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Cat No. | Product Name | Synonyms | Targets |
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T13047 | Synta66 | Calcium Channel | |
Synta66 is a store-operated calcium entry channel Orai inhibitor, and used for the research of neurological disease. | |||
T10885 | CRAC intermediate 2 | Others , Calcium Channel | |
CRAC intermediate 2 is a intermediate compound for CRAC inhibitor synthesis. | |||
T24984 | 5J-4 | Calcium Channel | |
5J-4 is a potent a blocker of calcium release-activated calcium (CRAC) channel and store-operated calcium entry (SOCE). 5J-4 reduces the production of IL-17 and decreases the expression of RORα and RORγt. | |||
T10884 | CRAC intermediate 1 | 5-(S)-Fluorowillardiine | Calcium Channel |
CRAC intermediate 1 (5-(S)-Fluorowillardiine) is a key intermediate in the chemical synthesis of a series of CRAC channel inhibitors. | |||
T3651 | YM-58483 | YM 58483,BTP2 | Calcium Channel |
YM-58483 (BTP2) is a specific and effective inhibitor of CRAC channels and subsequent Ca2+ signals. | |||
T25049 | Allethrin | BCL , Caspase | |
Allethrin induces oxidative stress, apoptosis and calcium release. Allethrin, a pyrethroid insecticide is a major mosquito repellent agent. | |||
T9000 | Pyrimorph | Antifungal | |
Pyrimorph is a fungicide with high activity against the plant pathogen Phytophthora capsici. Pyrimorph inhibited different stages in the life cycle of P. capsici including mycelial growth, sporangium production, zoospore... | |||
T8867 | RO2959 Hydrochloride | RO2959 HCl | IL Receptor , Calcium Channel , Interleukin |
RO2959 Hydrochloride (RO2959 HCl) is a potent and selective inhibitor of CRAC channel(IC50: 402 nM). It is also a potent inhibitor of human IL-2. | |||
T2343 | AS601245 | JNK | |
AS601245 is an inhibitor of the c-Jun NH2-terminal kinase (JNK), with neuroprotective properties. | |||
TQ0033 | Zegocractin | CM-4620,N-(5-(6-Chloro-2,2-difluorobenzo[d][1,3]dioxol-5-yl)pyrazin-2-yl)-2-fluoro-6-methylbenzamide,CM4620 | Calcium Channel |
Zegocractin (CM-4620) is a calcium-release activated calcium-channel (CRAC channel) inhibitor. | |||
T6800 | CCF642 | AC1LYELL | Others |
CCF642 (AC1LYELL) is a novel PDI-inhibiting compound with antimyeloma activity. | |||
T11217 | Eplivanserin | SR-46349 | 5-HT Receptor |
Eplivanserin (SR-46349) is an effective and selective antagonist of 5-HT2A receptor with a Kd of 1.14 nM and an IC50 value of 5.8 nM in rat cortical membrane. | |||
T2170 | SKF-96365 hydrochloride | SKF96365 | Apoptosis , Potassium Channel , Calcium Channel , TRP/TRPV Channel , Autophagy |
SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal Y cells. SKF-96365 hydrochloride can induce cytoprotective autopha... | |||
T1198 | Tetracaine hydrochloride | Amethocaine hydrochloride,Amethocalne HCl,Tetracaine HCl | Calcium Channel , Sodium Channel |
Tetracaine hydrochloride (Amethocalne HCl) (Pontocaine), a potent local anaesthetic, is a channel function allosteric inhibitor. It is primarily used as an antipruritic and topically in ophthalmology, and it has been use... | |||
T6928 | Pantoprazole | SKF96022,BY1023 | Apoptosis , Proton pump , Autophagy |
Pantoprazole (BY1023) is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease. | |||
T0161 | Pantoprazole Sodium Hydrate | SKF96022 sodium hydrate,BY1023 (sodium hydrate),SKF96022 (sodium hydrate) | Apoptosis , Potassium Channel , Proton pump , Autophagy |
Pantoprazole Sodium Hydrate (BY1023 (sodium hydrate)) is a proton pump inhibitor drug, used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease. | |||
T6929 | Pantoprazole sodium | Pantecta,SKF96022 sodium,SKF96022 (sodium),BY1023 (sodium),BY-1023 sodium,Pantoloc | Apoptosis , Others , Proton pump , HIF , Autophagy |
Pantoprazole sodium (Pantecta) is the sodium salt form of a substituted benzimidazole with proton pump inhibitor activity. Pantoprazole sodium is a lipophilic, weak base that crosses the parietal cell membrane and enters... | |||
T23434 | GPR35 agonist 2 | TC-G 1001 | GPR , Arrestin |
GPR35 agonist 2 (TC-G 1001) is a potent GPR35 agonist.The EC50 values of GPR35 agonist 2 in the β-arrestin and Ca2+ release assays were 26 and 3.2 nM, respectively. | |||
T0261 | Amcinonide | CL-34699 | Glucocorticoid Receptor , Annexin A |
Amcinonide (CL-34699) is a Corticosteroid. The mechanism of action of amcinonide is as a Corticosteroid Hormone Receptor Agonist. | |||
T16887 | Sipatrigine | 619C89,BW 619C89 | Calcium Channel , Sodium Channel |
Sipatrigine is a glutamate release inhibitor and voltage-dependent sodium channel. | |||
T15143 | DMP-543 | XR-543 | Others , Potassium Channel |
DMP-543 (XR-543) is a potassium channel (KV7 channel) blocker that enhances the release of neurotransmitters. | |||
T28136 | NC-1300-B | NC 1300 B | |
NC-1300-B is a proton pump. H(+)-K(+)-ATPase inhibition with NC-1300-B causes profound renal vasodilation and inhibition of renin release without affecting regulation of GFR. | |||
T12405 | Pentiapine | CGS 10746 | Dopamine Receptor |
Pentiapine (CGS 10746) is a novel inhibitor of dopamine release. | |||
