Search Result

Search Results for " phosphorylation "

652

Compounds

Natural Products

576

Recombinant Proteins

Libraries

Reagents

Cat No.	Product Name	Synonyms	Targets
T62554	PPARγ phosphorylation inhibitor 1
	PPARγ phosphorylation inhibitor 1 (Compound 10) is a potent PPARγ binding agent (IC50: 24 nM) with antidiabetic effects. PPARγ phosphorylation inhibitor 1 exhibited inhibition of CDK5-mediated PPARγ Ser273 phosphorylatio...
T76381	H1-7 (histone H1 phosphorylation site), PKA Substrate
	H1-7 (histone H1 phosphorylation site), a synthetic polypeptide serving as a PKA substrate, demonstrates utility in PKA substrate applications [1] [2].
T2431	ID-8	ID8	DYRK
	ID-8, a DYRK inhibitor, sustains embryonic stem cell self-renewal in long-term culture.		DYRK
T8574	SPHINX		Others
	SPHINX is a new generation inhibitor of SPRK1		Others
T15681	L-161982		Prostaglandin Receptor
	L-161982 is a selective antagonist of EP4 receptor. L-161982 could inhibit PGE2-induced ERK phosphorylation and cell proliferation of HCA-7 cells. L-161982 could alleviate collagen-induced arthritis in mice.		Prostaglandin Receptor
T15485	HJC0197		cAMP , Ras
	HJC0197 selectively blocks cAMP-induced Epac activation. HJC0197 is an effective exchange protein. Which straightly activated by cAMP (Epac) antagonist (IC50=5.9 μM for Epac2).		cAMP , Ras
T8423	ML417		Dopamine Receptor , Arrestin
	ML417 is a selective and brain penetrant agonist of D3 Dopamine (EC50 : 38 nM).		Dopamine Receptor , Arrestin
T15648	KDM5-C70		Histone Demethylase
	KDM5-C70 is an ethyl ester derivative of KDM5-C49. KDM5-C70 is an effective, cell-permeable, and pan-KDM5 histone demethylase inhibitor. KDM5-C70 has an antiproliferative effect in myeloma cells, inducing a genome-wide e...		Histone Demethylase
T2282	RPI-1		Others , Phospholipase , c-Met/HGFR , c-RET
	RPI-1 is a competitive, potent ATP-dependent Ret kinase inhibitor.		Others , Phospholipase , c-Met/HGFR , c-RET
T7200	TAK-960		PLK
	TAK-960 is an orally bioavailable, selective inhibitor of Plks with IC50 values of 0.8, 16.9, and 50.2 nM for Plk1, Plk2, and Plk3, respectively.		PLK
T6734	WZ8040		EGFR
	WZ8040 is a novel mutant-selective irreversible EGFRT790M inhibitor, does not inhibit ERBB2 phosphorylation (T798I).		EGFR
T16143	MRTX-1257		Ras
	MRTX-1257 is a selective, irreversible, and covalent inhibitor of KRAS G12C. It has an IC50 of 900 pM for KRAS dependent ERK phosphorylation in H358 cells. MRTX1257 demonstrated 31% bioavailability in the mouse, with fre...		Ras
T8500	VLX600		OXPHOS , Mitochondrial Metabolism , Autophagy
	VLX600 is an iron-chelating oxidative phosphorylation (OXPHOS) inhibitor, is a cell-permeable anticancer agent. It acts by reducing mitochondrial oxidative phosphorylation in tumor cells.		OXPHOS , Mitochondrial Metabolism , Autophagy
T7093	Rafoxanide		CDK , Parasite
	Rafoxanide as a dual CDK4/6 inhibitor for the treatment of skin cancer. Rafoxanide is a salicylanilide used as an anthelmintic. It is used to treat fluke, hookworm and other infestations.		CDK , Parasite
T6878	LJI308		S6 Kinase
	LJI308 is a potent, and pan-RSK (p90 ribosomal S6 kinase) inhibitor with IC50 of 6 nM, 4 nM, and 13 nM for RSK1, RSK2, and RSK3, respectively.		S6 Kinase
T9303	MRTX1133		Ras
	MRTX1133 is a KRAS G12D inhibitor (KD=0.2 pM) that is potent, selective, and non-covalent. MRTX1133 exhibits inhibitory activity against KRAS G12D-mutated tumors, but not against KRAS wild-type tumors.		Ras
TQ0111	LDN-192960		DYRK , Haspin Kinase
	LDN-192960 is a potent inhibitor of Haspin and DYRK2 (IC50s: 10 nM and 48 nM).		DYRK , Haspin Kinase
T23389	SR1664	SR 1664	PPAR
	SR1664 is a potent and selective PPARγ inhibitor with potential antidiabetic activity. SR1664 binds to PPARγ and potently inhibits Cdk5-mediated PPARγ phosphorylation (IC50 = 80 nM; Ki = 28.67 nM) without exhibiting PPAR...		PPAR
T15422	GSK-626616		DYRK
	GSK-626616 is a potent and orally bioavailable DYRK3 inhibitor (IC50: 0.7 nM). It inhibits other members of the DYRK family with similar potency. GSK-626616 is a potential therapy for the treatment of anemia.		DYRK
T2629	UNC2881		TAM Receptor
	UNC2881 is a specific Mer tyrosine kinase inhibitor (IC50: 4.3 nM). It is about 83- and 58-fold higher selectivity than Axl and Tyro3, respectively.		TAM Receptor
T7127	DC260126		Apoptosis , GPR
	DC260126 is a small-molecule antagonist of FFA1 (GPR40)		Apoptosis , GPR
T6257	AZ191		DYRK
	AZ191（IC50 of 17 nM） is an effective and specific DYRK1B inhibitor. The specificity of AZ191 for DYRK1B is about 5- and 110-fold greater over DYRK1A and DYRK2, respectively.		DYRK
T3072	XL019		Apoptosis , FLT , JAK , PDGFR
	XL019 is a potent and selective JAK2 inhibitor with IC50 of 2.2 nM, 100 fold selectivity over JAK1.		Apoptosis , FLT , JAK , PDGFR
T5092	AIM-100	AIM100	ACK
	AIM-100 is a Ack1 inhibitor (IC50: 24 nM).		ACK
T3209	AMG-337	AMG337	c-Met/HGFR
	AMG-337 is an effective and highly specific ATP-competitive MET kinase inhibitor. In enzymatic assays, AMG-337(AMG337) inhibits MET kinase activity (IC50: < 5 nM).		c-Met/HGFR
T2026	CYM5442		S1P Receptor , LPL Receptor
	CYM5442 is an S1P agonist, targeting to Sphingosine.		S1P Receptor , LPL Receptor
T9192	BIIB068		BTK
	BIIB068 is an selective, reversible and orally active BTK inhibitor (IC50 = 1 nM, Kd = 0.3 nM). BIIB068 is 400 times more selective for BTK than other kinases.		BTK
T9849	HQ461		CDK , Molecular Glues
	HQ461 is a molecular glue that promotes CDK12-DDB1 interaction to trigger cyclin K degradation, resulting in decreased CDK12 substrate phosphorylation, downregulation of DNA damage response genes, and cell death.		CDK , Molecular Glues
T2676	PF-04217903		c-Met/HGFR
	MET Tyrosine Kinase Inhibitor PF-04217903 is an orally bioavailabe, small-molecule tyrosine kinase inhibitor with potential antineoplastic activity.		c-Met/HGFR
T5674	H-151		STING
	H-151 is a highly potent and selective STING antagonist. H-151 covalently binds to Cys91 of STING and inhibits palmitoylation of Cys91, thereby inhibiting STING activity. H-151 can be used in the study of autoinflammator...		STING
T13018	SU3327	halicin	JNK
	SU3327 (halicin) is a potent, selective and substrate-competitive inhibitor of JNK(IC50 of 0.7 μM).		JNK
T6207	SC144		Apoptosis , Interleukin
	SC144 is an orally active small-molecule gp130 inhibitor.		Apoptosis , Interleukin
T20533	NNK	Nicotine-derived nitrosamine ketone	Lipoxygenase
	NNK (Nicotine-derived nitrosamine ketone) is a procarcinogen and a major tobacco-specific toxicant. It inhibits the expression of lysyl oxidase which is a tumor suppressor.		Lipoxygenase
T12871	Talmapimod	SCIO-469	p38 MAPK
	Talmapimod (SCIO-469) is an selective, orally active, and ATP-competitive p38α inhibitor with IC50 of 9 nM and 90 nM for p38α and p38β, respectively. Talmapimod exhibits at least 2000-fold selectivity over a panel of 20 ...		p38 MAPK
T8684	Sotorasib	AMG-510	Ras
	Sotorasib (AMG-510) is an orally active and selective covalent inhibitor of KRAS G12C. Sotorasib binds to the GDP state of the inactive conformation of KRAS G12C and inhibits KRAS and its downstream signaling. Sotorasib ...		Ras
T22461	YKL-5-124		CDK
	YKL-5-124, a potent, selective and covalent CDK7 inhibitor with an IC50 of 9.7 nM, 1300 nM and 3020 nM for CDK7/Mat1/CycH, CDK2 and CDK9 respectively, displays biochemical and cellular selectivity for CDK7 over CDK12/13...		CDK
T6761	Ossirene	AS101	IL Receptor , Caspase , Interleukin
	Ossirene (AS101), a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.		IL Receptor , Caspase , Interleukin
T1921	Alpelisib	BYL-719	PI3K
	Alpelisib (BYL-719) is a PI3Kα inhibitor (IC50=5 nM) with selective, potent, and oral activity. Alpelisib inhibits PI3Kβ/γ/δ with low activity (IC50=250/290/1200 nM). Alpelisib has antitumor activity and is targeted to P...		PI3K
T13099	TC ASK 10		ASK , MAPK
	TC ASK 10 is a potent, selective and orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1)(IC50 of 14 nM).		ASK , MAPK
T11279	FGFR1/DDR2 inhibitor 1		Discoidin Domain Receptor (DDR) , FGFR , Others
	FGFR1/DDR2 inhibitor 1 is an inhibitor of discoindin domain receptor 2 (DDR2) and fibroblast growth factor receptor 1 (FGFR1), with IC50 values of 31.1 nM, 108.4 nM and 3.2 nM for FGFR1, KG-1, and DDR2, respectively.		Discoidin Domain Receptor (DDR) , FGFR , Others
T5125	LY3200882		TGF-beta/Smad
	LY3200882 is a highly selective inhibitor of TGF-β receptor type 1 (TGFβRI).		TGF-beta/Smad
T6303	CCT128930		Akt , PKA , S6 Kinase , Autophagy
	CCT128930 is a potent, ATP-competitive and selective inhibitor of Akt2 with IC50 of 6 nM, 28-fold greater selectivity for Akt2 than the closely related PKA kinase.		Akt , PKA , S6 Kinase , Autophagy
T11447	GNF4877		GSK-3 , DYRK
	GNF4877 is a potent DYRK1A and GSK3β inhibitor (IC50s: 6 nM and 16 nM). It leads to blockade of nuclear factor of activated T-cells (NFATc) nuclear export and increased β-cell proliferation cells.		GSK-3 , DYRK
T22012	7BIO		FLT , DYRK , Aurora Kinase
	7-bromoindirubin-3'-oxime (7BIO) is a caspase independent nonapoptotic cell death inducer. 7BIO is an inhibitor of FLT3, DYRK1A, DYRK2, Aurora B and Aurora C kinases.		FLT , DYRK , Aurora Kinase
T9356	(E/Z)-GO289		Casein Kinase
	(E/Z)-GO289, which strongly lengthened circadian period, is a potent and selective inhibitor of CK2. (E/Z)-GO289 exhibited cell type-dependent inhibition of cancer cell growth that correlated with cellular clock function...		Casein Kinase
T12148	N-Desmethyltamoxifen hydrochloride		Estrogen Receptor/ERR , Endogenous Metabolite , PKC
	N-Desmethyltamoxifen hydrochloride is the major tamoxifen metabolite in humans.		Estrogen Receptor/ERR , Endogenous Metabolite , PKC
T2680	NVP-BVU972		c-Met/HGFR
	NVP-BVU972 is a selective and potent Met inhibitor with IC50 of 14 nM.		c-Met/HGFR
T9211	Mito-LND	Mito-Loidamine	OXPHOS , Reactive Oxygen Species , Mitochondrial Metabolism , Autophagy
	Mito-LND (Mito-Loidamine) is an orally active and mitochondria-targeted inhibitor of oxidative phosphorylation.
T8492	BO-264		Apoptosis , FGFR
	BO-264 is a highly potent and orally active inhibitor of transforming acidic coiled-coil 3 (TACC3, IC50 of 188 nM and a Kd of 1.5 nM).		Apoptosis , FGFR
T3185	R112	(E)-Elafibranor	Syk
	R112 ((E)-Elafibranor) is an ATP-competitive inhibitor of Syk kinase.		Syk

