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Cat No. | Product Name | Synonyms | Targets |
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T22774L | Eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species](TFA) | Others | |
eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species](TFA) is Elongation factor 1 subunit.eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) encodes an isoform of the alpha sub... | |||
T72013 | Epigenetic Multiple Ligand | ||
Epigenetic Multiple Ligand is a cell-permeable inhibitor of substrate processing by several chromatin-associated enzymes, including SIRT1/2, H3/SET7, H3/p300/CBP, H4/RmtA, PABP1/CARM1, and H4/PRMT1. It acts by inducing e... | |||
TP2269 | MAP kinase fragment [Multiple species] | Others | |
This Mitogen-activated protein kinase (MAP kinase) fragment has a peptide sequence of Lys-Tyr-Ile-His-Ser-Ala-Asn-Val-Leu. The MAP kinases are serine/threonine-specific protein kinases belonging to the CMGC (CDK/MAPK/GSK... | |||
TP2248 | Ferritin heavy chain fragment [Multiple species] | Others | |
Ferritin is a protein of 450 kDa consisting of 24 subunits that is present in every cell type. Invertebrates, these subunits are both the light (L) and the heavy (H) type with an apparent molecular weight of 19 kDA or 21... | |||
T22774 | Eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species] | Others | |
eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. ... | |||
T9745 | Elevenostat | HDAC | |
Elevenostat is an HDAC11-selective inhibitor with an IC50 value of 0.235 µM. | |||
T6800 | CCF642 | AC1LYELL | Others |
CCF642 (AC1LYELL) is a novel PDI-inhibiting compound with antimyeloma activity. | |||
TP2315 | Glatiramer Acetate | Others | |
Glatiramer acetate (GA) is a synthetic amino acid copolymer that is approved for treatment of relapsing remitting multiple sclerosis (RRMS) and clinically isolated syndrome (CIS). | |||
T22277 | BMS-P5 | PAD | |
BMS-P5 is a specific and orally active Peptidylarginine Deiminase 4 (PAD4) inhibitor. | |||
T9370 | DCBP-1 | Epigenetic Reader Domain , Ligand for E3 Ligase | |
dCBP-1 is a chemical degrader of p300/CBP. dCBP-1 hijacks the E3 ubiquitin ligase CRBN for selective degradation of p300/CBP. Degradation of p300/CBP by dCBP-1 leads to effective multiple myeloma cell killing. | |||
T5484 | GSK467 | Histone Demethylase , Histone Methyltransferase | |
GSK467 is a potent and selective inhibitor of KDM5 (JARID1)(Ki : 10 nM). | |||
T3971 | CASIN | Pirl1-related Compound 2 | CDK , STAT , Ras |
CASIN (Pirl1-related Compound 2) is a specific inhibitor of GTPase Cdc42 (IC50: 2 uM). | |||
T6796 | CB-5083 | CB5083,CB 5083 | p97 |
CB-5083 is a potent, selective, and orally bioavailable p97 AAA ATPase inhibitor ( IC50=11 nM). | |||
T10096L | Voruciclib | CDK | |
Voruciclib is an orally active and selective CDK inhibitor (Ki: 0.626 nM-9.1 nM). Voruciclib represses the expression of MCL-1 in multiple models of diffuse large B-cell lymphoma. Voruciclib effectively blocks CDK9, the ... | |||
T12871 | Talmapimod | SCIO-469 | p38 MAPK |
Talmapimod (SCIO-469) is an selective, orally active, and ATP-competitive p38α inhibitor with IC50 of 9 nM and 90 nM for p38α and p38β, respectively. Talmapimod exhibits at least 2000-fold selectivity over a panel of 20 ... | |||
T4283 | SRI-011381 | TGF-beta/Smad | |
SRI-011381, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease. | |||
T41290 | MST-312 | Telomerase Inhibitor IX | Telomerase |
MST-312 (Telomerase Inhibitor IX) is a derivative of green tea epigallocatechin gallate (EGCG). MST-312 is a telomerase inhibitor. MST-312 has research value in cancer, such as multiple myeloma (MM). | |||
T9573 | GSK3685032 | DNA Methyltransferase | |
GSK3685032 is a non-covalent and selective DNMT1 inhibitor(IC50 = 36 nM). The inhibitory effect is time-independent and reversible. GSK3685032 induces loss of DNA methylation and transcriptional activation and inhibits c... | |||
T22277L | BMS-P5 free base | PAD | |
BMS-P5 free base is a specific and orally active peptidylarginine deiminase 4 (PAD4) inhibitor. BMS-P5 Blocks Formation of Neutrophil Extracellular Traps and Delays Progression of Multiple Myeloma. Administration of BMS-... | |||
T9125 | Tolebrutinib | PRN2246,SAR442168 | BTK |
Tolebrutinib (PRN2246) is a potent, selective, orally active and brain-penetrant Bruton tyrosine kinase (BTK) inhibitor(IC50s of 0.4 and 0.7 nM in Ramos B cells and in HMC microglia cells, respectively). It exhibits effi... | |||
T8342 | BRD9876 | Others , Kinesin , Microtubule Associated | |
BRD9876 is a selective inhibitor of MM1S growth. | |||
T22922 | Lenalidomide hemihydrate | TNF , Ligand for E3 Ligase , Molecular Glues | |
Lenalidomide hemihydrate is a TNF-α secretion inhibitor (IC50 = 13 nM). Lenalidomide hemihydrate could bound endogenous CRBN and recombinant CRBN-DNA damage binding protein-1 (DDB1) complexes. | |||
T7779 | Nelfinavir | AG1341 | HIV Protease |
Nelfinavir (AG1341) is an antiretroviral drug used in the treatment of the human immunodeficiency virus (HIV) (Ki=2 nM). Nelfinavir is a broad-spectrum, anticancer agent. | |||