T20206 | Oxymethurea | CSI Paste,Carbamol,Caurite,Dimethylolurea | Others |
Oxymethurea (CSI Paste) is a modified urea and can be used as in agricultural fields as a slow-release fertilizer. | |||
T7710 | MOFEBUTAZONE | Others | |
Mofebutazone inhibits the immunological release of prostaglandins as well as leukotrienes. | |||
T4313 | Tinoridine hydrochloride | Nonflamin,Y-3642 hydrochloride | COX , Glutathione Peroxidase |
Tinoridine hydrochloride (Y-3642 hydrochloride) is a non-steroidal anti-inflammatory drug. Tinoridine hydrochloride (5-100 μM), produced a concentration-dependent inhibition on the simultaneous increases in lipid peroxid... | |||
T7829 | FK962 | Somatostatin | |
FK962 is an somatostatin release enhancer , exerts cognitive-enhancing actions. | |||
TP2058L | Catestatin acetate | Catestatin acetate(142211-96-9 free base) | Endogenous Metabolite , AChR |
Catestatin acetate is a non-competitive antagonist of nAChR and inhibits catecholamine release. Catestatin acetate regulates cardiac function and blood pressure. | |||
T7065 | Tizanidine | Adrenergic Receptor | |
Tizanidine, an α2-adrenergic receptor agonist, suppresses the release of neurotransmitters from central nervous system (CNS) noradrenergic neurons. | |||
T19764 | Trepibutone | AA-149,Colibil, Supacal,AA149,AA 149 | Others |
Trepibutone (AA-149), an acidic drug, has the capability of pH-independent release. | |||
T9380L | Antide acetate | Antide acetate (112568-12-4 Free base) | LHRH |
Antide acetate is an LHRH antagonist and represses LH and FSH release from the pituitary gland. | |||
T23969 | DCAI | Others | |
DCAI is an inhibitor of nucleotide exchange and nucleotide release acting by binding to the pocket adjacent to the Ras-SOS interface. | |||
T8239 | Cromoglicic acid | Others | |
Cromoglicic acid prevents the release of inflammatory chemicals such as histamine from mast cells. | |||
T19893 | Thozalinone | Others | |
Thozalinone is a psychostimulant agent inducing the release of norepinephrine and dopamine. | |||
T77581 | KM02894 | GluR | |
KM02894 is a glutamate release inhibitor. Cancer cells release high levels of glutamate that can disrupt normal bone turnover, which can lead to cancer-induced bone pain.KM02894 may be used in the study of tumor-related ... | |||
T0173 | Nylidrin hydrochloride | Buphenine HCl | Adrenergic Receptor |
Nylidrin hydrochloride (Buphenine HCl) was an effective inhibitor of the IgG1-mediated release of histamine from passively sensitized guinea pig lung slices, and of the IgE-mediated release of histamine from passively se... | |||
T69757 | PDDC inhibitor | ||
PDDC is the first nSMase2 inhibitor that possesses both favorable pharmacodynamics and pharmacokinetic (PK) parameters, including substantial oral bioavailability, brain penetration, and significant inhibition of exosome... | |||
T61112 | SLF1081851 | LPL Receptor | |
SLF1081851 is a Spns2 inhibitor. SLF1081851 inhibits S1P release with IC50 of 1.93 μM. | |||
T5101 | BW-A 78U | BW-A78U | PDE |
BW-A 78U is a PDE4 inhibitor (IC50: 3 μM). It is not inhibition on the lipopolysaccharide (LPS)-induced TNF-α release. | |||
T0994 | Ketotifen fumarate | HC 20511 fumarate | PDE , Histamine Receptor |
Ketotifen fumarate (HC 20511 fumarate) is a cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. | |||
T7338 | DHBP dibromide | Diheptylviologen dibromide,1,1'-DI-N-HEPTYL-4,4'-BIPYRIDINIUM DIBRO | Calcium Channel |
DHBP dibromide (1,1'-DI-N-HEPTYL-4,4'-BIPYRIDINIUM DIBRO) is calcium release and a muscle relaxant inhibitor. | |||
T16816 | S 18986 | GluR | |
S 18986 is a selective, orally active, brain penetrant positive allosteric modulator of AMPA-type receptors, showcasing cognitive-enhancing properties in rodents. It induces the release of noradrenaline and acetylcholine... | |||
T1260 | Cromolyn sodium | Disodium Cromoglycate,FPL 670 (Cromolyn) Disodium,FPL-670,Sodium cromoglycate | Others , Potassium Channel , GSK-3 , Calcium Channel |
Cromolyn sodium (FPL-670) is a chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells. | |||
T26828 | BIT225 | BIT 225,BIT-225 | |
BIT-225 is a NCp7 zinc finger inhibitor. BIT225 inhibits HIV-1 replication in myeloid dendritic cells. BIT225 inhibits HIV-1 release from human macrophages. BIT225 inhibits bovine viral diarrhea virus in vitro and shows ... | |||
T15414 | GR 113808 | GR-113808 | 5-HT Receptor |
GR 113808 is a selective 5-HT4 receptor antagonist that inhibits 5-HT1B, 5-HT2A, 5-HT2C, and 5-HT3 receptors, and attenuates dopamine release. | |||
TP1342L | GnRH-I acetate | GnRH-I acetate(33515-09-2 free base) | Others |
GnRH-I acetate in release of biologically active Follicle-Stimulating Hormone (FSH) and Luteinizing Hormone (LH) in the blood. | |||
T6956L | Protirelin Acetate(24305-27-9 free base) | Thyroliberin Acetate,TRF Acetate,Synthetic thyrotropin-releasing hormone Acetate,Lopremone Acetate,pGlu-His-Pro-NH2 Acetate,TRH Acetate | Thyroid hormone receptor(THR) |
Protirelin Acetate(24305-27-9 free base) (Thyroliberin Acetate) is a tripeptide that stimulates the release of thyrotropin and prolactin. | |||
