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Results for "

24(s)hydroxy cholesterol

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    1055
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    54
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    TargetMol | Inhibitors_Agonists
24(S)-hydroxy Cholesterol
Cerebrosterol, 24S-OHC, 24S-HC
T21562474-73-7
24(S)-hydroxy Cholesterol (24S-OHC) is the terminal product of the cholesterol elimination pathway in neural tissues. It is an LXR agonist and a selective positive allosteric modulator of NMDARs. It can serve as a biomarker for NPD, induce cognitive decline in mice, and is useful for studying neurological diseases.
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    Rotenone
    Rotocide, Rotenon, Paraderil, Dactinol, Barbasco
    T297083-79-4
    Rotenone (Rotocide) is a natural product and a botanical insecticide. Rotenone is a mitochondrial electron transport complex I inhibitor that promotes the production of reactive oxygen species in mitochondria and induces apoptosis.
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    Rutin
    Rutoside, Quercetin 3-O-rutinoside
    T0795153-18-4
    Rutin (Quercetin 3-O-rutinoside), a flavonoid, has a variety of biological activities including antiallergic, anti-inflammatory, antiproliferative, and anticarcinogenic properties.
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    TargetMol | Inhibitor Hot
    Astragaloside IV
    AST-IV, AS-IV
    T297384687-43-4
    Astragaloside IV (AS-IV), an active component isolated from Astragalus membranaceus, suppresses the activation of ERK1 2 and JNK, and downregulates matrix metalloproteases (MMP)-2, (MMP)-9 in MDA-MB-231 breast cancer cells. Astragaloside IV is a bioactive saponin first isolated from the dried plant roots of the genus Astragalus, which is used in traditional Chinese medicine.1 It dose-dependently inhibits human adenovirus type 3 (HAdV-3) in A549 cells (IC50 = 23 μM; LC50 = 865 μM).It inhibits replication of HAdV-3 and decreases HAdV-3-induced apoptosis. It has diverse protective effects for the cardiovascular, immune, digestive, and nervous systems. In particular, it reduces myocardial infarct size in dogs when administered prior to coronary ligation and reduces reperfusion arrhythmias in isolated rat hearts.
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    TargetMol | Inhibitor Hot
    Bleomycin Sulfate
    NSC125066, Blenoxane
    T61169041-93-4
    Bleomycin Sulfate (Blenoxane) is a glycopeptide antibiotic, an inhibitor of DNA synthesis. Bleomycin Sulfate causes DNA strand breaks but not RNA strand breaks. Bleomycin Sulfate has antitumor activity.
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    TargetMol | Inhibitor Hot
    sterculic acid
    T41253738-87-4In house
    Sterculic acid, a stearoyl-CoA desaturase-1 (SCD1) inhibitor, effectively suppresses delta-9 desaturase (Δ9D) activity in a dose-dependent manner, exhibiting an inhibition concentration (IC50) value of 0.9 μM [1].
    • Inquiry Price
    6-8 weeks
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    Moracin C
    TN194969120-06-5In house
    Moracin C, a natural compound found in Morus mesozygia, Morus alba var. multicaulis, is an anti-inflammatory agent. moracin C inhibits nitric oxide (NO) release and LPS-activated reactive oxygen species (ROS) in cells.
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    8-10 weeks
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    1-Methoxycarbonyl-β-carboline
    1-Methoxycarbonyl-beta-carboline
    TN25493464-66-2In house
    1-Methoxycarbonyl-β-carboline (1-Methoxycarbonyl-beta-carboline) is an alkaloid from Ailanthus altissima.
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    Cepharanthine
    NSC-623442
    T0131481-49-2
    Cepharanthine (NSC-623442) is a natural alkaloid that inhibits TNF-α-mediated NFκB stimulation, plasma membrane lipid peroxidation, and platelet aggregation, as well as cytokine production. Cepharanthine exhibits anti-inflammatory, antioxidant, and antitumor activities.
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    Mequinol
    4-Hydroxyanisole, Leucobasal, 4-Methoxyphenol
    T0501150-76-5
    Mequinol (Leucobasal) is a synthetic derivate of hydroquinone and depigmenting agent. Although the exact mechanism of the depigmenting effects of mequinol remains unclear, it may exert its effect by oxidation of tyrosinase to cytotoxic products in melanocytes.
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    γ-Aminobutyric acid
    Piperidic acid, Gamma-aminobutyric acid, 4-Aminobutyric acid, 4-Aminobutanoic acid
    T050856-12-2
    γ-Aminobutyric acid (4-Aminobutyric acid) is the predominant inhibitory neurotransmitter in the central nervous system.
