrosis (PSR, SHG), while simultaneously lowering the mRNA and protein expression of inflammatory and fibrotic biomarkers (IL-6, TGF-β3, SNAI2, collagen). Selvigaltin also restores T-cell activity and reduces tumor growth and metastasis. Selvigaltin is suitable for use in studies of liver fibrosis, non-alcoholic steatohepatitis (NASH), and tumors.

8-Bromo-cAMP sodium salt (8-Br-Camp sodium salt) is a long-acting derivative of cyclic AMP. It is an activator of cyclic AMP-dependent protein kinase（PKA）, but resistant to degradation by cyclic AMP phosphodiesterase.

NADPH tetrasodium salt is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate, which acts as an electron donor in a variety of biological reactions. NADPH tetrasodium salt is also an endogenous inhibitor of ferroptosis.

Tirzepatide sodium salt (LY3298176 sodium salt) is a GIP and GLP-1 receptor agonist with neuroprotective activity and can be used to treat obesity.

BzATP triethylammonium salt is a P2X7 receptor agonist.

CHPG sodium salt is a selective agonist of mGluR5 that activates ERK and Akt signaling pathways and is utilized in studies on traumatic brain injury.