Compounds

PPARγ phosphorylation inhibitor 1

T62554

Synonym:

Target:

H1-7 (histone H1 phosphorylation site), PKA Substrate

Target: Prostaglandin Receptor

Target: Dopamine Receptor, Arrestin

KDM5-C70

T15648

Synonym:

Target: Histone Demethylase

RPI-1

T2282

Synonym:

Target: Others, Phospholipase, c-Met/HGFR, c-RET

Target: OXPHOS, Mitochondrial Metabolism, Autophagy

Rafoxanide

T7093

Synonym:

Target: CDK, Parasite

Target: DYRK, Haspin Kinase

Target: Apoptosis, GPR

Target: Apoptosis, FLT, JAK, PDGFR

Target: S1P Receptor, LPL Receptor

Target: CDK, Molecular Glues

Target: Apoptosis, Interleukin

NNK

T20533

Synonym: Nicotine-derived nitrosamine ketone

Target: IL Receptor, Caspase, Interleukin

FGFR1/DDR2 inhibitor 1

T11279

Synonym:

Target: Discoidin Domain Receptor (DDR), FGFR, Others

LY3200882

T5125

Synonym:

Target: TGF-beta/Smad

CCT128930

T6303

Synonym:

Target: Akt, PKA, S6 Kinase, Autophagy

Target: FLT, DYRK, Aurora Kinase

(E/Z)-GO289

T9356

Synonym:

Target: Casein Kinase

N-Desmethyltamoxifen hydrochloride

T12148

Synonym:

