azo

Carmoisine (Azo Rubine) is a food dye Azorubine and is used for the purposes where food is heat-treated after fermentation.

Benzoic acid, m-((p-methylaminophenyl)azo)- is a bioactive chemical.

Benzyl alcohol, m-((p-aminophenyl)azo)- is a bioactive chemical.

m-((3-Amino-4-hydroxyphenyl)azo)benzenesulphonic acid is a bioactive chemical.

m-((4-((4-(Bis(2-hydroxyethyl)amino)phenyl)azo)-1-naphthyl)azo)benzenesulphonic acid is a bioactive chemical.

m-((4-((4-Hydroxy-m-tolyl)azo)-3-methoxyphenyl)azo)benzenesulphonic acid is a bioactive chemical.

Azo-Resveratrol is an analog of Resveratrol used as a potent tyrosinase inhibitor.

Pioglitazone (U 72107) is a PPARγ agonist with EC50 of 0.93 and 0.99 μM on human and mouse PPARγ, respectively, and has selective and oral activity. Pioglitazone can be used in diabetes research.

Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity. Rosiglitazone is also a hypoglycemic agent and a thiazolidinedione insulin sensitizer.

Troglitazone (Romglizone) is a PPARγ agonist with anti-inflammatory and anti-tumor activity.

Oxazolone is a haptenating agent that can induce models of acute or chronic colitis and atopic dermatitis. It activates Th1 Th2 responses, leading to weight loss and diarrhea, and the resulting inflammation can be alleviated by anti-IL-4 antibodies, anti-TNF-α antibodies, or IL-13R2α-Fc fusion proteins. It is also suitable for studying gene expression related to inflammatory bowel disease in zebrafish.

Imidazole ketone erastin (IKE) is an ferroptosis inducer with inhibitory effects on system Xc-cystine/glutamate transporter proteins. Imidazole ketone erastin has antitumor activity and induces glutathione depletion and lipid peroxidation.

Talazoparib (LT-673) is a new-type PARP inhibitor (IC50: 0.58 nM), It similarly binds to PARP1/2 (Kis: 1.2/0.85 nM).

Dazostinag disodium (TAK-676) is a synthetic novel interferon gene (STING) agonist that triggers STING signaling pathway activation and type I interferon activation. Dazostinag disodium (TAK-676) is also a highly effective immune system modulator with complete resolution and lasting memory of T cell immunity and the ability to promote lasting interferon-dependent anti-tumor immune responses.

Azoxymethane (AOM) is a colon-specific carcinogen that induces DNA damage and forms DNA adducts, and is commonly used to establish mouse models of colorectal cancer.

6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine) is a glutaminase antagonist (Ki: 6 μM) and an antineoplastic antibiotic produced by an unidentified Streptomyces species from Peruvian soil.

Dextrorotation nimorazole phosphate ester TFA is an anti-anaerobic and anti-parasitic agent.

Levorotation nimorazole phosphate ester TFA is an anti-anaerobic and anti-parasitic agent.

Pirazolac (ZK-76604) is a novel non-steroidal anti-inflammatory agent for the study of rheumatoid arthritis.

Senazodan is a sensitiser of Ca2+, and shows inhibition effect on PDE III.

Siguazodan (SKF 94836) is an effective, selective, orally active phosphodiesterase III ((PDE-III)) inhibitor with an IC50 of 117 nM. Siguazodan inhibited phenylephrine induced 5-HT release with an IC50 value of 4.2 μM. Siguazodan can increase cAMP accumulation in intact platelets, with EC50 of 18.88 μM.

Aliconazole is an imidazole derivative with antifungal activity for the study of skin infections.

Inolitazone (RS5444) a high-affinity PPARγ agonist. Inolitazone exhibits IC50 for growth inhibition is ~0.8 nM in vitro.

Quilseconazole Formic acid is a selective inhibitor of fungal Cyp51 with potent activities against Cryptococcus neoformans and Cryptococcus gattii.