oxa

Potent and selective peptide orexin OX1 receptor agonist (EC50 values are 8.29 and 187 nM for OX1 and OX2 receptors respectively). Truncated form of orexin A.

OXA (17-33) acetate is a more potent agonist of orexin-1 receptor (OX1, EC50 = 8.29 nM)) over OX2 (EC50 = 187 nM).

(6S,9S,12S)-Benzyl 12-benzyl-9-isobutyl-2,2-dimethyl-4,7,10-trioxo-6-phenethyl-3-oxa-5,8,11-triazatridecan-13-oate is a useful organic compound for research related to life sciences. The catalog number is T66648 and the CAS number is 868540-15-2.

OXA(17-33) TFA is a potent and selective agonist for the orexin-1 receptor (OX1), with approximately 23-fold higher affinity for OX1 (EC50 = 8.29 nM) compared to the orexin-2 receptor (OX2) (187 nM) [1].

WAY-181187 (SAX-187) oxalate is a selective and potent agonist of the 5-HT6 receptor (Ki: 2.2 nM; EC50: 6.6 nM) that mediates 5-HT6 receptor-dependent signaling pathways, including cAMP, Fyn, and ERK1 2 kinases.

(S)-2-((S)-2-Cyclohexyl-2-(pyrazine-2-carboxamido)acetamido)-3,3-dimethylbutanoic acid, catalog number T66357 and CAS number 402958-96-7, is a valuable organic compound utilized in life sciences research.

(S)-Benzyl (4-(2,5-dioxooxazolidin-4-yl)butyl)carbamate is a useful organic compound for research related to life sciences. The catalog number is T66458 and the CAS number is 1676-86-4.

(S)-Pyrrolidine-2-carboxamide hydrochloride, catalog number T67652 and CAS number 42429-27-6, is a valuable organic compound for life sciences research.

NoxA1ds TFA is a potent and selective inhibitor of NADPH oxidase 1 (NOX1) with an inhibition concentration (IC50) of 20 nM, showing selectivity over NOX2, NOX4, NOX5, and xanthine oxidase. It effectively inhibits NOX1-derived O2- production in HT-29 human colon cancer cells and attenuates VEGF-induced migration of human pulmonary artery endothelial cells under hypoxic conditions in vitro.

NoxaBH3, a cysteine-based cross-linked peptide, exhibits enhanced cell permeability and greater inhibitory efficacy against Mcl-1. It binds to the endogenous CXCR4 ligand, resulting in the formation of a ubiquitin-NoxaBH3 conjugate that is subsequently delivered to cancer cells [1].

Noxa A BH3, a bioactive peptide, encompasses the BH3 domain of the Noxa protein.

r8-Gly-Noxa A BH3 is a biologically active, cell-permeable peptide comprising amino acid residues 17 to 36 from the BH3 (death) domain of Noxa A, modified by eight D-Arginine residues and a Glycine linker at its amino terminus.

Noxa B BH3, a biologically active peptide encompassing the BH3 domain of the Noxa protein, displays targeted biological activity.

L-Glutamic γ-monohydroxamate is an antitumor compound that impedes cell proliferation, selectively hinders L-histidine uptake in microvascular endothelial cells, and serves as a vanadium ligand, enhancing glucose uptake and metabolism, resulting in reduced blood glucose levels in vivo [1] [2] [3].

Siltartoxatug is a humanized IgG1κ monoclonal antibody specifically targeting tetanus toxin (tetanus toxin), with Human IgG1 kappa, Isotype Control serving as its corresponding isotype control.

Potent and selective NADPH oxidase 1 (NOX1) inhibitor (IC50 = 20 nM). Exhibits selectivity for NOX1 over NOX2, NOX4, NOX5 and xanthine oxidase. Inhibits NOX1-derived O2- production in HT-29 human colon cancer cells. Attenuates VEGF-induced human pulmonary

NoxA1ds acetate is a potent and selective NADPH oxidase 1 (NOX1) inhibitor (IC50 : 20 nM). Exhibits selectivity for NOX1 over NOX2, NOX4, NOX5 and xanthine oxidase. Inhibits NOX1-derived O2- production in HT-29 human colon cancer cells. Attenuates VEGF-induced human pulmonary artery endothelial cell migration under hypoxic conditions in vitro.