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Anti-GNS Antibody (8V673)
😃Good
Catalog No. TMAY-00605
Alias N-Acetylglucosamine-6-Sulfatase, GNS, Glucosamine-6-Sulfatase, G6S
Anti-GNS Antibody (8V673) is a Mouse antibody targeting GNS. Anti-GNS Antibody (8V673) can be used in ELISA.
Anti-GNS Antibody (8V673)
Anti-GNS Antibody (8V673)
😃Good
Catalog No. TMAY-00605Alias N-Acetylglucosamine-6-Sulfatase, GNS, Glucosamine-6-Sulfatase, G6S
Anti-GNS Antibody (8V673) is a Mouse antibody targeting GNS. Anti-GNS Antibody (8V673) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $199 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: ELISA Reactivity: Human |
| Alias | N-Acetylglucosamine-6-Sulfatase, GNS, Glucosamine-6-Sulfatase, G6S |
| Ig Type | Mouse IgG2b |
| Clone | 8V673 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human GNS / G6S (rhGNS; NP_002067.1Met 1-Leu 552). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Glucosamine (N-acetyl)-6-sulfatase (GNS), also known as G6S, a hydrolase, which is one of the enzymes involved in heparan sulfate catabolism leading to lysosomal storage. GNS is required for the catabolism of the glycosaminoglycans (GAG) including heparin, heparan sulfate, and keratan sulfate through the hydrolysis of the 6-sulfate group from the N-acetyl-D-glucosamine 6-sulfate units. Mucopolysaccharidosis type IIID (MPS IIID) is the least common of the four subtypes of Sanfilippo syndrome. It is caused by a deficiency of N-acetylglucosamine-6-sulphatase. A mutation in GNS resulting in MPS IIID indicates the potential utility of molecular diagnosis for this rare condition. As the least common type of the four subtypes of Sanfilippo syndrome, MPS IIID has profound mental deterioration, hyperactivity, and relatively mild somatic manifestations. |
| Conjucates | Unconjugated |
| Immunogen | Human cell-derived rhGNS |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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