T0039 |
Dapoxetine
|
119356-77-3
|
99.76%
|
|
Dapoxetine is a selective serotonin reuptake inhibitor, for the treatment of premature ejaculation.
|
T3086 |
Mesoridazine Besylate
|
32672-69-8
|
99.27%
|
|
Mesoridazine (Serentil) is a piperidine neuroleptic drug belonging to the class of drugs called phenothiazines, used in the treatment of schizophrenia. It is a m...
|
T62269 |
F 14679
|
208109-38-0
|
99.09%
|
|
F 14679 is a potent 5-HT1A agonist (pKi=10.23) with a maximum Ca2t response similar to 5-HT.
|
T28414 |
Piclozotan
|
182415-09-4
|
99%
|
|
Piclozotan (anhydrous), a 5-HT1A receptor agonist, demonstrated significant neuroprotective activity in a transient middle cerebral artery occlusion (t-MCAO) mod...
|
T4348 |
Syk Inhibitor II
|
726695-51-8
|
97.63%
|
|
Syk inhibitor II, a cell-permeable, ATP-competitive, pyrimidine-carboxamide compound, selectively and reversibly inhibits Syk (IC50 = 41 nM).
|
T8702 |
SKF-83566
|
99295-33-7
|
95.00%
|
|
SKF-83566 is a blood-brain permeable and orally active antagonist of D1-like dopamine receptor and a weaker competitive 5-HT2 receptor antagonist with Ki of 11 n...
|
T1769 |
Pardoprunox
|
269718-84-5
|
|
|
Pardoprunox is a partial dopamine D2 agonist and noradrenergic agonist with serotonin 5-HT1A agonist properties. Pardoprunox has been used in trials studying the...
|
TN1415 |
Auraptenol
|
1221-43-8
|
98%
|
|
Auraptenol possesses robust antidepressant-like efficacy in mice.
|
T15100 |
Desmethyl cariprazine
|
839712-15-1
|
98%
|
|
Desmethyl cariprazine is a Cariprazine active metabolite. Cariprazine, an antipsychotic drug candidate, shows a high affinity for the D3 (Ki: 0.085 nM) and D2 (K...
|
T17095 |
TIK-301
|
118702-11-7
|
98%
|
|
TIK-301 is a chlorinated melatonin derivative and a potent, high-affinity, and orally active melatonin MT1 and MT2 receptors agonist (Kis: 0.081 nM and 0.042 nM,...
|
T11949 |
Masupirdine mesylate
|
1791396-46-7
|
98%
|
|
Masupirdine mesylate (SUVN-502 mesylate) shows high selectivity over 5-HT2A receptor and other 100 target sites, and has potential for treatment of Alzheimer's d...
|
T19381 |
Isobutyryl-L-carnitine
|
25518-49-4
|
98%
|
|
Isobutyryl-L-carnitine is a member of the class of compounds known as acylcarnitines. Isobutyryl-L-carnitine is a product of the acyl-CoA dehydrogenases.
|
T13339 |
Wf-516
|
310392-94-0
|
98%
|
|
Wf-516 is a 5-HT reuptake inhibitor (Kis: 5 nM and 40 nM for 5-HT1A receptor and 5-HT2A receptor in humans, respectively), and with potent antidepressant activit...
|
TN4713 |
Onitisin
|
53823-03-3
|
98%
|
|
Onitisin, onitinoside and onitin can inhibit the contraction of isolated guinea-pig ileum.
|
T10380 |
AS19
|
1000578-26-6
|
98%
|
|
AS19 is a potent, selective 5-HT7 receptor agonist (IC50: 0.83 nM; Ki: 0.6 nM). AS19 is selective for 5-HT7 over 5-HT1A, 5-HT1B, 5-HT1D, and 5-HT5A receptors (Ki...
|
T15026 |
Cyamemazine
|
3546-03-0
|
98%
|
|
Cyamemazine, contains the phenothiazine chromophore, is a neuroleptic agent used as an anxiolytic. Cyamemazine is a potent 5-HT3 (Ki: 12 nM), 5-HT2A (Ki: 1.5 nM)...
|
T13021 |
Sulamserod
|
219757-90-1
|
98%
|
|
Sulamserod is an antagonist of 5-HT4 receptor, has antiarrhythmic activities.
|
T16433 |
Pancopride
|
121650-80-4
|
98%
|
|
Pancopride is a new effective and selective antagonist of the 5-HT3 receptor.
|
T12262L |
NPS ALX Compound 4a dihydrochloride
|
1781934-44-8
|
98%
|
|
NPS ALX Compound 4a dihydrochloride is a potent and selective antagonist of 5-HT6 receptor (IC50 of 7.2 nM)
|
T10114 |
3-Hydroxy agomelatine
|
166526-99-4
|
98%
|
|
3-Hydroxy agomelatine is an Agomelatine metabolite and a 5-HT2C receptor antagonist (IC50: 3.2 μM; Ki: 1.8 μM).
|