1. Deoxyshikonin (Arnebin 7) may be a new drug candidate for wound healing and treatment of lymphatic diseases. 2. Deoxyshikonin enhances the ability of human dermal lymphatic microvascular endothelial cells (HMVEC-dLy) to undergo time-dependent in vitro cord formation. 3. Deoxyshikonin and dodecyl gallate show significantly synergic antimicrobial activity with penicillin in vivo and in vitro, and can effectively reduce nasopharyngeal and lung colonization caused by different penicillin-resistant pneumococcal serotypes.

Menadione (Vitamin K3) is a synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2, menaquinone, after alkylation in vivo.

Deoxylapachol has anti-wood rot activity, it can inhibit the brown rot fungi Gloeophyllum sepiarium CBS 353.74 and Gloeophyllum trabeum CBS 318.50 and the white rot fungi Merulius tremellosus CBS 280.73 and Phlebia brevispora CBS 509.92. It also can induc

Tanshinone IIA (Tanshinone B) is a diterpene quinone natural product that targets the protein kinase domain of VEGF/VEGFR2. Tanshinone IIA inhibits angiogenesis and exhibits anti-inflammatory, antioxidant, and therapeutic activities against coronary heart disease.

Vitamin K1 (Phylloquinone) a fat-soluble, naturally occurring vitamin with antihemorrhagic and prothrombogenic activity.

Neocryptotanshinone inhibits rabbit platelet aggregation induced by arachidonic acid.

Cryptotanshinone (Cryptotanshinon), a STAT3 inhibitor (IC50: 4.6 μM) in a cell-free assay, strongly inhibits phosphorylation of STAT3 Tyr705, with a little effect on STAT3 Ser727, but no inhibition for STAT1 nor STAT5.

β-Lapachone (ARQ-501) is a specific DNA topoisomerase I inhibitor, and no inhibitory activities against DNA topoisomerase II or ligase.

Menaquinone-4 (Vitamin K2) is a vitamin K compound used as a hemostatic agent, and also as adjunctive therapy for the pain of osteoporosis.

Juglone (Regianin) is a natural naphthoquinone found in the black walnut (J. nigra) and other plants in the Juglandaceae family. Juglone also irreversibly inhibits peptidyl-prolyl cis/trans isomerases of the parvulin family, including human Pin1, yeast Ess1/Ptf1, and E. coli parvulin (Ki = 55.9 nM). Juglone also blocks transcription by RNA polymerases I, II, and III (IC50s = 2-7 μM) and attenuates kidney fibrosis in rats treated with unilateral ureteral obstruction, both through Pin1-independent mechanisms.

Lawsone methyl ether (2-Methoxy-1,4-naphthoquinone) induces apoptosis in A549 cells independently of cell cycle arrest, mediated by JNK and p38 MAPK signaling pathways. These pathways are activated due to oxidative DNA damage from increased ROS generation in MNQ-treated A549 cells.

Lawsone (Hennotannic acid) (2-hydroxy-1,4-naphthoquinone), also known as hennotannic acid, is a red-orange dye present in the leaves of the henna plant (Lawsonia inermis) as well as in the flower of water hyacinth (Eichhornia crassipes).

Lapachol (CI75490) has antimicrobial properties against many pathogens. It has anti-inflammatory, analgesic and antibiotic properties. It is an inhibitor of epithelial tumors in Drosophila melanogaster heterozygote.

α-Lapachone has antineoplastic activity, it shows an approximately trypanocidal activity against Trypanosoma cruzi.

Asperaldin is a potent inhibitor of aldose reductase (RLAR) and can be found in Aspergillus niger CFR-1046.

Danshenxinkun A is a natural product isolated from Salvia miltiorrhiza (Tanshen) exhibiting neuraminidase inhibitory activity with an IC50 of 39.5 mg/L.

Mansonone E is a topoisomerase II inhibitor with cytotoxic and topo inhibitory potencies.

7-Demethylnaphterpin (Naphthgeranine A) is a radical scavenger that can be isolated from Streptomyces prunicolor.

Tanshinol B, a bioactive component isolated from the 50% ethanol extract of Salvia miltiorrhiza roots and rhizomes, is also found in Seaweed prowazekii [1].

Tiancimycin A (TNM A) is an anticancer compound that induces rapid DNA damage, cell cycle arrest, and apoptosis. It can be isolated from the Streptomyces genus, specifically strain CB03234.

Hibarimicin B (Angelmicin B) is a tyrosine kinase inhibitor that selectively inhibits the activity of src tyrosine kinase. It does not affect protein kinase A or C. Additionally, it exhibits moderate antibacterial activity against gram-positive bacteria, with a MIC range of 0.8-12.56 μg/mL.

Herbarin is a natural product for research related to life sciences. The catalog number is TN5793 and the CAS number is 36379-67-6.

Arizonin C3 is a microbial metabolite with activity against Gram-positive bacteria.

Fibrostatin F is a compound found in Streptomyces, acting as a proline hydroxylase (proline hydroxylase).