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release

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    1130
    TargetMol | Inhibitors_Agonists
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    TargetMol | Inhibitors_Agonists
Pantoprazole Sodium Hydrate
SKF96022 sodium hydrate, SKF96022 (sodium hydrate), BY1023 (sodium hydrate)
T0161164579-32-2
Pantoprazole Sodium Hydrate (BY1023 (sodium hydrate)) is a proton pump inhibitor drug, used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease.
  • $30
In Stock
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QTY
Tetracaine hydrochloride
Tetracaine HCl, Amethocalne HCl, Amethocaine hydrochloride
T1198136-47-0
Tetracaine hydrochloride (Amethocalne HCl) (Pontocaine), a potent local anaesthetic, is a channel function allosteric inhibitor. It is primarily used as an antipruritic and topically in ophthalmology, and it has been used for surface and spinal anesthesia.
  • $29
In Stock
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QTY
Allethrin
T25049584-79-2
Allethrin induces oxidative stress, apoptosis and calcium release. Allethrin, a pyrethroid insecticide is a major mosquito repellent agent.
  • $30
In Stock
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QTY
Pantoprazole
SKF96022, BY1023
T6928102625-70-7
Pantoprazole (BY1023) is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease.
  • $30
In Stock
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QTY
Eplivanserin
SR-46349
T11217130579-75-8
Eplivanserin (SR-46349) is an effective and selective antagonist of 5-HT2A receptor with a Kd of 1.14 nM and an IC50 value of 5.8 nM in rat cortical membrane.
  • $195
6-8 weeks
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QTY
CCF642
AC1LYELL
T6800346640-08-2
CCF642 (AC1LYELL) is a novel PDI-inhibiting compound with antimyeloma activity.
  • $30
In Stock
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Quercetin
Sophoretin
T2174117-39-5
Quercetin, a flavonoid natural product, is a SIRT1 activator. It is also a PI3K inhibitor, inhibiting PI3Kγ, PI3Kδ, and PI3Kβ with IC50 values of 2.4, 3.0, and 5.4 μM, respectively. Recognized as a heat shock protein inhibitor, Quercetin can significantly reduce exosome release in TII models by downregulating Hsp70 or Hsp90.
  • $42
In Stock
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TargetMol | Inhibitor Hot
Pentiapine
CGS 10746
T1240581382-51-6
Pentiapine (CGS 10746) is a novel inhibitor of dopamine release.
  • $513
In Stock
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TargetMol | Inhibitor Hot
Dirlotapide
Slentrol, CP742033
T15006481658-94-0In house
Dirlotapide (CP742033) is an intestinal selective microsomal triglyceride transfer protein (MTP) inhibitor. It reduces body weight in diabetic dogs.Dirlotapide reduces food intake in a dose-dependent manner, possibly by increasing the release of peptide YY into the circulation.
  • $750
In Stock
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TargetMol | Inhibitor Hot
Amlexanox
CHX3673, Amoxanox, AA673
T163968302-57-8
Amlexanox (AA673) is an anti-aphthous ulcer drug. Amlexanox inhibits the synthesis and release of inflammatory mediators, including leukotrienes and histamine, from mast cells, neutrophils, and mononuclear cells. Amlexanox also acts as a leukotriene D4 antagonist and a phosphodiesterase inhibitor. Amlexanox decreases the time ulcers take to heal as well as the pain associated with the ulcers.
  • $32
In Stock
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TargetMol | Inhibitor Hot
GW4869
GW69A, GW554869A, GW 4869
T36406823-69-4
GW4869 (GW69A) is a selective and non-competitive inhibitor of neutral sphingomyelinase N-SMase (IC50=1 μM). GW4869 also inhibits exosome synthesis release and is commonly used in exosome-related studies.Usually prepared as a suspension for experiments.
  • $67
In Stock
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TargetMol | Inhibitor Hot
Aglafoline
Rocaglamide U, Aglafolin, (-)-Methyl rocaglate
T10260143901-35-3In house
Aglafoline inhibits in a concentration-dependent manner the aggregation and ATP release reaction induced in washed rabbit platelets by PAF (platelet-activating factor). The IC50 values of Aglafoline on PAF (3.6 nM)-induced platelet aggregation were about 50 μM.