Target: Estrogen Receptor/ERR, Endogenous Metabolite, PKC

Synonym: Mito-Loidamine

Target: OXPHOS, Reactive Oxygen Species, Mitochondrial Metabolism, Autophagy

BO-264

T8492

Synonym:

Target: Apoptosis, FGFR

R112

T3185

Synonym: (E)-Elafibranor

Target: Syk

Cat No.	Product Name	Synonyms	Targets
TN6739	Angoline	6-Methoxyldihydrochelerythrine	IL Receptor , STAT
	Angoline (6-Methoxyldihydrochelerythrine) hydrochloride is a potent and selective IL6/STAT3 signaling pathway inhibitor(IC50 : 11.56 μM). It inhibits STAT3 phosphorylation and its target gene expression, and inhibits can...		IL Receptor , STAT
TN1118	Tormentic acid		Immunology/Inflammation related
	Tormentic acid is a natural product. It has anticancer, anti-inflammatory, anti-atherogenic , anti-allodynic, and hepatoprotective properties,		Immunology/Inflammation related
T1711	Harmine	Telepathine	MAO , 5-HT Receptor , DYRK
	Harmine (Telepathine) is an alkaloid isolated from seeds of Peganum harmala.		MAO , 5-HT Receptor , DYRK
T0683	Mevastatin	Compactin,ML236B	Apoptosis , Antibacterial , Antibiotic , HMG-CoA Reductase , Autophagy , Lipid
	Mevastatin (ML236B) is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium ultimum. Mevastatin was the first statin to enter clinical trials.
T0760	Cholesterol	Cholesterin,Cholesteryl alcohol	Estrogen Receptor/ERR , MRP , Endogenous Metabolite , ROR
	Cholesterol (cholesteryl alcohol) is a natural product that is the major sterol in mammals and an agonist of estrogen-related receptor α (ERRα). Cholesterol is widely found in the cell membranes of animals and is also us...		Estrogen Receptor/ERR , MRP , Endogenous Metabolite , ROR
T4592	TOMATIDINE HYDROCHLORIDE	Tomatidine,Tomatidine HCl	Others , NF-κB , JNK , Autophagy
	Tomatidine hydrochloride (Tomatidine HCl) is a steriodal alkaloid structurally similar to Cyclopamine but does not inhibit hedgehog pathway. May be used as a negative control for Cyclopamine and KAAD-Cyclopamine. Tomatid...		Others , NF-κB , JNK , Autophagy
T2811	Harmine hydrochloride	telepathine hydrochloride	5-HT Receptor , DYRK , GluR
	Harmine hydrochloride (telepathine hydrochloride) is extracted from Peganum Harmala Genus.		5-HT Receptor , DYRK , GluR
T8160	EGCG Octaacetate		Others , Antibacterial
	EGCG Octaacetate, a prodrug of EGCG, is utilized to enhance the stability and bioavailability of EGCG in vivo. It has high efficacy, bioavailability, anti-oxidation, and anti-angiogenesis capacities.		Others , Antibacterial
T7917	4'-Hydroxychalcone	2-Benzal-4-Hydroxyacetophenone	Proteasome
	4'-Hydroxychalcone (2-Benzal-4-Hydroxyacetophenone) is a chalcone metabolite with hepatoprotective activity		Proteasome
T1181	Gefitinib	ZD1839	EGFR , Tyrosine Kinases , Autophagy
	Gefitinib (ZD1839) is an EGFR first-generation inhibitor with oral activity that inhibits the EGFR 19 Del and L858R mutations. Gefitinib has antitumor activity and is used for the treatment of EGFR-mutated non-small-cell...		EGFR , Tyrosine Kinases , Autophagy
T17143	Toyocamycin	Vengicide	Apoptosis , Others , IRE1 , Antibiotic , Antifungal
	Toyocamycin (Vengicide) is an adenosine analog produced by Actinomycete, acts as an XBP1 inhibitor, inhibits IRE1α-induced ATP-dependent XBP1 mRNA cleavage (IC50: 80 nM). Toyocamycin induces apoptosis.		Apoptosis , Others , IRE1 , Antibiotic , Antifungal
TN2019	Orobol	3'-Hydroxygenistein,3’,4’,5,7-tetrahydroxy-isoflavon	BCL , Caspase , PI3K
	Orobol (3’,4’,5,7-tetrahydroxy-isoflavon) is an inhibitor of tyrosine-specific protein kinase and phosphatidylinositol turnover. Orobol inhibits PI3K isoforms with IC50s of 3.46-5.27 μM for PI3K α/β/γ/K/δ. Orobol exhibit...		BCL , Caspase , PI3K
T10662L	Calcimycin	Antibiotic A-23187,A-23187	Apoptosis , Antibacterial , Antibiotic , Autophagy , Antifungal
	Calcimycin (A-23187) is an ionophorous, polyether carboxylic antibiotic from Streptomyces chartreusensis. It binds and transports calcium and other divalent cations across membranes and uncouples oxidative phosphorylatio...
T2755	Rhoifolin	Apigenin-7-O-rhamnoglucoside,Apigenin 7-O-neohesperidoside,Rhoifoloside	Others , p38 MAPK , NF-κB , transporter , IGF-1R , Autophagy
	Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves.
TN1013	Cucurbitacin D		IL Receptor , JNK , STAT
	Cucurbitacin D has anticancer effects, it induces apoptosis through caspase-3 and phosphorylation of JNK in hepatocellular carcinoma cells.		IL Receptor , JNK , STAT
T3755	Pinostilbene		Others
	Pinostilbene obviously attenuates the phosphorylation of c-Jun and JNK triggered by 6-OHDA.		Others
TQ0184	Chebulinic acid		ATPase , Proton pump , DNA/RNA Synthesis , Antibacterial , TGF-beta/Smad
	Chebulinic acid is a potent inhibitor of M. tuberculosis DNA gyrase. It also can inhibit SMAD-3 phosphorylation and H+ K+-ATPase activity.
T13265	Urolithin B		ERK , NF-κB , Akt , Endogenous Metabolite , JNK , AMPK
	Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in diverse plant foods, including pomegranates, berries, walnuts, tropical fruits, and medicinal herbs. Urolithin B inhibits NF-κB activit...		ERK , NF-κB , Akt , Endogenous Metabolite , JNK , AMPK
T4S0498	Glaucocalyxin A	Wangzaozin B,Leukamenin F	Apoptosis , Akt , Caspase , PI3K
	1. Glaucocalyxin A (Leukamenin F)-SBE-β-CD could be useful with a better solubility and sustained function in drug delivery. 2. Glaucocalyxin A activates caspase-3, decreases BAD phosphorylation, and reduces the expressi...		Apoptosis , Akt , Caspase , PI3K
T3399	Psoralidin		Others , Estrogen/progestogen Receptor , Reactive Oxygen Species , Lipoxygenase , Gamma-secretase , Akt , COX , Antibacterial
	Psoralidin inhibits Akt phosphorylation and phosphatidylinositol 3-kinase activation and transcriptionally. Psoralidin possesses anticancer and chemopreventive properties.
T5668	Triacetylresveratrol	Acetyl-trans-resveratrol	BCL , NF-κB , STAT
	Triacetylresveratrol (Acetyl-trans-resveratrol) has anti-cancer activity,it inhibits the phosphorylation of STAT3 and NFκB, down-regulates Mcl-1, and up-regulates Bim and Puma in pancreatic cancer cells.		BCL , NF-κB , STAT
T4S0295	Apigenin 7-glucoside	Cosmetin,Cosmosiin,Cosmosioside,Apigenin-7-O-β-D-glucopyranoside,Thalictiin,Apigetrin	Reactive Oxygen Species , HIV Protease
	1. Apigenin 7-glucoside (Cosmosiin) is a anti-HIV agent. 2. Cosmosiin may be beneficial for diabetic complications through their enhanced adiponectin secretion, tyrosine phosphorylation of insulin receptor-β and GLUT4 tr...		Reactive Oxygen Species , HIV Protease
T2731	Usnic Acid	Usniacin	Antibacterial , Autophagy
	Usnic Acid (Usniacin) is an antimicrobial, antitumor and enzyme inhibiting agent shown to uncouple oxidative phosphorylation in mouse-liver mitochondria. Usnic acid induces necrosis in certain cells.		Antibacterial , Autophagy
T67708	Thiolutin	Acetopyrrothin	Antibacterial , Antibiotic
	Thiolutin (Acetopyrrothin) is an inhibitor of endothelial cell adhesion and produced by Streptomyces. Thiolutin shows antibiotic and anti-angiogenic properties. Thiolutin induces the phosphorylation of Hsp27 rapidly.		Antibacterial , Antibiotic
T3384	Wedelolactone	IKK Inhibitor II	Apoptosis , NF-κB , Lipoxygenase , Caspase
	Wedelolactone (IKK Inhibitor II) inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα.		Apoptosis , NF-κB , Lipoxygenase , Caspase
T2814	Cryptotanshinone	Cryptotanshinon,Tanshinone c	STAT , Autophagy
	Cryptotanshinone (Cryptotanshinon), a STAT3 inhibitor (IC50: 4.6 μM) in a cell-free assay, strongly inhibits phosphorylation of STAT3 Tyr705, with a little effect on STAT3 Ser727, but no inhibition for STAT1 nor STAT5.		STAT , Autophagy
