b cells

Alloxan Monohydrate is a glucose analog used to induce diabetes by destroying beta-cells.

Hygromycin B (Hygrovetine) is an aminoglycoside antibiotic that inhibits protein synthesis by interfering with translocation and causing mistranslation of the 70S ribosome. Hygromycin B can be used to screen prokaryotic or eukaryotic cells transfected with hph or hyg resistance genes.

Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist and IL receptor modulator with anti-inflammatory and immunosuppressive properties that induces autophagy and inhibits LPS-induced inflammatory responses in macrophages.

Streptozocin (NSC-85998) is an antibiotic that induces DNA methylation. Streptozocin is toxic to insulin-producing pancreatic islet B-cells and is commonly used in the construction of animal models of type 1 diabetes. The product is unstable in solution and is recommended to be dispensed now.

G6PI 325-339 (human) effectively induces arthritis in B10.Q mice, primes Th1 and Th17 cells to cross-react with the murine G6PI protein, and triggers an arthritis model via a T and B cell-dependent pathway, although it operates without antibody effector mechanisms [1].