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5-Hydroxyvanillin

Name: 5-Hydroxyvanillin
Brand: TargetMol
SKU: TN7242
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN7242Cas No. 3934-87-0

Alias 3,4-Dihydroxy-5-methoxybenzaldehyde

5-Hydroxyvanillin (3,4-Dihydroxy-5-methoxybenzaldehyde) can be isolated from indica rice and has an inhibitory effect on Staphylococcus aureus, which can be used for the treatment and prevention of osteoporosis.

5-Hydroxyvanillin

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Purity: 99.08%

Catalog No. TN7242Alias 3,4-Dihydroxy-5-methoxybenzaldehydeCas No. 3934-87-0

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 g	$29	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.08%

Appearance:Solid

Color:Yellow

Resource Download

COA HNMR LCMS

Product Introduction

5-Hydroxyvanillin AI Summary

5-Hydroxyvanillin exhibits potent growth inhibition activity across various human tumor cell lines, as demonstrated in NCI assays. It has a consistent GI50 value of 100000.0 nM in most cell lines tested, indicating a broad spectrum of bioactivity against different cancer cell types. However, there are variations in potency observed in specific cell lines: Leukemia (GI50 46665.94 nM and 57942.87 nM), Melanoma (GI50 27352.69 nM), and Colon (GI50 8072.35 nM), suggesting a differential impact on these cancer types. Overall, 5-Hydroxyvanillin shows significant bioactivity in inhibiting the growth of various human tumor cell lines, positioning it as a potential candidate for further anti-cancer drug development..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	5-Hydroxyvanillin (3,4-Dihydroxy-5-methoxybenzaldehyde) can be isolated from indica rice and has an inhibitory effect on Staphylococcus aureus, which can be used for the treatment and prevention of osteoporosis.
Synonyms	3,4-Dihydroxy-5-methoxybenzaldehyde

Chemical Properties

Molecular Weight	168.15
Formula	C₈H₈O₄
Cas No.	3934-87-0
Smiles	COc1cc(C=O)cc(O)c1O

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (327.09 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.9471 mL	29.7354 mL	59.4707 mL	297.3536 mL
5 mM	1.1894 mL	5.9471 mL	11.8941 mL	59.4707 mL
10 mM	0.5947 mL	2.9735 mL	5.9471 mL	29.7354 mL
20 mM	0.2974 mL	1.4868 mL	2.9735 mL	14.8677 mL
50 mM	0.1189 mL	0.5947 mL	1.1894 mL	5.9471 mL
100 mM	0.0595 mL	0.2974 mL	0.5947 mL	2.9735 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc