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Search Results for " oxidative "

Targets

293

Compounds

204

Natural Products

138

Recombinant Proteins

7

Libraries

Cat No. Product Name Synonyms Targets
T5116 Iprodione Others , Reactive Oxygen Species , Antifungal
Iprodione is a fungicide. Iprodione is also used in cannabis testing kits as a component of pesticide mixes.
T25049 Allethrin BCL , Caspase
Allethrin induces oxidative stress, apoptosis and calcium release. Allethrin, a pyrethroid insecticide is a major mosquito repellent agent.
T7845 BTZO-1 Apoptosis
BTZO-1 is an antioxidant response element (ARE) activator with cardioprotective activity.
T0734 Antipyrine Phenazone,Phenazon COX
Antipyrine (Phenazone), an antipyretic and analgesic, has been given as ear drops and by mouth. Antipyrine is frequently used to test the effects of other diseases or drugs on drug-metabolizing enzymes in the liver.
T7042 1,5-Isoquinolinediol PARP
1, 5-Isoquinolinediol is an inhibitor of poly(ADP-ribose) synthetase (PARP1; IC50: 0.39 μM). The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis. 1, 5-Isoquinolinediol...
T8391 Cesium chloride CsCl Potassium Channel
Cesium chloride (CsCl) is considered to be the most toxic of the alkali chlorides, inhibiting fungal growth.
T60034 TH1085 Others
TH1085 is an enhancer of OGG1. TH1085 stimulates DNA repair and protects cells from the environmental hazard paraquat (PQ).
T8500 VLX600 OXPHOS , Mitochondrial Metabolism , Autophagy
VLX600 is an iron-chelating oxidative phosphorylation (OXPHOS) inhibitor, is a cell-permeable anticancer agent. It acts by reducing mitochondrial oxidative phosphorylation in tumor cells.
T21902 ML351 Lipoxygenase
ML351 is a potent and selective inhibitor of human 15-lipoxygenase-1 (15 LOX)(IC50: 200 nM).
T7093 Rafoxanide CDK , Parasite
Rafoxanide as a dual CDK4/6 inhibitor for the treatment of skin cancer. Rafoxanide is a salicylanilide used as an anthelmintic. It is used to treat fluke, hookworm and other infestations.
T5345 V-9302 Others
V-9302 (V9302) is a competitive antagonist of transmembrane glutamine flux that selectively and potently targets the amino acid transporter ASCT2 (IC50: 9.6 uM).
T5486 RU.521 RU320521 DNA , cGAS
RU.521 (RU3205217) is a potent dsDNA inhibitor (IC50 : 700 nM), inhibition of the dsDNA pathway by RU.521 requires the presence of cGAS.
T14042 4-P-PDOT 4-phenyl-2- propionamidotetralin Melatonin Receptor , MT Receptor
4-P-PDOT (4-phenyl-2- propionamidotetralin) is a potent, selective and affinity Melatonin receptor (MT2) antagonist.
T5827 BI-6C9 Apoptosis , Others , Mitochondrial Metabolism
BI-6C9 is an inhibitor of tBid (Kd = 20 µM).BI-6c9 prevented MOMP and mitochondrial fission, and protected the cells from cell death.
T6708 Tolcapone Tasmar,Ro 40-7592 Apoptosis , Beta Amyloid , Transferase
Tolcapone (Ro 40-7592) is a catechol-O-methyltransferase inhibitor used in the therapy of Parkinson disease as adjunctive therapy in combination with levodopa and carbidopa.
T9211 Mito-LND Mito-Loidamine OXPHOS , Reactive Oxygen Species , Mitochondrial Metabolism , Autophagy
Mito-LND (Mito-Loidamine) is an orally active and mitochondria-targeted inhibitor of oxidative phosphorylation.
T0412 Idebenone CV-2619 Apoptosis , Antioxidant , Mitochondrial Metabolism
Idebenone (CV-2619) is a synthetic analogue of ubiquinone (Coenzyme Q10), a vital cell antioxidant and essential component of the Electron Transport Chain (ETC).
T23550 YM-750 YM 750 Acyltransferase
YM-750 is a potent inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT), with an IC50 value of 0.18 μM. ACAT is an enzyme that catalyzes the conversion of cholesterol and long-chain fatty-acyl-coenzyme A into cholest...
TP1929L1 Saralasin acetate(34273-10-4 free base) RAAS
Saralasin acetate is a Non-selective angiotensin II antagonist.
T5337 IACS-010759 IACS-10759,IACS 10759,IACS10759 Apoptosis , Others , Mitochondrial Metabolism
IACS-010759 is an orally bioavailable inhibitor of complex I of oxidative phosphorylation of the mitochondrial electron transport chain.
T40192 DGTP 2'-Deoxyguanosine-5'-triphosphate Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis
dGTP (2'-Deoxyguanosine-5'-triphosphate) is one of the guanosine nucleotides which is highly susceptible to oxidative damage to 8-O-GDP, 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.
T5371 L-BUTHIONINE-(S,R)-SULFOXIMINE L-Butionine sulfoximine Others , Ferroptosis
L-Buthionine-(S,R)-sulfoximine is a cell-permeable and irreversible inhibitor of γ-glutamylcysteine synthetase (Ki <100 μM) that induces oxidative stress in cells by depleting GSH.
T39308 Boc-Asp(OMe)-fluoromethyl ketone Boc-Asp(OMe)-fluoromethyl ketone,Boc-Asp(OMe)-FMK Caspase
Boc-Asp(OMe)-fluoromethyl ketone (Boc-Asp(OMe)-FMK) is a broad range caspase inhibitor. Boc-Asp(OME)-Fluoromethyl Ketone inhibits Fas-mediated phagocytosis and oxidative rupture inhibition, but does not affect the chemot...
T13920L Terlipressin Acetate Terlipressin diacetate anhydrous,Terlipressin acetate anhydrous Vasopressin Receptor
Terlipressin Acetate, a highly selective vasopressin V1 receptor agonist, on oxygen and glucose deprivation/re-oxygenation (OGD/R)-induced damage in intestinal epithelial cells (IEC-6).Terlipressin acetate exerts anti-in...
T23146 PHA 568487 free base PHA 568487 AChR
The quinuclidine PHA 568487 free base is an agonist of the alpha 7 nicotinic acetylcholine receptor that was designed to mitigate the bioactivation associated with the core scaffold and subsequently remove associated lia...
T6170 Elesclomol STA-4783 Apoptosis , HSP , Reactive Oxygen Species
