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Chalcones

TargetMol offers 19,000+ natural products, including Chalcones-related compounds, with clear sources, diverse structures, and available Latin scientific names.

Helichrysetin
TN172762014-87-3
Helichrysetin has mild anti-HIV-1 PR activity. Helichrysetin has great potentials for development as an anticancer agent, it has cytotoxic effect on four selected cancer cell lines, A549, MCF-7, Ca Ski, and HT-29.
  • $97
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Asebogenin
TN3460520-42-3
Asebogenin is a compound fractionated from Salvia miltiorrhiza with antifungal activity, inhibition of GPVI-induced platelet reactions, and inhibition of NET formation induced by pro-inflammatory stimuli.
  • $653
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Licochalcone D
T4518144506-15-0
Licochalcone D may be a potential drug for human melanoma treatment by inhibiting proliferation, inducing apoptosis via the mitochondrial pathway and blocking cell migration and invasion. Licochalcone D has cardioprotective potential against myocardial is
  • $97
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Nothofagin
TN199611023-94-2In house
Nothofagin has antioxidant, and antithrombotic activities, it possesses anti-inflammatory activity by inhibiting hyperpermeability, expression of CAMs, and adhesion and migration of leukocytes, thereby endorsing its usefulness as a therapy for vascular inflammatory diseases.
  • $293
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Echinatin
T392634221-41-5
Echinatin (Retrochalcone) is extracted from licorice and is a natural chalcone. Echinatin has a wide range of biological activities including hepatoprotective, anti-inflammatory, anti-bacterial infections, and attenuates lung damage.
  • $31
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Loureirin C
TN1054116384-24-8
Loureirin C can inhibit the activities of thrombin in vitro effectively.
  • $64
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Licochalcone B
T4S035058749-23-8
1. Licochalcone B (LCB) inhibits the proliferation of human malignant bladder cancer cell lines (T24 and EJ) in vitro and antitumor activity in vivo in MB49 (murine bladder cancer cell line) tumor model. 2. LCB and Licochalcone D(LCD) significantly reduce
  • $48
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Homobutein
TN422034000-39-0
Homobutein (3-O-Methylbutein) is a dual inhibitor of HDACs and NF-κB with IC50s of 190 and 38 μM. Homobutein is an iron chelator with anticancer, anti-inflammatory, antiparasite, and antioxidation activities.
  • $98
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Okanin
TN2008484-76-4
Okanin shows significant activities on both linoleic acid peroxidation inhibition and DPPH radical scavenging effect.
  • $80
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(E)-Naringenin chalcone
T2S217373692-50-9
Naringenin chalcone (Isosalipurpol) has antiallergic activity Naringenin chalcone suppresses asthmatic symptoms by inhibiting Th2 cytokine production from CD4 T cells. Naringenin chalcone is a potent tomato flavonoid that improves adipocyte metabolic functions and exerts insulin-sensitizing effects by activating an adiponectin-related pathway. Naringenin chalcone exhibits anti-inflammatory properties by inhibiting the production of proinflammatory cytokines in the interaction between adipocytes and macrophages, may be useful for ameliorating the inflammatory changes in obese adipose tissue.
  • $39
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Hydroxysafflor yellow A
T367478281-02-4
Hydroxysafflor yellow A (Safflomin A) inhibits adipogenesis by increasing HSL promoter activities, effectively protects the liver from long-term alcohol injury by enhancing antioxidant capacity and inhibiting the expression of TGF-β, prevents steroid-induced avascular necrosis of the femoral head by inhibiting primary bone marrow-derived mesenchymal stromal cells, and exhibits anti-tumor effects.
  • $37
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2'-O-Methylisoliquiritigenin
TN121751828-10-5
2'-O-Methylisoliquiritigenin, a compound synthesized by enzymes specifically induced in NR.2'-O-Methylisoliquiritigenin, isolated from the Arachis species, up-regulates 5-HT, NE, DA and GABA pathways, but does not put a very significant effect on ne NE pathway.
  • $123
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Pinocembrin chalcone
TN20784197-97-1
Pinocembrin chalcone is an inhibitor of tyrosinase with antimutagenic effects. Pinocembrin chalcone can be used in studies about the prevention of gastric ulcers.
  • $68
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Trilobatin
T2S07314192-90-9
Trilobatin (P-Phlorizin) has anti-oxidant effect, can increase superoxide dismutase (SOD) activity.Trilobatin has anti-inflammatory effect, it potentially inhibits the lipopolysaccharide (LPS)-induced inflammatory response by suppressing the NF-κB signaling pathway.Trilobatin shows a strong inhibitory activity against α-glucosidase and a moderate inhibitory activity against α-amylase for management of postprandial hyperglycemia with less side effect.
  • $50
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Linderone
TN18721782-79-2
Linderone, a compound isolated from Lindera erythrocarpa, has antioxidant and anti-inflammatory activity and can be used to study neuroinflammation.
  • $355
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4'-Methoxychalcone
T7443959-23-9
4'-Methoxychalcone with a variety of pharmacological activities, such as anti-tumor and anti-inflammatory activities.
  • $29
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Sappanchalcone
TN218094344-54-4
Sappanchalcone shows xanthine oxidase inhibitory activity, is a xanthine oxidase inhibitor.
  • $247
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4,4′-Dihydroxy-2,6-dimethoxydihydrochalcone
TN1878151752-08-8
4,4′-Dihydroxy-2,6-dimethoxydihydrochalcone is isolated from the stem wood of Dracaena loureiri.
  • $88
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3,4-Dimethoxychalcone
TN28825416-71-7
3,4-Dimethoxychalcone is a natural product found in the flowers of Arrabidaea brachypoda.
  • $34
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Phlorizin dihydrate
T2S20037061-54-3
1. Phlorizin dihydrate (Phloridzin dihydrate) can significantly inhibit oxidative DNA damage.
  • $29
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Licochalcone E
TN1055864232-34-8
Licochalcone E is a potential LXRβ agonist.
  • $98
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Homoeriodictyol chalcone
TN918052218-19-6
Homoeriodictyol chalcone(2',4,4',6'-tetrahydroxy-3-methoxychalcone) is a natural chalcone glucoside used in biochemical experiments and organic synthesis.
  • $195
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4'-Hydroxy-2,4-dimethoxychalcone
TN3033151135-64-7
4'-Hydroxy-2,4-dimethoxychalcone, a naturally occurring chalcone derivative from the herbal resin of the red geranium [Dragon's Blood], exhibits a wide range of biological activities including anti-malarial, anti-bacterial, anti-fungal, and anti-protozoa properties.
  • $77
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3-Hydroxyphloridzin
TN867630779-02-3
3-Hydroxyphloridzin is a natural dihydrochalcone glycoside with inhibitory activity against xanthine dehydrogenase (IC₅₀ = 52.1 µM).
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7-10 days
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