5-HT Receptor

5-hydroxytryptamine receptors or 5-HT receptors, or serotonin receptors, are a group of G protein-coupled receptor and ligand-gated ion channels found in the central and peripheral nervous systems. They mediate both excitatory and inhibitory neurotransmission.

Cat. No.	Product name	CAS No.	Purity
T22296	Cisapride hydrate	260779-88-2	98%
T22296	Cisapride acts directly as a selective agonist of serotonin 5-HT4 receptor with IC50 value of 0.483 μM. And It also acts indirectly as a parasympathomimetic.
T10371	Arotinolol	68377-92-4	98%
T10371	Arotinolol is a nonselective α/β-adrenergic receptor blocker and a vasodilating β-blocker. Arotinolol also shows potency for inhibiting the binding of the radiol...
T10075L	2-Methyl-5-HT maleate	78263-91-9	98%
T10075L	2-Methyl-5-HT maleate (2-Methyl-5-hydroxytryptamine maleate) is a potent and selective 5-HT3 receptor agonist, which is shown to display anti-depressive-like eff...
T11293	(±)-Fabesetron hydrochloride	129299-81-6	98%
T11293	FK1052 hydrochloride is a potent 5-HT3 and 5-HT4 receptor dual antagonist.
T12489L	Pimethixene maleate	13187-06-9	98%
T12489L	Pimethixene maleate is a highly potent5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, histamine H1, dopamine D2 and D4.4 as well as muscarinic M1 and M2 receptors antagonist(wit...
T10495	Befiradol hydrochloride (208110-64-9 free base)	2436760-81-3	98%
T10495	Befiradol (NLX-112) hydrochloride is a selective agonist of the 5-HT1A receptor.
TN3235	7-Hydroxycadalene	2102-75-2	98%
TN3235	7-Hydroxycadalene shows cytotoxicity activity against HCT-15 cell line with IC50 18.89 ± 1.2 uM.
T11302	Flumexadol	30914-89-7	98%
T11302	Flumexadol is a selective and affinity 5-HT2C receptor agonist with a Ki of 25 nM for the (+)-enantiomer of Flumexadol, and is 40-fold selective over the 5-HT2A ...
TN4092	Galanolactone	115753-79-2	98%
TN4092	Galanolactone has anti-5-HT effect, a diterpenoid isolated from ginger, is related to antagonism of 5-HT3 receptors, it has inhibit nitric oxide production with ...
T12632L	(S)-Mirtazapine	61337-87-9	98%
T12632L	(S)-Mirtazapine is an S(+)-enantiomer of Mirtazapine. (S)-Mirtazapine is a stereoselective 5-HT2 receptor antagonist.
T1769	Pardoprunox	269718-84-5	98%
T1769	Pardoprunox is a partial dopamine D2 agonist and noradrenergic agonist with serotonin 5-HT1A agonist properties. Pardoprunox has been used in trials studying the...
T12215	Nexopamil racemate	116759-35-4	98%
T12215	Nexopamil racemate is the racemate of Nexopamil. Nexopamil is a combined Ca2+/5-HT2 antagonist on platelet aggregation in vitro and on thrombus formation in vivo...
T12842	SB-269970	201038-74-6	98%
T12842	SB-269970 is a antagonist of 5-HT7 receptor(pKi of 8.3).
T10075L2	2-Methyl-5-HT hydrochloride	845861-49-6	98%
T10075L2	2-Methyl-5-HT hydrochloride (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist with anti-depressive-like effects.
T4375	Methiothepin maleate	19728-88-2	98%
T4375	Methiothepin is a 5-HT1, 5-HT6, 5-HT7 serotonin receptor antagonist, which blocks serotonin autoreceptors.
T12262	NPS ALX Compound 4a	299433-10-6	98%
T12262	NPS ALX Compound 4a is a potent and selective antagonist of 5-HT6 receptor (IC50 of 7.2 nM)
TQ0315	Tandospirone	87760-53-0	98%
TQ0315	Tandospirone (SM-3997) is a selective partial agonist of 5-HT1A receptor (Ki: 27 nM) that displays selectivity over SR-2, SR-1C, α1, α2, D1 and D2 receptors (Kis...
T10498	5-HT2A antagonist 1	204643-75-4	98%
T10498	5-HT2A antagonist 1 is a 5-HT2A antagonist extracted from patent US5728835A and JP 1007727. It may be useful in the treatment of gastrointestinal disorders circu...
T10267	Agomelatine (L(+)-Tartaric acid)	824393-18-2	98%
T10267	Agomelatine (S-20098) L(+)-Tartaric acid is a specific agonist of MT1 and MT2 receptors (Kis: 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and ...
T12631	(R)-Mirtazapine D3	T12631	98%
T12631	(R)-Mirtazapine D3 is a deuterium labeled (R)-Mirtazapine.(R)-Mirtazapine is a antagonist of 5-HT3 receptor.