T14545 |
Berberine chloride hydrate
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68030-18-2
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98.94%
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Berberine chloride hydrate (Natural Yellow 18 chloride hydrate) is an alkaloid commonly used as an antibiotic.Berberine chloride hydrate has antitumor activity, ...
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TN3910 |
Ecdysone
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3604-87-3
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100%
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Ecdysone is a major steroid hormone in insects and herbs. Ecdysone triggers mineralocorticoid receptor activation and induces cellular apoptosis. Ecdysone signal...
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T8156 |
Saquinavir mesylate
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149845-06-7
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100%
|
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Saquinavir mesylate (Ro 31-8959/003) is an Inhibitor of HIV Proteaseused in antiretroviral therapy
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T4187 |
Gemcitabine monophosphate sodium salt hydrate
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1638288-31-9
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|
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Gemcitabine monophosphate disodium salt is a monophosphate derivative of Gemcitabine.
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T78145 |
HDAC10-IN-2 hydrochloride
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98%
|
|
HDAC10-IN-2 hydrochloride (compound 10c) is an HDAC10 inhibitor with high potency and selectivity, exhibiting an IC50 of 20 nM. It influences autophagy in aggres...
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T79371 |
HDAC-IN-62
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98%
|
|
HDAC-IN-62 (Compound 5), an HDAC inhibitor, exhibits IC50 values of 0.78, 1.0, and 1.2 μM for HDAC6, HDAC8, and HDAC11, respectively. This compound suppresses mi...
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T79556 |
NDBM
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98%
|
|
NDBM, a tumor-specific probe that targets Pim-1 kinase, exhibits heightened fluorescence upon binding and induces cytotoxicity, facilitating both cell screening ...
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T79602 |
MTP
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2377372-62-6
|
98%
|
|
MTP, a PKM2 inhibitor, promotes apoptosis in cancer cells via caspase-3 activation while also inducing autophagy and enhancing ROS generation. Further, it inhibi...
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T79653 |
VISTA-IN-2
|
2614183-36-5
|
98%
|
|
VISTA-IN-2 (Compound 1) is a V-domain Ig suppressor of T-cell activation (VISTA) inhibitor that promotes the degradation of VISTA in cells via autophagy, reverse...
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T79668 |
PIK5-12d
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98%
|
|
PIK5-12d, a potent PROTAC PIKfyve degrader (DC50: 1.48 nM), effectively induces cytoplasmic vacuolization and inhibits autophagic flux in various prostate cancer...
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T79756 |
Beclin1-ATG14L interaction inhibitor 1
|
1243063-73-1
|
98%
|
|
Beclin1-ATG14L Interaction Inhibitor 1 (COM 19) is a selective inhibitor targeting the specific interaction between Beclin1 and ATG14L. It impedes the formation ...
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T79770 |
FB49
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|
98%
|
|
FB49 is a selective Bcl-2-associated athanogene 3 (BAG3) inhibitor with a Ki of 45 μM. It inhibits the proliferation of human tumoral cells without affecting the...
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T80650 |
Di-N-desethyl amiodarone hydrochloride
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757220-04-5
|
98%
|
|
Di-N-desethyl Amiodarone hydrochloride, a metabolite of Amiodarone, functions as a potent inhibitor of the respiratory chain [1].
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T20654 |
Heparin
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9005-49-6
|
98%
|
|
Heparin (Adomiparin) is a mucopolysaccharide sulfate often used as an anticoagulant in clinical medicine.Heparin has shown partial anti-inflammatory activity in ...
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T81867 |
MAO-B-IN-26
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38470-71-2
|
98%
|
|
MAO-B-IN-26 (Compound IC9) serves as both a MAO-B and acetylcholinesterase inhibitor. It safeguards SH?SY5Y cells from Aβ-induced toxicity, including morphologic...
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T82368 |
FTO-IN-10
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|
98%
|
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FTO-IN-10 (compound 7), a potent inhibitor of the human demethylase FTO (fat mass and obesity-associated protein), exhibits an IC50 of 4.5 μM. It interacts with ...
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TQ0258 |
Corynoxine B
|
17391-18-3
|
98%
|
|
Corynoxine B is a Beclin-1-dependent autophagy inducer. It is an natural alkaloid isolated from Uncaria rhynchophylla (Miq.) Jacks (Gouteng in Chinese).
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TN4038 |
Eupatolide
|
6750-25-0
|
98%
|
|
Eupatolide is isolated from the flowers of Inula japonica with anti-inflammatory activity. Eupatolide can be used in studies about TRAIL resistance in breast can...
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TN3057 |
4-O-Methylbutein
|
13323-67-6
|
98%
|
|
4-O-Methylbutein (2',3,4'-trihydroxy-4-methoxychalcone) may have anti-inflammation activity, it is a potent heme oxygenase-1 (HO-1) inducer, the upregulation of ...
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T5143 |
Corynoxine hydrochloride(6877-32-3(free base))
|
T5143
|
98%
|
|
Corynoxine hydrochloride is a natural oxindole alkaloid and induces autophagy in different neuronal cell lines, including N2a and SHSY-5Y cells.
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