atr — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T10406	Tuvusertib	M1774,ATR inhibitor 1	Apoptosis , ATM/ATR , Others , Chk
	Tuvusertib (M1774) is an orally available ataxia telangiectasia and Rad3-related (ATR) kinase inhibitor (Ki< 1 µΜ) with selective and potentially antitumor activity.Tuvusertib selectively inhibits ATR activity and blocks...		Apoptosis , ATM/ATR , Others , Chk
T3032	VE-821	ATR Inhibitor IV	ATM/ATR
	VE-821 (ATR Inhibitor IV) is a selective ATP competitive inhibitor of ATR( Ki/IC50: 13/26 nM in cell-free assays).		ATM/ATR
T62083	Camonsertib	ATR inhibitor 4,RP-3500	ATM/ATR
	Camonsertib (RP-3500) is a selective, orally active ATR kinase inhibitor (ATRi) with an IC50: 1.00 nM in biochemical assays and exhibits potent antitumour effects. Camonsertib is 30 times more selective for ATR than mTOR...		ATM/ATR
T40077	ATR-IN-9
	ATR-IN-9 is a highly effective inhibitor of Ataxia-telangiectasia and RAD-3-related protein kinase (ATR). With an IC50 value as low as 10 nM, ATR-IN-9 demonstrates exceptional potency.
T40212	ATR-IN-4
	ATR-IN-4, a potent inhibitor of ATR (Ataxia telangiectasia mutated gene Rad 3-associated kinase), restricts the growth of DU145 prostate cancer cells and NCI-H460 lung cancer cells, with IC 50 values of 130.9 nM and 41.3...
T9321	Zapnometinib	ATR-002,3,4-difluoro-2-(2-chloro-4-iodophenylaMino)-benzoic acid,PD0184264,2-(2-chloro-4-iodoanilino)-3,4-difluorobenzoic acid	Influenza Virus , MEK , Antibacterial
	Zapnometinib (ATR-002) is a MEK inhibitor.		Influenza Virus , MEK , Antibacterial
T62035	ATR-IN-7
	ATR-IN-7 is a potent inhibitor of ATR.
T61636	ATR-IN-19
	ATR-IN-19 (Compound 15 R-configure) is an ATR inhibitor [1].
T63555	ATR-IN-6
	ATR-IN-6 is a potent inhibitor of ATR. ATR is a protein kinase that is involved in genome stability and DNA damage repair and is a member of the PIKK family. aTR-IN-6 has shown potential for ATR kinase-mediated diseases ...
T62651	ATR-IN-11
	ATR-IN-11 (Compound Hit01) is a potent inhibitor of ataxia capillaris and Rad3-related (ATR) kinases. ATR-IN-11 is a promising lead compound for the discovery of subsequent drugs targeting the ATR kinase, a key regulator...
T61587	ATR-IN-15
	ATR-IN-15 (compound 1) is a highly potent and orally active inhibitor of ATR kinase with an IC50 of 8 nM. Additionally, ATR-IN-15 demonstrates inhibitory activity against several targets, including human colon tumor cell...
T79058	ATR-IN-24		ATM/ATR
	ATR-IN-24 (Compound 1) is an ATR inhibitor with demonstrated anticancer activity [1].		ATM/ATR
T63923	ATR-IN-5
	ATR-IN-5 is a potent inhibitor of ATR, a member of the PIKK family of proteins involved in genome stability and DNA damage repair. ATR is a member of the PIKK family, a class of protein kinases involved in genome stabili...
T62233	ATR-IN-10
	ATR-IN-10 is a potent and highly selective inhibitor of ATR kinase (IC50: 2.978 μM).
T62548	ATR-IN-17
	ATR-IN-17 is a potent inhibitor of ATR kinase with good anti-cancer effects in LoVo cells (IC50: 1 nM).
T61432	ATR-IN-16
	ATR-IN-16 (compound 46) is a highly effective ATR kinase inhibitor, exhibiting considerable anticancer activity in LoVo cells, as demonstrated by its IC 50 value of 410 nM [1].
T79121	ATR-IN-29		ATM/ATR
	ATR-IN-29, a potent, orally active inhibitor of ATR kinase, exhibits an IC50 of 1 nM and demonstrates antiproliferative activity [1].		ATM/ATR
T79031	ATR-IN-21		ATM/ATR
	ATR-IN-21, also known as compound 60, is a potent inhibitor of ATR, exhibiting an IC50 of less than 1000 nM [1].		ATM/ATR
T63604	ATR-IN-18
	ATR-IN-18 is an orally active ATR kinase inhibitor (IC50: 0.69 nM). aTR-IN-18 exhibited anti-proliferative effects in LoVo cells (IC50: 37.34 nM). aTR-IN-18 showed anti-tumor effects.
T62084	ATR-IN-8
	ATR-IN-8 is a potent inhibitor of ATR. ATR-IN-8 has shown potential research value in cancer diseases.