Elesclomol (STA-4783) is an oxidative stress inducer and a highly lipophilic copper ion carrier. Elesclomol induces apoptosis in tumor cells and is used in copper death related studies. Elesclomol also inhibits FDX1-medi...
T9516 Binodenoson WRC 0470,MRE-0470,2-(cyclohexylmethylidenehydrazino)adenos Adenosine Receptor
Binodenoson (WRC 0470) is a potent and selective A2A adenosine receptor agonist (KD=270 nM). Binodenoson is being developed as a short-acting coronary vasodilator as an adjunct to radiotracers for use in myocardial stres...
T22309 2,5-Dimethyl-3(2H)-furanone 2,5-Dimethyl-2,3-dihydrofuran-3-one Others
2,5-Dimethyl-3(2H)-furanone (2,5-Dimethyl-2,3-dihydrofuran-3-one) is a non-genotoxic flavoring substance [1].
T1487 Fluvastatin sodium XU 62320 sodium,XU-62-320,Fluvastatin sodium salt Ferroptosis , HMG-CoA Reductase , Autophagy
Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterol lowering agent.
T20684 2',7'-Dichlorofluorescein diacetate Diacetyldichlorofluorescein,Leuco-dcf diacetate,Dcfh-DA,DCFDA Others
2',7'-Dichlorofluorescein diacetate (Diacetyldichlorofluorescein), a cell-permeable fluorogenic probe, is useful for the detection of nitric oxide (NO) and reactive oxygen species (ROS) and for the determination of the d...
T8842 IMT1B 3-Piperidinecarboxylic acid, 1-[(2R)-2-[[4-(2-chloro-4-fluorophenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-1-oxopropyl]-, (3S)-,LDC203974 Others , DNA/RNA Synthesis
IMT1B (LDC203974) is an orally administered, specific noncompetitive allosteric inhibitor of the mitochondrial RNA polymerase (POLRMT), effectively suppressing mitochondrial DNA (mtDNA) expression. This action confers it...
T10512 Prenyl-IN-1 Transferase
Prenyl-IN-1 is a potent and selective prenylation inhibitor of geranylgeranyltransferase or farnesyltransferase.Prenyl-IN-1 shows anti-oxidative stress effects in a Parkinson's model. Prenyl-IN-1 showed anti-oxidative st...
T2225 4-Hydroxyantipyrine COX
4-Hydroxyantipyrine is formed during oxidative deamination of aminopyrine.
T20543 Flurochloridone R 40244,R-40244,R40244,EPA Pesticide Chemical Code 128401 Apoptosis , Reactive Oxygen Species
Flurochloridone (R 40244) is a selective herbicide. Flurochloridone induces apoptosis and is regulated by mitochondrial dysfunction and oxidative stresses.
T25441 Fructosylvaline Fru-val,N-Fructosyl Valine Others
Fructosylvaline(Fru-val) is present in miso, white wine and sake and has been associated with oxidative browning of white wine and sake.
T21899 Misonidazole SR-1354,SR1354,Ro 7-0582 GPX
Misonidazole as a novel GPX inhibitors to cause oxidative stress in chemotherapy-resistant tumors.
T18976 Dihydrofluorescein diacetate Diacetyldihydrofluorescein Others
Dihydrofluorescein diacetate (Diacetyldihydrofluorescein) is a fluorescent probe for measuring oxidative stress in cell-free systems and cellular models.
T13436 (E)-[6]-Dehydroparadol (6)-Dehydroparadol Nrf2
(E)-[6]-Dehydroparadol ((6)-Dehydroparadol), an oxidative metabolite of [6]-Shogaol, is a potent Nrf2 activator.
T5913 Sulbutiamine Bisibuthiamine Antioxidant
Sulbutiamine (Bisibuthiamine) is an antioxidant that act by inhibiting oxidative stress induced retinal ganglion cell death.
T20318 Benzylideneaniline N-Benzylideneaniline Others
Benzylideneaniline (N-Benzylideneaniline) is a potent inhibitor of xyloglucan-α,β-dioxygenase, a key enzyme in the oxidative cleavage of the central double bond of xyloglucan.
T12059L Mitoquinone mesylate MitoQ mesylate,MitoQ10 mesylate Reactive Oxygen Species
Mitoquinone mesylate (MitoQ10 mesylate) is a TPP-based, mitochondrially targeted antioxidant to protect against oxidative damage.
T22963 McN-A 343 AChR
McN-A 343 is a selective M1 muscarinic agonist known for its ability to stimulate muscarinic transmission in sympathetic ganglia. It has been found to effectively reduce inflammation and oxidative stress in experimental ...
T15373 Gboxin ATPase , Mitochondrial Metabolism
Gboxin is an inhibitor of oxidative phosphorylation that targets glioblastoma,inhibits the activity of F0F1 ATP synthase, with antitumour activity.
T1710 Trolox Apoptosis , Antioxidant , Ferroptosis , Reactive Oxygen Species
Trolox is a vitamin E analogue, used in reducing oxidative stress or damage.
T12019 Methylproamine Others
Methylproamine is a DNA-binding radioprotector , acts by repair of transient radiation-induced oxidative species on DNA.
T6834 FCCP Carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone,Trifluoromethoxy carbonylcyanide phenylhydrazone ATPase , Mitochondrial Metabolism
FCCP (Trifluoromethoxy carbonylcyanide phenylhydrazone) is an oxidative phosphorylation (OXPHOS) inhibitor and mitochondrial proton carrier uncoupler. FCCP is often used as an apoptosis inducer.
T34076 Piprozolin W3699,W-3699,W 3699
Piprozolin (W 3699) is a new type of choleretic acid that shows slight analgesic properties at high doses during chronic experiments.Piprozolin has a slight induction of certain enzymes of the oxidative system.
T5837 Tamerit Others
Tamerit as an efficient inhibitor of oxidative burst in monocytes.
T72082 Compound T72082(SC) ROS
ROS-IN-1 is a mitochondrial ROS inhibitor that can be used to reduce oxidative stress or inhibit reactive oxygen species (ROS) production.
T24905 TT01001 TT-01001,TT 01001,Ethyl 4-(3-(3,5-dichlorophenyl)thioureido)piperidine-1-carboxylate Mitochondrial Metabolism
TT01001 (Ethyl 4-(3-(3,5-dichlorophenyl)thioureido)piperidine-1-carboxylate) is a selective agonist of mitoNEET and reduces oxidative stress injury and neuronal apoptosis by improving mitochondrial dysfunction. TT01001 c...