T0029 | Procaine | Duracaine,Spinocaine,Novocaine,Vitamin H3 | Histone Demethylase , DNA/RNA Synthesis , Sodium Channel |
Procaine (Vitamin H3) is a local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. | |||
T8719 | SC99 | Apoptosis , JAK , STAT | |
SC99 is a selective inhibitor of JAK2-STAT3 activation. SC99 downregulates the expression of STAT3-modulated genes.SC99 inhibits platelet activation, aggregation and displays potent anti-myeloma, anti-thrombotic activiti... | |||
T13408 | ZK824190 | Others , Serine Protease | |
ZK824190 is an orally available and selective inhibitor of urokinase plasminogen activator (uPA) as a potential treatment for multiple sclerosis(IC50s of 237, 1600 and 1850 nM for uPA, tPA, and Plasmin, respectively). | |||
T0802 | Procaine hydrochloride | Novocaine HCl,Procaine HCl | Histone Demethylase , 5-HT Receptor , DNA/RNA Synthesis , Sodium Channel , NMDAR , AChR |
Procaine hydrochloride (Novocaine HCl) is the hydrochloride salt form of procaine, a benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds to and inhibits voltage-gated sodiumchannel... | |||
T6403 | Siponimod | BAF-312 | S1P Receptor , LPL Receptor |
BAF312 (Siponimod (BAF-312)), a next-generation S1P receptor modulator, is specific for S1P1 and S1P5 receptors with EC50 of 0.39 nM and 0.98 nM, respectively. The specificity of BAF312 for S1P1 and S1P5 receptors exhibi... | |||
T6312 | R547 | Ro 4584820 | Apoptosis , GSK-3 , PKA , CDK |
R547 (Ro 4584820) is a potent ATP-competitive inhibitor of CDK1/2/4 with Ki of 2 nM/3 nM/1 nM. It is less potent to CDK7 and GSK3α/β, while inactive to other kinases. Phase 1. | |||
T3661 | Citarinostat | ACY241,HDAC-IN-2 | HDAC |
ACY-241, also known as Citarinostat (ACY241), is a potent, selective and orally available histone deacetylase (HDAC) inhibitor, with potential antineoplastic activity. Upon oral administration, ACY-241 inhibits the activ... | |||
T6923 | Ozanimod | RPC-1063 | S1P Receptor , LPL Receptor |
Ozanimod (RPC-1063) (RPC1063) is a specific oral S1P Receptor 1 modulator. Ozanimod has been used in trials studying the treatment of Crohn's Disease, Ulcerative Colitis, Multiple Sclerosis, and Relapsing Multiple Sclero... | |||
T4031 | S1p receptor agonist 1 | S1p-receptor-agonist-1 | S1P Receptor , LPL Receptor |
S1p receptor agonist 1 (S1p-receptor-agonist-1) is an S1P receptor agonist. | |||
T1642 | Lenalidomide | CC-5013 | Apoptosis , TNF , Ligand for E3 Ligase , Molecular Glues |
Lenalidomide (CC-5013) is a potent inhibitor of TNF-α that, at 10 μM, alters gene expression and cell viability in a range of cancer cell lines. | |||
T6561 | Laquinimod | LAQ,ABR-215062 | Apoptosis , Others , NF-κB |
Laquinimod (LAQ) is an effective immunomodulator, which is currently under development in phase III trials for the treatment of multiple sclerosis as an oral therapy. | |||
T1979 | AVN-944 | VX-944 | Dehydrogenase |
AVN-944 (VX-944)(VX-944) is a selective, noncompetitive inhibitor of human IMPDH with Ki of 6-10 nM for IMPDH1/IMPDH2. | |||
T5129 | SRI-011381 hydrochloride | SRI-011381 hydrochloride [1629138-41-5(free base)] | TGF-beta/Smad |
SRI-011381 hydrochloride, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease. | |||
T7791 | Iberdomide | CC-220 | Apoptosis , Ligand for E3 Ligase |
Iberdomide (CC-220) is a modulator of cereblon( IC50 value of 60 nM in a competitive TR-FRET assay). | |||
T4134 | OTS514 hydrochloride | OTS-514 hydrochloride,OTS514 hydrochloride(1338540-63-8(free base)) | Apoptosis , TOPK |
OTS514 hydrochloride is a highly effective TOPK(T-LAK cell-originated protein kinase) inhibitor (IC50: 2.6 nM). | |||
T6079 | NVP-ADW742 | ADW742,ADW,GSK 552602A | Apoptosis , IGF-1R |
NVP-ADW742 (ADW) is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-Abl and c-Kit. | |||
T2558 | Cladribine | 2-chlorodeoxyadenosine,2-Chloro-2′-deoxyadenosine,CldAdo,2CdA | Apoptosis , Adenosine deaminase |
Cladribine (2CdA), an adenosine deaminase inhibitor, is utilized in the treatment of lymphoproliferative diseases. | |||
T6001 | Nelfinavir Mesylate | Viracept,Nelfin,AG1343,AG 1343 Mesylate | HIV Protease |
Nelfinavir Mesylate (Viracept) is an effective HIV protease inhibitor (Ki: 2 nM). | |||
T1776 | Plerixafor | JM3100,AMD 3100,AMD-3329 | Virus Protease , HIV Protease , CXCR |
Plerixafor (AMD-3329), a chemokine receptor antagonist, blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4. | |||
T2241 | Alisertib | MLN 8237 | Apoptosis , Aurora Kinase , Autophagy |
Alisertib (MLN 8237) is a specific Aurora A inhibitor (IC50: 1.2 nM). The selectivity of Alisertib(MLN 8237) is >200-fold higher for Aurora A than Aurora B. | |||
T21503 | (E/Z)-Zotiraciclib | (E/Z)-TG02,(E/Z)-SB1317 | FLT , JAK , CDK |
(E/Z)-Zotiraciclib ((E/Z)-TG02) inhibits CDK2, JAK2, and FLT3 effectively with IC50s of 13, 73, and 56 nM, respectively. | |||
TP1540 | Jagged-1 (188-204) | Jagged-1 188-204 | Gamma-secretase |
Jagged-1 (188-204)is a fragment of the JAG-1 protein. JAG-1 is Notch ligand, a peptide that is the most conspicuously expressed ligand in skin. JAG-1 induces epidermal maturation. Exposing submerged keratinocytes monolay... | |||
T4134L | OTS514 | OTS514 HCl,OTS514 Hydrochloride,OTS-514,OTS 514 | Apoptosis , TOPK |