T15758 | Linopirdine | DuP 996 | Potassium Channel , TRP/TRPV Channel |
Linopirdine (DuP 996) is a TRPV1 agonist. Linopirdine is an orally active and selective M-type K+ current (IM; Kv7; KCNQ Channels) inhibitor (IC50: 2.4 μM). Linopirdine is a cognitive enhancer. It acts by stimulating rel... | |||
T33711L | Nolomirole HCl | CHF 1035 HCl,CHF 1035,CHF1035,CHF1035 HCl,CHF-1035 HCl,CHF-1035,Nolomirole Hydrochloride | Dopamine Receptor , Norepinephrine |
Nolomirole HCl (CHF 1035) is a novel selective dopamine agonist with oral activity and inhibitory effects on norepinephrine release, which can be used to study mild chronic heart failure. | |||
TP1325L | Gastrin-Releasing Peptide, human(TFA) | Others | |
Gastrin-Releasing Peptide (TFA) is a regulatory human peptide that elicits gastrin release and regulates gastric acid secretion and enteric motor function. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TN1213 | 2-(Hydroxymethyl)anthraquinone | Anti-infection | |
2-(Hydroxymethyl)anthraquinone exhibits strong activity against Helicobacter pylori ATCC 43504 at 0.01 mg/disc. | |||
T2946 | Tanshinone IIA sulfonate sodium | Tanshinone IIA sulfonate,Sodium Tanshinone IIA sulfonate,Tanshinone IIA sodium sulfonate,sodium | CaMK , P450 , Calcium Channel |
Tanshinone IIA sulfonate sodium (Tanshinone IIA sodium sulfonate) is a water-soluble derivative of tanshinone IIA extracted from Savia miltiorrhiza; a potent negative allosteric modulator of the human purinergic receptor... | |||
T13632 | D-Erythro-dihydrosphingosine | Dihydrosphingosine,Octadecasphinganine,C18-Dihydrosphingosine,D-erythro-Sphinganine | Phospholipase , Endogenous Metabolite |
D-Erythro-dihydrosphingosine (C18-Dihydrosphingosine) inhibits arachidonic acid release and cPLA2α activity. | |||
T8288 | 14-Deoxyandrographolide | Apoptosis , Others | |
14-Deoxyandrographolide is a bioactive compound of Andrographis paniculata with hepatoprotective efficacy. It desensitizes hepatocytes to TNF-α-mediated apoptosis through the release of TNFRSF1A release. | |||
T5S1389 | Escin IB | 5-HT Receptor , NO Synthase | |
Escin Ib inhibits gastric emptying, at least in part, mediated by capsaicin-sensitive sensory nerves, to stimulate the synthesis and/or release of dopamine, to act through central dopamine2 receptor, which in turn causes... | |||
T0927 | Butylparaben | Butyl 4-hydroxybenzoate,Butyl parahydroxybenzoate | Endogenous Metabolite , Antibacterial , Antibiotic |
Butylparaben (Butyl 4-hydroxybenzoate) is a standardized chemical allergen, increasing histamine release, and cell-mediated immunity. | |||
T6956 | Protirelin | Lopremone,pGlu-His-Pro-NH2,Synthetic thyrotropin-releasing hormone,Thyroliberin,TRH,TRF | Thyroid hormone receptor(THR) , Endogenous Metabolite |
Protirelin (Thyroliberin) is a tripeptide that stimulates the release of thyrotropin and prolactin. | |||
TCS1188 | Mogroside III | Others | |
Mogroside III is a triterpenoid glycoside and a nonsugar sweetener. Mogroside III is transformed by human intestinal bacteria to release secondary glycoside mogroside IIA1 and aglycone mogrol. | |||
T5S1286 | (+)-Columbianetin | (S)-Columbianetin,Columbianetin | Antifungal |
(+)-Columbianetin ((S)-Columbianetin) is a new phytoalexin associated with celery (Apium graveolens) resistance to pathogens during storage, it also has antifungal activity. (+)-Columbianetin has anti-inflammatory effect... | |||
T1297 | Eugenol | 4-Allylguaiacol,Allylguaiacol,4-Allyl-2-methoxyphenol,Eugenic acid | Apoptosis , Ferroptosis , Reactive Oxygen Species , Antibacterial , Parasite |
Eugenol (Allylguaiacol) is a Standardized Chemical Allergen. The physiologic effect of eugenol is by means of Increased Histamine Release and Cell-mediated Immunity. | |||
T2793 | Tetrahydropalmatine | DL-Tetrahydropalmatine,Rotundine | Apoptosis , Others , Dopamine Receptor |
Tetrahydropalmatine (DL-Tetrahydropalmatine) is an active component isolated from corydalis, suppressing amygdaloid release of dopamine to inhibit an epileptic attack in rats. | |||
T3912 | Saikosaponin B1 | Others | |
Saponin activator. Activates release of Prostaglandin E2 in vitro. Anti-inflammatory agent. Orally active. Active in vivo and in vitro. | |||
T0908 | Chlorquinaldol | 5,7-Dichloro-8-hydroxy-2-methylquinoline,Chloquinan | Antibacterial , Antibiotic , Antifungal |
Chlorquinaldol (5,7-Dichloro-8-hydroxy-2-methylquinoline) is a Standardized Chemical Allergen. The physiologic effect of chlorquinaldol is by means of Increased Histamine Release, and Cell-mediated Immunity. | |||
T2S1086 | Nepitrin | Nepetin-7-glucoside | Antioxidant |
1. Nepitrin (Nepetin-7-glucoside) has antioxidant activity in human HL6 cells assessed as reduction of cytochrome-c release, DPPH free radical scavenging activity, and inhibition of TPA-induced free radical formation. | |||
T7060 | Amantadine | 1-Aminoadamantane,1-Adamantanamine,1-Adamantylamine | Others |
Amantadine (1-Aminoadamantane) is an antiviral, is a weak antagonist of the NMDA-type glutamate receptor, increases dopamine release, and blocks dopamine reuptake. | |||