T6323	Oligomycin A	MCH 32	ATPase , Antibiotic , Antifungal
	Oligomycin A (MCH 32) is an inhibitor of ATP synthase, inhibits oxidative phosphorylation and all the ATP-dependent processes occurring on the coupling membrane of mitochondria.		ATPase , Antibiotic , Antifungal
T3001	Honokiol	NSC 293100	ERK , HCV Protease , MEK , Akt , Autophagy
	Honokiol (NSC-293100) is the active principle of magnolia extract. It inhibits the activation of Akt and enhances the phosphorylation of ERK1/ERK2.		ERK , HCV Protease , MEK , Akt , Autophagy
T0906	Salinomycin	Procoxacin	Wnt/beta-catenin , Antibacterial
	Salinomycin (Procoxacin), a polyether potassium ionophore antibiotic, specifically inhibits the growth of gram-positive bacteria. It acts as a potent inhibitor of Wnt/β-catenin signaling, blocking Wnt-induced LRP6 phosph...		Wnt/beta-catenin , Antibacterial
T2S1975	Ponicidin	Rubescensine B	Apoptosis , JAK , STAT
	Ponicidin (Rubescensine B) is a diterpenoid derived from Rabdosia rubescens. Ponicidin exhibits immunoregulatory, anti-inflammatory, anti-viral, and anti-cancer activity. Ponicidin induces apoptosis of gastric carcinoma ...		Apoptosis , JAK , STAT
T19262	D-Glucose 6-phosphate disodium salt	D-Glucose 6-phosphate disodium salt	Endogenous Metabolite
	D-Glucose 6-phosphate disodium salt is a compound widely present in biological systems. It is a molecule formed when glucose undergoes phosphorylation at the 6th carbon. This compound participates in various metabolic re...		Endogenous Metabolite
T3S1775	Tectochrysin	NSC 80687,Techtochrysine,Techtochrysin	NF-κB , STAT
	1. Tectochrysin (Techtochrysine) has antioxidant effect. 2. Tectochrysin is promising inhibitors for the reversal of ABCG2-mediated drug transport. 3. Tectochrysin leads to apoptotic cell death in NSC-LC cells through ac...		NF-κB , STAT
T3908	10-Gingerol		Apoptosis
	10-Gingerol-induced apoptosis was accompanied by phosphorylation of the mitogen-activated protein kinase (MAPKs) family, p38 MAPK (p38), c-Jun N-terminal kinase (JNK), and extracellular signal-regulated kinase (ERK).		Apoptosis
TP1072	Valinomycin	NSC 122023	Apoptosis , PTEN , Antibacterial , Antibiotic , Autophagy
	Valinomycin (NSC-122023) is a cyclic depsipeptide antibiotic and a potassium-specific ionophore.Valinomycin induces PINK1 activation and promotes Parkin phosphorylation at Ser65.		Apoptosis , PTEN , Antibacterial , Antibiotic , Autophagy
T3S0156	Atractyloside potassium salt	Atractyloside Dipotassium Salt	Others
	1. Atractyloside potassium salt (Atractyloside Dipotassium Salt) inhibits oxidative phosphorylation by blocking the transfer of adenosine nucleotides through the mitochondrial membrane.		Others
T3391	Corosolic acid	Corsolic acid,2α-Hydroxyursolic acid,Glucosol,Colosolic acid,Colosic acid	FAK , Autophagy
	Corosolic acid (Colosic acid) contains anti-angiogenic activity that can suppress FAK signaling induced by angiopoietin-1. Corosolic acid exerts anticancer activities against HCC, colon, and colorectal Y cells, by induci...		FAK , Autophagy
T3816	Velutin		NF-κB , HIF/HIF Prolyl-Hydroxylase
	Velutin shows the strongest inhibitory effect in NF-κB activation and exhibits the greatest effects in blocking the degradation of inhibitor of NF-κB as well as in inhibiting mitogen-activated protein kinase p38 and JNK ...		NF-κB , HIF/HIF Prolyl-Hydroxylase
T4731	2'-Deoxycytidine-5'-monophosphoric acid	dCMP,2'-Deoxycytidine 5'-monophosphate	Others , Endogenous Metabolite
	2'-Deoxycytidine-5'-monophosphoric acid (2'-Deoxycytidine 5'-monophosphate) is used as a substrate of uridine monophosphate (UMP)/cytidine monophosphate (CMP) kinase (EC 2.7.4.4) to form dCDP which upon phosphorylation t...		Others , Endogenous Metabolite
T21494	Oligomycin		HIF
	Oligomycin is an antifungal antibiotic that is an inhibitor of H+-ATP synthetase. The Oligomycin blocks oxidative phosphorylation and the electron transport chain. Oligomycin inhibited HIF-1alpha expression in hypoxic tu...		HIF
TN1103	Diphyllin		ATPase , Proton pump , Influenza Virus , HIV Protease
	Diphyllin could be characterized as a new V-ATPase inhibitor in treating gastric cancer and inhibiting the phosphorylation of LRP6 in Wnt/β-catenin signaling.		ATPase , Proton pump , Influenza Virus , HIV Protease
TN2269	Tetramethylcurcumin		Apoptosis , STAT
	Tetramethylcurcumin is a novel curcumin analog, is an effective inhibitors of STAT3 phosphorylation, DNA binding activity, and transactivation in vitro.it also inhibits colony formation in soft agar, cell invasion, and e...		Apoptosis , STAT
T4237	Rubiadin-1-methyl ether	Rubiadin 1-methyl ether	Anti-infection , NF-κB
	Rubiadin-1-methyl ether (Rubiadin 1-methyl ether) is a natural product.It inhibits osteoclastic bone resorption via inhibition on the phosphorylation of NF-κB p65 and the degradation of IκBα as well as decrease in the nu...		Anti-infection , NF-κB
T6S1543	Dehydrodiisoeugenol		Others , NF-κB , COX , Antibacterial
	1. Dehydrodiisoeugenol has anti-inflammatory activity. (1). Dehydrodiisoeugenol inhibited the expression of the COX-2 in RAW264.7 murine macrophages stimulated with LPS. (2). Dehydrodiisoeugenol inhibited LPS-stimulated ...		Others , NF-κB , COX , Antibacterial
T4S2128	Bilobetin		PKA , PPAR
	Bilobetin ameliorates insulin resistance by PKA-mediated phosphorylation of PPARα in rats fed a high-fat diet.		PKA , PPAR
TN1637	Eurycomalactone		Anti-infection , NF-κB
	Eurycomalactone is a natural product isolated from Eurycoma longifolia Jack., acts as a potent NF-κB inhibitor( IC50 of 0.5 μM). Eurycomalactone inhibits protein synthesis, depletes cyclin D1, but does not affect TNFα-in...		Anti-infection , NF-κB
T5S1331	Herbacetin		c-Met/HGFR , Akt
	1. Herbacetin induces apoptosis in HepG2 cells, by ROS and PI3K/Akt pathway. 2. Herbacetin suppresses the HGF-induced motility of human breast cancer MDA-MB-231 cells by inhibiting c-Met and Akt phosphorylation.		c-Met/HGFR , Akt
T5S0890	Oleandrin	Neriostene,Folinerin,Foliandrin	Apoptosis , ATPase , Potassium Channel , Sodium Channel
	1. Oleandrin (Folinerin), the principal cardiac glycoside component of PBI-524, can quantitatively account for regulation of BDNF at both the protein and transcriptional levels. 2. Oleandrin are known to inhibit the Na, ...		Apoptosis , ATPase , Potassium Channel , Sodium Channel
T1020	Doxorubicin hydrochloride	Adriamycin,Doxorubicin (Adriamycin) HCl,Hydroxydaunorubicin hydrochloride,NSC 123127	Apoptosis , Mitophagy , HBV , HIV Protease , Topoisomerase , Antibacterial , Antibiotic , AMPK , Autophagy
	Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM). Doxorubicin hydrochloride exhibits cytotoxicity and antitum...
T32614	L-Clausenamide	(-)-Clausenamide	Microtubule Associated
	L-Clausenamide is an alkaloid extracted from the leaves of the yellow bark (Clausena lansium (Lour) skeels) and can be used to improve cognitive function. L-Clausenamide inhibits beta-amyloid (Aβ) toxicity and prevents t...		Microtubule Associated
T5079	Adenosine 5'-diphosphate sodium salt	Adenosine-5'-diphosphate trisodium salt,ADP sodium salt	Others , Endogenous Metabolite
	Adenosine 5'-diphosphate sodium salt (ADP sodium salt) is an adenine nucleotide that is phosphorylated into ATP by ATPase. This phosphorylation is a key part of cellular homeostatis as it allows for energy storage and is...		Others , Endogenous Metabolite
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Natural Products