  • $2,420
3-6 months
Size
QTY
NMI 8739
n-docosahexaenoyl dopamine, Dha-DA conjugate
T11079129024-87-9In house
NMI 8739 (n-docosahexaenoyl dopamine) is an agonist of D2 autoreceptor. NMI 8739 reduces NO production and elicits concentration-dependent suppression of CCL-20, MCP-1 and IL-6 release.
  • $34
In Stock
Size
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Siguazodan
SKF 94836
T12913115344-47-3In house
Siguazodan (SKF 94836) is an effective, selective, orally active phosphodiesterase III ((PDE-III)) inhibitor with an IC50 of 117 nM. Siguazodan inhibited phenylephrine induced 5-HT release with an IC50 value of 4.2 μM. Siguazodan can increase cAMP accumulation in intact platelets, with EC50 of 18.88 μM.
  • $34
In Stock
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SR-318
T129972413286-32-3In house
SR-318 is a potent and highly selective inhibitor of p38 MAPK, demonstrating IC50 values of 5 nM for p38α, 32 nM for p38β, and 6.11 μM for p38α β. It possesses both anti-cancer and anti-inflammatory activity.
  • $32
In Stock
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UNC10217938A HCl
UNC7938 HCl, UNC10217938A HCl(1347749-97-6 Free base)
T13254L In house
UNC10217938A HCl (UNC7938 HCl) is a 3-deazapteridine analog. UNC10217938A HCl exhibits strong oligonucleotide enhancing effects. UNC10217938A HCl can modulate their intracellular trafficking and release from endosomes, leading to enhance oligonucleotides effects. UNC10217938A HCl also enhances the effects of siRNA and antisense oligonucleotides.
  • $118
In Stock
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TargetMol | Inhibitor Sale
8-Bromo-cGMP sodium
T1406451116-01-9In house
8-Bromo-cGMP sodium is a PKG activator, a membrane-permeable analog of cGMP. 8-Bromo-cGMP sodium has pain-relieving and vasodilatory effects, significantly inhibits Ca2+ macroscopic currents, and inhibits high K+-stimulated insulin release.
  • $36
In Stock
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JNJ-54175446
JNJ-5446
T156221627902-21-9In house
JNJ-54175446 (JNJ-5446) is a CNS-permeable and selective P2X7 receptor antagonist that attenuates the release of IL-1β IL-18 from microglia, and may be used in the study of depression.
  • $293
In Stock
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KP136
AL136
T1566676239-32-2In house
KP136 (AL136) is an orally active anti-allergic compound that inhibits histamine release and is used in studies of asthma and allergic edema.
  • $293 TargetMol
In Stock
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S 18986
T16816175340-20-2In house
S 18986 is a selective, orally active, brain-penetrant positive allosteric modulator of AMPA-type receptors that enhances cognition in rodents by inducing the release of noradrenaline and acetylcholine in the rat hippocampus, subsequently improving object-recognition memory.
  • $30
In Stock
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SAFit2
T168361643125-33-0In house
SAFit2 is a highly potent and selective inhibitor of fk506 binding protein 51 (FKBP51) with a Ki value of 6 nM. SAFit2 can enhance the binding of AKT2-AS160 and participate in the downstream response of glucocorticoid release in vivo. It is a candidate compound for the treatment of obesity, chronic pain, depression and anxiety.
  • $84
In Stock
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Sipatrigine
BW 619C89, 619C89
T16887130800-90-7In house
Sipatrigine (619C89) is an antiepileptic compound with neuroprotective activity through glutamate release, TREK ion channels, TRESK channels, sodium channels, and calcium channel inhibitors in the CNS, and can be used to study TRESK channels.
  • $88 TargetMol
In Stock
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Bunaprolast
U66858
T1719199107-52-5In house
Bunaprolast (U66858) is a novel and potent leukotriene B4 (LTB4) inhibitor.Bunaprolast exhibits oxidative degradation activity and inhibits lipoxygenase and TXB2 release.
  • $700
In Stock
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Cyclic ADP-ribose
cADPR
T19253119340-53-3In house
Cyclic ADP-ribose (cADPR) is an effective calcium mobilization second messenger synthesized from NAD+ by ADP-ribosyl cyclase. It mainly increases cytosolic calcium through Ryanodine receptor-mediated endoplasmic reticulum release and extracellular influx via the opening of TRPM2 channels.
  • $1,083
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