Acetyl phosphate lithium potassium (Lithium potassium acetyl phosphate) is a compound involved in taurine and hypotaurine metabolism as well as pyruvate metabolism. Acetyl phosphate lithium potassiu is generated from sulfoacetaldehyde, converted to acetyl-CoA and acetate via phosphate acetyltransferase and acetate kinase respectively. Acetyl phosphate lithium potassiu is also an intermediate in pyruvate metabolism.

Potassium 1H-indol-3-yl sulfate (Potassium 3-indoxyl sulfate) is an agonist for the human Aryl Hydrocarbon Receptor (AhR), a key regulator of immune-inflammatory conditions. A metabolite of tryptophan derived from dietary protein, it is produced by intestinal bacteria and metabolized in the liver. In chronic kidney disease patients with impaired renal function, it accumulates in serum as a uremic toxin, inducing oxidative stress and accelerating disease progression. At 250 μM, it activates NF-Κb, promoting TGF-β1 and Smad3 expression in rat proximal tubular cells, which is associated with profibrotic activity.

Potassium 1-carboxyvinyl hydrogenphosphate (PEP-K) is involved in glycolysis and gluconeogeneis. In glycolysis, PEP is metabolized by Pyruvate Kinase to yield pyruvate. In plants, PEP is involved in the formation of aromatic amino acids as well as in the carbon fixation pathway.

Phosphonoacetate, also known as fosfonet or phosphonacetic acid, belongs to the class of organic compounds known as organic phosphonic acids.Within the cell, phosphonoacetate is primarily located in the cytoplasm. Phosphonoacetate can be biosynthesized fr

Ureidopropionic acid (3-Ureidopropionic acid) is an intermediate in uracil metabolism, produced from dihydrouracil by the enzyme dihydropyrimidase and further decomposed to beta-alanine by beta-ureidopropionase. It is a urea derivative of beta-alanine. High levels of Ureidopropionic acid are found in individuals with beta-ureidopropionase (UP) deficiency. Enzyme deficiencies in pyrimidine metabolism are associated with severe toxicity to the antineoplastic agent 5-fluorouracil.

(E/Z)-Ginkgolic Acid C17:2 (Ginkgolic Acid C17:2) is a natural product extracted from Ginkgo biloba that targets human dihydroorotate dehydrogenase (DHODH).

(2-Aminoethyl)phosphonic acid (2-Aminoethylphosphonic acid) is primarily detected in urine. (2-Aminoethyl)phosphonic acid participates in many enzymatic reactions and is also the parent compound of other transformation products, including but not limited to ceramide 2-(methylamino)ethylphosphonate, N-(2-phosphineethyl)cholamide and CMP-2-aminoethylphosphonate.

Isethionic acid sodium salt (Sodium isethionate) is an organosulfur compound containing a short chain alkane sulfonate linked to a hydroxyl group. Mammals are able to endogenously synthesize Isethionic acid sodium salt via taurine through a possible enzymatic deamination process. Isethionic acid sodium salt can be found in both human plasma and urine. Higher plasma levels of Isethionic acid sodium salt have been shown to be protective against type 2 diabetes.

Dephospho-CoA (dpCoA) is an endogenous compound extracted from Escherichia coli and Lactobacillus plantarum, and is an intermediate in coenzyme A biosynthesis.