Compounds

Iprodione
T5116
Synonym:
Target: Others, Reactive Oxygen Species, Antifungal
Allethrin
T25049
Synonym:
Target: BCL, Caspase
BTZO-1
T7845
Synonym:
Target: Apoptosis
Antipyrine
T0734
Synonym: Phenazone,Phenazon
Target: COX
1,5-Isoquinolinediol
T7042
Synonym:
Target: PARP
Cesium chloride
T8391
Synonym: CsCl
Target: Potassium Channel
TH1085
T60034
Synonym:
Target: Others
VLX600
T8500
Synonym:
Target: OXPHOS, Mitochondrial Metabolism, Autophagy
ML351
T21902
Synonym:
Target: Lipoxygenase
Rafoxanide
T7093
Synonym:
Target: CDK, Parasite
V-9302
T5345
Synonym:
Target: Others
RU.521
T5486
Synonym: RU320521
Target: DNA, cGAS
4-P-PDOT
T14042
Synonym: 4-phenyl-2- propionamidotetralin
Target: Melatonin Receptor, MT Receptor
BI-6C9
T5827
Synonym:
Target: Apoptosis, Others, Mitochondrial Metabolism
Tolcapone
T6708
Synonym: Tasmar,Ro 40-7592
Target: Apoptosis, Beta Amyloid, Transferase
Mito-LND
T9211
Synonym: Mito-Loidamine
Target: OXPHOS, Reactive Oxygen Species, Mitochondrial Metabolism, Autophagy
Idebenone
T0412
Synonym: CV-2619
Target: Apoptosis, Antioxidant, Mitochondrial Metabolism
YM-750
T23550
Synonym: YM 750
Target: Acyltransferase
Saralasin acetate(34273-10-4 free base)
TP1929L1
Synonym:
Target: RAAS
IACS-010759
T5337
Synonym: IACS-10759,IACS 10759,IACS10759
Target: Apoptosis, Others, Mitochondrial Metabolism
dGTP
T40192
Synonym: 2'-Deoxyguanosine-5'-triphosphate
Target: Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis
L-BUTHIONINE-(S,R)-SULFOXIMINE
T5371
Synonym: L-Butionine sulfoximine
Target: Others, Ferroptosis
Boc-Asp(OMe)-fluoromethyl ketone
T39308
Synonym: Boc-Asp(OMe)-fluoromethyl ketone,Boc-Asp(OMe)-FMK
Target: Caspase
Terlipressin Acetate
T13920L
Synonym: Terlipressin diacetate anhydrous,Terlipressin acetate anhydrous
Target: Vasopressin Receptor
PHA 568487 free base
T23146
Synonym: PHA 568487
Target: AChR
Elesclomol
T6170
Synonym: STA-4783
Target: Apoptosis, HSP, Reactive Oxygen Species
Binodenoson
T9516
Synonym: WRC 0470,MRE-0470,2-(cyclohexylmethylidenehydrazino)adenos
Target: Adenosine Receptor
2,5-Dimethyl-3(2H)-furanone
T22309
Synonym: 2,5-Dimethyl-2,3-dihydrofuran-3-one
Target: Others
Fluvastatin sodium
T1487
Synonym: XU 62320 sodium,XU-62-320,Fluvastatin sodium salt
Target: Ferroptosis, HMG-CoA Reductase, Autophagy
2',7'-Dichlorofluorescein diacetate
T20684
Synonym: Diacetyldichlorofluorescein,Leuco-dcf diacetate,Dcfh-DA,DCFDA
Target: Others
IMT1B
T8842
Synonym: 3-Piperidinecarboxylic acid, 1-[(2R)-2-[[4-(2-chloro-4-fluorophenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-1-oxopropyl]-, (3S)-,LDC203974
Target: Others, DNA/RNA Synthesis
Prenyl-IN-1
T10512
Synonym:
Target: Transferase
4-Hydroxyantipyrine
T2225
Synonym:
Target: COX
Flurochloridone
T20543
Synonym: R 40244,R-40244,R40244,EPA Pesticide Chemical Code 128401
Target: Apoptosis, Reactive Oxygen Species
Fructosylvaline
T25441
Synonym: Fru-val,N-Fructosyl Valine
Target: Others
Misonidazole
T21899
Synonym: SR-1354,SR1354,Ro 7-0582
Target: GPX
Dihydrofluorescein diacetate
T18976
Synonym: Diacetyldihydrofluorescein
Target: Others
(E)-[6]-Dehydroparadol
T13436
Synonym: (6)-Dehydroparadol
Target: Nrf2
Sulbutiamine
T5913
Synonym: Bisibuthiamine
Target: Antioxidant
Benzylideneaniline
T20318
Synonym: N-Benzylideneaniline
Target: Others
Mitoquinone mesylate
T12059L
Synonym: MitoQ mesylate,MitoQ10 mesylate
Target: Reactive Oxygen Species
McN-A 343
T22963
Synonym:
Target: AChR
Gboxin
T15373
Synonym:
Target: ATPase, Mitochondrial Metabolism
Trolox
T1710
Synonym:
Target: Apoptosis, Antioxidant, Ferroptosis, Reactive Oxygen Species
Methylproamine
T12019
Synonym:
Target: Others
FCCP
T6834
Synonym: Carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone,Trifluoromethoxy carbonylcyanide phenylhydrazone
Target: ATPase, Mitochondrial Metabolism
Piprozolin
T34076
Synonym: W3699,W-3699,W 3699
Target:
Tamerit
T5837
Synonym:
Target: Others
Compound T72082(SC)
T72082
Synonym:
Target: ROS
TT01001
T24905
Synonym: TT-01001,TT 01001,Ethyl 4-(3-(3,5-dichlorophenyl)thioureido)piperidine-1-carboxylate
Target: Mitochondrial Metabolism
1 2 3 4 5 6
Cat No. Product Name Synonyms Targets
T2738 Dehydroandrographolide NOS , Influenza Virus
Dehydroandrographolide is a natural compound extracted from herbal medicine Andrographis paniculata (Burm f) Nees.
TC0039 Vasicinone Others
Vasicinone may act as a hepatoprotective agent. (±)-Vasicinone has significant antitussive, expectorant, and bronchodilating activities, which can be used to treat respiratory disease.(S)-Vasicinone exhibits antiprolifer...
T2S1720 Huperzine B AChE
1. Huperzine-B is a efficient inhibitor of human brain AChE. 2. Huperzine-B can enhance ognitive and protect neuro, may be potentially new drug candidates for Alzheimer's disease therapy.
T7982 3,6-Dihydroxyflavone Others
3,6-Dihydroxyflavone suppresses the epithelial-mesenchymal transition in breast cancer cells by inhibiting the Notch signaling pathway.
T5783 Rosamultin Antioxidant , HIV Protease
Rosamultin has antioxidant, antiinflammatory/antinociceptive properties,and has anti-human immunodeficiency virus (HIV) activity.
T13795 Nicotinamide riboside Sirtuin
Nicotinamide riboside increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-induced metabolic abnormalities.
T8678 Naphthazarin 5,8-Dihydroxy-1,4-naphthoquinone,DHNQ Apoptosis
Naphthazarin (5,8-Dihydroxy-1,4-naphthoquinone) is effective by various cellular mechanisms including oxidative stress, activation of mitochondrial apoptosis-inducing factor (AIF), depolymerization of microtubules, inter...
T41358 2-Hydroxybenzylamine Others
2-Hydroxybenzylamine, a potent small molecule scavenger of IsoLGs, sequesters the reactive species as inert adducts. 2-Hydroxybenzylamine may be used to decrease early recurrence of atrial fibrillation and other atrial a...
TN2100 Pratensein Others , NF-κB
Pratensein as a novel transcriptional up-regulator of scavenger receptor class B type I in HepG2 cells.
T3394 Timosaponin BII Prototimosaponin A III Beta Amyloid , Others , BACE
Timosaponin BII (Prototimosaponin A III) has anti-dementia activity and may be useful for the treatment of type 2 diabetes. Timosaponin BII has antioxidant activity, can inhibit the up-regulation of BACE1 and reduced the...
T3S1265 Liriopesides B Nolinospiroside F Others
Liriopesides B (Nolinospiroside F) exhibited potential anticancer activity against human ovarian cancer A2780 cells.
TN1039 Tamarixetin 4'-O-Methyl Quercetin Endogenous Metabolite , Immunology/Inflammation related
Tamarixetin (4'-O-Methyl Quercetin) (4'-O-Methyl Quercetin) is a natural flavonoid derivative of quercetin, with anti-inflammatory and anti-oxidative effects. Tamarixetin protects against cardiac hypertrophy.
TN2244 Sulfuretin NF-κB , Autophagy
Sulfuretin is a potent anti-oxidant, has protective effect against t-BHP-induced oxidative damage in human liver-derived HepG2 cells is attributable to its ability to scavenge ROS and up-regulate the activity of HO-1 thr...
T5669 Citric acid monohydrate Others
Citric Acid Monohydrate is a tricarboxylic acid found in citrus fruits. Citric acid is used as an excipient in pharmaceutical preparations due to its antioxidant properties. It maintains stability of active ingredients a...
T5S0636 Citric acid Citro,Citretten Apoptosis , Others , Endogenous Metabolite , Antibacterial , Antibiotic
1. Citric acid (Citro) (1-2 g/kg) can decrease brain lipid peroxidation and inflammation, liver damage, and DNA fragmentation. 2. Citric acid denture cleansers can reduce C. albicans biofilm accumulation and cell viabili...
TN1926 Methyl caffeate Methyl caffeate acid Others , Antibacterial
Methyl caffeate (Methyl caffeate acid) acid
T2800 L-Theanine Apoptosis , Others
L-Theanine is a relaxing and nondietary amino acid found pretty much exclusively in teas from Camellia sinensis and is known to promote relaxation without sedation.
T10148 4-Hydroxynonenal 4-HNE Dehydrogenase , Endogenous Metabolite
4-Hydroxynonenal (4-HNE) (4-HNE) is an oxidative/nitrosative stress biomarker. It is a substrate and an inhibitor of acetaldehyde dehydrogenase 2 (ALDH2).
T3S1319 (+)-Magnoflorine Escholin,Magnoflorine,Thalictrin,Escholine Others , Antifungal
(+)-Magnoflorine (Thalictrin) has sedative and anxiolytic effects, probably mediated by Magnoflorine through a GABAergic mechanism of action. Magnoflorine and Sinomenine have protective effects, are mediated by some mech...