OTS514 (OTS514 Hydrochloride) is a potent TOPK inhibitor. OTS514 exhibits a growth-suppressive effect on small cell lung cancer. OTS514 effectively suppressed the growth of SCLC cell lines (IC50: 0.4 ~ 42.6 nM). Treatmen... | |||
T11141 | E64FC26 | Others | |
E64FC26 is a potent protein disulfide isomerase (PDI) family pan-inhibitor with antitumor activity, inhibits PDIA1, PDIA3, PDIA4, TXNDC5 and PDIA6, and can be used in the study of multiple myeloma and pancreatic cancer. | |||
T14918 | CDK9-IN-2 | Others , CDK | |
CDK9-IN-2 is a special CDK9 inhibitor and has an IC50 of 5 nM and 7 nM in A2058 skin cell line (72 hours) and H929 multiple myeloma cell line (72 hours), respectively. | |||
T60021 | EcMetAP-IN-1 | Others | |
ecMetAP-IN-1 can be used as a QSAR model to study methionine aminopeptidase inhibitor as an anticancer agent using multiple linear regression. | |||
T19533 | Pyraclonil | Others | |
Pyraclonil, a herbicide agent, effectively controls susceptible (S) and multiple-herbicide-resistant (MHR) E. indica populations as it acts as a proporphyrinogen oxidase (PPO) inhibitor. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T4903 | Heptadecanoic acid | Others , Endogenous Metabolite | |
Heptadecanoic acid is a fatty acid of exogenous (primarily ruminant) origin. Many "odd" length long chain amino acids are derived from the consumption of dairy fats (milk and meat). Heptadecanoic acid constitutes 0.61% o... | |||
T2844 | Hyperoside | Quercetin 3-galactoside,Hyperin | Others , Influenza Virus , Antifungal |
Hyperoside (Hyperin) is a naturally occuring flavonoid compound which shows multiple bioactivities, including myocardial protection, anti-redox, and anti-inflammatory activities. | |||
T17048 | Tetradecanoylcarnitine | L-Myristoylcarnitine,Myristoyl-L-(-)-carnitine | Endogenous Metabolite |
Tetradecanoylcarnitine (L-Myristoylcarnitine) is an acylcarnitine involved in the beta-oxidation of long-chain fatty acids, and is a potential marker for very-long-chain coenzyme A dehydrogenase deficiency. alpha-Dihydro... | |||
T13768 | (+)-Medicarpin | Estrogen/progestogen Receptor | |
(+)-Medicarpin, a pterocarpan, is an isoflavonoid compound derived from multiple medicinal plant species such as Sophora japonica, Zollernia paraensis, Platymiscium yucatamun, Machaerium aristulatum, and Platymiscium flo... | |||
T4784 | (S)-(-)-Phenylethanol | (S)-(-)-1-Phenylethanol,(-)-Methyl phenyl carbinol,(S)-(-)-sec-Phenylethyl alcohol | Others , Endogenous Metabolite |
(S)-(-)-Phenylethanol ((-)-Methyl phenyl carbinol) exists as a solid, soluble (in water), and a very weakly acidic compound (based on its pKa). (S)-(-)-Phenylethanol has been detected in multiple biofluids, such as feces... | |||
T5S1026 | Apigenin-7-glucuronide | Apigenin 7-O-glucuronide | MMP |
Apigenin-7-glucuronide (Apigenin 7-O-glucuronide) possesses multiple activities, including antioxidant, anti-inflammatory, and aldose reductase inhibitory activities, it can inhibit MMP activities (IC50s: 12.87, 22.39, 1... | |||
T3002 | Piperine | 1-Piperoylpiperidine,Bioperine | P450 , Endogenous Metabolite , P-gp , Autophagy |
Piperine (Bioperine) , a alkaloid, has been used in trials studying the treatment of multiple myeloma and deglutition disorders. | |||
T5239 | Cholesteryl sulfate sodium | Cholesterol 3-Sulfate Sodium Salt,Sodium Cholesteryl Sulfate | Endogenous Metabolite , PKC |
Cholesteryl sulfate sodium (Sodium Cholesteryl Sulfate) is a sterol sulfate in human plasma. Cholesteryl sulfate sodium is a component of cell membrane and has a regulatory function. Cholesteryl sulfate sodium also activ... | |||
T4808 | Agmatine sulfate | Agmatine sulfate salt | Endogenous Metabolite , NO Synthase , Imidazoline Receptor |
Agmatine sulfate (Agmatine sulfate salt) is a bioactive metabolite of the arginine amino acid. It exerts modulatory action at multiple molecular targets, such as neurotransmitter systems, ion channels and nitric oxide sy... | |||
T1166 | Ellipticine | NSC 71795,Elliptisine | Topoisomerase |
Ellipticine (Elliptisine) is a potent antineoplastic agent exhibiting multiple mechanisms of action, IC50 of 0.67±0.06, 1.25±0.13, 1.25±0.13, 0.67±0.06, 0.27±0.02, 0.49±0.04, 0.44±0.03, and 1.48±0.62 μM for Leukemia HL-6... | |||
T5273 | 2-Hydroxy-3-methylbutanoic acid | 2-Hydroxy-3-methylbutyric acid,2-Hydroxyisovaleric Acid,(±)-2-Hydroxyisopentanoic Acid | Others , Endogenous Metabolite |
2-Hydroxy-3-methylbutanoic acid ((±)-2-Hydroxyisopentanoic Acid) is a metabolite found in the urine of patients with phenylketonuria, methylmalonic acidemia, propionic acidemia, 3-ketothiolase deficiency, isovaleric acid... | |||
T5530 | Mithramycin A | Plicamycin | DNA/RNA Synthesis |
Mithramycin A (Plicamycin), a DNA-binding antitumor antibiotic, is a selective specificity protein 1 (Sp1) inhibitor, which inhibits the growth of various cancers by decreasing Sp1 protein. Specificity protein 1 (Sp1) is... | |||
T3398 | Icaritin | Anhydroicaritin,Cycloicaritin | Apoptosis , JAK , STAT , Autophagy |
Icaritin (Anhydroicaritin) has hormone regulation activity and cardiovascular function improvement activity. Icaritin has anticancer activity, can induce S phase arrest and apoptosis, inhibit ENKL cell proliferation. Ica... | |||
