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Anti-HLA-DPA1 Monoclonal Antibody (5F367)
(Synonyms: PLT1, HLASB, HLA-DPB1, HLA-DPA, HLA-DP1A, HLADP, DPA1, DP(W4), DP(W3)) Copy Product Info
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Synonyms: PLT1, HLASB, HLA-DPB1, HLA-DPA, HLA-DP1A, HLADP, DPA1, DP(W4), DP(W3)
Catalog No. TMAT-0895 Copy Product Info
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Anti-HLA-DPA1 Monoclonal Antibody (5F367) is a Mouse antibody targeting HLA-DPA1. Anti-HLA-DPA1 Monoclonal Antibody (5F367) can be used in WB,IHC,FCM.
Anti-HLA-DPA1 Monoclonal Antibody
(5F367)
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Product Introduction
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| Description | Anti-HLA-DPA1 Monoclonal Antibody (5F367) is a Mouse antibody targeting HLA-DPA1. Anti-HLA-DPA1 Monoclonal Antibody (5F367) can be used in WB,IHC,FCM. |
| Synonyms | PLT1, HLASB, HLA-DPB1, HLA-DPA, HLA-DP1A, HLADP, DPA1, DP(W4), DP(W3) |
| Ig Type | IgG2a |
| Clone | 5F367 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1/500-1/2000; IHC: 1/200-1/1000; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human HLA-DPA1 (AA: 29-209) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | HLA-DPA1 |
| Gene ID | |
| Protein Name | HLA class II histocompatibility antigen, DP alpha 1 chain |
| Uniprot ID |
| Molecular Weight | Theoretical: 29.3 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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