TJO2742 DL-Methionine methionine,Acimetion,Racemethionine Parasite
DL-Methionine (Acimetion) is an amino acid. Amino acids are the building blocks that our bodies use to make proteins. DL-Methionine is found in meat, fish, and dairy products. It plays an important role in the many funct...
T2230 Paeoniflorin Peoniflorin HSP , COX
Paeoniflorin (Peoniflorin) is a herbal constituent extracted from the root of Paeonia albiflora Pall.
T6220 Nicotinamide riboside chloride Sirtuin , Endogenous Metabolite
Nicotinamide riboside chloride, also known as NR and SRT647, is a pyridine-nucleoside form of vitamin B3 that functions as a precursor to nicotinamide adenine dinucleotide or NAD+.
T0626 Uric Acid 2,6,8-Trioxopurine,2,6,8-Trioxypurine,2,6,8-Trihydroxypurine,Lithic acid,Urate Reactive Oxygen Species , Endogenous Metabolite , Phosphorylase
Uric Acid (Lithic acid) is an oxidation product of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE ...
T20793 Magnesium Lithospermate B Monomethyl lithospermate B,Lithospermate B Others
Magnesium Lithospermate B is a natural product activates eNOS and ameliorates endothelial dysfunction in diabetes by enhancing vasodilation in addition to reducing oxidative stress, it can protecte cardiomyocytes from is...
T2198 Arecoline hydrobromide Arecoline HBr,Arecoline bromide AChR
Arecoline hydrobromide (Arecoline HBr) is a muscarinic acetylcholine receptor agonist.
T7917 4'-Hydroxychalcone 2-Benzal-4-Hydroxyacetophenone Proteasome
4'-Hydroxychalcone (2-Benzal-4-Hydroxyacetophenone) is a chalcone metabolite with hepatoprotective activity
TN6339 (R)-5-Hydroxy-1,7-diphenylheptan-3-one (5R)-Dihydroyashabushiketol Others
(R)-5-Hydroxy-1,7-diphenylheptan-3-one ((5R)-Dihydroyashabushiketol) is extracted from the rhizomes of Alpinia officinarum, a Chinese medicinal herb. (R)-5-Hydroxy-1,7-diphenylheptan-3-one inhibits melanogenesis in theop...
T3S1068 Oxyresveratrol trans-Oxyresveratrol,2,3',4,5'-tetrahydroxystilbene,Tetrahydroxystilbene Tyrosinase , Autophagy , HSV
1. Oxyresveratro can inhibit tyrosinase activity. 2. Oxyresveratro is useful to trauma models, as toxicity to glia could be beneficial by inhibiting reactive gliosis. 3. Oxyresveratrol (trans-Oxyresveratrol) has antioxid...
T3982 Vulpinic Acid Vulpic acid,Pulvinic acid methyl ester Others
Vulpinic Acid (Pulvinic acid methyl ester) is a lichen metabolite with anti-inflammatory, antibacteria, properties, plant growth inhibitor.
T3S1320 (+)-Magnoflorine iodide Magnoflorine iodide,Thalictrine iodide,Corytuberine Methiodide Others , Antifungal
(+)-Magnoflorine iodide (Thalictrine iodide) has anti-inflammatory activity, it can inhibit inflammations.
T6S0117 Avicularin Fenicularin ERK
Avicularin (Fenicularin) has anti-allergic, anti-inflammatory, hepatoprotective, antioxidant, anti-tumor and other activities. It ameliorates human hepatocellular carcinoma by modulating the activities of NF-κB(p65), COX...
T4S1321 (+)-Magnoflorine chloride Magnoflorine chloride,Corytuberine methochloride,Thalictrine chloride,Escholine chloride Others , Antifungal
(+)-Magnoflorine chloride (Escholine chloride) has anti-inflammatory activity, it can inhibit inflammations.
T8193 α-Thujone Thujone,ALPHA-(-)-THUJONE Apoptosis , Reactive Oxygen Species , GABA Receptor , AChR , Parasite , Autophagy
α-Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.
T2870 Matrine Vegard,Matridin-15-one,Matrinium,α-Matrine,(+)-Matrine Mitophagy , Ferroptosis , Opioid Receptor , Autophagy
Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.
T9454 4-Hydroxyestrone Estrogen Receptor/ERR , Endogenous Metabolite
4-Hydroxyestrone, an endogenous estrogen metabolite, can strongly protect neuronal cells against oxidative damage.
T37710 5-Hydroxyoxindole Reactive Oxygen Species
5-Hydroxyoxindole has been identified as a urinary metabolite of indole, which is produced from tryptophane via the tryptophanase activity of gut bacteria [1]. 5-Hydroxyoxindole has lipid peroxidation inhibition activit...
TN6909 Polyporusterone B (1R,2R,4S,5R,7R,11R,14S,15R)-14-[(2R,3R)-2,3-dihydroxy-6-methyl-5-methylideneheptan-2-yl]-4,5,11-trihydroxy-2,15-dimethyltetracyclo[8.7.0.02,?.011,1?]heptadec-9-en-8-one Others
Polyporusterone B ((1R,2R,4S,5R,7R,11R,14S,15R)-14-[(2R,3R)-2,3-dihydroxy-6-methyl-5-methylideneheptan-2-yl]-4,5,11-trihydroxy-2,15-dimethyltetracyclo[8.7.0.02,?.011,1?]heptadec-9-en-8-one) is a triterpene carboxylic aci...
T20597 Alginic acid Protanal LF,Snow acid algin G,Kelacid,Sazzio,Norgine Apoptosis , Autophagy , Histamine Receptor
Alginic acid (Snow acid algin G) is a natural polysaccharide extracted from brown seaweeds with anti-anaphylactic and anti-inflammatory activities. Alginic acid inhibits histamine release and can be used in the food indu...
TN6924 Anhydrosafflor yellow B (2S,3S)-6,7-dihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-2-[(1S,2R,3R)-1,2,3,4-tetrahydroxybutyl]-3-{2,3,4-trihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-6-oxo-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]cyclohexa-1,4-dien-1,AHSYB Others
Anhydrosafflor yellow B ((2S,3S)-6,7-dihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-2-[(1S,2R,3R)-1,2,3,4-tetrahydroxybutyl]-3-{2,3,4-trihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-6-oxo-3-[(2R,3R,4S,5S,6R)-3,4,...
TN1461 (-)-Butin Butin Akt , PI3K , Nrf2
(-)-Butin (Butin) has antioxidant activity, can protect cells against H2O2-induced apoptosis, oxidative DNA damage and oxidative mitochondrial dysfunction; it attenuates oxidative stress by activating Nrf2-mediated Mn SO...
T2S2003 Phlorizin dihydrate Phloridzin dihydrate Others
1. Phlorizin dihydrate (Phloridzin dihydrate) can significantly inhibit oxidative DNA damage.
T8177 Galactinol Others
Galactinol Hydrate scavenges hydroxyl free radicals and protects plant cells from oxidative damage.
T6S1966 Curculigoside Curculigoside A Antioxidant , NF-κB , JAK , STAT
1. Curculigoside (Curculigoside A) can prevent bone loss , improve osteogenesis and inhibit osteoclastogenesis of hAFSCs, suggesting its potential use to regulate hAFSC osteogenic differentiation for treating bone disord...
T2S2172 Nerolidol (±)-Nerolidol,Peruviol Others , Endogenous Metabolite , Antibacterial , Parasite , Antifungal
Nerolidol (Peruviol) shows sedative effects in animals, oxidative process plays a crucial role on neuronal pathological consequence. Nerolidol is mainly related to ROS and DNA single strand breaks generated by the presen...
TN1600 Eclalbasaponin I Others
Eclalbasaponin I has anti-oxidative, and antitumor activities, it reduces oxidative stress-induced neural cell death by autophagy activation, it can dose-dependently inhibit the proliferation of hepatoma cell smmc-7721 w...
T19165 8-Hydroxyguanine 8 Hydroxyguanine,7,8-dihydro-8-oxoguanine,2-Amino-6,8-dihydroxypurine Endogenous Metabolite
8-Hydroxyguanine (8 Hydroxyguanine) is the major premutagenic damage produced by reactive oxygen species. It causes G-T and A-C substitutions.8-Hydroxyguanine is a biomarker for RNA oxidation and oxidative DNA damage.8-H...
T8704 4-hydroxyphenyl acetate Nrf2
4-Acetoxyphenol Prevents RPE Oxidative Stress-Induced Necrosis by Functioning as an NRF2 Stabilizer
T6S1768 Narcissin Isorhamnetin 3-Rutinoside,Narcissoside Antioxidant
Narcissin (Isorhamnetin 3-Rutinoside), with synergism of B.flavum flavonoid and rutin, could be responsible for stronger protection against mitochondrial induced oxidative stress.
T2805 Chlorogenic Acid NSC-407296,3-O-Caffeoylquinic acid,Heriguard Others , Influenza Virus , Reactive Oxygen Species , HIF/HIF Prolyl-Hydroxylase , Endogenous Metabolite , Antibacterial
Chlorogenic Acid (NSC-407296) is a naturally occurring phenolic acid which is a carcinogenic inhibitor. It has also been shown to prevent paraquat-induced oxidative stress in rats.
T2S1008 Oxysophoridine Sophoridine N-oxide Apoptosis , Antioxidant
Oxysophoridine (Sophoridine N-oxide) has a protective effect on focal cerebral ischemic injury through antioxidant and anti-apoptotic mechanisms; it may be a potential neuroprotective agent for cerebral ischemia injury, ...
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Natural Products