T3752 | 4-Hydroxybenzyl alcohol | 4-Methylolphenol,P-Methylolphenol | Apoptosis , Endogenous Metabolite |
4-Hydroxybenzyl alcohol (P-Methylolphenol) exhibits beneficial effects in cerebral ischemic injury, has neuroprotective effect through upregulation of Nrf2, Prdx6, and PDI expression via the PI3K/Akt pathway. 4-Hydroxybe... | |||
T4798 | N-Acetyl-L-leucine | Others , Endogenous Metabolite | |
N-Acetylleucine belongs to the class of organic compounds known as leucine and derivatives. Leucine and derivatives are compounds containing leucine or a derivative thereof resulting from reaction of leucine at the amino... | |||
T3851 | Vicenin 2 | Vicenin -2 | RAAS |
Vicenin 2 is an angiotensin-converting enzyme (ACE) inhibitor (IC50=43.83 μM) from the aerial parts of Desmodium styracifolium. Vicenin 2 is an inhibitor of α-glucosidase, PTP1B, and RLAR. Vicenin 2 has hepatoprotective,... | |||
T4S1469 | Cucurbitacin IIb | Apoptosis , Others | |
1. Cucurbitacin IIb is one of the major active compounds in Hemsleyadine tablets which have been used for clinical treatment of bacillary dysentery, enteritis and acute tonsilitis. 2. Cucurbitacin IIb exhibits its anti-i... | |||
T4855 | Tricosanoic acid | Tricosan-1-oic acid | Endogenous Metabolite |
Tricosanoic acid (Tricosan-1-oic acid) , also known as N-tricosanoate or tricosylate, belongs to the class of organic compounds known as very long-chain fatty acids.Tricosanoic acid has been detected in multiple biofluid... | |||
T4837 | Itaconic acid | methylene-butanedioicaci | Others , Endogenous Metabolite |
Itaconic acid (methylene-butanedioicaci), also known as itaconate, belongs to the class of organic compounds known as branched fatty acids. These are fatty acids containing a branched chain. Itaconic acid exists as a sol... | |||
T4707 | 3-Hydroxyanthranilic acid | 3-HYDROXY-2-AMINOBENZOIC ACID | Others , Endogenous Metabolite |
3-Hydroxyanthranilic acid (3-HYDROXY-2-AMINOBENZOIC ACID), also known as 2-amino-3-hydroxy-benzoate or 3-ohaa, belongs to the class of organic compounds known as hydroxybenzoic acid derivatives. 3-Hydroxyanthranilic acid... | |||
T19504 | Paullinic acid | Others | |
Paullinic acid is a long-chain fatty acid that has been detected in multiple biofluids. | |||
T12403 | Penitrem A | Others | |
Penitrem A is a selective antagonist of BK channel with antiproliferative and anti-invasive activities against multiple malignancies. | |||
T31911 | Ganodermic acid S | Ganoderic acid R | |
Ganodermic acid S, as a membrane acting agent isolated from the fungus Ganoderma lucidum, exerts multiple effects on human platelet function. | |||
TN4732 | Pachysamine M | Others | |
Pachysamine M shows inhibitory activities against multiple types of cancer cells. | |||
TN1973 | Naringenin triacetate | Others | |
Naringenin triacetate exhibits a better binding affinity with multiple crystal structures of first bromodomain BRD4 (BRD4 BD1) when compared with the known inhibitors. | |||
TN3627 | Chalepensin | ATPase , NADPH-oxidase , P450 , Antifection | |
Chalepensin behaves as an energy transfer inhibitor at low concentration, it inhibits multiple P450s and that epoxidation activity is crucial for the potential drug interaction through mechanism-based inhibition. Chalepe... | |||
TN5369 | Dehydroleucodine | Dehydroleucodin | |
Dehydroleucodine has antidiarrheal, anti-inflammatory, anti-microbial, embryotoxicity, gastric cytoprotective, anti-cancer activities. Dehydroleucodine has an important inhibitory effect in cellular pathways regulating a... | |||
T82070 | Ingol 7,8,12-triacetate 3-(4-methoxyphenyl)acetate | ||
Ingol 7,8,12-triacetate 3-(4-methoxyphenyl)acetate, a complex ingol diterpene derived from the latex of Euphorbia officinarum, features multiple acetate functional groups [1]. | |||
TN4016 | Ethyl 2,4,6-trihydroxybenzoate | Liver X Receptor | |
Ethyl 2,4,6-trihydroxybenzoate is a dual-LXR modulator that regulates the expression of key genes in cholesterol homeostasis in multiple cells without inducing lipid accumulation in HepG2 cells. It suppresses cellular ch... | |||
T78539 | (+)-Coclaurine hydrochloride | d-Coclaurine hydrochloride,(R)-Coclaurine hydrochloride,(+)-(R)-Coclaurine hydrochloride | Others |
(+)-Coclaurine hydrochloride, also known as (+)-(R)-Coclaurine, is a benzyltetrahydroisoquinoline alkaloid extracted from multiple plant species. This compound exhibits anti-aging properties, as reported in sources [1] [... | |||
T74200 | Glicophenone | ||
Glicophenone, an antibacterial agent, demonstrates minimum inhibitory concentrations (MICs) of 32 μg/mL against multiple strains, including MRSA OM481, MRSA OM505, MRSA OM584, MRSA OM623, and MSSA 209P [1]. | |||
T11202 | Enniatin complex | Others | |
Enniatin complex, a mixture of cyclohexadepsipeptides predominantly derived from various Fusarium species of fungi, exhibits inhibitory effects on enzymes such as acyl-CoA: cholesterol acyl transferase. Furthermore, it h... | |||
TN5129 | Tetrahydro tanshinone I | Others | |
