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Results for "

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  • Inhibitors & Agonists
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Ginsenoside F3
T382962025-50-7
Ginsenoside-F3 has immunoenhancing activity by regulating production and gene expression of type 1, type 2 cytokines in murine spleen cells. Ginsenoside-F3 enhances the NF-kappaB DNA binding activity induced by ConA in murine spleen cells (10 μM).
  • $36
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TargetMol | Citations Cited
F3-PEG8-RiboTAC
T210643
F3-PEG8-RiboTAC is a RiboTAC compound that specifically degrades the mRNA of the oncogene LGALS1. This compound can induce apoptosis (cell death) in tumor cells and inhibit their invasion. F3-PEG8-RiboTAC exhibits antitumor activity and is applicable in research on leukemia and triple-negative breast cancer. (RNase L ligand; RNA binder; Linker)
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Anti-F3/Factor III/Tissue Factor/CD142 Antibody
T9901A-1271
Anti-F3/Factor III/Tissue Factor/CD142 Antibody represents a highly specialized monoclonal antibody specifically engineered to target the human Tissue Factor (TF/CD142) with exceptional binding affinity. It effectively facilitates the measurable targeting of TF-expressing malignant cells across various preclinical experimental models to evaluate the delivery of cytotoxic payloads or the disruption of TF-mediated oncogenic signaling during strictly monitored laboratory observation periods and functional cell viability assays without compromising systemic coagulation homeostasis.
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    DSPE-PEG5000-F3
    TCL-01084
    DSPE-PEG5000-F3 consists of DSPE and the nucleolin-targeting peptide (F3) and is a PEGylated compound. The F3 peptide specifically binds to nucleolin on the cell surface, facilitating efficient transport from the cell surface to the nucleus. DSPE-PEG5000-F3 is applicable for drug delivery.
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    DSPE-PEG1000-F3
    TCL-01187
    DSPE-PEG1000-F3 is a PEG compound made from DSPE and a targeting peptide called nucleolin (F3). The F3 peptide can specifically bind to cell surface nucleolin, enabling efficient transport from the cell surface to the nucleus. DSPE-PEG1000-F3 is applicable in drug delivery.
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    DSPE-PEG2000-F3
    TCL-01188
    DSPE-PEG2000-F3 is a PEG compound composed of DSPE and the nucleolin-targeting peptide (F3). The F3 peptide can specifically bind to nucleolin on the cell surface, facilitating efficient transport from the cell surface to the nucleus. DSPE-PEG2000-F3 is applicable for drug delivery.
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    DSPE-PEG3400-F3
    TCL-01308
    DSPE-PEG3400-F3 is a PEG-modified compound composed of DSPE and the nucleolin-targeting peptide (F3). The F3 peptide has the ability to specifically bind to cell surface nucleolin and facilitate efficient transport from the cell surface to the nucleus. DSPE-PEG3400-F3 is applicable in drug delivery.
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    Ginsenoside F3 (Standard)
    TMSM-268262025-50-7
    Ginsenoside F3 (Standard) is a reference standard for research and analysis in studies involving Ginsenoside F3. Ginsenoside-F3 has immunoenhancing activity by regulating production and gene expression of type 1, type 2 cytokines in murine spleen cells. Ginsenoside-F3 enhances the NF-kappaB DNA binding activity induced by ConA in murine spleen cells (10 μM).
    • $743
    7-10 days
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    F3 peptide
    TP3694536971-53-6
    F3 peptide is a fragment of human high mobility group protein 2 (HMGB2) that specifically binds to nucleolin, expressed on the membranes of cancer cells, neovasculature, and endothelial cells. Serving as an effective ligand, F3 peptide enhances the druggability of macromolecular drugs or nanoparticles.
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    Osimertinib
    Mereletinib, AZD-9291
    T24901421373-65-0
    Osimertinib (AZD-9291) is an EGFR third-generation inhibitor that inhibits the T790M resistance mutation produced by second-generation EGFR inhibitors with irreversible and oral activity. Osimertinib has antitumor activity for the treatment of EGFR-mutated non-small-cell lung cancer.
    • $30
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    TargetMol | Inhibitor Hot
    TargetMol | Citations Cited
    Osimertinib mesylate
    Mereletinib mesylate, AZD-9291 mesylate
    T36341421373-66-1
    Osimertinib mesylate (AZD-9291 mesylate) is an EGFR third-generation inhibitor that inhibits the T790M resistance mutation produced by second-generation EGFR inhibitors with irreversible and oral activity. Osimertinib mesylate has antitumor activity for the treatment of EGFR-mutated non-small-cell lung cancer.
