Home Tools
Log in
Cart

5-HT Receptor

5-hydroxytryptamine receptors or 5-HT receptors, or serotonin receptors, are a group of G protein-coupled receptor and ligand-gated ion channels found in the central and peripheral nervous systems. They mediate both excitatory and inhibitory neurotransmission.
Cat. No. Product name CAS No. Purity Chemical Structure
T22296 Cisapride hydrate 260779-88-2 98%
Cisapride acts directly as a selective agonist of serotonin 5-HT4 receptor with IC50 value of 0.483 μM. And It also acts indirectly as a parasympathomimetic.
T10371 Arotinolol 68377-92-4 98%
Arotinolol is a nonselective α/β-adrenergic receptor blocker and a vasodilating β-blocker. Arotinolol also shows potency for inhibiting the binding of the radiol...
T10075L 2-Methyl-5-HT maleate 78263-91-9 98%
2-Methyl-5-HT maleate (2-Methyl-5-hydroxytryptamine maleate) is a potent and selective 5-HT3 receptor agonist, which is shown to display anti-depressive-like eff...
T11293 (±)-Fabesetron hydrochloride 129299-81-6 98%
FK1052 hydrochloride is a potent 5-HT3 and 5-HT4 receptor dual antagonist.
T12489L Pimethixene maleate 13187-06-9 98%
Pimethixene maleate is a highly potent5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, histamine H1, dopamine D2 and D4.4 as well as muscarinic M1 and M2 receptors antagonist(wit...
T10495 Befiradol hydrochloride (208110-64-9 free base) 2436760-81-3 98%
Befiradol (NLX-112) hydrochloride is a selective agonist of the 5-HT1A receptor.
TN3235 7-Hydroxycadalene 2102-75-2 98%
7-Hydroxycadalene shows cytotoxicity activity against HCT-15 cell line with IC50 18.89 ± 1.2 uM.
T11302 Flumexadol 30914-89-7 98%
Flumexadol is a selective and affinity 5-HT2C receptor agonist with a Ki of 25 nM for the (+)-enantiomer of Flumexadol, and is 40-fold selective over the 5-HT2A ...
TN4092 Galanolactone 115753-79-2 98%
Galanolactone has anti-5-HT effect, a diterpenoid isolated from ginger, is related to antagonism of 5-HT3 receptors, it has inhibit nitric oxide production with ...
T12632L (S)-Mirtazapine 61337-87-9 98%
(S)-Mirtazapine is an S(+)-enantiomer of Mirtazapine. (S)-Mirtazapine is a stereoselective 5-HT2 receptor antagonist.
T1769 Pardoprunox 269718-84-5 98%
Pardoprunox is a partial dopamine D2 agonist and noradrenergic agonist with serotonin 5-HT1A agonist properties. Pardoprunox has been used in trials studying the...
T12215 Nexopamil racemate 116759-35-4 98%
Nexopamil racemate is the racemate of Nexopamil. Nexopamil is a combined Ca2+/5-HT2 antagonist on platelet aggregation in vitro and on thrombus formation in vivo...
T12842 SB-269970 201038-74-6 98%
SB-269970 is a antagonist of 5-HT7 receptor(pKi of 8.3).
T10075L2 2-Methyl-5-HT hydrochloride 845861-49-6 98%
2-Methyl-5-HT hydrochloride (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist with anti-depressive-like effects.
T4375 Methiothepin maleate 19728-88-2 98%
Methiothepin is a 5-HT1, 5-HT6, 5-HT7 serotonin receptor antagonist, which blocks serotonin autoreceptors.
T12262 NPS ALX Compound 4a 299433-10-6 98%
NPS ALX Compound 4a is a potent and selective antagonist of 5-HT6 receptor (IC50 of 7.2 nM)
TQ0315 Tandospirone 87760-53-0 98%
Tandospirone (SM-3997) is a selective partial agonist of 5-HT1A receptor (Ki: 27 nM) that displays selectivity over SR-2, SR-1C, α1, α2, D1 and D2 receptors (Kis...
T10498 5-HT2A antagonist 1 204643-75-4 98%
5-HT2A antagonist 1 is a 5-HT2A antagonist extracted from patent US5728835A and JP 1007727. It may be useful in the treatment of gastrointestinal disorders circu...
T10267 Agomelatine (L(+)-Tartaric acid) 824393-18-2 98%
Agomelatine (S-20098) L(+)-Tartaric acid is a specific agonist of MT1 and MT2 receptors (Kis: 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and ...
T12631 (R)-Mirtazapine D3 T12631 98%
(R)-Mirtazapine D3 is a deuterium labeled (R)-Mirtazapine.(R)-Mirtazapine is a antagonist of 5-HT3 receptor.
Cisapride hydrate
T22296
Cisapride acts directly as a selective agonist of serotonin 5-HT4 receptor with IC50 value of 0.483 μM. And It also acts indirectly as a parasympathomimetic.
Arotinolol
T10371
Arotinolol is a nonselective α/β-adrenergic receptor blocker and a vasodilating β-blocker. Arotinolol also shows potency for inhibiting the binding of the radiol...
2-Methyl-5-HT maleate
T10075L
2-Methyl-5-HT maleate (2-Methyl-5-hydroxytryptamine maleate) is a potent and selective 5-HT3 receptor agonist, which is shown to display anti-depressive-like eff...
(±)-Fabesetron hydrochloride
T11293
FK1052 hydrochloride is a potent 5-HT3 and 5-HT4 receptor dual antagonist.
Pimethixene maleate
T12489L
Pimethixene maleate is a highly potent5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, histamine H1, dopamine D2 and D4.4 as well as muscarinic M1 and M2 receptors antagonist(wit...
Befiradol hydrochloride (208110-64-9 free base)
T10495
Befiradol (NLX-112) hydrochloride is a selective agonist of the 5-HT1A receptor.
7-Hydroxycadalene
TN3235
7-Hydroxycadalene shows cytotoxicity activity against HCT-15 cell line with IC50 18.89 ± 1.2 uM.
Flumexadol
T11302
Flumexadol is a selective and affinity 5-HT2C receptor agonist with a Ki of 25 nM for the (+)-enantiomer of Flumexadol, and is 40-fold selective over the 5-HT2A ...
Galanolactone
TN4092
Galanolactone has anti-5-HT effect, a diterpenoid isolated from ginger, is related to antagonism of 5-HT3 receptors, it has inhibit nitric oxide production with ...
(S)-Mirtazapine
T12632L
(S)-Mirtazapine is an S(+)-enantiomer of Mirtazapine. (S)-Mirtazapine is a stereoselective 5-HT2 receptor antagonist.
Pardoprunox
T1769
Pardoprunox is a partial dopamine D2 agonist and noradrenergic agonist with serotonin 5-HT1A agonist properties. Pardoprunox has been used in trials studying the...
Nexopamil racemate
T12215
Nexopamil racemate is the racemate of Nexopamil. Nexopamil is a combined Ca2+/5-HT2 antagonist on platelet aggregation in vitro and on thrombus formation in vivo...
SB-269970
T12842
SB-269970 is a antagonist of 5-HT7 receptor(pKi of 8.3).
2-Methyl-5-HT hydrochloride
T10075L2
2-Methyl-5-HT hydrochloride (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist with anti-depressive-like effects.
Methiothepin maleate
T4375
Methiothepin is a 5-HT1, 5-HT6, 5-HT7 serotonin receptor antagonist, which blocks serotonin autoreceptors.
NPS ALX Compound 4a
T12262
NPS ALX Compound 4a is a potent and selective antagonist of 5-HT6 receptor (IC50 of 7.2 nM)
Tandospirone
TQ0315
Tandospirone (SM-3997) is a selective partial agonist of 5-HT1A receptor (Ki: 27 nM) that displays selectivity over SR-2, SR-1C, α1, α2, D1 and D2 receptors (Kis...
5-HT2A antagonist 1
T10498
5-HT2A antagonist 1 is a 5-HT2A antagonist extracted from patent US5728835A and JP 1007727. It may be useful in the treatment of gastrointestinal disorders circu...
Agomelatine (L(+)-Tartaric acid)
T10267
Agomelatine (S-20098) L(+)-Tartaric acid is a specific agonist of MT1 and MT2 receptors (Kis: 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and ...
(R)-Mirtazapine D3
T12631
(R)-Mirtazapine D3 is a deuterium labeled (R)-Mirtazapine.(R)-Mirtazapine is a antagonist of 5-HT3 receptor.
1 2 3 4 5 ... 23