Angoline

TN6739

Synonym: 6-Methoxyldihydrochelerythrine

Target: IL Receptor, STAT

Tormentic acid

TN1118

Synonym:

Target: Immunology/Inflammation related

Harmine

T1711

Synonym: Telepathine

Target: MAO, 5-HT Receptor, DYRK

Mevastatin

T0683

Synonym: Compactin,ML236B

Target: Apoptosis, Antibacterial, Antibiotic, HMG-CoA Reductase, Autophagy, Lipid

Cholesterol

T0760

Synonym: Cholesterin,Cholesteryl alcohol

Target: Estrogen Receptor/ERR, MRP, Endogenous Metabolite, ROR

TOMATIDINE HYDROCHLORIDE

T4592

Synonym: Tomatidine,Tomatidine HCl

Target: Others, NF-κB, JNK, Autophagy

Harmine hydrochloride

T2811

Synonym: telepathine hydrochloride

Target: 5-HT Receptor, DYRK, GluR

EGCG Octaacetate

T8160

Synonym:

Target: Others, Antibacterial

4'-Hydroxychalcone

T7917

Synonym: 2-Benzal-4-Hydroxyacetophenone

Target: EGFR, Tyrosine Kinases, Autophagy

Toyocamycin

T17143

Synonym: Vengicide

Target: Apoptosis, Others, IRE1, Antibiotic, Antifungal

Orobol

TN2019

Synonym: 3'-Hydroxygenistein,3’,4’,5,7-tetrahydroxy-isoflavon

Target: BCL, Caspase, PI3K

Calcimycin

T10662L

Synonym: Antibiotic A-23187,A-23187

Target: Apoptosis, Antibacterial, Antibiotic, Autophagy, Antifungal

Rhoifolin

T2755

Synonym: Apigenin-7-O-rhamnoglucoside,Apigenin 7-O-neohesperidoside,Rhoifoloside

Target: Others, p38 MAPK, NF-κB, transporter, IGF-1R, Autophagy

Cucurbitacin D

TN1013

Synonym:

Target: IL Receptor, JNK, STAT

Target: ATPase, Proton pump, DNA/RNA Synthesis, Antibacterial, TGF-beta/Smad

Urolithin B

T13265

Synonym:

Target: ERK, NF-κB, Akt, Endogenous Metabolite, JNK, AMPK

Glaucocalyxin A

T4S0498

Synonym: Wangzaozin B,Leukamenin F

Target: Apoptosis, Akt, Caspase, PI3K

Psoralidin

T3399

Synonym:

Target: Others, Estrogen/progestogen Receptor, Reactive Oxygen Species, Lipoxygenase, Gamma-secretase, Akt, COX, Antibacterial

Triacetylresveratrol

T5668

Synonym: Acetyl-trans-resveratrol

Target: BCL, NF-κB, STAT

Apigenin 7-glucoside

T4S0295

Synonym: Cosmetin,Cosmosiin,Cosmosioside,Apigenin-7-O-β-D-glucopyranoside,Thalictiin,Apigetrin

