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Anti-NFKB1 Monoclonal Antibody (6W488)
(Synonyms: p50, p105, NFKB-p50, NFKB-p105, NF-kappa-B, NF-kappaB, NFkappaB, MGC54151, KBF1, EBP-1) Copy Product Info
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Synonyms: p50, p105, NFKB-p50, NFKB-p105, NF-kappa-B, NF-kappaB, NFkappaB, MGC54151, KBF1, EBP-1
Catalog No. TMAT-0894 Copy Product Info
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Anti-NFKB1 Monoclonal Antibody (6W488) is a Mouse antibody targeting NFKB1. Anti-NFKB1 Monoclonal Antibody (6W488) can be used in WB,IHC,IF,FCM.
Anti-NFKB1 Monoclonal Antibody
(6W488)
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| Description | Anti-NFKB1 Monoclonal Antibody (6W488) is a Mouse antibody targeting NFKB1. Anti-NFKB1 Monoclonal Antibody (6W488) can be used in WB,IHC,IF,FCM. |
| Synonyms | p50, p105, NFKB-p50, NFKB-p105, NF-kappa-B, NF-kappaB, NFkappaB, MGC54151, KBF1, EBP-1 |
| Ig Type | IgG2a |
| Clone | 6W488 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human NFKB1 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | NFKB1 |
| Gene ID | |
| Protein Name | Nuclear factor NF-kappa-B p105 subunit |
| Uniprot ID |
| Molecular Weight | Theoretical: 50/105 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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