fp

FP0429 is an agonist of mGlu4.

Notoginsenoside FP2 is a natural product isolated from the fruit pedicels of Panax notoginseng and can be used in studies about the treatment of cardiovascular diseases.

Latanoprost acid is a selective agonist of prostanoid receptors and inhibits RANKL-induced osteoclastogenesis and function through the inhibition of c-fos/NFATc1 pathway. Latanoprost acid can be used in studies about lowering pressure inside the eyes.

Sulfentrazone (FP-846) is purified form of sulfentrazone which acts as a protoporphyrinogen oxidase inhibitor.It is a phenyl triazolinone herbicide

L 888607 is an effective and selective CRTH2 agonist (Ki: 0.8 nM).

GJN75561 is a VMAT2 imaging agent.

Bimatoprost acid (17-phenyl trinor PGF2α) is a metabolically stable analog of PGF2α and has a potential antagonistic activity for the FP receptor. It has a relative potency of 756% compared to PGF2α for binding to the FP receptor on ovine luteal cells.

Linvemastat (Compound FC-4) is an orally active MMP-12 inhibitor with an IC50 of less than 10 nM and demonstrates high selectivity over MMP-1, -2, -3, -7, -9, -10, and -14. It significantly reduces lung fibrosis in a mouse model of bleomycin-induced unilateral pulmonary fibrosis and effectively alleviates kidney damage, interstitial inflammation, or fibrosis in a unilateral ureteral obstruction renal fibrosis model. Linvemastat is suitable for research into inflammatory diseases such as idiopathic pulmonary fibrosis (IPF), inflammatory bowel disease (IBD), and asthma.

Latanoprost (Xalatan) is a prostaglandin F2alpha analogue and a prostanoid selective FP receptor agonist with an ocular hypertensive effect.

Bexmarilimab (FP-1305) is a highly potent, humanized anti-CLEVER-1 IgG4 antibody with an IC50 value of 4.51 nM, promoting immune conversion of tumor-associated macrophage phenotype M2 to M1, and can be used to study cancer.

Aderamastat (FP-025) is an orally active matrix metalloproteinase 12 (MMP-12) inhibitor used for research in allergic asthma, COPD, and pulmonary fibrosis.

Acetyl-6-formylpterin (Ac-6-FP) serves as a hapten that forms a covalent bond with MR1 via the Lys43 residue, which leads to the upregulation of the protein. This compound is employed in research related to inflammation [1].

FP-18 disodium is a TLR-4 agonist and acts as a vaccine adjuvant.

FP-20 sodium is a selective TLR4 agonist and serves as a vaccine adjuvant. It induces MAPK and NLRP3-dependent inflammasome activation. In experiments with mouse OVA antigen vaccination, FP-20 sodium showed no toxicity and facilitated IgG production.

FP-21399, an HIV fusion inhibitor, is used potentially for the treatment of HIV infection.

FP-biotin is a potent organophosphorus toxicant ideal for identifying novel biomarkers of organophosphorus exposure. It measures FAAH, ABHD6, and MAG-lipase activity specifically in plasma studies, thanks to the efficient purification of biotinylated peptides through binding to immobilized avidin beads.

FP20Rha is a potent TLR4 agonist that enhances the efficacy of vaccines against Pseudomonas aeruginosa.

α-Rhamnosyl FP20 sodium functions as a TLR-4 agonist and serves as a vaccine adjuvant.

α-Galactosyl FP20 sodium acts as a TLR-4 agonist and functions as a vaccine adjuvant.

α-Glucosyl FP20 sodium is a TLR-4 agonist and serves as a vaccine adjuvant.

FP802 is a potent oral TwinF interface inhibitor capable of disrupting and neutralizing the toxicity of the NMDAR/TRPM4 death complex. Within the 5xFAD Alzheimer's disease (AD) mouse model, FP802 demonstrates significant neuroprotective effects, preventing cognitive decline, preserving neuronal structural integrity, reducing β-amyloid plaque formation, and mitigating mitochondrial damage. In the amyotrophic lateral sclerosis (ALS) mouse model, FP802 prevents motor neuron loss, lowers serum neurofilament light chain (NfL) levels, improves motor performance, and extends the lifespan of mice. FP802 can be utilized for research related to Alzheimer's disease and amyotrophic lateral sclerosis [1][2].

Notoginsenoside FP1 (Standard) is a reference standard for research and analysis in studies involving Notoginsenoside FP1. Notoginsenoside FP1 is a natural product that can be used in related research in the field of life sciences. Its product number is TN8463.

Notoginsenoside FP2 (Standard) is a reference standard for research and analysis in studies involving Notoginsenoside FP2. Notoginsenoside FP2 is a natural product isolated from the fruit pedicels of Panax notoginseng and can be used in studies about the treatment of cardiovascular diseases.

Notoginsenoside FP1 is a natural product that can be used in related research in the field of life sciences. Its product number is TN8463.