stat — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T35407	Ζ-Stat		PKC
	ζ-Stat (NSC37044), a specific and atypical inhibitor of PKC-ζ with an IC50 of 5 μM, demonstrates the ability to inhibit proliferation and induce apoptosis in melanoma cell lines, exhibiting antitumor activity in vitro[1]...		PKC
T40395	ζ-Stat trisodium	NSC37044 trisodium,ζ-Stat trisodium
	ζ-Stat trisodium (NSC37044 trisodium) is a potent and selective inhibitor of protein kinase C-ζ (PKC-ζ), exhibiting an IC50 of 5 μM. It effectively suppresses the proliferation of melanoma cell lines and promotes apoptos...
T78607	JAK-STAT-IN-1		JAK , STAT
	JAK-STAT-IN-1 is a specific JAK-STAT inhibitor indicated for the study of autoimmune diseases.		JAK , STAT
T13009	STAT3-IN-1		Apoptosis , STAT
	STAT3-IN-1 selective and orally active inhibitor of STAT3(in HT29 and MDA-MB 231 cells, with IC50 values of 1.82 μM and 2.14 μM , respectively), induces tumor apoptosis.		Apoptosis , STAT
T4216	STAT5-IN-1	STAT5 Inhibitor	STAT
	STAT5-IN-1 (STAT5 Inhibitor) is a cell-permeable inhibitor which suppresses Stat5 via binding to the SH2 domain.		STAT
TN2346	Mogrol		ERK , AMPK , STAT
	Mogrol, a biometabolite of mogrosides, functions by inhibiting the ERK1/2 and STAT3 pathways, diminishing CREB activation, and activating AMPK signaling.		ERK , AMPK , STAT
T16940	STAT5-IN-2		Apoptosis , STAT
	STAT5-IN-2 is an inhibitor of STAT5 with antileukemic effects (EC50s: 9 μM and 5 μM in K562 and KU812 cells, respectively).		Apoptosis , STAT
T6669	SH-4-54		STAT
	SH-4-54 is a most potent, small molecule, nonphosphorylated STAT3 inhibitor.		STAT
T3708	BP-1-102		STAT
	BP-1-102 is an orally active, effective and specific STAT3 inhibitor. BP-1-102 binds Stat3 (Kd: 504 nM), then blocks Stat3-phosphotyrosine (pTyr) peptide interactions and Stat3 activation (4-6.8 μM), and selectively inhi...		STAT
T4476	AS1517499		STAT
	AS1517499 is a potent STAT6 inhibitor with IC50 of 21 nM		STAT
T2867	Diosgenin	Nitogenin	STAT
	Diosgenin (Nitogenin) is a spirostan found in DIOSCOREA and other plants. It has favorable effects in the improvement of diabetes and regulation of lipid metabolism.		STAT
T4672	Brevilin A		Apoptosis , Anti-infection , JAK , STAT , Autophagy
	Brevilin A is a sesquiterpene lactone isolated from Centipeda minima, inhibits janus kinase activity and blocks STAT3 signaling in cancer cells with anti-tumor activity. Brevilin A is a selective inhibitor of JAK-STAT si...		Apoptosis , Anti-infection , JAK , STAT , Autophagy
T15582	InS3-54A18		STAT
	inS3-54A18 is an effective inhibitor of STAT3. inS3-54A18 has anticancer effects.		STAT
TQ0052	SH5-07		STAT
	SH5-07 is a hydroxamic acid-based Stat3 inhibitor (IC50: 3.9 μM).		STAT
T2505	S3I-201	S3I 201,S3I201	STAT
	S3I-201 (S3I-201) is a selective Stat3 inhibitor (IC50: 86±33 μM) and low effect towards STAT1/5.		STAT
T9339	Stafia-1		STAT
	Stafia-1 is a potent STAT5a inhibitor ( IC50=22.2 μM). Stafia-1 displays high selectivity over STAT5b and other STAT family members.		STAT
T6838	FLLL32		Apoptosis , JAK , STAT
	FLLL32 is an effective JAK2/STAT3 inhibitor (IC50 of <5 μM).		Apoptosis , JAK , STAT
T2168	2-(1,8-naphthyridin-2-yl)phenol		STAT
	2-NP is a STAT1 enhancer.		STAT
T6S0071	Fraxinellone		HIF/HIF Prolyl-Hydroxylase , STAT , PD-1/PD-L1
	1. Fraxinellone significantly reduced weight loss and diarrhea in mice and alleviated the macroscopic and microscopic signs of the disease. 2. Fraxinellone exhibited a variety of insecticidal activities including feeding...		HIF/HIF Prolyl-Hydroxylase , STAT , PD-1/PD-L1
T6537	HO-3867	HO3867	Apoptosis , STAT
	HO-3867, an analog of curcumin, is a sspecific STAT3 inhibitor.		Apoptosis , STAT