Home Tools
Log in
Products Inhibitors Libraries Kits Services Contact Us
Cart
Peptides Monoclonal Antibodies Dye Reagents PROTAC Virtual Screening Targetmol Kits Cell Counting Kit-8 (CCK-8) Inhibitor Cocktails Natural Products Phenols Alkaloids Flavonoids
Inhibitors Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling
MAPK Membrane transporter/Ion channel Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome Stem Cells Tyrosine Kinase/Adaptors Ubiquitination Others
Compound Libraries Focused Bioactive Libraries General Bioactive Libraries Approved / Repurposing Disease Focused Target / Pathway Focused Characteristic Bioactive Libraries Natural Product Libraries Natural Product Library for HTS Characteristic Natural Product Libraries Natural Product Derivatives Libraries Natural Product Library for CADD Drug-like Compound Libraries Fragment Libraries Custom Compound Library
Signaling Pathways Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling
DNA Damage/DNA Repair Endocrinology/Hormones GPCR/G Protein Immunology/Inflammation JAK/STAT signaling MAPK Membrane transporter/Ion channel
Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome
Stem Cells Tyrosine Kinase/Adaptors Ubiquitination
Focused Bioactive Libraries General Bioactive Libraries Approved / Repurposing Disease Focused Target / Pathway Focused Characteristic Bioactive Libraries
Natural Product Libraries Natural Product Library for HTS Characteristic Natural Product Libraries Natural Product Derivatives Libraries Natural Product Library for CADD
Drug-like Compound Libraries Compound Libraries for HTS/HCS
Fragment Libraries General Fragment Libraries Characteristic Fragment Libraries Custom Compound Library

Search Result

Search Results for "release"

Targets

Cytokine release

Libraries

Pyroptosis Compound Library Potassium Channel Blocker Library Endocrinology-Hormone Compound Library Anti-Cardiovascular Disease Compound Library Calcium Antagonist Library Saccharide and Glycoside Natural Product Library Anti-Alzheimer's Disease Compound Library Anti-Hypertension Compound Library
------------------------More------------------------

