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Xanthones

TargetMol offers 19,000+ natural products, including Xanthones-related compounds, with clear sources, diverse structures, and available Latin scientific names.

gamma-Mangostin
T4S163731271-07-5
1. gamma-Mangostin (Normangostin) as a preventive agent of the metabolic syndrome. 2. Gamma-Mangostin has free radical scavenging activity, and antiproliferative and apoptotic activity in HepG2 cells. 3. Gamma-Mangostin could serve as a micronutrient for colon cancer prevention and is a potential lead compound for the development of anti-colon cancer agents. 4. Gamma-Mangostin may acts as an antihypertensive agent , by causing vasorelaxation which is mediated via the NO-cGMP pathway.
  • $44
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1-Isomangostin
TN254619275-44-6
1-Isomangostin has cytotoxic and anticomplementary activities.
  • $117
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Beta-mangostin
TN101920931-37-7
Beta-mangostin (β-Mangostin) is a xanthone compound with antibacterial and antimalarial activities. Beta-mangostin present in Cratoxylum arborescens and exhibits antimycobacterial activity against Mycobacterium tuberculosis with an MIC of 6.25 μg/mL. Beta-mangostin possesses in vitro antimalarial activity against Plasmodium falciparum, with an IC50 of 3.00 μg/mL. Beta-mangostin has potent anticancer activity against various cancers (such as hepatocellular carcinoma, leukaemic).
  • $47
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3-Isomangostin
T2S163519275-46-8
3-Isomangostin is a potent human aldose reductase inhibitor with an IC50 of 3.48 uM; it is also an acetylcholinesterase selective inhibitor. 3-Isomangostin has free radical scavenging activity; it shows antiplasmodial activity with IC50 values in the rang
  • $35
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Garcinone C
TN167376996-27-5
Garcinone C is a xanthone derivative extracted from Garcinia oblongifolia Champ with anti-inflammatory, astringency, and granulation-promoting activities. Garcinone C is an AChE inhibitor and has potential cytotoxic effects on certain cancers.
  • $38
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Norathyriol
TN19903542-72-1
Norathyriol is a potent PTP1B inhibitor with good cell permeability and oral availability.
  • $152
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Gentisin
TN1683437-50-3
Gentisin is a novel inhibitor of vascular smooth muscle cells (VSMC) proliferation with an IC50 value of 7.84 μM. Gentisin has mutagenic activity.
  • $106
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8-Deoxygartanin
TN134133390-41-9
8-Deoxygartanin is a butyrylcholinesterase (BChE) selective inhibitor, it exhibits significant inhibition of self-induced α2-amyloid (Aα2) aggregation, it has multifunctional activities against Alzheimer's disease (AD) and could be promising compounds for the therapy of AD.
  • $58
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Maclurin
T20578519-34-6
Maclurin (NSC-83240) is a phenolic component of mulberry twigs, exerts anti-metastatic effects. Maclurin effectively protects against OH-induced damages to DNA and MSCs and can be used in studies about the prevention of many diseases or MSCs transplantation.
  • $30
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1,3,5,8-Tetrahydroxyxanthone
TN10842980-32-7
1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin) is a natural xanthone extracted from Gentianella acuta, exhibiting antispasmodic and anti-inflammatory activities. Dimethylbellidifolin shows mutagenicity in Salmonella typhimurium TA100, TA98, TA97, and TA2637 by the preincubation method and significantly inhibits the growth of Staphylococcus aureus at a dose of 200 µg/disk.
  • $89
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Euxanthone
T4001529-61-3
Euxanthone (1,7-Dihydroxyxanthone), an xanthone derivative extracted from the roots of Polygala tenuifolia Willd, has antitumour, neuroprotective and vasorelaxant activities, and attenuates Aβ1-42-induced oxidative stress and apoptosis by inducing autophagy.SB-674042 is used for the treatment of depression.SB-674042 is used for the treatment of depression.SB-674043 is used for the treatment of depression.SB-674044 is used for the treatment of depression.SB-674045 is used for the treatment of depression. 2A (BU-1) cell differentiation.
  • $195
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Mangiferin
T30124773-96-0
Mangiferin (Hedysarid) is used for antidiabetes. Extracted from Mangifera indica L.
  • $38
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Gentisein
T19931529-49-7
Gentisein (NSC-329491), a primary metabolite of Mangiferin, exhibits significant inhibition of serotonin uptake, demonstrating potency with an IC50 value of 4.7 µM[1][2].
  • $40
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Gartanin
TN167733390-42-0
Gartanin is an androgen receptor degradation enhancer, it is also a potential neuroprotective agent against glutamate-induced oxidative injury partially through increasing Nrf-2-independed HO-1 and AMPK/SIRT1/PGC-1α±signaling pathways.
  • $98
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Fuscaxanthone C
TN165215404-76-9
Fuscaxanthone C is a natural product from Garcinia mangostana.
  • $100
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Iriflophenone
TN176852591-10-3
Iriflophenone stimulates cells proliferation in  MCF-7 and T-47D human breast cancer.
  • $74
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Cratoxylone
TN1531149155-01-1
Cratoxylone is derived from the bark of the Cochin tree and has anti-plasmodial activity and potential anti-tumor and antioxidant activity.
  • $98
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Cowaxanthone B
TN1530212842-64-3
Cowaxanthone B is a new tetraoxoanthrone isolated from the fruit of Garcinia cambogia.Cowaxanthone B has potential antibacterial activity.
  • $175
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Formoxanthone A
TN4071869880-32-0
Formoxanthone A may have antibacterial and cytotoxic activities.
  • $879
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1,3,7-Trihydroxy-2-prenylxanthone
TN248920245-39-0
1,3,7-Trihydroxy-2-prenylxanthone (Isombarraxanthone) shows weak antibacterial activity against the bacterium.
  • $2,608
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6-Deoxyjacareubin
TN316116265-56-8
6-Deoxyjacareubin exhibits potent antioxidant and antifungal activities. 6-Deoxyjacareubin inhibits platelet activating factor (PAF) receptor with an IC50 of 29.0 microM and can be used in studies about natural PAF receptor antagonists.
  • $829
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Garcinone E
TN4113112649-21-5
Garcinone E is active constituents in the anticomplement assay used. Garcinone E exhibits potent activity in vitro against Plasmodium falciparum chloroquine-resistant strain W2, with IC50 values below 3 µM. It has potent cytotoxic effect on all hepatocellular carcinomas cell lines as well as on the other gastric and lung cancer cell lines included in the screen, may be potentially useful for the treatment of certain types of cancer.
  • $2,798
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Mangostanol
TN4492184587-72-2
Mangostanol is an acetylcholinesterase (AChE) selective inhibitor.Mangostanol has anti-cancer activity, it shows significant activities against the CEM-SS cell line, with IC50 values of 9.6 microg ml.
  • $698
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1,6,7-Trihydroxyxanthone
TN250725577-04-2
1,6,7-Trihydroxyxanthone has anti-cancer activity ,at least in part, through the activation of miR-218 and suppression of Bmi-1 expression; can suppress cell growth and induce apoptosis in liver cancer cells.
  • $550
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