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Synonyms: 3′,6-Disinapoyl sucrose


| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 2 mg | $38 | - | In Stock | |
| 5 mg | $60 | - | In Stock | |
| 10 mg | $98 | - | In Stock | |
| 25 mg | $162 | - | In Stock | |
| 50 mg | $238 | - | In Stock | |
| 100 mg | $357 | - | In Stock | |
| 1 mL x 10 mM (in DMSO) | $98 | - | In Stock |
| Description | 3′,6-Disinapoylsucrose exerts anti-aging effects via modification of telomeres, SIRT1/p53/p21 pathway, oxidative stress and autophagy. 3′,6-Disinapoylsucroseis studied in cellular aging and stress-response research models focusing on telomere-associated signaling, SIRT1/p53/p21 axis modulation, oxidative stress regulation, and autophagy pathways. 3′,6-Disinapoylsucrose is therefore applied in experimental gerontology and cellular homeostasis research systems to evaluate molecular markers of senescence, stress adaptation, and autophagy flux in in vitro and in vivo model systems. |
| In vivo | Method:APP/PS1 transgenic mice were used to evaluate the neuroprotective effects of 3,6'-disinapoyl sucrose (3′,6-Disinapoylsucrose (DISS)) using behavioral tests, hippocampal histology (Nissl, TUNEL), ELISA for inflammatory markers, and Western blot for signaling proteins. Result:3′,6-Disinapoylsucrose (DISS) significantly improved learning and memory deficits in APP/PS1 mice. It reduced neuronal apoptosis (decreased Bax/Bcl-2 ratio) and restored inflammatory cytokine levels (IL-2, TNF-α, IL-1β, IL-6). High-dose 3′,6-Disinapoylsucrose (DISS) increased CREB and BDNF expression in the hippocampus. |
| Synonyms | 3′,6-Disinapoyl sucrose |
| Molecular Weight | 754.69 |
| Formula | C34H42O19 |
| Cas No. | 76656-80-9 |
| Smiles | O([C@@]1(CO)[C@@H](OC(C=CC2=CC(OC)=C(O)C(OC)=C2)=O)[C@H](O)[C@@H](CO)O1)[C@H]3O[C@H](COC(C=CC4=CC(OC)=C(O)C(OC)=C4)=O)[C@@H](O)[C@H](O)[C@H]3O |
| Relative Density. | no data available |
| Storage | Keep away from moisture,Keep away from direct sunlight, Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 µL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 µL Tween 80 and mix well until fully clarified.
3) Add 450 µL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
| Size | Quantity | Unit Price | Amount | Operation |
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