dt

DT-061, an orally bioavailable protein phosphatase 2A (PP2A) activator, may be used in the therapy of KRAS-mutant and MYC-driven tumorigenesis.

DT204 is an SCFSkp2 inhibitor that reduces the binding of Skp2 to Cullin-1 and Commd1. It can be used to study multiple myeloma.

(1S,2S,3R)-DT-061, an enantiomer of DT-061, is an orally bioavailable activator of PP2A.

DT2216 inhibits various Bcl-XL-dependent leukemias and cancer cells, but is significantly less toxic to platelets.DT2216 is a selective B-cell lymphoma, extremely large (BCL-XL), proteolytic targeting chimera (PROTAC).DT2216 targets bcl-XL to the Von Hipp

5'-O-TBDMS-dT is a nucleoside characterized by its protective and modification effects.

5'-O-DMT-dT (5'-O-(4,4'-Dimethoxytrityl)thymidine) is a nucleoside derivative used in oligonucleotide synthesis.

DMT-dT Phosphoramidite is commonly utilized in DNA synthesis.

DT-2 acetate, a selective cGMP-dependent protein kinase (PKG) inhibitor, is a mouse monoclonal antibody targeting canine thymocytes.DT-2 acetate inhibits PKG-catalyzed phosphorylation, reverses 8-Br-cGMP-induced expansion, and can be used to study immune disorders.

Vadimezan (DMXAA) is a vascular disrupting agent, a murine STING agonist, and an inducer of cytokines such as type I IFN. Vadimezan has antitumor activity and induces a rapid cessation of blood flow in tumors without affecting blood flow in normal tissues.

Selodenoson (RG-14202) is a selective adenosine A1 receptor agonist used to slow the heart rate in patients with atrial fibrillation and to treat arrhythmias.

SMAP-2 is an orally bioavailable activator of phosphatase 2A (PP2A) which binds to the PP2A Aα scaffold subunit to drive conformational changes in PP2A. It inhibits the growth of KRAS-mutant lung cancers .

Bucladesine is a cyclic nucleotide derivative which mimics the action of endogenous cAMP and is capable of permeating the cell membrane. Bucladesine is a phosphodiesterase inhibitor. The compound is used in a wide variety of research applications because

Samixogrel functions as both an inhibitor of the thromboxane A2 receptor (thromboxane A2 receptor) and a suppressor of thromboxane synthesis (thromboxane synthesis).

4F-Docetaxel (4FDT) is a fluorinated derivative of docetaxel that exhibits significant antitumor activity against hepatocellular carcinoma (HCC) and is suitable for research on liver cancer.

2'-F T Amidite (DMTr-2'-F-dT-3'-CE-phosphoramidite) is a monomer used in nucleic acid synthesis.

3'-O-Phthalimido-2'-deoxythymidine (3'-O-phthalimido-2'-dT) is a monomeric material utilized in the synthesis of nucleic acids.

Bilirubin ditaurine is a synthetic analog of conjugated bilirubin that can completely inhibit oxidation of phosphatidylcholine induced by peroxyl radicals in multilayer liposomes or micelles. While bilirubin ditaurine itself does not significantly decompose 18:2-OOH, it greatly accelerates copper ion-catalyzed decomposition of 18:2-OOH. Bilirubin ditaurine is useful for studying the detoxification effects of conjugated bilirubin.

Dth is a proteolysis-targeting chimera (PROTAC) composed of the fluorescent RNA probe DFHBI and the immunomodulatory compound thalidomide.

DT-23 is a potent antifungal agent with a MIC50 of 15 μg/mL. It inhibits recombinant Arg1 and Kcs1, with IC50 values of 0.6 μM and 0.68 μM, respectively.

TPA-dT is a thymidine analogue featuring a tris[(2-pyridyl)methyl]amine moiety. It is utilized for the modification of siRNA. The siRNA modified with TPA remains functionally inactive and cannot silence gene expression until the TPA component is removed upon exposure to Cu(I), subsequently activating its functionality.

DT-6, a potent TGF-β1 inhibitor, impedes M2 macrophage-induced epithelial-to-mesenchymal transition and the invasive migration of cancer cells, thereby showing potential for cancer research applications [1].

DT-2 serves as a potent, selective inhibitor of cGMP-dependent protein kinase (PKG), with a Ki of 12.5 nM, effectively hindering PKG-catalyzed phosphorylation [1].

3'-O-Azidomethylene-dT is a monomeric material employed in the synthesis of nucleic acids.

DT-3, a membrane-permeable inhibitory peptide, targets protein kinase G Iα and guanylyl cyclase ?. It effectively blocks the cGMP–PKG signalling pathway [1].