Dehydroandrographolide
T2738
Synonym:
Target: NOS, Influenza Virus
Vasicinone
TC0039
Synonym:
Target: Others
Huperzine B
T2S1720
Synonym:
Target: AChE
3,6-Dihydroxyflavone
T7982
Synonym:
Target: Others
Rosamultin
T5783
Synonym:
Target: Antioxidant, HIV Protease
Nicotinamide riboside
T13795
Synonym:
Target: Sirtuin
Naphthazarin
T8678
Synonym: 5,8-Dihydroxy-1,4-naphthoquinone,DHNQ
Target: Apoptosis
2-Hydroxybenzylamine
T41358
Synonym:
Target: Others
Pratensein
TN2100
Synonym:
Target: Others, NF-κB
Timosaponin BII
T3394
Synonym: Prototimosaponin A III
Target: Beta Amyloid, Others, BACE
Liriopesides B
T3S1265
Synonym: Nolinospiroside F
Target: Others
Tamarixetin
TN1039
Synonym: 4'-O-Methyl Quercetin
Target: Endogenous Metabolite, Immunology/Inflammation related
Sulfuretin
TN2244
Synonym:
Target: NF-κB, Autophagy
Citric acid monohydrate
T5669
Synonym:
Target: Others
Citric acid
T5S0636
Synonym: Citro,Citretten
Target: Apoptosis, Others, Endogenous Metabolite, Antibacterial, Antibiotic
Methyl caffeate
TN1926
Synonym: Methyl caffeate acid
Target: Others, Antibacterial
L-Theanine
T2800
Synonym:
Target: Apoptosis, Others
4-Hydroxynonenal
T10148
Synonym: 4-HNE
Target: Dehydrogenase, Endogenous Metabolite
(+)-Magnoflorine
T3S1319
Synonym: Escholin,Magnoflorine,Thalictrin,Escholine
Target: Others, Antifungal
DL-Methionine
TJO2742
Synonym: methionine,Acimetion,Racemethionine
Target: Parasite
Paeoniflorin
T2230
Synonym: Peoniflorin
Target: HSP, COX
Nicotinamide riboside chloride
T6220
Synonym:
Target: Sirtuin, Endogenous Metabolite
Uric Acid
T0626
Synonym: 2,6,8-Trioxopurine,2,6,8-Trioxypurine,2,6,8-Trihydroxypurine,Lithic acid,Urate
Target: Reactive Oxygen Species, Endogenous Metabolite, Phosphorylase
Magnesium Lithospermate B
T20793
Synonym: Monomethyl lithospermate B,Lithospermate B
Target: Others
Arecoline hydrobromide
T2198
Synonym: Arecoline HBr,Arecoline bromide
Target: AChR
4'-Hydroxychalcone
T7917
Synonym: 2-Benzal-4-Hydroxyacetophenone
Target: Proteasome
(R)-5-Hydroxy-1,7-diphenylheptan-3-one
TN6339
Synonym: (5R)-Dihydroyashabushiketol
Target: Others
Oxyresveratrol
T3S1068
Synonym: trans-Oxyresveratrol,2,3',4,5'-tetrahydroxystilbene,Tetrahydroxystilbene
Target: Tyrosinase, Autophagy, HSV
Vulpinic Acid
T3982
Synonym: Vulpic acid,Pulvinic acid methyl ester
Target: Others
(+)-Magnoflorine iodide
T3S1320
Synonym: Magnoflorine iodide,Thalictrine iodide,Corytuberine Methiodide
Target: Others, Antifungal
Avicularin
T6S0117
Synonym: Fenicularin
Target: ERK
(+)-Magnoflorine chloride
T4S1321
Synonym: Magnoflorine chloride,Corytuberine methochloride,Thalictrine chloride,Escholine chloride
Target: Others, Antifungal
α-Thujone
T8193
Synonym: Thujone,ALPHA-(-)-THUJONE
Target: Apoptosis, Reactive Oxygen Species, GABA Receptor, AChR, Parasite, Autophagy
Matrine
T2870
Synonym: Vegard,Matridin-15-one,Matrinium,α-Matrine,(+)-Matrine
Target: Mitophagy, Ferroptosis, Opioid Receptor, Autophagy
4-Hydroxyestrone
T9454
Synonym:
Target: Estrogen Receptor/ERR, Endogenous Metabolite
5-Hydroxyoxindole
T37710
Synonym:
Target: Reactive Oxygen Species
Polyporusterone B
TN6909
Synonym: (1R,2R,4S,5R,7R,11R,14S,15R)-14-[(2R,3R)-2,3-dihydroxy-6-methyl-5-methylideneheptan-2-yl]-4,5,11-trihydroxy-2,15-dimethyltetracyclo[8.7.0.02,?.011,1?]heptadec-9-en-8-one
Target: Others
Alginic acid
T20597
Synonym: Protanal LF,Snow acid algin G,Kelacid,Sazzio,Norgine
Target: Apoptosis, Autophagy, Histamine Receptor
Anhydrosafflor yellow B
TN6924
Synonym: (2S,3S)-6,7-dihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-2-[(1S,2R,3R)-1,2,3,4-tetrahydroxybutyl]-3-{2,3,4-trihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-6-oxo-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]cyclohexa-1,4-dien-1,AHSYB
Target: Others
(-)-Butin
TN1461
Synonym: Butin
Target: Akt, PI3K, Nrf2
Phlorizin dihydrate
T2S2003
Synonym: Phloridzin dihydrate
Target: Others
Galactinol
T8177
Synonym:
Target: Others
Curculigoside
T6S1966
Synonym: Curculigoside A
Target: Antioxidant, NF-κB, JAK, STAT
nerolidol
T2S2172
Synonym: (±)-Nerolidol,Peruviol
Target: Others, Endogenous Metabolite, Antibacterial, Parasite, Antifungal
Eclalbasaponin I
TN1600
Synonym:
Target: Others
8-Hydroxyguanine
T19165
Synonym: 8 Hydroxyguanine,7,8-dihydro-8-oxoguanine,2-Amino-6,8-dihydroxypurine
Target: Endogenous Metabolite
4-hydroxyphenyl acetate
T8704
Synonym:
Target: Nrf2
Narcissin
T6S1768
Synonym: Isorhamnetin 3-Rutinoside,Narcissoside
Target: Antioxidant
Chlorogenic Acid
T2805
Synonym: NSC-407296,3-O-Caffeoylquinic acid,Heriguard
Target: Others, Influenza Virus, Reactive Oxygen Species, HIF/HIF Prolyl-Hydroxylase, Endogenous Metabolite, Antibacterial
Oxysophoridine
T2S1008
Synonym: Sophoridine N-oxide
Target: Apoptosis, Antioxidant