Tetrahydro tanshinone I is one compound of Fufang Danshen Prescription (FDP) , liposome equilibrium dialysis system could simply and effectively esti-mate the absorption of multiple components in FDP in vivo, and predict... | |||
T73925 | α-D-Glucose-1-phosphate disodium hydrate | ||
α-D-Glucose-1-phosphate disodium hydrate serves multiple roles in medical and biochemical applications, including as a precursor in the synthesis of glucuronic acid, a cytostatic compound crucial for cardiopathic therapy... | |||
TN5280 | (-)-Zeylenol | Zeylenol | Apoptosis |
(-)-Zeylenol (Zeylenol) is a natural product derived from the stems of the Uvaria grandiflora, showing anti-inflammatory, antifeedant and antitumor biological activity, acting by inhibiting the synthesis or release of mu... | |||
T78506 | α-Lactose hydrate | α-D-Lactose hydrate | |
α-Lactose (hydrate) (α-D-Lactose (hydrate)), the main carbohydrate in mammalian milk, comprises two sugar units: glucose and galactose, and occurs as two anomers, α and β. It serves multiple roles in the food and pharmac... | |||
T70495 | Scytonemin | ||
Scytonemin is a biological pigment synthesized by many strains of cyanobacteria, including Calothrix sp., Lyngbya aestuarii, and others. Scytonemin is also a potent PKL1 inhibitor, which inhibits cell proliferation and a... | |||
T77242 | Pectin | ||
Pectin, a heteropolysaccharide extracted from the cell wall of higher plants, plays multiple roles; it forms nanoparticles for agent delivery, acts as an adsorbent, and serves as a broad-spectrum antimicrobial agent. It ... | |||
TN1694 | Gliotoxin | Apoptosis , NF-κB , Wnt/beta-catenin , COX , PKA , Antibacterial , Antifection | |
Gliotoxin, a Wnt signaling pathway inhibitor, induces growth inhibition and apoptosis in multiple colorectal cancer cell lines with mutations of the Wnt signaling pathway. | |||
TN4286 | Isodunnianol | NOS , NF-κB , ROS , AChR | |
Isodunnianol exhibits anti-AChE activity with an IC50 value of 13.0 uM; it also exhibits neurite outgrowth-promoting activity at the concentration ranging from 0.1 to 10 uM in the primary cultured rat cortical neurons. I... | |||
TN4838 | Pseurotin A | Antifection | |
Pseurotin A has immunosuppressive activity, it inhibits immunoglobulin E(IgE) production in vitro.It shows a moderate effect against the phytopathogenic bacteria Erwinia carotovora and Pseudomonas syringae, with IC50 val... | |||
T38179 | C16 3'-sulfo Galactosylceramide (d18:1/16:0) | C16 3'-sulfo Galactosylceramide (d18:1/16:0) | Others |
C16 3'-sulfo Galactosylceramide (d18:1/16:0) is a sulfated glycolipid.C16 3'-sulfo Galactosylceramide (d18:1/16:0) is a relatively abundant sulfide found in porcine brain and plasma that decreases throughout development ... | |||
T83916 | Cytogenin | ||
Cytogenin, a coumarin derivative isolated from S. eurocidicum, exhibits multiple biological effects. It notably diminishes tumor mass in an Ehrlich murine spontaneous adenocarcinoma model with a daily administration of 2... | |||
T36915 | 21-Deoxycortisol | ||
21-Deoxycortisol is a corticosteroid metabolite of 17-hydroxyprogesterone produced in the adrenal glandvia11-hydroxylation by 11β-hydroxylase.1,2Serum levels of 21-deoxycortisol are elevated in patients with congenital a... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-05162 | MEGF10 Protein, Human, Recombinant (hFc) | Human | HEK293 |
MEGF10 (Multiple EGF Like Domains 10) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. This gene encodes a member of the multiple epidermal growth factor-like domains protein family. T... | |||
TMPY-04301 | MEGF10 Protein, Human, Recombinant (His) | Human | HEK293 |
MEGF10 (Multiple EGF Like Domains 10) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. This gene encodes a member of the multiple epidermal growth factor-like domains protein family. T... | |||
TMPY-04647 | EGFL6 Protein, Human, Recombinant (His & FLAG) | Human | Baculovirus-Insect Cells |
EGFL6, also known as EGF-L6, belongs to the epidermal growth factor (EGF) repeat superfamily. Members of this superfamily are characterized by the presence of EGF-like repeats and are often involved in the regulation of ... | |||
TMPY-02178 | EGFL7 Protein, Mouse, Recombinant (His) | Mouse | Baculovirus-Insect Cells |
Epidermal growth factor-like protein 7, also known as EGF-like protein 7, Multiple epidermal growth factor-like domains protein 7, Multiple EGF-like domains protein 7, Vascular endothelial statin, NOTCH4-like protein ... | |||
TMPY-03780 | EGFL6 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
EGFL6, also known as EGF-L6, belongs to the epidermal growth factor (EGF) repeat superfamily. Members of this superfamily are characterized by the presence of EGF-like repeats and are often involved in the regulation of ... | |||
TMPY-00078 | EGFL6 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
EGFL6, also known as EGF-L6, belongs to the epidermal growth factor (EGF) repeat superfamily. Members of this superfamily are characterized by the presence of EGF-like repeats and are often involved in the regulation of ... | |||
TMPY-00094 | EGFL6 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
