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OLIG2

OLIG2 (Oligodendrocyte Transcription Factor 2) is a basic helix-loop-helix (bHLH) transcription factor that is expressed primarily in the central nervous system and regulates the development and differentiation of glial cells.OLIG2 plays a critical role in a variety of processes, including astrocyte maturation, medulloblastoma stem cell fate transition, and oligodendrocyte formation.

CT-179
T700071996636-69-1
CT-179 is a potent and selective inhibitor of oligodendrocyte transcription factor 2 (OLIG2), reduces tumor cell proliferation and induces apoptosis, and enhances efficacy when used in combination with radiotherapy and other agents, showing potential in the treatment of medulloblastoma and glioblastoma.
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