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-04460 OXSR1 Protein, Human, Recombinant (GST) Human Baculovirus-Insect Cells
Oxidative stress-responsive 1 protein (OXSR1), also known as Serine/threonine-protein kinase OSR1, is a member of the Ser/Thr protein kinase family of proteins. OXSR1 regulates downstream kinases in response to environme...
TMPH-00359 AlkB Protein, Caulobacter vibrioides, Recombinant (His & Myc) Caulobacter vibrioides E. coli
Dioxygenase that repairs alkylated DNA and RNA containing 3-methylcytosine or 1-methyladenine by oxidative demethylation. Has highest activity towards 3-methylcytosine. Has lower activity towards alkylated DNA containing...
TMPH-00577 AlkB Protein, E. coli, Recombinant (His & Myc & SUMO) E. coli E. coli
Dioxygenase that repairs alkylated DNA and RNA containing 3-methylcytosine or 1-methyladenine by oxidative demethylation. Has highest activity towards 3-methylcytosine. Has lower activity towards alkylated DNA containing...
TMPY-00541 LON PROTEASE Protein, E. coli, Recombinant (His) E. coli E. coli
Lon protease, an ATP-dependent mitochondrial protease, is important in mitochondrial protein maintenance. Lon protease is a multifunctional enzyme, and its functions include the degradation of damaged proteins and natura...
TMPY-01403 VNN1 Protein, Human, Recombinant (His) Human HEK293
Pantetheinase, also known as Pantetheine hydrolase, Vascular non-inflammatory molecule 1, Vanin-1, and VNN1, is a cell membrane protein which belongs to the CN hydrolase family and BTD/VNN subfamily. Vanin-1 contains one...
TMPH-02681 GPX7 Protein, Mouse, Recombinant (His & Myc) Mouse E. coli
It protects esophageal epithelia from hydrogen peroxide-induced oxidative stress. It suppresses acidic bile acid-induced reactive oxigen species (ROS) and protects against oxidative DNA damage and double-strand breaks.
TMPH-01397 LANCL1 Protein, Human, Recombinant (His & Myc) Human E. coli
Functions as glutathione transferase. Catalyzes conjugation of the glutathione (GSH) to artificial substrates 1-chloro-2,4-dinitrobenzene (CDNB) and p-nitrophenyl acetate. Mitigates neuronal oxidative stress during norma...
TMPH-00641 YTFE Protein, E. coli, Recombinant (GST) E. coli E. coli
Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions.
TMPY-02299 ALDH3A1 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
Aldehyde dehydrogenase 3A1 (ALDH3A1) is a metabolic enzyme that catalyzes the oxidation of various aldehydes. Certain types of epithelial tissues in mammals, especially those continually exposed to environmental stress (...
TMPH-03443 GPX2 Protein, S. cerevisiae, Recombinant (His & Myc) Saccharomyces cerevisiae E. coli
Glutathione peroxidase-like protein that protects cells from phospholipid hydroperoxides and nonphospholipid peroxides during oxidative stress. Plays an important role in the oxidative stress-induced response in the pres...
TMPH-03275 Cytoglobin Protein, Rat, Recombinant (His & Myc) Rat E. coli
May have a protective function during conditions of oxidative stress. May be involved in intracellular oxygen storage or transfer. Plays a role in the development of liver fibrosis. Has a peroxidase activity.
TMPY-02043 PARK7/DJ-1 Protein, Human, Recombinant (His) Human E. coli
Parkinson's disease locus DJ-1 (PARK7) is a differentially expressed transcript. DJ-1 plays a physiologic role in protection of erythroid cells from oxidant damage, a function unmasked in the context of oxidative stress....
TMPH-02863 LOX Protein, Mouse, Recombinant (His & Myc) Mouse Baculovirus
Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. Regulator of Ras expression. May play a role in tumor suppression. Plays a role in t...
TMPH-01553 GBP2 Protein, Human, Recombinant (E. coli, His) Human E. coli
Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions, but the major reaction product is GDP. Exhibits antiviral activity against influenza virus. Promotes oxidative killing and delivers antimicrobial peptides to aut...
TMPH-01296 GPX5 Protein, Human, Recombinant (GST & His) Human E. coli
Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective syste...
TMPH-00773 RuBisCO large subunit Protein, Glycine max, Recombinant (His & SUMO) Glycine max E. coli
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration pro...
TMPK-00077 EPO/Erythropoietin Protein, Human, Recombinant Human HEK293
Erythropoietin (EPO) is a circulating hormone conventionally considered to be responsible for erythropoiesis. In addition to facilitating red blood cell production, EPO has pluripotent potential, such as for cognition im...
TMPH-03054 Asp f3 Protein, Neosartorya fumigata, Recombinant (His & SUMO) Neosartorya fumigata E. coli
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxide...
TMPH-02903 PON1 Protein, Mouse, Recombinant Mouse E. coli
Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediate...
TMPY-00089 TMIGD1 Protein, Human, Recombinant (His) Human HEK293
The transmembrane and immunoglobulin domain-containing 1 (TMIGD1) is a novel tumor suppressor that is highly expressed in normal renal tubular epithelial cells, but it is downregulated in human renal cancer. TMIGD1 is a ...
TMPY-04073 MRPL44 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
MRPL44 (Mitochondrial Ribosomal Protein L44) is a Protein Coding gene. MRPL44 encodes a protein in the large subunit of the mitochondrial ribosome and is suggested to locate near the tunnel exit of the yeast mitochondria...
TMPH-00794 Dps Protein, Helicobacter pylori, Recombinant (His & SUMO) Helicobacter pylori E. coli
Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical produ...
TMPY-04872 TMIGD1 Protein, Human, Recombinant (mFc) Human HEK293
The transmembrane and immunoglobulin domain-containing 1 (TMIGD1) is a novel tumor suppressor that is highly expressed in normal renal tubular epithelial cells, but it is downregulated in human renal cancer. TMIGD1 is a ...
TMPH-00072 2-Cys Prx A Protein, Arabidopsis thaliana, Recombinant (His) Arabidopsis thaliana Yeast
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxide...
TMPH-03721 IbpA Protein, Yersinia pestis bv. Antiqua, Recombinant (His) Yersinia pestis E. coli
Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the Ibp...
TMPH-02199 TXNRD2 Protein, Human, Recombinant (His) Human E. coli
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxide...
TMPH-02102 PON1 Protein, Human, Recombinant (GST) Human E. coli
Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediate...
TMPH-02875 ROMO1 Protein, Mouse, Recombinant (His) Mouse in vitro E. coli expression system
Has antibacterial activity against a variety of bacteria including S.aureus, P.aeruginosa and M.tuberculosis. Acts by inducing bacterial membrane breakage.; Induces production of reactive oxygen species (ROS) which are n...
TMPH-02153 Sulfiredoxin-1 Protein, Human, Recombinant (His & Myc) Human E. coli
Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4. Does not act on PRDX5 or PRDX6. May catalyze the reduct...
TMPJ-01248 Cytoglobin/CYGB Protein, Human, Recombinant (His) Human E. coli
Cytoglobin is a ubiquitously globin protein that belongs to the globin family. The highest expressed in heart, stomach, bladder and small intestine. CYGB acts a protector under conditions of oxidative stress. CYGB may be...
TMPH-00093 GAPC1, cytosolic Protein, Arabidopsis thaliana, Recombinant (His & Myc) Arabidopsis thaliana E. coli
Key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Essential for the maintenance of cellular ATP levels and carboh...
TMPJ-00982 DHS Protein, Human, Recombinant (His) Human E. coli
Human Deoxyhypusine Synthase (DHS) is vital for the first step of hypusine biosynthesis. DHS catalyzes the NAD-dependent oxidative cleavage of spermidine, the subsequent transfer of the butylamine moiety of spermidine to...
TMPH-02104 Sestrin-3/SESN3 Protein, Human, Recombinant (His & Myc) Human E. coli
May function as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway. May also regulate the insulin-receptor signaling pathway through activation of TORC2. This metabolic regulator may al...
TMPJ-00380 AOC3 Protein, Human, Recombinant (His) Human Human Cells
Vascular adhesion protein-1(VAP-1) is a copper amine oxidase with a topaquinone cofactor.VAP-1 is a type II integral membrane protein, but a soluble form of the enzyme is present in human serum, and its level increases i...
TMPJ-00720 TXNDC12 Protein, Human, Recombinant (His) Human Human Cells
Thioredoxin Domain-Containing Protein 12 belongs to the thioredoxin superfamily. In this family, proteins possess a thioredoxin fold with a consensus active-site sequence (CxxC) and have roles in redox regulation, defens...
TMPH-03460 ERG26 Protein, S. cerevisiae, Recombinant (His & Myc) SVG-Saccharomyces cerevisiae E. coli
Essential enzyme in the ergosterol biosynthetic pathway. Part of a 3 enzyme system that catalyzes the sequential removal of the 2 methyl groups at the sterol C-4 position, converting 4,4-dimethylzymosterol to zymosterol....
TMPJ-01076 FKBP4 Protein, Human, Recombinant (His) Human E. coli
FKBP4 act as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. FKBP4 may play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone recepto...
TMPH-02618 CYP2E1 Protein, Mouse, Recombinant (His) Mouse E. coli
A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electr...
TMPH-02997 Dps Protein, Mycobacterium smegmatis, Recombinant (His & SUMO) Mycobacterium smegmatis E. coli
Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical produ...
TMPK-00285 ANGPTL3 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
ANGPTL3 is a secreted glycoprotein that is structurally related to the angiopoietins. Mature human ANGPTL3 contains an N-terminal coiled coil domain and a C‑terminal fibrinogen-like domain. ANGPTL3 is expressed in the li...
TMPY-02544 FANCA Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
FANCA is one of the six known Fanconi anemia gene products (FANCA, FANCC, FANCD2, FANCE, FANCF, and FANCG proteins). Fanconi anemia (FA) is a genetic disorder predisposing to aplastic anemia and cancer characterized by h...
TMPY-01770 HAO1 Protein, Human, Recombinant (His) Human E. coli
Hydroxyacid oxidase 1, also known as Glycolate oxidase, HAO1, and GOX1, is a member of the FMN-dependent alpha-hydroxy acid dehydrogenase family. HAO1 / GOX1 has 2-hydroxyacid oxidase activity. It is most active on the 2...
TMPY-02201 Peroxiredoxin 6 Protein, Human, Recombinant (His) Human E. coli
PRDX6, a member of antioxidant protein superfamily, plays an important role in oxidative stress, catabolism of lipids and phospholipid lipisomes. Peroxiredoxin 6 (PRDX6) is involved in redox regulation of the cell and is...
TMPH-02687 Granzyme A/GZMA Protein, Mouse, Recombinant (His) Mouse E. coli
Abundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent pyroptosis when delivered into the target cell through the immunological synapse. It cleaves after Lys or ...
TMPH-01761 Neuroglobin Protein, Human, Recombinant (His & SUMO) Human E. coli
Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Not capable of penetrating cell membranes. The deoxygenated form exhi...
TMPJ-00379 AOC3 Protein, Human, Recombinant (hFc) Human Human Cells
Membrane primary amine oxidase(AOC3), also known as vascular adhesion protein (VAP-1) and HPAO, this protein is a member of the semicarbazide-sensitive amine oxidase (SSAO) family. VAP-1 is a type 1 membrane-bound glycop...
TMPY-02401 Tyrosine Hydroxylase Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
Tyrosine hydroxylase (TH) is a rate-limiting enzyme in catecholamine synthesis. Tyrosine hydroxylase activity is modulated by protein-protein interactions with enzymes in the same pathway or the tetrahydrobiopterin pathw...
TMPY-02587 Tyrosine Hydroxylase Protein, Mouse, Recombinant (His) Mouse Baculovirus-Insect Cells
Tyrosine hydroxylase (TH) is a rate-limiting enzyme in catecholamine synthesis. Tyrosine hydroxylase activity is modulated by protein-protein interactions with enzymes in the same pathway or the tetrahydrobiopterin pathw...
TMPY-02271 TRXR1/TXNRD1 Protein, Human, Recombinant (aa 161-647, His) Human E. coli
Thioredoxin reductase 1 (TXNRD1) which is a selenocysteine-containing protein is overexpressed in many malignancies. TXNRD1 plays a key role in regulating cell growth and transformation, and protects cells against oxidat...
TMPH-02661 Frataxin/FXN Protein, Mouse, Recombinant (E. coli, His) Mouse E. coli
Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress thr...
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OXSR1 Protein, Human, Recombinant (GST)
TMPY-04460
Species: Human
Expression System: Baculovirus-Insect Cells
AlkB Protein, Caulobacter vibrioides, Recombinant (His & Myc)
TMPH-00359
Species: Caulobacter vibrioides
Expression System: E. coli