Target: Reactive Oxygen Species, HIV Protease

Usnic Acid

T2731

Synonym: Usniacin

Target: Antibacterial, Autophagy

Thiolutin

T67708

Synonym: Acetopyrrothin

Target: Antibacterial, Antibiotic

Wedelolactone

T3384

Synonym: IKK Inhibitor II

Target: Apoptosis, NF-κB, Lipoxygenase, Caspase

Cryptotanshinone

T2814

Synonym: Cryptotanshinon,Tanshinone c

Target: STAT, Autophagy

Oligomycin A

T6323

Synonym: MCH 32

Target: ATPase, Antibiotic, Antifungal

Honokiol

T3001

Synonym: NSC 293100

Target: ERK, HCV Protease, MEK, Akt, Autophagy

Salinomycin

T0906

Synonym: Procoxacin

Target: Wnt/beta-catenin, Antibacterial

Ponicidin

T2S1975

Synonym: Rubescensine B

Target: Apoptosis, JAK, STAT

D-Glucose 6-phosphate disodium salt

T19262

Synonym: D-Glucose 6-phosphate disodium salt

Target: Endogenous Metabolite

Tectochrysin

T3S1775

Synonym: NSC 80687,Techtochrysine,Techtochrysin

Target: Apoptosis, PTEN, Antibacterial, Antibiotic, Autophagy

Atractyloside potassium salt

T3S0156

Synonym: Atractyloside Dipotassium Salt

Target: Others

Corosolic acid

T3391

Synonym: Corsolic acid,2α-Hydroxyursolic acid,Glucosol,Colosolic acid,Colosic acid

Target: FAK, Autophagy

Velutin

T3816

Synonym:

Target: NF-κB, HIF/HIF Prolyl-Hydroxylase

2'-Deoxycytidine-5'-monophosphoric acid

T4731

Synonym: dCMP,2'-Deoxycytidine 5'-monophosphate

Target: Others, Endogenous Metabolite

Target: ATPase, Proton pump, Influenza Virus, HIV Protease

Tetramethylcurcumin

TN2269

Synonym:

Target: Apoptosis, STAT

Rubiadin-1-methyl ether

T4237

Synonym: Rubiadin 1-methyl ether

Target: Anti-infection, NF-κB

Dehydrodiisoeugenol

T6S1543

Synonym:

Target: Others, NF-κB, COX, Antibacterial

Target: Anti-infection, NF-κB

Herbacetin

T5S1331

Synonym:

Target: c-Met/HGFR, Akt

Oleandrin

T5S0890

Synonym: Neriostene,Folinerin,Foliandrin

Target: Apoptosis, ATPase, Potassium Channel, Sodium Channel

Doxorubicin hydrochloride

T1020

Synonym: Adriamycin,Doxorubicin (Adriamycin) HCl,Hydroxydaunorubicin hydrochloride,NSC 123127

Target: Apoptosis, Mitophagy, HBV, HIV Protease, Topoisomerase, Antibacterial, Antibiotic, AMPK, Autophagy