T0834 | Ethylparaben | Ethyl 4-hydroxybenzoate,Ethyl parahydroxybenzoate | Antibacterial , Antifungal |
Ethylparaben (Ethyl parahydroxybenzoate) is a Standardized Chemical Allergen. The physiologic effect of ethylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity. | |||
T3903 | Angoroside C | Prostaglandin Receptor | |
Angoroside C is a Potential anti-inflammatory compound. Inhibitor of prostaglandin E2 release in mouse peritoneal macrophages in vitro. Shows potent antioxidative activity in reducing the oxidized OH adducts of dAMP and ... | |||
T2A2497 | L-Glutamic acid | (S)-Glutamic acid,glutamic acid,(+)-L-Glutamic acid,Aciglut,glutacid,Glutaminol | Apoptosis , Ferroptosis , Endogenous Metabolite , iGluR |
L-Glutamic acid (Glutaminol) acts as an excitatory transmitter, shows a direct activating effect on the release of DA from dopaminergic terminals. | |||
TN1740 | Homoeriodictyol | 5-HT Receptor , transporter , Sodium Channel , Drug Metabolite | |
Homoeriodictyol, a naturally occurring, bitter-masking flavanone, as a promising agent to increase appetite and food intake. The flavanone homoeriodictyol can increase SGLT-1-mediated glucose uptake but decrease serotoni... | |||
TN1081 | Hirsuteine | Dopamine Receptor | |
Hirsuteine is a natural product. It non-competitively antagonizes nicotine-mediated dopamine release by blocking ion permeation through nicotinic receptor channel complexes. | |||
TN6962 | Docosane | Others | |
Docosane [Standard Material for GC] is a natural product. | |||
T4S1876 | 3-Deoxyaconitine | Sodium Channel | |
3- Deoxyaconitine is a derivative of Aconitine (A189875), which activates tetrodotoxin-sensitive Na+ channels, inducing presynaptic depolarization, thus blocking the nerve action potential which, in turn, blocks the rele... | |||
TN1154 | Nepetin | 6-Methoxyluteolin | Calcium Channel , Histamine Receptor |
Nepetin (6-Methoxyluteolin) has antioxidant activity, it is a potent inhibitor of histamine release and calcium influx via down-regulation of the FcεRI α chain. | |||
T4940 | 3-Methylhistamine dihydrochloride | Others , Endogenous Metabolite | |
N tau-methylhistamine is one of the histamine metabolites. N tau-methylhistamine in plasma and urine is a good parameter for histamine release, and the determination of this histamine metabolite is generally less hampere... | |||
T5758 | Sphondin | COX , Prostaglandin Receptor | |
Sphondin has anticonvulsant, anti-inflammatory, and anti-proliferative activities, it possessed an inhibitory effect on IL-1beta-induced increase in the level of COX-2 protein and PGE(2) release in A549 cells. | |||
T3S1641 | Esculentoside H | TNF , NF-κB , JNK | |
Phytolaccaceae has anti-tumor activity, the mechanism may be related to the capacity of Esculentoside H for TNF release. | |||
TN1949 | Moracin C | ROS , NO Synthase | |
Moracin C, a natural compound found in Morus mesozygia, Morus alba var. multicaulis, is an anti-inflammatory agent. moracin C inhibits nitric oxide (NO) release and LPS-activated reactive oxygen species (ROS) in cells. | |||
T9143 | D-Isoleucine | (2R,3R)-2-Amino-3-methylpentanoic acid,(R)-Isoleucine | Others |
D-Isoleucine ((2R,3R)-2-Amino-3-methylpentanoic acid) is a selective activator of Asc-1 antiporter, which enhances long-term potentiation at the hippocampal CA1-CA3 via release of endogenous D-serine. | |||
T6S0840 | Engeletin | Dihydrokaempferol 3-rhamnoside | NF-κB , Reductase |
1. Engeletin (Dihydrokaempferol 3-rhamnoside) may serve as a potential anti-inflammatory agent. 2. Engeletin possesses potent inhibition of PGE2 release with IC5 values of 19.6 μg/ml. 3. Engeletin inhibits a recombinant ... | |||
TN1051 | 1-Caffeoylquinic acid | NF-κB | |
1-Caffeoylquinic acid is an important intermediate in lignin biosynthesis. 1-Caffeoylquinic acid has anti-influenza, and antioxidant activities, it also slows the release of glucose into the bloodstream after a meal. | |||
T6926 | Palmitoylethanolamide | Mackpeart DR 14V,N-palmitoylethanolamine,Loramine P 256,Impulsin,AM 3112,Palmidrol | Influenza Virus , Endogenous Metabolite , PPAR |
Palmitoylethanolamide (Impulsin) is an endogenously fatty acid amide. It has a role as an anti-inflammatory drug, an antihypertensive agent, a neuroprotective agent and an anticonvulsant.Upon administration, palmitoyleth... | |||
TN1721 | Gypenoside L | ERK , p38 MAPK , Calcium Channel , NF-κB , ROS | |
Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through endoplasm reticulum stress-mediated Ca2+ release. It also inhibit non-small cell lung carcinoma A549 cell inhibitory a... | |||
T0465 | Ellagic acid | Gallogen,Elagostasine | Hedgehog/Smoothened , Casein Kinase , Reactive Oxygen Species , Topoisomerase , Endogenous Metabolite , PKA , Syk , PKC , Carbonic Anhydrase |
Ellagic acid (Gallogen) is a fused four ring compound isolated from the kino of Eucalyptus maculata Hook and E. Hemipholia F. Muell. Activates Factor XII of the blood clotting system which also causes kinin release; used... | |||
T3095 | Tyramine | 4-hydroxyphenethylamine,para-tyramine,p-Tyramine,mydrial,Tocosine,Uteramine | MAO , Endogenous Metabolite |