AlkB Protein, E. coli, Recombinant (His & Myc & SUMO)
TMPH-00577
Species: E. coli
Expression System: E. coli
LON PROTEASE Protein, E. coli, Recombinant (His)
TMPY-00541
Species: E. coli
Expression System: E. coli
VNN1 Protein, Human, Recombinant (His)
TMPY-01403
Species: Human
Expression System: HEK293
GPX7 Protein, Mouse, Recombinant (His & Myc)
TMPH-02681
Species: Mouse
Expression System: E. coli
LANCL1 Protein, Human, Recombinant (His & Myc)
TMPH-01397
Species: Human
Expression System: E. coli
YTFE Protein, E. coli, Recombinant (GST)
TMPH-00641
Species: E. coli
Expression System: E. coli
ALDH3A1 Protein, Human, Recombinant (His)
TMPY-02299
Species: Human
Expression System: Baculovirus-Insect Cells
GPX2 Protein, S. cerevisiae, Recombinant (His & Myc)
TMPH-03443
Species: Saccharomyces cerevisiae
Expression System: E. coli
Cytoglobin Protein, Rat, Recombinant (His & Myc)
TMPH-03275
Species: Rat
Expression System: E. coli
PARK7/DJ-1 Protein, Human, Recombinant (His)
TMPY-02043
Species: Human
Expression System: E. coli
LOX Protein, Mouse, Recombinant (His & Myc)
TMPH-02863
Species: Mouse
Expression System: Baculovirus
GBP2 Protein, Human, Recombinant (E. coli, His)
TMPH-01553
Species: Human
Expression System: E. coli
GPX5 Protein, Human, Recombinant (GST & His)
TMPH-01296
Species: Human
Expression System: E. coli
RuBisCO large subunit Protein, Glycine max, Recombinant (His & SUMO)
TMPH-00773
Species: Glycine max
Expression System: E. coli
EPO/Erythropoietin Protein, Human, Recombinant
TMPK-00077
Species: Human
Expression System: HEK293
Asp f3 Protein, Neosartorya fumigata, Recombinant (His & SUMO)
TMPH-03054
Species: Neosartorya fumigata
Expression System: E. coli
PON1 Protein, Mouse, Recombinant
TMPH-02903
Species: Mouse
Expression System: E. coli
TMIGD1 Protein, Human, Recombinant (His)
TMPY-00089
Species: Human
Expression System: HEK293
MRPL44 Protein, Human, Recombinant (His)
TMPY-04073
Species: Human
Expression System: Baculovirus-Insect Cells
Dps Protein, Helicobacter pylori, Recombinant (His & SUMO)
TMPH-00794
Species: Helicobacter pylori
Expression System: E. coli
TMIGD1 Protein, Human, Recombinant (mFc)
TMPY-04872
Species: Human
Expression System: HEK293
2-Cys Prx A Protein, Arabidopsis thaliana, Recombinant (His)
TMPH-00072
Species: Arabidopsis thaliana
Expression System: Yeast
IbpA Protein, Yersinia pestis bv. Antiqua, Recombinant (His)
TMPH-03721
Species: Yersinia pestis
Expression System: E. coli
TXNRD2 Protein, Human, Recombinant (His)
TMPH-02199
Species: Human
Expression System: E. coli
PON1 Protein, Human, Recombinant (GST)
TMPH-02102
Species: Human
Expression System: E. coli
ROMO1 Protein, Mouse, Recombinant (His)
TMPH-02875
Species: Mouse
Expression System: in vitro E. coli expression system
Sulfiredoxin-1 Protein, Human, Recombinant (His & Myc)
TMPH-02153
Species: Human
Expression System: E. coli
Cytoglobin/CYGB Protein, Human, Recombinant (His)
TMPJ-01248
Species: Human
Expression System: E. coli
GAPC1, cytosolic Protein, Arabidopsis thaliana, Recombinant (His & Myc)
TMPH-00093
Species: Arabidopsis thaliana
Expression System: E. coli
DHS Protein, Human, Recombinant (His)
TMPJ-00982
Species: Human
Expression System: E. coli
Sestrin-3/SESN3 Protein, Human, Recombinant (His & Myc)
TMPH-02104
Species: Human
Expression System: E. coli
AOC3 Protein, Human, Recombinant (His)
TMPJ-00380
Species: Human
Expression System: Human Cells
TXNDC12 Protein, Human, Recombinant (His)
TMPJ-00720
Species: Human
Expression System: Human Cells
ERG26 Protein, S. cerevisiae, Recombinant (His & Myc)
TMPH-03460
Species: SVG-Saccharomyces cerevisiae
Expression System: E. coli
FKBP4 Protein, Human, Recombinant (His)
TMPJ-01076
Species: Human
Expression System: E. coli
CYP2E1 Protein, Mouse, Recombinant (His)
TMPH-02618
Species: Mouse
Expression System: E. coli
Dps Protein, Mycobacterium smegmatis, Recombinant (His & SUMO)
TMPH-02997
Species: Mycobacterium smegmatis
Expression System: E. coli
ANGPTL3 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00285
Species: Human
Expression System: HEK293
FANCA Protein, Human, Recombinant (His)
TMPY-02544
Species: Human
Expression System: Baculovirus-Insect Cells
HAO1 Protein, Human, Recombinant (His)
TMPY-01770
Species: Human
Expression System: E. coli
Peroxiredoxin 6 Protein, Human, Recombinant (His)
TMPY-02201
Species: Human
Expression System: E. coli
Granzyme A/GZMA Protein, Mouse, Recombinant (His)
TMPH-02687
Species: Mouse
Expression System: E. coli
Neuroglobin Protein, Human, Recombinant (His & SUMO)
TMPH-01761
Species: Human
Expression System: E. coli
AOC3 Protein, Human, Recombinant (hFc)
TMPJ-00379
Species: Human
Expression System: Human Cells
Tyrosine Hydroxylase Protein, Human, Recombinant (His)
TMPY-02401
Species: Human
Expression System: Baculovirus-Insect Cells
Tyrosine Hydroxylase Protein, Mouse, Recombinant (His)
TMPY-02587
Species: Mouse
Expression System: Baculovirus-Insect Cells
TRXR1/TXNRD1 Protein, Human, Recombinant (aa 161-647, His)
TMPY-02271
Species: Human
Expression System: E. coli
Frataxin/FXN Protein, Mouse, Recombinant (E. coli, His)
TMPH-02661
Species: Mouse
Expression System: E. coli
Cat No. Product Name
L2910 Antioxidant Compound Library

1330 compounds
Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species (ROS) and a biological system's ability to readily detoxify the reactive intermediates or repair the resulting damage. ...
L5300 Mitochondria-Targeted Compound Library

830 compounds
A unique collection of 830 promising or approved mitochondria-targeted compounds including Idebenone, the only approved drug targeting mitochondria, for research in mitochondrial medicine;
L6110 Alkaloid Natural Product Library

468 compounds
A unique collection of 468 natural alkaloids can be used for high throughput and high content screening;
L6140 Saccharide and Glycoside Natural Product Library

364 compounds
A unique collection of 364 saccharides and glycosides compounds can be used for HTS and HCS;
L2520 Glycometabolism Compound Library

708 compounds
708 glycometabolism-related comounds, can be used for HTS and HCT;
L6120 Flavonoid Natural Product Library

477 compounds
A unique collection of 477 flavonoids can be used for high throughput and high content screening;
L9840 Anti-Alzheimer's Disease Compound Library

1040 compounds
A unique collection of 1040 compounds with anti-AD activities or acting on main drug targets of AD can be used for HTS and HCS.
TargetMol