T22296 |
Cisapride hydrate
|
260779-88-2
|
98%
|
|
Cisapride acts directly as a selective agonist of serotonin 5-HT4 receptor with IC50 value of 0.483 μM. And It also acts indirectly as a parasympathomimetic.
|
T10371 |
Arotinolol
|
68377-92-4
|
98%
|
|
Arotinolol is a nonselective α/β-adrenergic receptor blocker and a vasodilating β-blocker. Arotinolol also shows potency for inhibiting the binding of the radiol...
|
T10075L |
2-Methyl-5-HT maleate
|
78263-91-9
|
98%
|
|
2-Methyl-5-HT maleate (2-Methyl-5-hydroxytryptamine maleate) is a potent and selective 5-HT3 receptor agonist, which is shown to display anti-depressive-like eff...
|
T11293 |
(±)-Fabesetron hydrochloride
|
129299-81-6
|
98%
|
|
FK1052 hydrochloride is a potent 5-HT3 and 5-HT4 receptor dual antagonist.
|
T12489L |
Pimethixene maleate
|
13187-06-9
|
98%
|
|
Pimethixene maleate is a highly potent5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, histamine H1, dopamine D2 and D4.4 as well as muscarinic M1 and M2 receptors antagonist(wit...
|
T10495 |
Befiradol hydrochloride (208110-64-9 free base)
|
2436760-81-3
|
98%
|
|
Befiradol (NLX-112) hydrochloride is a selective agonist of the 5-HT1A receptor.
|
TN3235 |
7-Hydroxycadalene
|
2102-75-2
|
98%
|
|
7-Hydroxycadalene shows cytotoxicity activity against HCT-15 cell line with IC50 18.89 ± 1.2 uM.
|
T11302 |
Flumexadol
|
30914-89-7
|
98%
|
|
Flumexadol is a selective and affinity 5-HT2C receptor agonist with a Ki of 25 nM for the (+)-enantiomer of Flumexadol, and is 40-fold selective over the 5-HT2A ...
|
TN4092 |
Galanolactone
|
115753-79-2
|
98%
|
|
Galanolactone has anti-5-HT effect, a diterpenoid isolated from ginger, is related to antagonism of 5-HT3 receptors, it has inhibit nitric oxide production with ...
|
T12632L |
(S)-Mirtazapine
|
61337-87-9
|
98%
|
|
(S)-Mirtazapine is an S(+)-enantiomer of Mirtazapine. (S)-Mirtazapine is a stereoselective 5-HT2 receptor antagonist.
|
T1769 |
Pardoprunox
|
269718-84-5
|
98%
|
|
Pardoprunox is a partial dopamine D2 agonist and noradrenergic agonist with serotonin 5-HT1A agonist properties. Pardoprunox has been used in trials studying the...
|
T12215 |
Nexopamil racemate
|
116759-35-4
|
98%
|
|
Nexopamil racemate is the racemate of Nexopamil. Nexopamil is a combined Ca2+/5-HT2 antagonist on platelet aggregation in vitro and on thrombus formation in vivo...
|
T12842 |
SB-269970
|
201038-74-6
|
98%
|
|
SB-269970 is a antagonist of 5-HT7 receptor(pKi of 8.3).
|
T10075L2 |
2-Methyl-5-HT hydrochloride
|
845861-49-6
|
98%
|
|
2-Methyl-5-HT hydrochloride (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist with anti-depressive-like effects.
|
T4375 |
Methiothepin maleate
|
19728-88-2
|
98%
|
|
Methiothepin is a 5-HT1, 5-HT6, 5-HT7 serotonin receptor antagonist, which blocks serotonin autoreceptors.
|
T12262 |
NPS ALX Compound 4a
|
299433-10-6
|
98%
|
|
NPS ALX Compound 4a is a potent and selective antagonist of 5-HT6 receptor (IC50 of 7.2 nM)
|
TQ0315 |
Tandospirone
|
87760-53-0
|
98%
|
|
Tandospirone (SM-3997) is a selective partial agonist of 5-HT1A receptor (Ki: 27 nM) that displays selectivity over SR-2, SR-1C, α1, α2, D1 and D2 receptors (Kis...
|
T10498 |
5-HT2A antagonist 1
|
204643-75-4
|
98%
|
|
5-HT2A antagonist 1 is a 5-HT2A antagonist extracted from patent US5728835A and JP 1007727. It may be useful in the treatment of gastrointestinal disorders circu...
|
T10267 |
Agomelatine (L(+)-Tartaric acid)
|
824393-18-2
|
98%
|
|
Agomelatine (S-20098) L(+)-Tartaric acid is a specific agonist of MT1 and MT2 receptors (Kis: 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and ...
|
T12631 |
(R)-Mirtazapine D3
|
T12631
|
98%
|
|
(R)-Mirtazapine D3 is a deuterium labeled (R)-Mirtazapine.(R)-Mirtazapine is a antagonist of 5-HT3 receptor.
|