muscle — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T1889	CP-640186	CP 640186	Acetyl-CoA Carboxylase
	CP-640186 is an isozyme-nonselective Acetyl-CoA carboxylase (ACCase) inhibitor. The IC50s of CP-640186(CP 640186) is 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively.		Acetyl-CoA Carboxylase
T3622	CP-640186 hydrochloride	CP 640186 HCl	Acetyl-CoA Carboxylase
	CP-640186 hydrochloride (CP 640186 HCl) is an isozyme-nonselective acetyl-CoA carboxylase (ACC) inhibitor, including rat liver ACC1 (IC50: 53 nM) and rat skeletal muscle ACC2 (IC50: 61 nM); with higher metabolic stabilit...		Acetyl-CoA Carboxylase
T6792	BQ-123	BQ123	Endothelin Receptor
	BQ-123 is a selective endothelin A receptor (ETA) antagonist with IC50 of 7.3 nM. Phase 2.		Endothelin Receptor
T11831	LDN-27219		Others
	LDN-27219 is a potent hTGase inhibitor with IC50 of 0.6 uM.		Others
T8760	NNMTi	5-Amino-1-methylquinolinium	Others
	NNMTi (5-Amino-1-methylquinolinium) is a substrate site-targeting, selective nicotinamide N-methyltransferase (NNMT) inhibitor (IC50 = 1.2 μM; 50 μM SAM, 100 μM NCA) that reduces 3T3-L1 lipogenesis (EC50 = 30μM) and adip...		Others
T3563	Lvguidingan		Others
	Lvguidingan is an Anticonvulsant agent.		Others
T8452	Dantrolene		Others
	Dantrolene is a postsynaptic muscle relaxant by inhibiting Ca2+ ions release from sarcoplasmic reticulum stores by antagonizing ryanodine receptors.		Others
T8242	Sabinene		Others
	Sabinene is a natural product that has antifungal and anti-inflammatory properties		Others
T2S0820	Karanjin		Apoptosis , AMPK
	Karanjin is a flavonoid obtained from the seeds of the karanja tree.Karanjin induces GLUT4 translocation in skeletal muscle cells by increasing AMPK activity. Karanjin can induce cancer cell death through cell cycle arre...		Apoptosis , AMPK
T1431	Khellin	Amicardine,Methafrone,Visammin	EGFR , Others
	Khellin (Methafrone) is a vasodilator that also has bronchodilatory action.		EGFR , Others
T5458	Darusentan	Lu-135252	Endothelin Receptor
	Darusentan (Lu-135252) is a potent inhibitor of endothelin signaling and function in both large and small arteries		Endothelin Receptor
T23322	SB 452533		TRP/TRPV Channel
	SB 452533 is an antagonist of the vanilloid receptor 1(pKb: 7.8).		TRP/TRPV Channel
T22459	Xanthinol Nicotinate	Angioamin,Complamin	Others
	Xanthinol Nicotinate (Complamin) is a potent vasodilator that can easily enter the cell and causes an increase in glucose metabolism resulting in an increased energy.		Others
TN1084	1,3,5,8-Tetrahydroxyxanthone	Desmethylbellidifolin	Anti-infection
	1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin) is a natural xanthone extracted from Gentianella acuta. 1,3,5,8-Tetrahydroxyxanthone has antispasmodic effect and anti-inflammatory activity. Dimethylbellidifolin show...		Anti-infection
T22967	MEDICA16	MEDICA 16	GPR , Others , ATP Citrate Lyase
	MEDICA16 is a selective agonist for GPR40 as well as a partial agonist for GPR120. MEDICA16, an ATP-citrate lyase inhibitor, significantly reduces intracellular TG content in gastrocnemius muscle with an increase in insu...		GPR , Others , ATP Citrate Lyase
T1594	Vecuronium bromide	ORG NC 45	AChR
	Vecuronium bromide (ORG NC 45) is a synthetic, intermediate-acting mono-quaternary steroid and non-depolarizing neuromuscular blocking agent, with muscle relaxant activity.		AChR
T0145	Felodipine	CGH-869	Calcium Channel , Autophagy
	Felodipine (CGH-869) is a longlasting 1, 4-dihydropyridine calcium channel repressor.		Calcium Channel , Autophagy
T1072	Loxeen	Pridinol methanesulfonate	AChR
	Loxeen (Pridinol methanesulfonate) is used as an anticholinergic and as an antiparkinsonian agent.		AChR
T10492	BD-AcAc 2	Ketone Ester	Reactive Oxygen Species
	BD-AcAc 2 (Ketone Ester) is a ketone monoester and can be used as a source of oral nutritional ketones. BD-AcAc 2 can elevate plasma levels of acetoacetate and β-hydroxybutyrate, blood Na+, blood glucose levels and blood...		Reactive Oxygen Species
T22371	Mivacurium dichloride	Mivacurium chloride	AChR
	Mivacurium dichloride (Mivacurium chloride) is a non-depolarising, rapid neuromuscular blocker of short duration, used therefore as anesthetic, to provide skeletal muscle relaxation in minor surgical operations, in emerg...		AChR