phosphate

Sphingosine-1-phosphate (S1P) is an agonist for S1P1-5 receptors and a ligand for GPR3, GPR6, and GPR12. As an intracellular second messenger, it mobilizes Ca2+ and acts as an extracellular ligand for G-protein coupled receptors. This important lipid mediator is generated from sphingosine or other membrane phospholipids.

Quercetin-3'-o-phosphate TEA (Quercetin 3'-phosphate TEA) is an adenosine A receptor antagonist that can be used to prevent and treat metabolic disorders.

Sodium 4-nitrophenyl phosphate hexahydrate (4-Nitrophenyl phosphate disodium hexahydrate) is hydrolyzed by alcohol phosphatase (ALP) and can be used to develop a dual-mode immunoassay for the detection of ochratoxin A (OTA).

Povorcitinib phosphate is a selective JAK1 inhibitor and can be used in studies about the treatment of cutaneous lupus erythematosus and Lichen planus.

1,2-Dipalmitoyl-sn-glycerol 3-phosphate (a phosphatidic acid) is a human endogenous metabolite.

BI 653048 phosphate is a selective, orally active agonist of nonsteroidal glucocorticoid (GC) with an IC50 of 55 nM.

Ens-163 phosphate is a muscarinic M1 receptor agonist. It is selective.

Uzansertib phosphate (INCB053914 phosphate) is an orally active, ATP-competitive inhibitor of pan-PIM kinase(PIM1, PIM2, PIM3 with IC50s of 0.24 nM, 30 nM, 0.12 nM , respectively).

S-8510 phosphate is an agonist of inverse Benzodiazepine (BDZ) receptor(Kis of 34.6 nM, 36.2 nM for –GABA and +GABA respectively).

AICAR phosphate (Acadesine phosphate) is an AMPK activator and inhibitor of autophagy, YAP, and mitophagy. It serves as an adenosine analog, regulating glucose and lipid metabolism, and inhibiting the production of pro-inflammatory cytokines and iNOS.

D-Sedoheptulose 7-phosphate is a common precursor of heptaic acid (group III) and the heptasaccharide of hygromycin B (group IV). This compound can be converted to NDP-heptose via similar biosynthetic pathways present in these substances.

Galactose 1-phosphate, an intermediate substance in both galactose metabolism and nucleotide sugar processes, plays a crucial role in the biochemical pathways involved.

Tricresyl phosphate is an organophosphate compound. It is used as a plasticizer and diverse other applications.

Triethyl phosphate is a chemical compound. It can be called "phosphoric acid, triethyl ester".

2-Ethylhexyl diphenyl phosphate is an organophosphorus flame retardant (OPFRs) and acts as a PPARG agonist (EC20: 2.04 µM). Additionally, it inhibits the transcriptional activity of ERRγ (IC50: 1.3 µM) and enhances the expression of 3β-HSD1, human chorionic gonadotropin (hCG), and progesterone secretion. This compound is applicable in studies related to female reproduction and fetal development.

Diphenyl cresyl phosphate is a flame retardant, plasticizers, additives of gasoline, and lubricant.

Antazoline phosphate is an antihistamine with anticholinergic properties. Antazoline prevents the typical allergic symptoms on capillaries, mucous membranes, skin, and gastrointestinal and bronchial smooth muscles by antagonizing the histamine H1 receptor

7-Deazaadenosine 5'-phosphate (Tubercidin 5'-phosphate; 7-Deaza-AMP) is a potential substrate and competitive inhibitor of enzymes that interact with 5′-adenosine monophosphate. As a nucleotide derivative, 7-Deazaadenosine 5'-phosphate modulates cellular functions by influencing intracellular signaling pathways, particularly those involving AMP.

Adenosine-5'-O-diphosphoribose phosphate sodium is a structural analog of NADPH and acts as an HMG-CoA reductase inhibitor. It inhibits microsomal HMG-CoA reductase with an apparent Ki value of 550 μM at low thiol concentrations.

Disopyramide, a sodium channel blocker in the Class of 1a anti-arrhythmic agent, is used in the treatment of Ventricular Tachycardia. Disopyramide has a negative inotropic effect on the ventricular myocardium, resulting in a significant decrease in contra

Dexamethasone phosphate is a synthetic adrenal corticosteroid. It also has potent anti-inflammatory properties.

KN-93 (Phosphate) can competitively block the binding of calmodulin to the corresponding kinase. It is a calcium/calmodulin-dependent kinase II (CaMKII) inhibitor with a Ki of 370 nM. It can also inhibit the proliferation of human hepatic stellate cells.

Ganaplacide phosphate exerts multi-stage antimalarial activity against Plasmodium symptomatic asexual blood-stage infections, and is able to prevent transmission and block infection in animal models.

Osilodrostat phosphate is a potent oral 11β-hydroxylase inhibitor.