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By Target- Apoptosis
- CETP(1)
- Hedgehog/Smoothened(1)
- Others(1)
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Results for "
24-dhcr
" in TargetMol Product Catalog- Inhibitors & Agonists2
Triparanol
NSC-65345, NSC65345, NSC 65345, MER-29
T2629678-41-1In house
Triparanol (NSC-65345) interferes with posttranslational modification of Hedgehog signaling molecules as well as the sterol sensing domain of its receptor PTCH1, leading to down-regulation of Hedgehog signaling. Triparanol suppresses human tumor growth and is an antilipemic agent with high ophthalmic toxicity.
- $298
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QTY
Azacosterol hydrochloride
T711331249-84-9
Azacosterol is a diaza derivative of cholesterol which acts as a hypocholesteremic agent by blocking delta-24-reductase causing accumulation of desmosterol. Azacosterol acts as an inhibitor of 24-dehydrocholesterol reductase (24-DHCR), preventing the formation of cholesterol from desmosterol. Although it primarily acts to inhibit 24-DHCR, the drug also inhibits other steps in cholesterol biosynthesis. The antifertility effects of the drug in birds are mediated by inhibition of steroid hormone production, steroid hormones being synthesized from cholesterol.
- $1,520
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QTY
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