Tyramine (Uteramine) is an indirect sympathomimetic that occurs naturally in cheese and other foods. Tyramine does not directly activate adrenergic receptors, but it can serve as a substrate for adrenergic uptake systems... | |||
T3902 | Atractylenolide III | ICodonolactone,8β-Hydroxyasterolide | Apoptosis |
Atractylenolide III (ICodonolactone) may have therapeutic potential in treating homocysteine-mediated cognitive impairment and neuronal injury. Atractylenolide III is a potential candidate for the treatment of human lung... | |||
T4S0779 | D-tetrahydropalmatine | Others , Dopamine Receptor | |
D-Tetrahydropalmatine is a organic cation transporter 1 (OCT1) inhibitor, it can obviously inhibit the uptake of monocrotaline (MCT) in MDCK-hOCT1 cells and isolate rat primary hepatocytes, and attenuate the viability re... | |||
TN1275 | P-Hydroxyphenethyl anisate | 4-Hydroxyphenethylanisate | Others |
p-Hydroxyphenethyl anisate (4-Hydroxyphenethylanisate), a natural product from Notopterygium forbe-siiBoiss, is a novel polymeric sustained-release material that, after block copolymerization with AAPBA, produces nanopar... | |||
TN1661 | Ganoderic acid C2 | Reductase , Histamine Receptor , Immunology/Inflammation related | |
Ganoderic acid C2 has anti-inflammatory,and anti-tumor-promoting activities. Ganoderic acid C2 can inhibit histamine release, it also has inhibitory effects on the induction of Epstein-Barr Virus early antigen. | |||
TN1065 | Hirsutine | Apoptosis | |
Hirsutine induces apoptosis and is a potent Dengue virus inhibitor exhibiting low cytotoxicity.Hirsutine has anticancer, cardioprotective, anti-hypertensive and anti-arrhythmic activities, it also has vasodilatation acti... | |||
TN7224 | 2,2'-Dihydroxy chalcone | Antibacterial , Autophagy | |
2,2'-Dihydroxy chalcone is a potent inhibitor of β-glucuronidase (IC50=1.6±0.2 μM) and lysozyme (IC50=1.4±0.2 μM) release from rat neutrophils stimulated with fMLP/CB.2,2'-Dihydroxy chalcone has inhibitory activity again... | |||
T6S0077 | Byakangelicol | COX | |
1. Byakangelicol may inhibit P-gp expressed at the BBB even under in vivo conditions. 2. Byakangelicol can inhibit IL-1beta-induced PGE2 release in A549 cells; this inhibition may be mediated by suppression of COX-2 expr... | |||
T5227 | Tricaprin | Tridecanoin,Glyceryl tridecanoate,Glycerol Tridecanoate,TG(10:0/10:0/10:0),Glycerol tricaprate | Others , Endogenous Metabolite |
Tricaprin (Glycerol Tridecanoate) is also known as triacylglycerols or triacylglycerides. The triglycerides are rebuilt in the blood from their fragments and become constituents of lipoproteins, which deliver the fatty a... | |||
T1257 | Bestatin | Ubenimex | Others , Aminopeptidase , Antibacterial , Antibiotic , LTR |
Bestatin (Ubenimex) competitively inhibits many aminopeptidases, including B, N and leucine aminopeptidases. Ubenimex is a microbial metabolite and dipeptide with potential immunomodulatory and antitumor activities. Amin... | |||
T2909 | Fraxetin | 7,8-dihydroxy-6-methoxy coumarin | Apoptosis , Others |
Fraxetin (7,8-dihydroxy-6-methoxy coumarin) has dual-antioxidative ,hepatoprotective and antihyperglycemic functions, it shows potent protective effects against CCl4 induced oxidative stress and hepatic fibrosis, has a m... | |||
TN2080 | Pinoresinol | (+)-Pinoresinol | Apoptosis , NF-κB , CDK , p53 |
Pinoresinol ((+)-Pinoresinol) has antiinflammatory, hepatoprotective, and fungicidal activities, it can protect pial microcirculation from I-reperfusion injury, to increase nitric oxide release and to reduce oxidative st... | |||
T3728 | Methyl Paraben | Methyl parahydroxybenzoate,Nipagin,Methylparaben,Methyl 4-hydroxybenzoate,Methyl p-hydroxybenzoate | Endogenous Metabolite , Antibacterial , Antibiotic |
The physiologic effect of Methyl Paraben (Nipagin) is by means of Increased Histamine Release, and Cell-mediated Immunity. Methyl Paraben (Nipagin) is an antimicrobial agent, preservative, flavouring agent. Methyl Parabe... | |||
T38248 | 2-Ethylpyrazine | Endogenous Metabolite , NO Synthase | |
2-Ethylpyrazine is present in roasted coffee beans and is a volatile compound .2-Ethylpyrazine induces vasodilation through the activity of endothelium-derived relaxing factors.2-Ethylpyrazine activates NO synthesis thro... | |||
T1208 | Citicoline sodium | Citicoline sodium salt,CDP-choline | Apoptosis , Others , Endogenous Metabolite |
Citicoline sodium (CDP-choline) is an endogenous intermediate in the synthesis of phosphatidylcholine. It also serves as a choline donor in the biosynthesis of the neurotransmitter acetylcholine. Citicoline sodium demons... | |||
T4904 | 1-Methylguanidine hydrochloride | Others , Endogenous Metabolite | |
Methylguanidine (MG) is a guanidine compound deriving from protein catabolism. It is also a product of putrefaction. Methylguanidine is a suspected uraemic toxin that accumulates in renal failure, however it also exhibit... | |||
T3889 | Platycodin D | Prostaglandin Receptor , AMPK | |
