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Results for "

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  • Inhibitors & Agonists
    1099
    TargetMol | All_Pathways
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    TargetMol | Compound_Libraries
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Adrenosterone
Reichstein's substance G, 11-oxoandrostenedione, 11-ketoandrostenedione
T2207382-45-6
Adrenosterone (11-ketoandrostenedione) is a steroid hormone isolated from the adrenal cortex.
  • $35
In Stock
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(-)-Hydroxycitric acid lactone
Garcinia lactone
T1204527750-13-6
(-)-Hydroxycitric acid lactone (Garcinia lactone) is an anti-obesity agent and a potent inhibitor of ATP citrate lyase, an enzyme that catalyzes the extramitochondrial cleavage of citrate to oxaloacetate and acetyl-CoA.
  • $64
In Stock
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SBC-110736
SBC110736
T45241629166-02-4
SBC-110736 is an inhibitor of proprotein convertase subtilisin kexin type 9 (PCSK9).
  • $34
In Stock
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CB1 antagonist 4
T85111253641-65-4
CB1 antagonist 4 is an antagonist of cannabinoid receptor type 1 (CB1), with potential for the treatment of obesity and type 2 diabetes.
  • $41
In Stock
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TargetMol | Citations Cited
FTO-IN-1
UUN44923
T90892243944-92-3
UUN44923 is a FTO inhibitor. It may be useful for treating diseases assocd. with FTO targets, obesity, metabolic syndrome (MS) , type 2 diabetes (T2D) , Alzheimer's diseases, breast cancers, small- cell lung cancers, a human bone marrow striated muscle cancer, a pancreatic cancer, malignant glioblastoma and the like.
  • $78
In Stock
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Tormentic acid
TN111813850-16-3
Tormentic acid is a natural product. It has anticancer, anti-inflammatory, anti-atherogenic , anti-allodynic, and hepatoprotective properties,
  • $68
In Stock
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Valproic Acid
VPA, Sodium valproate, Depakine, 2-Propylvaleric Acid, 2-Propylpentanoic Acid
T706499-66-1
Valproic Acid (2-Propylpentanoic Acid) is an HDAC inhibitor that suppresses HDAC1 activity and induces HDAC2 degradation, exhibiting oral bioavailability. Valproic Acid activates Notch1 signalling and inhibits the proliferation of small cell lung carcinoma cells, making it applicable for research into epilepsy and bipolar disorder.
  • $50
In Stock
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TargetMol | Inhibitor Hot
TargetMol | Citations Cited
Valproic acid sodium salt
Sodium Valproate
T16021069-66-5
Valproic acid sodium salt (Sodium Valproate) is the sodium salt form of valproic acid with anti-epileptic activity. Valproic acid sodium salt is converted into its active form, valproate ion, in blood. Although the mechanism of action remains to be elucidated, Valproic acid sodium salt increases concentrations of gamma-aminobutyric acid (GABA) in the brain, probably due to inhibition of the enzymes responsible for the catabolism of GABA. This potentiates the synaptic actions of GABA. Valproic acid sodium salt may also affect potassium channels, thereby creating a direct membrane-stabilizing effect.
  • $42
In Stock
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TargetMol | Citations Cited
Cetilistat
ATL-962
T3283282526-98-1
Cetilistat (ATL-962) is a novel inhibitor of pancreatic lipase being developed by Alizyme for the treatment of obesity and associated co-morbidities, including type 2 diabetes.
  • $29
In Stock
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Divalproex Sodium
Valproate semisodium, Epival
T647476584-70-8
Divalproex Sodium (Valproate semisodium) binds to and inhibits gamma-aminobutyric acid (GABA) transaminase and its anticonvulsant activity may be exerted by increasing brain concentration of GABA and by inhibiting enzymes that catabolize GABA or block the reuptake of GABA into glia and nerve endings. It also is an HDAC inhibitor, Comprised of sodium valproate and valproic acid with anticonvulsant and antiepileptic activities. Divalproex may also work by suppressing repetitive neuronal firing through the inhibition of voltage-sensitive sodium channels.
  • $33
In Stock
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Cholinehy droxide
T8734123-41-1
Choline hydroxide is a ubiquitous water soluble nutrient, often associated with the B vitamins
  • $29
In Stock
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TargetMol | Citations Cited
Meclofenamic acid
Meclofenamate
T11990644-62-2
Meclofenamic acid (Meclofenamate) is a non-selective gap-junction blocker and a selective inhibitor of the fat mass and obesity-associated (FTO) enzyme, with notable anti-inflammatory activities.
  • $81
In Stock
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Neomangiferin
Mangiferin 7-glucoside
T380464809-67-2
Neomangiferin (Mangiferin 7-glucoside) has beneficial effects on high fat diet-induced nonalcoholic fatty liver disease in rats. Neomangiferin and mangiferin inhibit tartrate-resistant acid phosphatase, a biochemical marker of osteoclast function and bone resorption.