L-Clausenamide

T32614

Synonym: (-)-Clausenamide

Target: Microtubule Associated

Adenosine 5'-diphosphate sodium salt

T5079

Synonym: Adenosine-5'-diphosphate trisodium salt,ADP sodium salt

Target: Others, Endogenous Metabolite

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Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-04380	DYRK3 Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	Dual specificity tyrosine-phosphorylation-regulated kinase 3, also known as Regulatory erythroid kinase, REDK and DYRK3, is a nucleus protein which belongs to theprotein kinase superfamily, CMGC Ser/Thr protein kinase...
TMPY-03024	HER3/ERBB3 Protein, Rat, Recombinant (His)	Rat	HEK293
	ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin...
TMPY-04956	HER3/ERBB3 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
	ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin...
TMPY-01389	HER3/ERBB3 Protein, Human, Recombinant (His)	Human	HEK293
	ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin...
TMPY-00246	HER3/ERBB3 Protein, Rhesus, Recombinant	Rhesus	HEK293
	ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin...
TMPY-00399	HER3/ERBB3 Protein, Human, Recombinant	Human	HEK293
	ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin...
TMPY-02477	HER3/ERBB3 Protein, Rhesus, Recombinant (His)	Rhesus	HEK293
	ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin...
TMPY-02365	HER3/ERBB3 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin...
TMPY-00586	CLEC-2 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	CLEC1B, also known as CLEC2, is a C-type lectin-like receptor expressed in myeloid cells and NK cells. Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 and NKG2D, ...
TMPY-01053	Prolactin Receptor Protein, Human, Recombinant (His)	Human	HEK293
	Prolactin receptor (PRLR) is a single-pass transmembrane receptor belonging to the type I cytokine receptor superfamily, and contains two fibronectin type-III domains. All class 1 ligands activate their respective recept...
TMPK-00785	ANXA2 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	ANXA2, highly expressed in invasive breast cancer cells, is closely related with poor prognosis, and acts as a molecular switch to EGFR activation. ANXA2 expression is inversely correlated with cell sensitivity to gefiti...
TMPY-01085	VLDLR Protein, Human, Recombinant (His)	Human	HEK293
	The very low density lipoprotein receptor, known as VLDLR, is a single-pass type 1 integral membrance protein and a member of the LDL receptor family. This receptor family includes LDL receptor, LRP, megalin, VLDLR and A...
TMPJ-00113	CD79B Protein, Human, Recombinant (hFc)	Human	Human Cells
	CD79B is a single-pass type I membrane protein. CD79B contains one Ig-like V-type domain and one ITAM domain. CD79B is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the...
TMPH-00009	OGT Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Catalyzes the transfer of a single N-acetylglucosamine from UDP-GlcNAc to a serine or threonine residue in cytoplasmic and nuclear proteins resulting in their modification with a beta-linked N-acetylglucosamine (O-GlcNAc...
TMPY-04548	CDK4 Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	CDK4 is a member of the Ser/Thr protein kinase family. It is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cel...
TMPY-04356	GSK3B Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	GSK3B is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It Contains 1 protein kinase domain, and is expressed in the testis, thymus, prostate, and ovary and weakly expressed in the lung, ...
TMPJ-00166	SCF Protein, Mouse, Recombinant	Mouse	E. coli
	Mouse stem cell factor (SCF), is the ligand for the receptor-type protein-tyrosine kinase KIT. It plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gameto...
TMPY-05338	IL-10R alpha/IL-10RA Protein, Human, Recombinant (His)	Human	HEK293
	IL10RA (Interleukin 10 Receptor Subunit Alpha, also known as CD210) is a Protein Coding gene. The protein encoded by this gene is a receptor for interleukin 10. Two transcript variants, one protein-coding, and the other,...
TMPY-05496	IL-10R alpha/IL-10RA Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	IL10RA (Interleukin 10 Receptor Subunit Alpha, also known as CD210) is a Protein Coding gene. The protein encoded by this gene is a receptor for interleukin 10. Two transcript variants, one protein-coding, and the other,...
TMPY-04384	Src Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	Proto-oncogene tyrosine-protein kinase SRC is a hydrophobic protein belonging to the SRC family kinase including nine members that is a family of non-receptor tyrosine kinases. SRC protein may exist in different forms: C...
TMPY-02647	IFNAR1 Protein, Human, Recombinant (His)	Human	HEK293
	Interferon-alpha/beta receptor alpha chain (IFNAR1) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulate Janus prote...
TMPY-04083	Siglec-2/CD22 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. CD22 serves as an adhesi...
TMPY-05566	Siglec-2/CD22 Protein, Human, Recombinant (His, Solution)	Human	HEK293
	CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. CD22 serves as an adhesi...
TMPY-05201	Siglec-2/CD22 Protein, Human, Recombinant	Human	HEK293
	CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. CD22 serves as an adhesi...
TMPY-02034	Siglec-2/CD22 Protein, Human, Recombinant (His)	Human	HEK293
	CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. CD22 serves as an adhesi...
TMPY-02603	STAT6 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Signal transducer and activator of transcription 6 (STAT6) is a transcription factor that is activated by interleukin-4 (IL-4)-induced tyrosine phosphorylation and mediates most of the IL-4-induced gene expression. STAT6...
TMPY-04632	IL-15 Protein, Human, Recombinant	Human	E. coli
	The protein encoded by the IL15 gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common h...
TMPY-05004	FGF-4 Protein, Human, Recombinant	Human	E. coli
	FGF (fibroblast growth factor) signalling is known to be required for many aspects of mesoderm formation and patterning during Xenopus development and has been implicated in regulating genes required for the specificati...
TMPY-04572	MKK4 Protein, Mouse, Recombinant (His & GST)	Mouse	Baculovirus-Insect Cells
	Dual specificity mitogen-activated protein kinase kinase 4, also known as MAP kinase kinase 4, MAPKK4, JNK-activating kinase 1, MAPK/ERK kinase 4, SAPK/ERK kinase 1, c-Jun N-terminal kinase kinase 1, JNKK, and MAP2K4, is...
TMPY-01413	Cripto Protein, Human, Recombinant (His)	Human	HEK293
	Cripto/TDGF1 is a member of the epidermal growth factor (EGF)- Cripto, Frl-1, and Cryptic (CFC) family. EGF-CFC family member proteins share a variant EGF-like motif, a conserved cysteine-rich domain, and a C-terminal hy...
TMPY-03835	CDCP1 Protein, Rhesus, Recombinant (His)	Rhesus	HEK293
	CDCP1 contains three extracellular CUB domains. It is a putative stem cell marker that is highly expressed in some human cancer cells and both, typical and atypical (cancerous) colons. It interacts with CDH2/N-cadherin, ...
TMPY-04298	CDCP1 Protein, Human, Recombinant (His)	Human	HEK293
	CDCP1 contains three extracellular CUB domains. It is a putative stem cell marker that is highly expressed in some human cancer cells and both, typical and atypical (cancerous) colons. It interacts with CDH2/N-cadherin, ...
TMPY-01384	Endoglin/CD105 Protein, Human, Recombinant (His)	Human	HEK293
	Endoglin, also known as CD105, is a type I homodimeric transmembrane glycoprotein with a large, disulfide-linked, extracellular region and a short, constitutively phosphorylated cytoplasmic tail. Endoglin contains an RGD...
TMPY-02409	Siglec-3/CD33 Protein, Cynomolgus, Rhesus, Recombinant (His)	Cynomolgus,Rhesus	HEK293
	Myeloid cell surface antigen CD33 also known as Sialic acid binding Ig-like lectin 3, CD33 antigen or Siglec-3, is a member of the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. This S...
TMPY-03805	Siglec-3/CD33 Protein, Human, Recombinant (His)	Human	HEK293
	Myeloid cell surface antigen CD33 also known as Sialic acid binding Ig-like lectin 3, CD33 antigen or Siglec-3, is a member of the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. This S...
TMPY-04952	Siglec-3/CD33 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
	Myeloid cell surface antigen CD33 also known as Sialic acid binding Ig-like lectin 3, CD33 antigen or Siglec-3, is a member of the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. This S...
TMPY-02304	Siglec-3/CD33 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Myeloid cell surface antigen CD33 also known as Sialic acid binding Ig-like lectin 3, CD33 antigen or Siglec-3, is a member of the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. This S...
TMPY-01774	TREM-1 Protein, Human, Recombinant (His)	Human	HEK293
	TREM1 (triggering receptor expressed on myeloid cells) is a type I transmembrane protein with a single Ig-like domain, and is selectively expressed on blood neutrophils and a subset of monocytes. As a member of the growi...
TMPY-04805	Siglec-3/CD33 Protein, Human, Recombinant	Human	HEK293
	Myeloid cell surface antigen CD33 also known as Sialic acid binding Ig-like lectin 3, CD33 antigen or Siglec-3, is a member of the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. This S...
TMPY-01262	TROP-2 Protein, Human, Recombinant (His)	Human	HEK293
	TROP-2, also referred to as tumor-associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1, is a cell surface glycoprotein highly expressed in a wide variety of epithelial cancers. In contrast, there is little o...
TMPY-02087	IL-24 Protein, Human, Recombinant (His)	Human	HEK293
	Interleukin-24 (IL-24) also known as Melanoma differentiation-associated gene 7 protein (MDA-7) is a member of the IL10 family of cytokines. IL-24/MDA-7/IL24 can induce apoptosis selectively in various cancer cells. Over...
TMPY-05153	TROP-2 Protein, Cynomolgus, Rhesus, Recombinant (His)	Cynomolgus,Rhesus	HEK293
	TROP-2, also referred to as tumor-associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1, is a cell surface glycoprotein highly expressed in a wide variety of epithelial cancers. In contrast, there is little o...
TMPY-02667	TROP-2 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	TROP-2, also referred to as tumor-associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1, is a cell surface glycoprotein highly expressed in a wide variety of epithelial cancers. In contrast, there is little o...
TMPY-01146	Insulin Receptor Protein, Human, Recombinant (long isoform, His)	Human	HEK293
	INSR (Insulin receptor), also known as CD22, is a transmembrane receptor that is activated by insulin. INSR belongs to the protein kinase superfamily and exists as a tetramer consisting of two alpha subunits and two beta...
TMPY-02558	IL-4 Protein, Mouse, Recombinant	Mouse	E. coli
	Interleukin-4, also known as IL4, is a secreted protein that belongs to the IL-4 / IL-13 family. Interleukin-4 / IL4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation. It e...
TMPY-01458	GFR Alpha-3/GFRA3 Protein, Human, Recombinant (His)	Human	HEK293
	Glial cell line derived neurotrophic factor (GDNF) Family Receptor Alpha 3 (GFRA3) or GDNFRa3 is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF...
TMPY-00835	IGFBP-3 Protein, Human, Recombinant (His)	Human	HEK293
	The Insulin-like Growth Factor (IGF) signaling system plays a central role in cellular growth, differentiation, and proliferation. IGFBP3 is the most abundant IGF binding protein in human serum and is a growth inhibitory...
TMPY-01862	IL-4 Protein, Human, Recombinant	Human	E. coli
	Interleukin-4, also known as IL4, is a secreted protein that belongs to the IL-4 / IL-13 family. Interleukin-4 / IL4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation. It e...
TMPY-01750	HVEM Protein, Human, Recombinant (His)	Human	HEK293
	Herpesvirus entry mediator (HVEM), also referred to as TNFRSF14, TR2 (TNF receptor-like molecule) and ATAR (another TRAF-associated receptor), is a member of type I transmembrane protein belonging to the TNF-receptor sup...
TMPY-04396	C-ABL/ABL1 Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cy...
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DYRK3 Protein, Human, Recombinant (His & GST)

TMPY-04380

Species: Human

Expression System: Baculovirus-Insect Cells

HER3/ERBB3 Protein, Rat, Recombinant (His)

TMPY-03024

Species: Rat

Expression System: HEK293

HER3/ERBB3 Protein, Human, Recombinant (His), Biotinylated

TMPY-04956

Species: Human

Expression System: HEK293

HER3/ERBB3 Protein, Human, Recombinant (His)