Platycodin D may stimulate TNF-α synthesis or inhibit degradation of TNF-α mRNA. Platycodin D (10/30 μM) suppresses prostaglandin E2 production in rat peritoneal macrophages stimulated by the protein kinase C activator 1... | |||
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Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-01279 | CRACR2B Protein, Human, Recombinant (His) | Human | E. coli |
Plays a role in store-operated Ca(2+) entry (SOCE). | |||
TMPJ-00994 | LTBR Protein, Mouse, Recombinant (hFc) | Mouse | Human Cells |
It is a single-pass type I membrane protein and contains 4 TNFR-Cys repeats. The protein is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including ce... | |||
TMPY-05039 | LTBR Protein, Human, Recombinant (hFc) | Human | HEK293 |
LTBR (lymphotoxin beta receptor (TNFR superfamily, member 3)) is a member of the tumor necrosis factor (TNF) family of receptors. The tumor necrosis factor receptor is a trimeric cytokine receptor that binds tumor necros... | |||
TMPH-00010 | MMP-14 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Endopeptidase that degrades various components of the extracellular matrix such as collagen. Activates progelatinase A. Essential for pericellular collagenolysis and modeling of skeletal and extraskeletal connective tiss... | |||
TMPJ-01471 | Activin A Protein, Human, Mouse, Rat, Cynomolgus, Rhesus, Recombinant | Human/Mouse/Rat | Human Cells |
Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. Activins, members of the TGF-beta superfamily, are disulfide-linked dimeric proteins originally purifi... | |||
TMPJ-00147 | FOLR1 Protein, Human, Recombinant (hFc) | Human | Human Cells |
Folate receptor alpha(FOLR) belongs to the folate receptor family, and is primarily expressed in tissues of epithelial origin. It is also expressed in kidney, lung and cerebellum. The secreted form is derived from the me... | |||
TMPJ-00327 | M-CSF/CSF1 Protein, Human, Recombinant (His) | Human | Human Cells |
Macrophage Colony-Stimulating Factors (m-csf) are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and th... | |||
TMPY-04727 | GDF-15 Protein, Human, Recombinant (His) | Human | Yeast |
Growth-differentiation factor 15 (GDF15), also known as MIC-1, is a secreted member of the transforming growth factor (TGF)-β superfamily, as a novel antihypertrophic regulatory factor in the heart. GDF-15 / GDF15 is not... | |||
TMPY-01073 | GDF-15 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Growth-differentiation factor 15 (GDF15), also known as MIC-1, is a secreted member of the transforming growth factor (TGF)-β superfamily, as a novel antihypertrophic regulatory factor in the heart. GDF-15 / GDF15 is not... | |||
TMPY-00672 | Azurocidin/CAP37 Protein, Human, Recombinant (His) | Human | HEK293 |
Azurocidin (AZU1), also known as heparin-binding protein (HBP) or cationic antimicrobial protein 37 (CAP37), is an azurophil granule antibiotic protein, with monocyte chemotactic and antibacterial activity. The Azurophil... | |||
TMPY-04902 | Complement C5a Protein, Mouse, Recombinant | Mouse | E. coli |
C5a is a protein fragment released from complement component C5. This 74 amino acid peptide in humans is generated by the cleavage of C5a convertase on the C5 α-chain during the classical, alternative, and lectin pathway... | |||
TMPY-05057 | Complement C5 Protein, Human, Recombinant (His & FLAG) | Human | HEK293 |
C5a is a protein fragment released from complement component C5. This 74 amino acid peptide in humans is generated by the cleavage of C5a convertase on the C5 α-chain during the classical, alternative, and lectin pathway... | |||
TMPY-00653 | Complement C5 Protein, Human, Recombinant (Complement C5a) | Human | E. coli |
C5a is a protein fragment released from complement component C5. This 74 amino acid peptide in humans is generated by the cleavage of C5a convertase on the C5 α-chain during the classical, alternative, and lectin pathway... | |||
TMPY-03054 | Fc epsilon RI Protein, Human, Recombinant (His) | Human | HEK293 |
FcERI, also known as FCER1A, is the alpha subunit of the immunoglobulin epsilon receptor (IgE receptor). IgE receptor is a high affinity IgE receptor which plays a central role in allergic disease, coupling allergen and ... | |||
TMPY-05084 | Fc epsilon RI Protein, Human, Recombinant | Human | HEK293 |
FcERI, also known as FCER1A, is the alpha subunit of the immunoglobulin epsilon receptor (IgE receptor). IgE receptor is a high affinity IgE receptor which plays a central role in allergic disease, coupling allergen and ... | |||
TMPY-04625 | SEMA3A Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Semaphorins are a family of secreted and cell-bound signaling molecules defined by the presence of a common 5 aa Sema domain. They are best characterized in relation to axon guidance during development of the nervous sys... | |||
TMPY-00124 | SEMA3A Protein, Human, Recombinant (hFc) | Human | HEK293 |
Semaphorins are a family of secreted and cell-bound signaling molecules defined by the presence of a common 5 aa Sema domain. They are best characterized in relation to axon guidance during development of the nervous sys... | |||