Compounds

Cat No. Product Name
T13047 Synta66 Calcium Channel
Synta66 是一种钙池操纵钙离子通道 Orai 抑制剂，用于神经系统疾病的研究。
T24984 5J-4 Calcium Channel
5J-4 是一种有效的钙释放激活钙通道 (CRAC) 和钙池操纵性钙内流(SOCE) 阻滞剂。 5J-4 减少 IL-17 的产生并降低 RORα 和 RORγt 的表达。
T3651 YM-58483 YM 58483,BTP2 Calcium Channel
YM58483 是一种特异性有效的 CRAC 通道和随后的 Ca2+ 信号抑制剂，可阻断钙池操纵的阳离子内流 (SOCE)。
TQ0033 Zegocractin CM4620,N-(5-(6-Chloro-2,2-difluorobenzo[d][1,3]dioxol-5-yl)pyrazin-2-yl)-2-fluoro-6-methylbenzamide,CM-4620 Calcium Channel
CM-4620 是一种钙离子释放激活通道的抑制剂，对Orai1/STIM1和Orai2/STIM1的IC50值分别为 119 和 895 nM。
T25049 Allethrin Caspase , BCL
Allethrin 是拟除虫菊酯杀虫剂，是主要的驱蚊剂。它在大鼠睾丸癌细胞 (LC540) 中诱导氧化应激、细胞凋亡和钙释放。它还诱导 BCL-2、caspase-3 激活和细胞内钙的释放。
T10885 CRAC intermediate 2 Calcium Channel , Others
CRAC intermediate 2是CRAC 抑制剂合成的中间体化合物，详细信息来自专利WO 2013059666A1。
T10884 CRAC intermediate 1 5-(S)-Fluorowillardiine Calcium Channel
CRAC intermediate 1是用于CRAC 离子通道系列化合物合成的关键中间体，详细信息来自专利WO 2010122089。
T9000 Pyrimorph Antifungal
Pyrimorph 是一种杀真菌剂，对 oomycetes 具有良好抑菌活性。
T8867 RO2959 Hydrochloride RO2959 HCl IL Receptor , Calcium Channel , Interleukin
RO2959 hydrochloride 是选择性CRAC 通道抑制剂，IC50为 402 nM。它是人IL-2产生的有效抑制剂，有效阻断 T 细胞受体触发的基因表达和 T 细胞功能途径。它是由Orai1/Stim1通道介导的钙存储进入的有...
TN1213 2-(Hydroxymethyl)anthraquinone Anti-infection
2-(Hydroxymethyl)anthraquinone 是光可清除保护基团，在结构上可以阻碍性信息素释放。
T2343 AS601245 JNK
AS601245 是 c-Jun NH2-末端激酶 (JNK) 的抑制剂，具有神经保护特性。
T2946 Tanshinone IIA sulfonate sodium Tanshinone IIA sodium sulfonate,Sodium Tanshinone IIA sulfonate,sodium,Tanshinone IIA sulfonate,丹参酮IIA-磺酸钠,丹参酮IIA磺酸盐 P450 , CaMK , Calcium Channel
Tanshinone IIA sulfonate sodium 是从丹参中提取的丹参酮IIA 的水溶性衍生物，是SOCE 抑制剂，用于心血管疾病的研究。
T2170 SKF-96365 hydrochloride SKF96365,1-[2-(4-甲氧基)-2-[3-(4-甲氧基苯基)丙氧基]乙基]咪唑 Apoptosis , Potassium Channel , Calcium Channel , Autophagy , TRP/TRPV Channel
SKF-96365 hydrochloride 是store-operated Ca2+entry 抑制剂，也是TRP channel 阻滞剂。它显著抑制豚鼠离体心脏 hERG、hKCNQ1/hKCNE1、hKir2.1 和 hKv4.3 ...
T6800 CCF642 AC1LYELL Others
CCF642 是蛋白质二硫键异构酶抑制剂(IC50:2.9 μM)。它在多发性骨髓瘤细胞中引起急性内质网应激，并伴随凋亡诱导的钙释放，表现出广泛的抗多发性骨髓瘤作用。
T11217 Eplivanserin 依利色林,SR-46349 5-HT Receptor
Eplivanserin 是一种有效和特异性的 5-HT2A 受体拮抗剂，Kd 值为 1.14 nM，在大鼠皮质膜中 IC50 值为 5.8 nM。
T1198 Tetracaine hydrochloride 盐酸丁卡因,Amethocalne HCl,Amethocaine hydrochloride,Tetracaine HCl Calcium Channel , Sodium Channel
Tetracaine hydrochloride 是一种钙通道蛋白抑制剂，可阻断肌浆网中 Ca2+的电压敏感释放。它主要用作眼科的止痒剂和局部用药，可用于表面和脊髓麻醉。
T6928 Pantoprazole SKF96022,BY1023,泮托拉唑 Autophagy , Proton pump , Apoptosis
Pantoprazole 是一种质子泵抑制剂，用于短期治疗由胃食管反流病引起的食管糜烂和溃疡。它联合阿霉素可显著增加肿瘤生长延迟。它是一种取代的苯并咪唑，是H+/K+-ATPase 抑制剂，可改善 pH 值稳定性，具有抗分泌和抗溃疡的作用。
T0161 Pantoprazole Sodium Hydrate SKF96022 sodium hydrate,SKF96022 (sodium hydrate),泮托拉唑钠水合物,BY1023 (sodium hydrate) Apoptosis , Potassium Channel , Proton pump , Autophagy
Pantoprazole Sodium Hydrate 是一种具有口服活性的质子泵抑制剂。它是取代的苯并咪唑，是H+/K+-ATPase 抑制剂。它可改善 pH 值稳定性，具有抗分泌和抗溃疡的作用。它联合阿霉素可显著增加肿瘤生长延迟。
T23434 GPR35 agonist 2 TC-G 1001 GPR
GPR35 agonist 2 是一种有效的 GPR35 激动剂。GPR35 agonist 2 在 β-arrestin 和 Ca2+ 释放试验中的 EC50 值分别为 26 和 3.2 nM。
T12405 Pentiapine CGS 10746,喷硫平 Dopamine Receptor
Pentiapine 是一种新型的多巴胺释放抑制剂。
Synta66
T13047
synonym:
Target:
5J-4
T24984
synonym:
Target:
YM-58483
T3651
synonym: YM 58483,BTP2
Target:
Zegocractin
TQ0033
synonym: CM4620,N-(5-(6-Chloro-2,2-difluorobenzo[d][1,3]dioxol-5-yl)pyrazin-2-yl)-2-fluoro-6-methylbenzamide,CM-4620
Target:
Allethrin
T25049
synonym:
Target:
CRAC intermediate 2
T10885
synonym:
Target:
CRAC intermediate 1
T10884
synonym: 5-(S)-Fluorowillardiine
Target:
Pyrimorph
T9000
synonym:
Target:
RO2959 Hydrochloride
T8867
synonym: RO2959 HCl
Target:
2-(Hydroxymethyl)anthraquinone
TN1213
synonym:
Target:
AS601245
T2343
synonym:
Target:
Tanshinone IIA sulfonate sodium
T2946
synonym: Tanshinone IIA sodium sulfonate,Sodium Tanshinone IIA sulfonate,sodium,Tanshinone IIA sulfonate,丹参酮IIA-磺酸钠,丹参酮IIA磺酸盐
Target:
SKF-96365 hydrochloride
T2170
synonym: SKF96365,1-[2-(4-甲氧基)-2-[3-(4-甲氧基苯基)丙氧基]乙基]咪唑
Target:
CCF642
T6800
synonym: AC1LYELL
Target:
Eplivanserin
T11217
synonym: 依利色林,SR-46349
Target:
Tetracaine hydrochloride
T1198
synonym: 盐酸丁卡因,Amethocalne HCl,Amethocaine hydrochloride,Tetracaine HCl
Target:
Pantoprazole
T6928
synonym: SKF96022,BY1023,泮托拉唑
Target:
Pantoprazole Sodium Hydrate
T0161
synonym: SKF96022 sodium hydrate,SKF96022 (sodium hydrate),泮托拉唑钠水合物,BY1023 (sodium hydrate)
Target:
GPR35 agonist 2
T23434
synonym: TC-G 1001
Target:
Pentiapine
T12405
synonym: CGS 10746,喷硫平
Target:
1 2 3 4 5 ... 38
CORPORATE
About Us Privacy Notice Events & News Terms & Conditions
SUPPORT
Contact Us Worldwide Distributors Quality Control Technical Support
RESOURCE
Product Catalog Product Citations Signaling Pathways Solution Calculators
FOLLOW OUR
Social Network
Newsletter Subscription
Subscribe to receive our lastest product updates and special offers!
Corporate
Support
Resource
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
Copyright © 2015-2022 TargetMol Chemicals Inc. All rights reserved.