TMPY-01389

Species: Human

Expression System: HEK293

HER3/ERBB3 Protein, Rhesus, Recombinant

TMPY-00246

Species: Rhesus

Expression System: HEK293

HER3/ERBB3 Protein, Human, Recombinant

TMPY-00399

Species: Human

Expression System: HEK293

HER3/ERBB3 Protein, Rhesus, Recombinant (His)

TMPY-02477

Species: Rhesus

Expression System: HEK293

HER3/ERBB3 Protein, Mouse, Recombinant (His)

TMPY-02365

Species: Mouse

Expression System: HEK293

CLEC-2 Protein, Mouse, Recombinant (hFc)

TMPY-00586

Species: Mouse

Expression System: HEK293

Prolactin Receptor Protein, Human, Recombinant (His)

TMPY-01053

Species: Human

Expression System: HEK293

ANXA2 Protein, Mouse, Recombinant (His)

TMPK-00785

Species: Mouse

Expression System: E. coli

VLDLR Protein, Human, Recombinant (His)

TMPY-01085

Species: Human

Expression System: HEK293

CD79B Protein, Human, Recombinant (hFc)

TMPJ-00113

Species: Human

Expression System: Human Cells

OGT Protein, Human, Recombinant (His & SUMO)

TMPH-00009

Species: Human

Expression System: E. coli

CDK4 Protein, Human, Recombinant (GST)

TMPY-04548

Species: Human

Expression System: Baculovirus-Insect Cells

GSK3B Protein, Human, Recombinant (His)

TMPY-04356

Species: Human

Expression System: Baculovirus-Insect Cells

SCF Protein, Mouse, Recombinant

TMPJ-00166

Species: Mouse

Expression System: E. coli

IL-10R alpha/IL-10RA Protein, Human, Recombinant (His)

TMPY-05338

Species: Human

Expression System: HEK293

IL-10R alpha/IL-10RA Protein, Mouse, Recombinant (hFc)

TMPY-05496

Species: Mouse

Expression System: HEK293

Src Protein, Human, Recombinant (His & GST)

TMPY-04384

Species: Human

Expression System: Baculovirus-Insect Cells

IFNAR1 Protein, Human, Recombinant (His)

TMPY-02647

Species: Human

Expression System: HEK293

Siglec-2/CD22 Protein, Mouse, Recombinant (His)

TMPY-04083

Species: Mouse

Expression System: HEK293

Siglec-2/CD22 Protein, Human, Recombinant (His, Solution)

TMPY-05566

Species: Human

Expression System: HEK293

Siglec-2/CD22 Protein, Human, Recombinant

TMPY-05201

Species: Human

Expression System: HEK293

Siglec-2/CD22 Protein, Human, Recombinant (His)

TMPY-02034

Species: Human

Expression System: HEK293

STAT6 Protein, Human, Recombinant (His)

TMPY-02603

Species: Human

Expression System: Baculovirus-Insect Cells

IL-15 Protein, Human, Recombinant

TMPY-04632

Species: Human

Expression System: E. coli

FGF-4 Protein, Human, Recombinant

TMPY-05004

Species: Human

Expression System: E. coli

MKK4 Protein, Mouse, Recombinant (His & GST)

TMPY-04572

Species: Mouse

Expression System: Baculovirus-Insect Cells

Cripto Protein, Human, Recombinant (His)

TMPY-01413

Species: Human

Expression System: HEK293

CDCP1 Protein, Rhesus, Recombinant (His)

TMPY-03835

Species: Rhesus

Expression System: HEK293

CDCP1 Protein, Human, Recombinant (His)

TMPY-04298

Species: Human

Expression System: HEK293

Endoglin/CD105 Protein, Human, Recombinant (His)

TMPY-01384

Species: Human

Expression System: HEK293

Siglec-3/CD33 Protein, Cynomolgus, Rhesus, Recombinant (His)

TMPY-02409

Species: Cynomolgus,Rhesus

Expression System: HEK293

Siglec-3/CD33 Protein, Human, Recombinant (His)

TMPY-03805

Species: Human

Expression System: HEK293

Siglec-3/CD33 Protein, Human, Recombinant (His), Biotinylated

TMPY-04952

Species: Human

Expression System: HEK293

Siglec-3/CD33 Protein, Mouse, Recombinant (His)

TMPY-02304

Species: Mouse

Expression System: HEK293

TREM-1 Protein, Human, Recombinant (His)

TMPY-01774

Species: Human

Expression System: HEK293

Siglec-3/CD33 Protein, Human, Recombinant

TMPY-04805

Species: Human

Expression System: HEK293

TROP-2 Protein, Human, Recombinant (His)

TMPY-01262

Species: Human

Expression System: HEK293

IL-24 Protein, Human, Recombinant (His)

TMPY-02087

Species: Human

Expression System: HEK293

TROP-2 Protein, Cynomolgus, Rhesus, Recombinant (His)

TMPY-05153

Species: Cynomolgus,Rhesus

Expression System: HEK293

TROP-2 Protein, Mouse, Recombinant (His)

TMPY-02667

Species: Mouse

Expression System: HEK293

Insulin Receptor Protein, Human, Recombinant (long isoform, His)

TMPY-01146

Species: Human

Expression System: HEK293

IL-4 Protein, Mouse, Recombinant

TMPY-02558

Species: Mouse

Expression System: E. coli

GFR Alpha-3/GFRA3 Protein, Human, Recombinant (His)

TMPY-01458

Species: Human

Expression System: HEK293

IGFBP-3 Protein, Human, Recombinant (His)

TMPY-00835

Species: Human

Expression System: HEK293

IL-4 Protein, Human, Recombinant

TMPY-01862

Species: Human

Expression System: E. coli

HVEM Protein, Human, Recombinant (His)

TMPY-01750

Species: Human

Expression System: HEK293

C-ABL/ABL1 Protein, Human, Recombinant (GST)

TMPY-04396

Species: Human

Expression System: Baculovirus-Insect Cells

--------- More ---------

Cat No.	Product Name
L2200	Tyrosine Kinase Inhibitor Library	1033 compounds
	A unique collection of 1033 tyrosine kinase inhibitors for high throughput screening and high content screening for drug discovery in tyrosine kinase related diseases;
L1600	Kinase Inhibitor Library	2720 compounds
	A unique collection of 2720 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;
L3500	Histone Modification Compound Library	480 compounds
	A unique collection of 480 histone modification related compounds for high throughput screening (HTS) and high content screening (HCS);
L1610	FDA-Approved Kinase Inhibitor Library	266 compounds
	A unique collection of 266 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.
L8100	Cell Cycle Compound Library	695 compounds
	A unique collection of 695 cell cycle related compounds for high throughput screening (HTS) and high content screening (HCS);
L1120	AMPK-Targeted Compound Library	80 compounds
	80 well-chosen unique AMPK-targeted small molecules；
L7200	Calcium Channel Compound Library	143 compounds
	A unique collection of 143 calcium channel blockers and agonists for high throughput and high content screening;
L2520	Glycometabolism Compound Library	708 compounds
	708 glycometabolism-related comounds, can be used for HTS and HCT;
L9840	Anti-Alzheimer's Disease Compound Library	1040 compounds
	A unique collection of 1040 compounds with anti-AD activities or acting on main drug targets of AD can be used for HTS and HCS.