TMPJ-00137 | APRIL/TNFSF13 Protein, Human, Recombinant (Flag & His) | Human | Human Cells |
APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily. It is synthesized as a 32 kDa proprotein which is cleaved by furin in the Golgi to relea... | |||
TMPY-03722 | EpCAM/TROP1 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Epithelial Cell Adhesion Molecule (EpCAM), also known as GA733-2 antigen, is a type I transmembrane glycoprotein composed of an extracellular domain with two EGF-Like repeats and a cystenin-rich region, a transmembrane d... | |||
TMPY-02443 | HSP70 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
HSPA1A is a member of the Hsp70 protein family. The 70 kilodalton heat shock proteins (Hsp70s) are a family of ubiquitously expressed heat shock proteins. HSP are abundant and conserved proteins present in all cells. Upo... | |||
TMPY-05587 | EpCAM/TROP1 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
Epithelial Cell Adhesion Molecule (EpCAM), also known as GA733-2 antigen, is a type I transmembrane glycoprotein composed of an extracellular domain with two EGF-Like repeats and a cystenin-rich region, a transmembrane d... | |||
TMPY-01300 | EpCAM/TROP1 Protein, Human, Recombinant (His) | Human | HEK293 |
Epithelial Cell Adhesion Molecule (EpCAM), also known as GA733-2 antigen, is a type I transmembrane glycoprotein composed of an extracellular domain with two EGF-Like repeats and a cystenin-rich region, a transmembrane d... | |||
TMPY-00854 | IL-1 alpha/IL-1A Protein, Human, Recombinant | Human | HEK293 |
IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proli... | |||
TMPY-03481 | IL-1R2 Protein, Human, Recombinant | Human | HEK293 |
Interleukin 1 receptor, type II (IL1R2) also known as CD121b (Cluster of Differentiation 121b) is a cytokine receptor that belongs to the interleukin-1 receptor family. This protein binds interleukin alpha (IL1A), interl... | |||
TMPY-06981 | IL-1 alpha/IL-1A Protein, Human, Recombinant (E. coli) | Human | E. coli |
IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proli... | |||
TMPY-01738 | IL-1 alpha/IL-1A Protein, Mouse, Recombinant | Mouse | E. coli |
IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proli... | |||
TMPY-02700 | BCL2 Protein, Human, Recombinant (His) | Human | E. coli |
BCL2 (B-cell leukemia/lymphoma 2, N-Histidine-tagged), also known as Bcl-2, belongs to the Bcl-2 family. Bcl-2 family proteins regulate and contribute to programmed cell death or apoptosis. It is a large protein family a... | |||
TMPY-03079 | IL-1R2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Interleukin 1 receptor, type II (IL1R2) also known as CD121b (Cluster of Differentiation 121b) is a cytokine receptor that belongs to the interleukin-1 receptor family. This protein binds interleukin alpha (IL1A), interl... | |||
TMPY-00716 | CD89 Protein, Human, Recombinant (His) | Human | HEK293 |
FCAR, also called FcαRI or CD89, is a type I transmembrane receptor for Fc region of IgA which is the most abundant immunoglobulin in mucosal areas but is only the second most common antibody isotype in serum. This recep... | |||
TMPY-01366 | IL-1R2 Protein, Human, Recombinant (His) | Human | HEK293 |
Interleukin 1 receptor, type II (IL1R2) also known as CD121b (Cluster of Differentiation 121b) is a cytokine receptor that belongs to the interleukin-1 receptor family. This protein binds interleukin alpha (IL1A), interl... | |||
TMPY-02614 | NGFR/p75NTR Protein, Human, Recombinant (hFc) | Human | HEK293 |
Nerve growth factor receptors (NGFRs) belong to a large growth factor receptor family. NGFR includes two types of receptors: high-affinity nerve growth factor receptor and low-affinity nerve growth factor receptor. The h... | |||
TMPY-05556 | Adiponectin Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Adiponectin (ADIPOQ), or 30 kDa adipocyte complement-related protein (Acrp30) is a protein secreted by adipose tissue, which acts to reduce insulin resistance and atherogenic damage, but it also exerts actions in other t... | |||
TMPJ-00042 | TSLP Protein, Human, Recombinant | Human | E. coli |
Thymic stromal lymphopoietin (TSLP) is a novel member of the hemopoietic cytokine family that promotes the development of B cells and shares overlapping activity with IL-7. The human TSLP protein comprises a 28 amino aci... | |||
TMPY-02848 | Adiponectin Protein, Human, Recombinant (hFc) | Human | HEK293 |
Adiponectin (ADIPOQ), or 30 kDa adipocyte complement-related protein (Acrp30) is a protein secreted by adipose tissue, which acts to reduce insulin resistance and atherogenic damage, but it also exerts actions in other t... | |||
TMPY-00916 | Antithrombin III Protein, Human, Recombinant (His) | Human | HEK293 |
SerpinC1, also known as antithrombin III (AT III), is a member of the serpin superfamily of serine protease inhibitors, and has been found to be a marker for disseminated intravascular coagulation (DIC) and to be of prog... | |||
TMPY-02245 | SNAP-25 Protein, Human, Recombinant (His) | Human | E. coli |