  • $30
In Stock
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Fat Soluble Vitamins Mix-3 In Ethanol(0.1%Bht) (Standard)
TMSM-3949
Fat Soluble Vitamins Mix-3 In Ethanol(0.1%Bht) (Standard) is a reference standard of Fat Soluble Vitamins Mix-3 In Ethanol(0.1%Bht) intended for quantitative analysis, quality control, and related biochemical research applications.
  • $1,530
7-10 days
Size
QTY
Mix-8 Fat-Solublevitamins In Methanol With 0.4%Bht+0.4%Vc (Standard)
TMSM-3951
Mix-8 Fat-Solublevitamins In Methanol With 0.4%Bht+0.4%Vc (Standard) is a reference standard of Mix-8 Fat-Solublevitamins In Methanol With 0.4%Bht+0.4%Vc intended for quantitative analysis, quality control, and related biochemical research applications.
  • $2,300
7-10 days
Size
QTY
Ceftolozane sulfate
FR-264205, FR264205, FR 264205, CXA-101 sulfate, CXA101 sulfate
T30790936111-69-2
Ceftolozane sulfate (FR-264205) is a cephalosporin antibiotic with broad-spectrum antimicrobial activity, inhibits P. aeruginosa PAO1, inhibits Pseudomonas aeruginosa, and is used in the study of pneumonia.
  • $456
In Stock
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TargetMol | Inhibitor Hot
Bleomycin Sulfate
NSC125066, Blenoxane
T61169041-93-4
Bleomycin sulfate is a glycopeptide antibiotic with antitumor activity. It is commonly used as a DNA-damaging agent and DNA synthesis inhibitor. It functions by inducing DNA strand breaks without affecting RNA strands. Bleomycin sulfate is widely used in cancer research and for establishing pulmonary fibrosis animal models.
  • $37
In Stock
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TargetMol | Inhibitor Hot
TargetMol | Citations Cited
G-418 disulfate
Geneticin sulfate, Geneticin, G418 Sulfate, Antibiotic G-418 sulfate
T6512108321-42-2
G-418 disulfate (Geneticin sulfate) is an aminoglycoside antibiotic that selectively inhibits eukaryotic protein synthesis by blocking peptide chain elongation.
  • $30
In Stock
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TargetMol | Inhibitor Hot
TargetMol | Citations Cited
Leupeptin Hemisulfate
T6564103476-89-7
Leupeptin hemisulfate is a protease inhibitor with cell membrane-permeable, reversible, competitive, and oral activities. Leupeptin hemisulfate inhibits the activity of Cathepsin B, Cathepsin H, and Cathepsin L, and blocks fusion of amphipathic lysosomes. Leupeptin hemisulfate also has anti-inflammatory activity.
  • $47
In Stock
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TargetMol | Inhibitor Hot
TargetMol | Citations Cited
GC7 Sulfate
T11372150417-90-6In house
GC7 Sulfate is a potent inhibitor of deoxyhypusine synthase (DHS). Eukaryotic translation initiation factor 5A2 (eIF5A2) is the only known substrate for DHS, so GC7 inhibits the activation of eIF5A2 by inhibiting DHS activity.
  • $47
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Penbutolol sulfate
(-)-Terbuclomine
T1240238363-32-5In house
Penbutolol sulfate ((-)-Terbuclomine) binds to both β2-adrenergic and β1-adrenergic receptors, making it a non-selective β-blocker.
  • $35
In Stock
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MEG hemisulfate
Mercaptoethylguanidine hemisulfate
T219673979-00-8In house
MEG hemisulfate (Mercaptoethylguanidine hemisulfate) acts as a highly potent and selective suppressor of inducible NO synthase (iNOS), demonstrating EC50 values of 11.5 μM for iNOS, 110 μM for ecNOS, and 60 μM for bNOS in tissue homogenates. It is notably effective as a peroxynitrite scavenger and blocks peroxynitrite-triggered oxidative mechanisms. Furthermore, this compound offers protective benefits across various experimental inflammation prototypes, such as ischemia/reperfusion injury, hemorrhagic shock, periodontitis, inflammatory bowel disease, and both endotoxic and septic shock.
  • $30
In Stock
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Efegatran sulfate
LY-294468 sulfate, LY294468 sulfate, LY 294468 sulfate, GYKI-14766 sulfate
T25364L126721-07-1In house
Efegatran sulfate (LY294468 sulfate) is a potent thrombin inhibitor used in the treatment of thrombotic disorders.
  • $323
In Stock
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Lipoxamycin hemisulfate
U-26146D, U26146D, U 26146D, Lipoxamycin, sulfate (2:1), Lipoxamycin
T2630811075-87-9In house
Lipoxamycin hemisulfate (Lipoxamycin) is an inhibitor of serine palmitoyltransferase (IC50 = 21 nM) with antifungal activity.
  • $50
In Stock
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