5-HT Receptor

5-hydroxytryptamine receptors or 5-HT receptors, or serotonin receptors, are a group of G protein-coupled receptor and ligand-gated ion channels found in the central and peripheral nervous systems. They mediate both excitatory and inhibitory neurotransmission.

Cat. No.	Product name	CAS No.	Purity
T0039	Dapoxetine	119356-77-3	99.76%
T0039	Dapoxetine is a selective serotonin reuptake inhibitor, for the treatment of premature ejaculation.
T3086	Mesoridazine Besylate	32672-69-8	99.27%
T3086	Mesoridazine (Serentil) is a piperidine neuroleptic drug belonging to the class of drugs called phenothiazines, used in the treatment of schizophrenia. It is a m...
T62269	F 14679	208109-38-0	99.09%
T62269	F 14679 is a potent 5-HT1A agonist (pKi=10.23) with a maximum Ca2t response similar to 5-HT.
T28414	Piclozotan	182415-09-4	99%
T28414	Piclozotan (anhydrous), a 5-HT1A receptor agonist, demonstrated significant neuroprotective activity in a transient middle cerebral artery occlusion (t-MCAO) mod...
T4348	Syk Inhibitor II	726695-51-8	97.63%
T4348	Syk inhibitor II, a cell-permeable, ATP-competitive, pyrimidine-carboxamide compound, selectively and reversibly inhibits Syk (IC50 = 41 nM).
T8702	SKF-83566	99295-33-7	95.00%
T8702	SKF-83566 is a blood-brain permeable and orally active antagonist of D1-like dopamine receptor and a weaker competitive 5-HT2 receptor antagonist with Ki of 11 n...
T1769	Pardoprunox	269718-84-5
T1769	Pardoprunox is a partial dopamine D2 agonist and noradrenergic agonist with serotonin 5-HT1A agonist properties. Pardoprunox has been used in trials studying the...
TN1415	Auraptenol	1221-43-8	98%
TN1415	Auraptenol possesses robust antidepressant-like efficacy in mice.
T15100	Desmethyl cariprazine	839712-15-1	98%
T15100	Desmethyl cariprazine is a Cariprazine active metabolite. Cariprazine, an antipsychotic drug candidate, shows a high affinity for the D3 (Ki: 0.085 nM) and D2 (K...
T17095	TIK-301	118702-11-7	98%
T17095	TIK-301 is a chlorinated melatonin derivative and a potent, high-affinity, and orally active melatonin MT1 and MT2 receptors agonist (Kis: 0.081 nM and 0.042 nM,...
T11949	Masupirdine mesylate	1791396-46-7	98%
T11949	Masupirdine mesylate (SUVN-502 mesylate) shows high selectivity over 5-HT2A receptor and other 100 target sites, and has potential for treatment of Alzheimer's d...
T19381	Isobutyryl-L-carnitine	25518-49-4	98%
T19381	Isobutyryl-L-carnitine is a member of the class of compounds known as acylcarnitines. Isobutyryl-L-carnitine is a product of the acyl-CoA dehydrogenases.
T13339	Wf-516	310392-94-0	98%
T13339	Wf-516 is a 5-HT reuptake inhibitor (Kis: 5 nM and 40 nM for 5-HT1A receptor and 5-HT2A receptor in humans, respectively), and with potent antidepressant activit...
TN4713	Onitisin	53823-03-3	98%
TN4713	Onitisin, onitinoside and onitin can inhibit the contraction of isolated guinea-pig ileum.
T10380	AS19	1000578-26-6	98%
T10380	AS19 is a potent, selective 5-HT7 receptor agonist (IC50: 0.83 nM; Ki: 0.6 nM). AS19 is selective for 5-HT7 over 5-HT1A, 5-HT1B, 5-HT1D, and 5-HT5A receptors (Ki...
T15026	Cyamemazine	3546-03-0	98%
T15026	Cyamemazine, contains the phenothiazine chromophore, is a neuroleptic agent used as an anxiolytic. Cyamemazine is a potent 5-HT3 (Ki: 12 nM), 5-HT2A (Ki: 1.5 nM)...
T13021	Sulamserod	219757-90-1	98%
T13021	Sulamserod is an antagonist of 5-HT4 receptor, has antiarrhythmic activities.
T16433	Pancopride	121650-80-4	98%
T16433	Pancopride is a new effective and selective antagonist of the 5-HT3 receptor.
T12262L	NPS ALX Compound 4a dihydrochloride	1781934-44-8	98%
T12262L	NPS ALX Compound 4a dihydrochloride is a potent and selective antagonist of 5-HT6 receptor (IC50 of 7.2 nM)
T10114	3-Hydroxy agomelatine	166526-99-4	98%
T10114	3-Hydroxy agomelatine is an Agomelatine metabolite and a 5-HT2C receptor antagonist (IC50: 3.2 μM; Ki: 1.8 μM).