    • $45
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    TargetMol | Citations Cited
    Calcium glycerophosphate
    T6025427214-00-2
    Calcium glycerophosphate(CaGP) is an inhibitor of intestinal alkaline phosphatase F3. Calcium glycerophosphate can be a source of calcium and phosphorus in total parenteral nutrition solutions [1] [2].
    • $29
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    GNF-2
    GNF2
    T1817778270-11-4
    GNF-2 is a highly selective non-ATP competitive inhibitor of Bcr-Abl.
    • $41
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    TargetMol | Inhibitor Sale
    3'-F-3'-dA(Bz)-2'-phosphoramidite
    TNU12462127174-09-6
    3'-F-3'-dA(Bz)-2'-phosphoramidite is a fluoro-modified nucleoside derivative used as a nucleoside phosphoramidite.
    • Inquiry Price
    7-10 days
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    3'-F-3'-dG(iBu)-2'-phosphoramidite
    TNU13772080404-21-1
    3'-F-3'-dG(iBu)-2'-phosphoramidite is a Nucleoside Phosphoramidite.
    • Inquiry Price
    7-10 days
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    Prostaglandin F3α
    PGF3α
    T208716745-64-2
    Prostaglandin F3α (PGF3α) is a bioactive lipid mediator derived from eicosapentaenoic acid (EPA) with anticancer and anti-inflammatory properties. It serves as a substrate for ABCC4 with a Km of 12.1 μM. Additionally, Prostaglandin F3α (PGF3α) is utilized in diabetes research.
    • $170
    35 days
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    8-iso Prostaglandin F3α
    8-iso Prostaglandin F3α, 8-epi PGF3α
    T361647045-31-0
    8-iso PGF3α is an isoprostane produced from the free-radical peroxidation of EPA. While little is known about its biological activity, one report indicates it is inactive in a TP receptor-mediated assay of human platelet shape change, a test in which 8-iso PGF2α has an ED50 value of 1 uM. [1]
    • $997
    35 days
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    Tuxobertinib
    BDTX-189
    T90722414572-47-5
    Tuxobertinib (BDTX-189) is a potent and selective inhibitor of allosteric EGFR and HER2 oncogenic mutations, with KDs of 0.2, 0.76, 13, and 1.2 nM for EGFR, HER2, BLK, and RIPK2, respectively, and exhibits anticancer activity.
    • $34
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    Anti-Mouse IL-17A Antibody (17F3)
    T9901A-501
    Anti-Mouse IL-17A Antibody (17F3) is a mouse-derived IgG1, κ antibody inhibitor that targets mouse IL-17A.
    • $307
    2-4 weeks
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    Anti-Mouse IL-6 Antibody (MP5-20F3)
    T9901A-545
    Anti-Mouse IL-6 Antibody (MP5-20F3) is a monoclonal antibody against mouse IL-6, which can reshape the tumor microenvironment by blocking IL-6, inhibit the STAT3 pathway and enhance T cell infiltration, and is suitable for research on inflammatory and infectious diseases (such as malignant pleural effusion, MPE).
    • $254
    2-4 weeks
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    Anti-Mouse VISTA Antibody (13F3)
    T9901A-588
    Anti-MouseVISTAAntibody (13F3) is an IgG antibody inhibitor originating from American hamsters and targeting mouse VISTA.
    • $182
    2-4 weeks
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    (17E)-Prostaglandin F3α
    17-trans-PGF3α
    TYD-02764211100-24-2
    (17E)-Prostaglandin F3α (17-trans-PGF3α) is a double bond isomer of Prostaglandin F3α and is a potential metabolite of trans dietary fatty acids. This compound exhibits anti-inflammatory properties.
    • Inquiry Price
    10-14 weeks
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    3F8
    3F-8, 3F 8
    T22180159109-11-2In house
    3F8 is a selective GSK-3β inhibitor that can be used as a new tool and potential therapeutic candidate compound for GSK3-related diseases, and can be used in the study of neurological disorders and cancer.
    • $68
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    TargetMol | Inhibitor Sale
    3-O-Methyltagitinin F
    T126402
    3-O-Methyltagitinin F is a useful organic compound for research related to life sciences and the catalog number is T126402.
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