AChR

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T0018	Procainamide hydrochloride	Procainamide Hydrochloride is the hydrochloride salt form of procainamide, an amide derivative exhibiting class 1A antiarrhythmic property and analog of procain...
T0024	Primidone	Primidone is an anticonvulsant of the pyrimidinedione class.
T0051	Urethane	Urethane was an antineoplastic agent .Now is used for other medicinal purposes.
T0052	Strychnine	An alkaloid found in the seeds of STRYCHNOS NUX-VOMICA. It is a competitive antagonist at glycine receptors and thus a convulsant. It has been used as an analep...
T0064	Adenine	Adenine, a purine derivative, is a nucleobase with various roles in biochemistry including cellular respiration, in the form of both the energy-rich ATP and NA...
T0072	Adiphenine hydrochloride	Adiphenine hydrochloride, a nicotinic receptor inhibitor, can be used as an antispasmodic drug.
T0074L	Chlorprothixene hydrochloride	Chlorprothixene brings strong blocking effects by blocking the 5-HT2 D1, D2, D3, histamine H1, muscarinic and alpha1 adrenergic receptors. Chlorprothixene is a ...
T0086	Galanthamine HBr	Galanthamine hydrobromide, a long-acting and centrally active AChE inhibitor (IC50:410 nM), is an allosteric potentiator at neuronal nicotinic ACh receptors.
T0098	Ipratropium bromide monohydrate	Ipratropium bromide is a muscarinic antagonist structurally related to ATROPINE but often considered safer and more effective for inhalation use. It is used for...
T0099	Tolterodine tartrate	Tolterodine Tartrate(PNU-200583E; Kabi-2234) is a potent antagonist for muscarinic receptor. It show selectivity for the urinary bladder and salivary glands in...
T0103	Dipivefrin hydrochloride	Dipivefrin that is available as an ophthalmic solution is a prodrug of adrenaline, which is used to treat glaucoma.
T0105	Carbachol	Carbamoylcholine chloride is used to study responses mediated by nAChR and mAChR, including smooth muscle contraction, gut motility, and neuronal signaling.
T0111	Solifenacin succinate	Solifenacin succinate is a quinuclidine and tetrahydroisoquinoline derivative and selective M3 MUSCARINIC ANTAGONIST. It is used as a UROLOGIC AGENT in the trea...
T0113	Mebhydrolin napadisylate	Mebhydrolin (napadisylate) is an antihistamine used to relieve allergic symptoms caused by histamine release, including nasal allergies and allergic dermatosis.
T0130	Physostigmine Salicylate	Physostigmine, a parasympathomimetic alkaloid, is a reversible cholinesterase inhibitor. It extracts from the Calabar bean.
T0156	Rocuronium bromide	Rocuronium is a muscle relaxant or aminosteroid non-depolarizing neuromuscular blocker. During surgery or mechanical ventilation, it is used to facilitate endo...
T0162	Quetiapin	Quetiapine is used for the therapy of schizophrenia, and for the treatment of acute manic episodes associated with bipolar I disorder. The mechanism of quetiapi...
T0166	Pancuronium bromide	Pancuronium dibromide, a competitive AChR antagonist (IC50 = 5.5 nM), acts as a skeletal muscle relaxant. Pancuronium dibromide blocking neuromuscular transmis...
T0172	Maprotiline hydrochloride	Maprotiline hydrochloride is a bridged-ring tetracyclic antidepressant that is both mechanistically and functionally similar to the tricyclic antidepressants, i...
T0177	Homatropine Bromide	Homatropine Hydrobromide is the hydrobromide salt form of homatropine, a synthetic tertiary amine alkaloid with antimuscarinic properties. Homatropine, a compet...
T0229	Rivastigmine	Rivastigmine is a Cholinesterase Inhibitor, used for therapy of Alzheimer disease.
T0236	Azatadine Maleate	Azatadine dimaleate is an inhibitor for histamine（IC50=6.5 nM） and cholinergic（IC50=10 nM）.
T0253	Methscopolamine	Methscopolamine (Pamine), as a natural plant alkaloid, is a muscarinic acetylcholine receptor blocker.
