Shopping Cart
Remove All
Your shopping cart is currently empty
Anti-Glucokinase Antibody (5Q209) (Synonyms: MODY2, LGLK, HXKP, HKIV, HK4, HHF3, glucokinase (hexokinase 4...)
Catalog No. TMAY-01609 Copy Product Info
🥰Excellent
Anti-Glucokinase Antibody (5Q209) is a Mouse antibody targeting Glucokinase. Anti-Glucokinase Antibody (5Q209) can be used in ELISA.
Anti-Glucokinase Antibody (5Q209)
Copy Product Info🥰Excellent
Catalog No. TMAY-01609
Synonyms MODY2, LGLK, HXKP, HKIV, HK4, HHF3, glucokinase (hexokinase 4), GLK, GK, FGQTL3
Anti-Glucokinase Antibody (5Q209) is a Mouse antibody targeting Glucokinase. Anti-Glucokinase Antibody (5Q209) can be used in ELISA.
Anti-Glucokinase Antibody
(5Q209)
(5Q209)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 100 μL | $198 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
Add to Cart
Add to Quotation
For research use only—not for human use. No sales to individuals. Use as intended only.
Resource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Glucokinase Antibody (5Q209) is a Mouse antibody targeting Glucokinase. Anti-Glucokinase Antibody (5Q209) can be used in ELISA. |
| Synonyms | MODY2, LGLK, HXKP, HKIV, HK4, HHF3, glucokinase (hexokinase 4), GLK, GK, FGQTL3 |
| Ig Type | Mouse IgG1 |
| Clone | 5Q209 |
| Reactivity | Human |
| Specificity | Human Glucokinase |
| Application | |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Glucokinase (rh Glucokinase; TMPY-04394; NP_000153.1; Leu2-Gln465). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Glucokinase belongs to the bacterial glucokinase family. Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI). It can Catalyzes the initial step in utilization of glucose by the beta-cell and liver at physiological glucose concentration. Glucokinase has a high Km for glucose, and so it is effective only when glucose is abundant. The role of GCK is to provide G6P for the synthesis of glycogen. Pancreatic glucokinase plays an important role in modulating insulin secretion. Hepatic glucokinase helps to facilitate the uptake and conversion of glucose by acting as an insulin-sensitive determinant of hepatic glucose usage. It has a pivotal role as glucose sensor of the pancreatic beta-cells. Glucokinase explains the capacity, hexose specificity, affinities, sigmoidicity, and anomeric preference of pancreatic islet glycolysis, and because stimulation of glucose metabolism is a prerequisite of glucose stimulation of insulin release, glucokinase also explains many characteristics of this beta-cell function. Glucokinase of the beta-cell is induced or activated by glucose in contrast to liver glucokinase, which is regulated by insulin. Tissue-specific regulation corresponds with observations that liver and pancreatic beta-cell glucokinase are structurally distinct. Glucokinase could play a glucose-sensor role in hepatocytes as well, and certain forms of diabetes mellitus might be due to glucokinase deficiencies in pancreatic beta-cells, hepatocytes, or both. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human Glucokinase Protein (TMPY-04394) |
| Antigen Species | Human |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
Calculator
Preview
Related Tags: buy Anti-Glucokinase Antibody (5Q209) | purchase Anti-Glucokinase Antibody (5Q209) | Anti-Glucokinase Antibody (5Q209) cost | order Anti-Glucokinase Antibody (5Q209)
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.