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    D-Arabinopyranose
    D-arabinose, D(-)-Arabinose
    T058828697-53-2
    D-(-)-Arabinose is a reducing sugar useful as a substrate in analysis of arabinose isomerases and synthesis of D-erythroascorbic acid in yeast. It shows strong growth inhibition against the Caenorhabditis elegans with an IC50 of 7.5 mM.
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    D-Galactose
    D-Galactopyranose, D-(+)-Galactose, Alpha-D-galactose
    T059159-23-4
    D-Galactose (Alpha-D-galactose) is an aldohexose that exists naturally in the D-form in lactose, cerebrosides, gangliosides, and mucoproteins and is converted enzymatically into D-glucose for metabolism or polysaccharides for storage. It accelerates senescence in invertebrates and mammals and has been used as a model for aging.
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    Ursolic acid
    Urson, Prunol, NSC-4060, NSC 167406, Malol
    T072277-52-1
    Ursolic acid (Prunol) is a natural product, a pentacyclic triterpene carboxylic acid extracted from Rhododendron caprifolium. Ursolic acid has anti-tumor, anti-inflammatory, anti-bacterial and hypoglycemic activities.
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    Benzyl benzoate
    Scabitox, Novoscabin, Benzoic acid benzyl ester, Ascabiol
    T0729120-51-4
    Benzyl benzoate (Benzoic acid benzyl ester) is one of the older preparations used for the therapy of scabies. Scabies is a skin infection caused by the Sarcoptes scabiei. Its symptoms are red spots, severe itching (particularly at night), and may lead to a secondary infection. Benzyl benzoate is useful in the therapy of scabies because it is lethal to this mite. It is also used for the therapy of lice affection of the body and head. Benzyl benzoate is not the therapy of choice for scabies because of its irritant properties.
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    Tannic acid
    Gallotannic acid
    T08011401-55-4
    Tannic acid (Gallotannic acid) is a novel hERG channel blocker.
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    D-Glucose
    Grape sugar, Glucopyranose, Dextrose, D(+)-Glucose
    T088750-99-7
    D-Glucose (Glucopyranose) is a monosaccharide, a natural glucose, a sweetener. D-Glucose is the main functional substance of living organisms, and is used as a nutrient in medicine, with diuretic, detoxification and cardiotonic effects.
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    L-Ascorbic acid
    Vitamin C, L-Ascorbate, L(+)-Ascorbic acid, Ascorbic acid
    T092850-81-7
    L-Ascorbic acid (Vitamin C) is a natural product that is a potent reducing agent and antioxidant. L-Ascorbic acid functions in fighting bacterial infections, in detoxifying reactions, and in the formation of collagen. L-Ascorbic acid is used in the treatment of scurvy.
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    Docetaxel
    RP-56976, NSC 628503
    T1034114977-28-5
    Docetaxel (RP-56976), a semi-synthetic analog of paclitaxel, is a microtubule depolymerization inhibitor (IC50=0.2 μM) that attenuates the effects of bcl-2 and bcl-xL gene expression and exhibits apoptosis-inducing, anti-tumor activity.
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    Vitamin B12
    Cyanocobalamin
    T104068-19-9
    Cyanocobalamin is a cobalt-containing coordination compound generated by intestinal microbes and a natural water-soluble vitamin of the B-complex family that must combine with Intrinsic Factor for absorption by the intestine. Cyanocobalamin is necessary for hematopoiesis, neural metabolism, DNA, and RNA production, and carbohydrate, fat, and protein metabolism. B12 improves iron functions in the metabolic cycle and assists folic acid in choline synthesis. B12 metabolism is interconnected with that of folic acid. Vitamin B12 (Cobalamin) deficiency causes pernicious anemia, megaloblastic anemia, and neurologic lesions.
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    Biotin
    Vitamin H, Vitamin B7, D-Biotin
    T111658-85-5
    Biotin (Vitamin H) is a water-soluble B-vitamin and is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids.
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    DL-Mevalonolactone
    Mevalonolactone
    T1353674-26-0
    DL-Mevalonolactone, a human endogenous metabolite, is the δ-lactone form of mevalonate, a precursor of the mevalonate pathway. It reduces mitochondrial membrane potential (∆Ψm), Ca2+ retention and NAD(P)H levels in the brain, and also induces mitochondrial swelling.DL-Mevalonolactone induces inflammation and oxidative stress, and reduces mitochondrial membrane potential.
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    Hexadecanal
    Palmitaldehyde
    T13719629-80-1
    Hexadecanal (Palmitaldehyde) is a free fatty aldehyde found in animals.
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    7-10 days
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    L-Xylose
    L-(-)-Xylose
    T15700609-06-3
    L-Xylose (L-(-)-Xylose), a levo-isomer of Xylose, is classified as an aldopentose-type monosaccharide.
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