Synaptosomal-associated protein 25, also known as Super protein, Synaptosomal-associated 25 kDa protein, SNAP25 and SNAP, is a cytoplasm and cell membrane protein that belongs to the SNAP-25 family. SNAP25 / SUP contains... | |||
TMPY-04116 | KRAS Protein,Human,Recombinant(G12C & Q61H, His) | Human | E. coli |
K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec... | |||
TMPY-02431 | BCL-XL Protein, Human, Recombinant (His) | Human | E. coli |
B-cell lymphoma-extra large (Bcl-xl) is a transmembrane molecule in the mitochondria. Bcl-xL (BCL2L1), belongs to the Bcl-2 family. Members of the bcl-2 family encode proteins that function either to promote or to inhibi... | |||
TMPY-01357 | S100A9 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that... | |||
TMPY-01888 | KRAS Protein,Human, Recombinant (Q61H, His) | Human | E. coli |
K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec... | |||
TMPY-06056 | KRAS Protein, Human, Recombinant (G12D, His) | Human | E. coli |
K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec... | |||
TMPY-01278 | Apolipoprotein H/APOH Protein, Human, Recombinant (His) | Human | HEK293 |
Apolipoprotein H (APOH), also known as Beta-2-glycoprotein 1, Activated protein C-binding protein, B2GPI, and B2G1, is a glycoprotein synthesized by liver cells and it is present in the blood associated with plasma lipop... | |||
TMPY-04113 | KRAS Protein,Human,Recombinant(G12D & Q61H, His) | Human | E. coli |
K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec... | |||
TMPY-01938 | CD98 Protein, Human, Recombinant (His) | Human | HEK293 |
4F2 cell-surface antigen heavy chain, also known as 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, CD98, SLC3A2 and MDU1, is a single-pass type I I membrane protein that belongs to the SLC3A tr... | |||
TMPY-02358 | CD98 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
4F2 cell-surface antigen heavy chain, also known as 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, CD98, SLC3A2 and MDU1, is a single-pass type I I membrane protein that belongs to the SLC3A tr... | |||
TMPY-01279 | Transferrin Protein, Human, Recombinant (His) | Human | HEK293 |
Transferrin is a glycoprotein with an approximate molecular weight of 76.5 kDa. This glycoprotein is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C an... | |||
TMPJ-01391 | BAFF/TNFSF13B Protein, Mouse, Recombinant (mFc) | Mouse | Human Cells |
TNFSF13B/TNFSF20 belongs to the tumor necrosis factor family. It abundantly is expressed in peripheral blood Leukocytes and is specifically expressed in monocytes and macrophages. Also found in the spleen, lymph node, bo... | |||
TMPY-03295 | Transferrin Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Transferrin is a glycoprotein with an approximate molecular weight of 76.5 kDa. This glycoprotein is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C an... | |||
TMPY-06066 | Influenza A H3N2 (A/Kansas/14/2017) Neuraminidase/NA Protein (His) | H3N2 | Baculovirus-Insect Cells |
Neuraminidases are enzymes that cleave sialic acid groups from glycoproteins. Influenza neuraminidase is a type of neuraminidase found on the surface of influenza viruses that enables the virus to be released from the ho... | |||
TMPY-02336 | Influenza A H3N2 (A/Babol/36/2005) Neuraminidase/NA Protein (His) | H3N2 | HEK293 |
Neuraminidases are enzymes that cleave sialic acid groups from glycoproteins. Influenza neuraminidase is a type of neuraminidase found on the surface of influenza viruses that enables the virus to be released from the ho... | |||
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Cat No. | Product Name | ||
---|---|---|---|
L8720 | Pyroptosis Compound Library | 1077 compounds | |
1077 types of active small molecules associated with pyroptosis for high-throughput and high-content screening. | |||
L7300 | Potassium Channel Blocker Library | 160 compounds | |
A unique collection of 160 potassium channel blockers and agonists for high throughput and high content screening; | |||
L2400 | Endocrinology-Hormone Compound Library | 813 compounds | |
A unique collection of 813 compounds targeting endocrine system for high throughput screening (HTS) and high content screening (HCS) for new drugs; | |||
L5400 | Anti-Cardiovascular Disease Compound Library | 1428 compounds | |
A unique collection of 1428 cardiovascular diseases related compounds for high throughput screening (HTS) and high content screening (HCS); | |||
L6140 | Saccharide and Glycoside Natural Product Library | 364 compounds | |
A unique collection of 364 saccharides and glycosides compounds can be used for HTS and HCS; | |||
L7200 | Calcium Channel Compound Library | 143 compounds | |
A unique collection of 143 calcium channel blockers and agonists for high throughput and high content screening; | |||
L9840 | Anti-Alzheimer's Disease Compound Library | 1040 compounds | |
A unique collection of 1040 compounds with anti-AD activities or acting on main drug targets of AD can be used for HTS and HCS. | |||
L7110 | Anti-Hypertension Compound Library | 719 compounds | |
719 hypertension-related small molecules for high-throughput and high-content screening. |