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J-147 is an experimental drug with reported effects against both Alzheimer's disease and ageing in mouse models of accelerated aging. It is a curcumin derivative and a potent neurogenic and neuroprotective drug candidate initially developed for the treatment of neurodegenerative conditions associated with aging that impacts many pathways implicated in the pathogenesis of diabetic neuropathy.

Anion transporter-4 (Compound 6) is a small molecule anion transporter protein that induces microtubule degradation and disrupts mitochondrial function. It elevates intracellular anion levels, such as chloride ions, by altering microtubule dynamics, promoting lipid peroxidation, and impairing mitochondrial function. Anion transporter-4 exerts anticancer effects by triggering ferroptosis and holds potential for cancer research.