EGFL6, also known as EGF-L6, belongs to the epidermal growth factor (EGF) repeat superfamily. Members of this superfamily are characterized by the presence of EGF-like repeats and are often involved in the regulation of ... | |||
TMPH-00075 | At1g09870/F21M12_26 Protein, Arabidopsis thaliana, Recombinant (E. coli, His) | Arabidopsis thaliana | E. coli |
TMPY-04339 | EGFL7 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Epidermal growth factor-like protein 7, also known as EGF-like protein 7, Multiple epidermal growth factor-like domains protein 7, Multiple EGF-like domains protein 7, Vascular endothelial statin, NOTCH4-like protein ... | |||
TMPH-00076 | At1g09870/F21M12_26 Protein, Arabidopsis thaliana, Recombinant (Baculovirus, His) | Arabidopsis thaliana | Baculovirus |
TMPH-01168 | CDKN2B Protein, Human, Recombinant (His & Myc) | Human | E. coli |
CDKN2B Protein, Human, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPJ-01390 | MINPP1 Protein, Human, Recombinant (His) | Human | Human Cells |
Multiple Inositol Polyphosphate Phosphatase 1/MINPP1 is an enzyme that removes 3-phosphate from inositol phosphate substrates. MINPP1 also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate. MINPP1 is synth... | |||
TMPK-01151 | MXRA8 Protein, Human, Recombinant (His) | Human | HEK293 |
Mxra8 is a recently described receptor for multiple alphaviruses, including Chikungunya (CHIKV), Mayaro (MAYV), Ross River (RRV), and O'nyong nyong (ONNV) viruses. | |||
TMPY-04333 | LRRC15 Protein, Human, Recombinant (hFc) | Human | HEK293 |
LRRC15 (Leucine-Rich Repeat Containing 15) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. The tumor antigen 15-leucine-rich repeat-containing membrane protein (LRRC15) is a transmemb... | |||
TMPY-01601 | AXL Protein, Human, Recombinant (His) | Human | HEK293 |
Axl receptor tyrosine kinase, together with Tyro3 and Mer, constitute the TAM family of receptor tyrosine kinases. In the nervous system, Axl and its ligand Growth-arrest-specific protein 6 (Gas6) are expressed on multip... | |||
TMPK-00347 | Serum Albumin Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
Human serum albumin (HSA), the most prominent protein in plasma, binds different classes of ligands at multiple sites. HSA provides a depot for many compounds, affects pharmacokinetics of many drugs, holds some ligands i... | |||
TMPY-02900 | IL-17A Protein, Mouse, Recombinant | Mouse | E. coli |
IL17, also known as IL17a, is a cytokine that belongs to the IL-17 family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions i... | |||
TMPY-02886 | IL-17A Protein, Human, Recombinant | Human | E. coli |
IL17, also known as IL17a, is a cytokine that belongs to the IL-17 family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions i... | |||
TMPY-02424 | Prolactin Protein, Mouse, Recombinant (His) | Mouse | Baculovirus-Insect Cells |
Prolactin (PRL) is a hormone with multiple actions in the central nervous system (CNS) spanning from physiology to pathology. PRL exerts different actions through its receptors that can be found in both neurons and glial... | |||
TMPY-01815 | FOLR1 Protein, Human, Recombinant (His) | Human | HEK293 |
The protein encoded by FOLR1 gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product i... | |||
TMPY-06022 | FOLR1 Protein, Cynomolgus, Rhesus, Recombinant (His) | Cynomolgus,Rhesus | HEK293 |
The protein encoded by FOLR1 gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product i... | |||
TMPJ-01405 | Kallikrein 5/KLK5 Protein, Human, Recombinant (His) | Human | Human Cells |
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other di... | |||
TMPY-04778 | Prolactin Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Prolactin (PRL) is a hormone with multiple actions in the central nervous system (CNS) spanning from physiology to pathology. PRL exerts different actions through its receptors that can be found in both neurons and glial... | |||
TMPY-01803 | FOLR1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
The protein encoded by FOLR1 gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product i... | |||
TMPY-03284 | IL-T4 Protein, Human, Recombinant (His) | Human | HEK293 |
ILT4, also known as LILRB2, is a member of the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosin... | |||
TMPY-05592 | ULBP-2 Protein, Human, Recombinant(aa 1-217, His&AVI),Biotinylated | Human | HEK293 |
NKG2D ligand 2, also known as N2DL-2, NKG2DL2, ALCAN-alpha, Retinoic acid early transcript 1H, UL16-binding protein 2, ULBP2 and N2DL2, is cell membrane protein that belongs to the MHC class I family. ULBP2 / N2DL-2 is e... | |||
TMPY-03467 | IFN-beta Protein, Mouse, Recombinant | Mouse | HEK293 |
Interferons (IFNs) are natural glycoproteins belonging to the cytokine superfamily and are produced by the cells of the immune system of most vertebrates in response to challenges by foreign agents such as viruses, paras... | |||
TMPJ-00059 | IL-7 Protein, Human, Recombinant (His) | Human | Human Cells |
Human Interleukin 7 (IL-7) is a potent lymphoid cell growth factor stimulating the proliferation of lymphoid progenitors. IL7 can associate with the hepatocyte growth factor (HGF) to form a hybrid cytokine that functions... | |||
