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Anti-FGFR4 Monoclonal Antibody (3F779)
(Synonyms: TKF, MGC20292, JTK2, CD334) Copy Product Info
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Synonyms: TKF, MGC20292, JTK2, CD334
Catalog No. TMAT-0918 Copy Product Info
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Anti-FGFR4 Monoclonal Antibody (3F779) is a Mouse antibody targeting FGFR4. Anti-FGFR4 Monoclonal Antibody (3F779) can be used in IHC.
Anti-FGFR4 Monoclonal Antibody
(3F779)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Stability & Storage
| Description | Anti-FGFR4 Monoclonal Antibody (3F779) is a Mouse antibody targeting FGFR4. Anti-FGFR4 Monoclonal Antibody (3F779) can be used in IHC. |
| Synonyms | TKF, MGC20292, JTK2, CD334 |
| Ig Type | IgG1 |
| Clone | 3F779 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC: 1/200-1/1000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | 1 mg/mL |
| Research Background | FGFR4 (fibroblast growth factor receptor 4) is part of a family of fibroblast growth factor receptors that mediate the biological functions of specific growth factors. There are four members of the FGF receptor family: FGFR-1 (flg), FGFR-2 (bek, KGFR), FGFR-3 and FGFR-4. Each receptor contains an extracellular ligand binding domain, a transmembrane domain and a cytoplasmic kinase domain. Following ligand binding and dimerization, the receptors are phosphorylated at specific tyrosine residues. These receptor proteins play a role in important processes such as cell division, regulating cell growth and maturation, formation of blood vessels, wound healing, and embryo development. Although specific functions of FGFR4 remain unclear, studies indicate that the gene is involved in muscle development and the maturation of bone cells in the skull. FGFR4 may also play a role in the development and maintenance of specialized cells (called foveal cones) in the light-sensitive layer (the retina) at the back of the eye. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of FGFR4 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | FGFR4 |
| Gene ID | |
| Protein Name | Fibroblast growth factor receptor 4 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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