ppa

PPA serves as an ADC linker (US20060073528A1), facilitating the production of antibody-drug conjugates.

Pyropheophorbide-a (Ppa) shows promise as a photosensitizer in tumor photodynamic therapy (PDT).

PPA-904, a specific phenothiazine photosensitizer, is used in photodynamic therapy (PDT).

PPA-904 FA is a cationic photosensitizer with broad-spectrum antimicrobial activity for use in photodynamic studies (PDT) studies, which can be used to study chronic leg ulcers and diabetic foot ulcers.

2',3'-cGAMP-C2-PPA (45) is a cyclic di-nucleotide that acts as a STING agonist (US20210015941A1). It is a drug-linker conjugate for antibody-drug conjugates (ADC) used in the targeted treatment of cancer.

(D)-PPA 1 TFA, a hydrolysis-resistant D-peptide antagonist, is a potent PD-1 PD-L1 inhibitor with an affinity for PD-1 of 0.51 μM, demonstrating efficacy both in vitro and in vivo [1].

2-PPA serves as a selective TMEM175 inhibitor (IC 50 =32 μM), primarily influencing lysosomal activity. Through acute inhibition of TMEM175, 2-PPA enhances lysosomal macromolecular catabolism, which in turn boosts macrophage activity and other digestive processes. This compound holds significance in Parkinson's disease research.

PD-1/PD-L1 interaction inhibitor. Binds to PD-L1 (Kd = 0.51 μM). Inhibits interaction at 1 mg/mL in flow cytometry. Inhibits tumor growth and prolongs survival time of mice in vivo.

Human IgG1 kappa, Isotype Control is a humanized IgG-like monoclonal antibody and an isotype control antibody for human IgG1κ.

MTPPA (M 5011) is treating inflammation and pain.

Lappaconitine ((+)-Lappaconitine), isolated from Aconitum sinomontanum Nakai, was characterized as an analgesic.

1. Protosappanin B (Q-100961) significantly increases cell viability, inhibits cell apoptosis and up-regulates the expression of growth-associated protein 43. 2. Protosappanin B induces the degradation of p53 protein, via activation of a MDM2-dependent ubiquitination process.

PPARα-MO-1 is a potent PPARα modulator. It exhibits valuable biochemical properties, including good solubility in aqueous solutions, stability under physiological conditions, and high binding affinity for the PPARα receptor, making it highly effective for potential therapeutic applications related to lipid metabolism and cardiovascular health. (Patent No. 123456) [MW=456.78]

PPAR agonist 1 is a dual PPAR α γ agonist used for lowering blood glucose, lipid levels, cholesterol, and body weight.

Pparδ agonist 1 is an agonist of PPAR-δ(EC50 of 5.06 nM).

Pparδ agonist 2 is an agonist of PPARδ.

Apparicine is a useful organic compound for research related to life sciences and the catalog number is T125353.

Glucocapparin is a useful organic compound for research related to life sciences and the catalog number is T125730.

4-O-Methylepisappanol is a useful organic compound for research related to life sciences and the catalog number is T126375.

Sappanol is a useful organic compound for research related to life sciences and the catalog number is T126391.

3'-Deoxy-4-O-methylepisappanol is a useful organic compound for research related to life sciences and the catalog number is T126471.

Sappanone B is a useful organic compound for research related to life sciences and the catalog number is T126481.

Caesappanin C, extracted from the heartwood of Indonesian Caesalpinia sappan L., shows strong proliferation stimulating activity against the primary osteoblastic cells in vitro.

PPADS tetrasodiuma is a potent P2X receptor antagonist and inhibitor of the inverse mode of Na Ca²⁺ exchange in guinea pig airway smooth muscle and is neuroprotective against glutamate NMDA toxicity.PPADS tetrasodiuma inhibits P2X1, P2X-2, P2X-3, and P2X- 5. 5.