TMPY-01009 | TGFBI Protein, Human, Recombinant (His) | Human | HEK293 |
TGFBI is an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several ... | |||
TMPY-00756 | FGF-1 Protein, Human, Recombinant | Human | E. coli |
aFGF, also known as FGF1 and HBGF-1, is a member of the fibroblast growth factor family. The biological activity of aFGF protein is exerted through binding to four high affinity cell surface receptors (FGFR1–4), which re... | |||
TMPY-02333 | ULBP-2 Protein, Human, Recombinant (His) | Human | HEK293 |
NKG2D ligand 2, also known as N2DL-2, NKG2DL2, ALCAN-alpha, Retinoic acid early transcript 1H, UL16-binding protein 2, ULBP2 and N2DL2, is cell membrane protein that belongs to the MHC class I family. ULBP2 / N2DL-2 is e... | |||
TMPY-01906 | SEMA4D Protein, Human, Recombinant (His) | Human | HEK293 |
Semaphorin 4D (SEMA4D or CD100) is a member of the semaphorin family of proteins and an important mediator of the movement and differentiation of multiple cell types, including those of the immune, vascular, and nervous ... | |||
TMPY-03145 | IFN-beta Protein, Human, Recombinant | Human | CHO |
Interferons (IFNs) are natural glycoproteins belonging to the cytokine superfamily and are produced by the cells of the immune system of most vertebrates in response to challenges by foreign agents such as viruses, paras... | |||
TMPY-00831 | IFN-beta Protein, Human, Recombinant (hFc) | Human | HEK293 |
Interferons (IFNs) are natural glycoproteins belonging to the cytokine superfamily and are produced by the cells of the immune system of most vertebrates in response to challenges by foreign agents such as viruses, paras... | |||
TMPY-02929 | ENTPD2 Protein, Human, Recombinant (aa 29-460, His) | Human | Baculovirus-Insect Cells |
NTPDase 2, also known as ENTPD2, belongs to the ecto-nucleoside triphosphate diphosphohydrolase family (E-NTPDase). Members of E-NTPDase family are nucleotidases able to hydrolyze 5′-nucleoside tri- and/or diphosphates; ... | |||
TMPY-05842 | IL-11 Protein, Cynomolgus, Recombinant | Cynomolgus | E. coli |
IL11 is a multifunctional cytokine first isolated in 199 from bone marrow-derived stromal cells. It is a key regulator of multiple events in hematopoiesis, most notably the stimulation of megakaryocyte maturation. IL11 i... | |||
TMPY-00586 | CLEC-2 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
CLEC1B, also known as CLEC2, is a C-type lectin-like receptor expressed in myeloid cells and NK cells. Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 and NKG2D, ... | |||
TMPY-04832 | OX40L/TNFSF4 Protein, Human, Recombinant (hFc) | Human | HEK293 |
OX-40L, also known as TNFSF4 and CD252, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. OX-40L is an important costimulatory molecule that plays a crucial role in the regulation of T-cell-med... | |||
TMPY-05081 | Notch 1 Protein, Human, Recombinant (hFc) | Human | HEK293 |
NOTCH1 is one of the four mammalian Notch receptors, which is involved in the Notch signaling pathway. Specifically, NOTCH1 promotes the proliferation of myogenic precursor cells, and the NICD domain of NOTCH1 can impair... | |||
TMPY-01621 | TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His) | Human | HEK293 |
Hepatitis A virus cellular receptor 2 (HAVCR2), formerly known as T cell immunoglobulin and mucin domain-3 (TIM-3), is a transmembrane glycoprotein expressed on the surface of terminally differentiated Th1 cells but not ... | |||
TMPY-05227 | TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 |
Hepatitis A virus cellular receptor 2 (HAVCR2), formerly known as T cell immunoglobulin and mucin domain-3 (TIM-3), is a transmembrane glycoprotein expressed on the surface of terminally differentiated Th1 cells but not ... | |||
TMPY-03488 | IL-11 Protein, Human, Recombinant | Human | E. coli |
IL11 is a multifunctional cytokine first isolated in 199 from bone marrow-derived stromal cells. It is a key regulator of multiple events in hematopoiesis, most notably the stimulation of megakaryocyte maturation. IL11 i... | |||
TMPY-04178 | IL-11 Protein, Mouse, Recombinant | Mouse | E. coli |
IL11 is a multifunctional cytokine first isolated in 199 from bone marrow-derived stromal cells. It is a key regulator of multiple events in hematopoiesis, most notably the stimulation of megakaryocyte maturation. IL11 i... | |||
TMPY-01209 | IL-7R alpha/CD127 Protein, Human, Recombinant (His) | Human | HEK293 |
Interleukin 7 Receptor alpha (IL-7RA), also known as CD127, is a 75 kDa hematopoietic receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7 receptor alp... | |||
TMPY-00635 | IL-7R alpha/CD127 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Interleukin 7 Receptor alpha (IL-7RA), also known as CD127, is a 75 kDa hematopoietic receptor superfamily member that plays an important role in lymphocyte differentiation, proliferation, and survival. IL-7 receptor alp... | |||
TMPY-02286 | Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Matrix protein 1/M1 Protein (His) | H1N1 | E. coli |
The Influenza virus matrix protein 1 (M1) is a matrix protein of the influenza virus. M1 protein has been shown to play a crucial role in virus replication, assembly, and budding. It forms a coat inside the viral envelop... | |||