T0262	Dextromethorphan HBr monohydrate	Methyl analog of DEXTRORPHAN that shows high-affinity binding to some areas of the brain, including the medullary cough center. This compound is an NMDA recepto...
T0268	Lobeline hydrochloride	Lobeline hydrochloride is a nicotinic receptor agonist, acting as an effective antagonist at both α4β2 and α3β2 neuronal nicotinic receptor subtypes.
T0269	Dichlorisone Acetate	Dichlorisone Acetate is a synthetic glucocorticoid corticosteroid with anti-inflammatory activity.
T0287	Hexamethonium Bromide	Hexamethonium Bromide, a specific antagonist of neuronal-type nicotinic AChR in ganglia, is poorly absorbed from the gastrointestinal tract and does not cross t...
T0296	Pempidine	Pempidine is a nicotinic antagonist, has been used as a ganglionic blocker in the treatment of hypertension.
T0302	Triflupromazine hydrochloride	Triflupromazine hydrochloride, an antipsychotic medication, is Dopamine D1/D2 receptor antagonists.
T0338	Minaprine dihydrochloride	Minaprine is a reversible inhibitor of MAO-A, used in the treatment of various depressive states.
T0364	Dibucaine	Dibucaine, a local anesthetic of the amide type, is now usually used for surface anesthesia.
T0364L	Dibucaine hydrochloride	Dibucaine hydrochloride, a long-acting local amide anestheticsis, is usually used for surface anesthesia.
T0375	Atropine	Atropine Sulfate is the sulfate salt of atropine, a naturally-occurring alkaloid isolated from the plant Atropa belladonna. Atropine functions as a sympathetic,...
T0375L	Atropine sulfate monohydrate	Atropine sulfate monohydrate, the sulfate salt of atropine, is a competitive muscarinic acetylcholine receptor antagonist.
T0375L2	Atropine sulfate	Atropine sulfate is a competitive antagonist for muscarinic acetylcholine receptor.
T0401	Benzethonium chloride	Benzethonium is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum antimicrobial properties.
T0427	Homatropine Methylbromide	Homatropine Methylbromide is the methyl bromide salt of homatropine, a synthetic tertiary amine alkaloid with antimuscarinic properties.
T0445	Promethazine	Tafluprost(AFP-168) is an analogue of anti-glaucoma prostaglandin (PG) .
T0455	Clozapine	Clozapine is a tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, and display...
T0479	Cytisine	Cytisine, an alkaloid, is found naturally in several plants.
T0594	Diphemanil mesylate	Diphemanil methylsulfate, a quaternary ammonium anticholinergic, binds muscarinic acetylcholine receptors and thus decreases secretory excretion of stomach acid...
T0625	Theobromine	3,7-Dimethylxanthine, a xanthine alkaloid, is used as a bronchodilator and as a vasodilator.
T0665	2,6-Dihydroxypurine	Xanthine is a product on the pathway of purine degradation. Xanthine is subsequently converted to uric acid by the action of the Xanthine oxidase enzyme. Xanthi...
T0684	Ribavirin	Ribavirin is a synthetic nucleoside analog of ribofuranose with activity against hepatitis C virus and other RNA viruses.
T0703	Flavoxate hydrochloride	Flavoxate Hydrochloride(DW-61 Hydrochloride), a muscarinic AChR antagonist, is used in the therapy of various urinary syndromes and as an antispasmodic.
T0713	Drofenine hydrochloride	Drofenine hydrochloride is an effective competitive inhibitor of BChE (Ki value: 3 uM).
T0716	Molindone hydrochloride	Molindone hydrochloride is an indole derivative effective in schizophrenia and other psychoses by blocking the effects of dopamine in the brain.
T0720	Gallamine triethiodide	Gallamine Triethiodide, a synthetic inhibiting drug, is nondepolarizing.
T0731	Delphene	DEET is the most general active composition in insect repellents.
T0765	4-Methylpyrazole	Fomepizole is used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning. Fomepizole is a competitive inhibitor of alcohol dehydrogenas...

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