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Efzimfotase alfa
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Catalog No. T9901A-984Cas No. 2746354-58-3
Alias ALXN-1850
Efzimfotase alfa is an enzyme replacement therapy targeting tissue non-specific alkaline phosphatase (TNSALP) deficiency. By hydrolyzing substrates of TNSALP, Efzimfotase alfa reduces concentrations of substrates such as inorganic pyrophosphate (PPi) and pyridoxal 5'-phosphate (PLP). It is being investigated for its potential use in hypophosphatasia (HPP).
Efzimfotase alfa
Efzimfotase alfa
😃Good
Catalog No. T9901A-984Alias ALXN-1850Cas No. 2746354-58-3
Efzimfotase alfa is an enzyme replacement therapy targeting tissue non-specific alkaline phosphatase (TNSALP) deficiency. By hydrolyzing substrates of TNSALP, Efzimfotase alfa reduces concentrations of substrates such as inorganic pyrophosphate (PPi) and pyridoxal 5'-phosphate (PLP). It is being investigated for its potential use in hypophosphatasia (HPP).
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | Inquiry | Inquiry | Inquiry | |
| 5 mg | Inquiry | Inquiry | Inquiry |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Efzimfotase alfa is an enzyme replacement therapy targeting tissue non-specific alkaline phosphatase (TNSALP) deficiency. By hydrolyzing substrates of TNSALP, Efzimfotase alfa reduces concentrations of substrates such as inorganic pyrophosphate (PPi) and pyridoxal 5'-phosphate (PLP). It is being investigated for its potential use in hypophosphatasia (HPP). |
| Synonyms | ALXN-1850 |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | ＜ 1.0 EU/mg |
| Conjucates | Unconjugated |
| Target | TNSALP |
| Cas No. | 2746354-58-3 |
Storage & Solubility Information
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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