TMPY-02881 | RAGE Protein, Human, Recombinant | Human | HEK293 |
Receptor for Advanced Glycosylation End Products (RAGE, or AGER) is a member of the immunoglobulin super-family transmembrane proteins, as a signal transduction receptor which binds advanced glycation endproducts, certai... | |||
TMPY-02927 | RAGE Protein, Human, Recombinant (His) | Human | HEK293 |
Receptor for Advanced Glycosylation End Products (RAGE, or AGER) is a member of the immunoglobulin super-family transmembrane proteins, as a signal transduction receptor which binds advanced glycation endproducts, certai... | |||
TMPY-03531 | PSGL-1/CD162 Protein, Human, Recombinant (His) | Human | HEK293 |
P-selectin glycoprotein ligand-1 (PSGL-1), also known as SELPLG or CD162, is the high affinity ounter-receptor for P-selectin on expressed on activated endothelial cells and platelets. PSGL-1 is a mucin-type glycoprotein... | |||
TMPY-05013 | PSGL-1/CD162 Protein, Human, Recombinant (mFc) | Human | HEK293 |
P-selectin glycoprotein ligand-1 (PSGL-1), also known as SELPLG or CD162, is the high affinity ounter-receptor for P-selectin on expressed on activated endothelial cells and platelets. PSGL-1 is a mucin-type glycoprotein... | |||
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Cat No. | Product Name | ||
---|---|---|---|
L9700 | Endoplasmic Reticulum Stress Compound Library | 193 compounds | |
A unique collection of 193 endoplasmic reticulum stress (ER stress) related compounds used for high throughput screening (HTS) and high content screening (HCS); | |||
L3900 | DNA Damage & Repair Compound Library | 937 compounds | |
A unique collection of 937 DNA Damage & Repair related compounds for high throughput screening (HTS) and high content screening (HCS); | |||
L2195 | Anti-Prostate Cancer Compound Library | 2096 compounds | |
2096 compounds associated with prostate cancer that can be used for high-throughput and high-content screening. | |||
L3980 | DNA Damage and Repair Compound Library Plus | 667 compounds | |
Well-chosen 667 compounds with unique structures targeting DNA damage & repair; | |||
L6730 | Anti-virus Traditional Chinese Medicine Monomer Library | 270 compounds | |
A collection of 270 TCM monomers with anti-virus activity. An effective tool for drug development and pharmacological studies. | |||
L8700 | Ferroptosis Compound Library | 800 compounds | |
A unique collection of 800 ferroptosis signaling pathway related compounds, a powerful tool for new target identification, drug discovery, and mechanism study; | |||
L8110 | Reprogramming Compound Library | 1840 compounds | |
A unique collection of 1840 reprogramming signaling pathway-related bioactive small molecule compounds for high-throughput, high-content screening. | |||
L8200 | Anti-Aging Compound Library | 3324 compounds | |
A unique collection of 3324 anti-aging compounds for high throughput screening (HTS) and high content screening (HCS); | |||
L6750 | PBCRBS Traditional Chinese Medicine Compound Library | 588 compounds | |
A unique collection of 588 compounds derived from traditional Chinese medicines (TCMs) for promoting blood circulation and removing blood stasis. | |||
L6610 | Anti-infective Natural Product Library | 1070 compounds | |
A unique collection of 1070 species of natural products with anti-infective activity for high throughput screening (HTS) and high content screening (HCS); | |||
L7900 | Osteogenesis Compound Library | 320 compounds | |
A unique collection of 320 osteogenesis related compounds for high throughput and high content screening; | |||
L9000 | Apoptosis Compound Library | 1796 compounds | |
A unique collection of 1796 apoptosis-related compounds for apoptosis research, research in tumorigenesis, and anti-cancer drug screening; | |||
L1100 | Protease Inhibitor Library | 344 compounds | |
A unique collection of 344 protease and proteasome inhibitors for research in chemical genomics, and drug screening; | |||
L5700 | Featured Fragment Library | 246 compounds | |
A unique collection of 246 fragment-like small molecules for FBDD; | |||
L6120 | Flavonoid Natural Product Library | 477 compounds | |
A unique collection of 477 flavonoids can be used for high throughput and high content screening; | |||
L7600 | Chemokine Inhibitor Library | 59 compounds | |
A unique collection of 59 chemokines or chemokine receptors targeted compounds for high throughput and high content screening; | |||
L6720 | Anti-COVID-19 Traditional Chinese Medicine Compound Library | 1162 compounds | |
A unique collection of 1162 monomers from 60 TCM plants, a powerful tool for anti-COVID-19 drug discovery, can be used for HTS and HCS screening; | |||
L1710 | Anti-COVID-19 Compound Library | 1160 compounds | |
A unique collection of 1160 compounds with confirmed anti-SARS-CoV-2 activity or potential activity and part of them are broad-spectrum antiviral agents; | |||
L6740 | Anti-Colorectal Cancer Traditional Chinese Medicine Compound Library | 386 compounds | |
A collection of 386 TCM monomers with anti-colorectal activity. An effective tool for drug development and pharmacological studies. |