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Anti-PAPPA Antibody (1X123)
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Catalog No. TMAB-09976
Anti-PAPPA Antibody (1X123) is a Mouse antibody targeting PAPPA. Anti-PAPPA Antibody (1X123) can be used in ELISA,IF,IHC-P,IHC-Fr.
Anti-PAPPA Antibody (1X123)
Anti-PAPPA Antibody (1X123)
Copy Product Info😃Good
Catalog No. TMAB-09976
Anti-PAPPA Antibody (1X123) is a Mouse antibody targeting PAPPA. Anti-PAPPA Antibody (1X123) can be used in ELISA,IF,IHC-P,IHC-Fr.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-PAPPA Antibody (1X123) is a Mouse antibody targeting PAPPA. Anti-PAPPA Antibody (1X123) can be used in ELISA,IF,IHC-P,IHC-Fr. |
| Ig Type | IgG1, k |
| Clone | 1X123 |
| Reactivity | Human (predicted:Mouse,Rat) |
| Verified Activity | Paraformaldehyde-fixed, paraffin embedded Human Placenta; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with PAPPA Monoclonal Antibody, Unconjugated (TMAB-09976) at 1: 200 overnight at 4°C, followed by conjugation to the SP KiT (Mouse) and DAB staining. |
| Application | |
| Recommended Dose | ELISA: 1:30-3000; IF: 1:100-200; IHC-P: 1:100-200; IHC-Fr: 1:100-200 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Secreted. |
| Tissue Specificity | High levels in placenta and pregnancy serum. In placenta, expressed in X cells in septa and anchoring villi, and in syncytiotrophoblasts in the chorionic villi. Lower levels are found in a variety of other tissues including kidney, myometrium, endometrium, ovaries, breast, prostate, bone marrow, colon, fibroblasts and osteoblasts. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Metalloproteinase which specifically cleaves IGFBP-4 and IGFBP-5, resulting in release of bound IGF. Cleavage of IGFBP-4 is dramatically enhanced by the presence of IGF, whereas cleavage of IGFBP-5 is slightly inhibited by the presence of IGF. |
| Immunogen | KLH conjugated synthetic peptide: human PAPPA |
| Antigen Species | Human |
| Gene Name | PAPPA |
| Gene ID | |
| Protein Name | Pappalysin-1 |
| Uniprot ID | |
| Function | Metalloproteinase which specifically cleaves IGFBP-4 and IGFBP-5, resulting in release of bound IGF. Cleavage of IGFBP-4 is dramatically enhanced by the presence of IGF, whereas cleavage of IGFBP-5 is slightly inhibited by the presence of IGF. |
| Molecular Weight | Theoretical: 170 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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