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Synonyms: RELA, p65, NFKB3, NFkappaB p65
Anti-NF-κB p65 Monoclonal Antibody
(4I366)

| Description | Anti-NF-κB p65 Monoclonal Antibody (4I366) is a Mouse antibody targeting NF-κB p65. Anti-NF-κB p65 Monoclonal Antibody (4I366) can be used in WB,IHC. |
| Synonyms | RELA, p65, NFKB3, NFkappaB p65 |
| Ig Type | IgG1 |
| Clone | 4I366 |
| Reactivity | Human,Mouse,Rat,Rabbit,Monkey |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/100-1/500 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The heterodimeric RELA-NFKB1 complex appears to be most abundant one. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human NF-κB p65 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | RELA |
| Gene ID | |
| Protein Name | Transcription factor p65 |
| Uniprot ID |
| Molecular Weight | Theoretical: 65 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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