T6178 |
PTC-209 hydrobromide
|
1217022-63-3
|
98%
|
|
PTC-209 HBr is the hydrobromide salt of PTC-209, which is a potent and selective BMI-1 inhibitor with IC50 of 0.5 μM, and results in irreversible reduction of ca...
|
T14149 |
AICAR phosphate
|
681006-28-0
|
98%
|
|
AICAR phosphate (Acadesine phosphate) is an adenosine analog and a AMPK activator. AICAR phosphate regulates the glucose and lipid metabolism. It inhibits proinf...
|
T14552 |
Dactolisib Tosylate
|
1028385-32-1
|
98%
|
|
Dactolisib Tosylate (BEZ235 Tosylate) is an inhibitor of dual PI3K and mTOR kinase(IC50 values of 4, 75, 7, 5 nM for PI3Kα, β, γ, δ, respectively). Dactolisib To...
|
T0242L |
Sitagliptin phosphate monohydrate
|
654671-77-9
|
98%
|
|
Sitagliptin phosphate is a potent inhibitor of DPP-IV with IC50 of 19 nM in Caco-2 cell extracts.
|
T4123 |
LYN-1604
|
2088939-99-3
|
98%
|
|
LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.
|
TN4420 |
Latifolin
|
10154-42-4
|
98%
|
|
Latifolin is a strong DPPH-scavenger, it attenuates inflammatory responses by inhibiting NF-κB activation via Nrf2-mediated heme oxygenase-1 expression. Latifol...
|
TN2118 |
Lup-20(29)-en-28-oic acid
|
848784-85-0
|
98%
|
|
Lup-20(29)-en-28-oic acid exhibits anticancer activities in various cancer types, it Inhibits autophagic flux and synergistically enhances the anticancer activit...
|
TMA1012 |
Ganoderiol F
|
114567-47-4
|
98%
|
|
Ganoderiol F has anti-inflammatory, cytotoxic and anti-HIV activity, it inhibits activity of topoisomerases in vitro, and it inhibits human immunodeficiency viru...
|
TN4774 |
Physalin A
|
23027-91-0
|
98%
|
|
Physalin A exerts anti-tumor activity in non-small cell lung cancer cell lines by suppressing JAK/STAT3 signaling, it inhibits androgen-independent prostate canc...
|
T11372 |
GC7 Sulfate
|
150417-90-6
|
98%
|
|
GC7 Sulfate is a deoxyhypusine synthase (DHPS) inhibitor.
|
T7162 |
R1487 Hydrochloride
|
449808-64-4
|
98%
|
|
R1487 (Hydrochloride) is an orally bioavailable and highly selective inhibitors of p38α.
|
TQ0215 |
Salinomycin sodium salt
|
55721-31-8
|
98%
|
|
Salinomycin sodium salt, an antibiotic potassium ionophore, is an effective inhibitor of Wnt/β-catenin signaling.
|
TN4778 |
Physalin H
|
70241-09-7
|
98%
|
|
Physalin H is an Hh signaling inhibitor blocks GLI1-DNA-complex formation, it also strong quinone reductase induction activity with IR (Induction ratio, QR induc...
|
T32039 |
HADA Hydrochloride
|
2253733-10-5
|
98%
|
|
HADA Hydrochloride is a blue (λem~450 nm) fluorescent D-amino acid (FDAA). FDAAs are efficiently incorporated into the peptidoglycans (PGs) of diverse bacterial ...
|
T19188 |
ALLO-1
|
37468-32-9
|
98%
|
|
ALLO-1 is an autophagy receptor and is essential for autophagosome formation around paternal organelles and directly binds to the worm LC3 homologue LGG-1 throug...
|
T1606 |
Fasudil
|
103745-39-7
|
98%
|
|
Fasudil is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.
|
TN4213 |
Hirsutenone
|
41137-87-5
|
98%
|
|
Hirsutenone has potent antioxidant activity, it shows significant free radical scavenging activity and exhibits inhibition effect on the mitochondrial lipid pero...
|
TN3057 |
4-O-Methylbutein
|
13323-67-6
|
98%
|
|
4-O-Methylbutein (2',3,4'-trihydroxy-4-methoxychalcone) may have anti-inflammation activity, it is a potent heme oxygenase-1 (HO-1) inducer, the upregulation of ...
|
T15412 |
GPP78
|
1202580-59-3
|
98%
|
|
GPP78 is a potent inhibitor of Nampt (IC50: 3.0 nM for nicotinamide adenine dinucleotide (NAD) depletion). GPP78 is cytotoxic to neuroblastoma cell line SH-SY5Y ...
|
T10607 |
BRD5631
|
2446154-91-0
|
98%
|
|
BRD5631 is an autophagy enhancer, enhances autophagy through an mTOR-independent pathway. BRD5631 affects several cellular disease phenotypes previously linked t...
|