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Helioxanthin derivative 5-4-2

Name: Helioxanthin derivative 5-4-2
Brand: TargetMol
SKU: T11550
Price: 197 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T11550Cas No. 203935-39-1

Alias Helioxanthin 5-4-2

Helioxanthin derivative 5-4-2 (Helioxanthin 5-4-2) is an analogue of helioxanthin that shows anti-HBV activity in vitro and can be used to study HBV.

Helioxanthin derivative 5-4-2

🥰Excellent

Purity: 99.92%

Catalog No. T11550Alias Helioxanthin 5-4-2Cas No. 203935-39-1

Helioxanthin derivative 5-4-2 (Helioxanthin 5-4-2) is an analogue of helioxanthin that shows anti-HBV activity in vitro and can be used to study HBV.

Pack Size	Price	Availability
1 mg	$197	In Stock
5 mg	$596	In Stock
10 mg	$847	In Stock
25 mg	$1,250	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.92%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Helioxanthin derivative 5-4-2 (Helioxanthin 5-4-2) is an analogue of helioxanthin that shows anti-HBV activity in vitro and can be used to study HBV.
Targets&IC50	HBV:0.08 μM
In vitro	Helioxanthin and Helioxanthin derivative 5-4-2, which had potent anti-HBV activities in HepG2.2.15 cells, with the EC50s of 1 and 0.08 microM, respectively[2].
Synonyms	Helioxanthin 5-4-2

Chemical Properties

Molecular Weight	347.32
Formula	C₂₀H₁₃NO₅
Cas No.	203935-39-1
Smiles	O=C1NCc2c1cc1ccc3OCOc3c1c2-c1ccc2OCOc2c1
Relative Density.	1.491 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 30 mg/mL (86.38 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (5.76 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.8792 mL	14.3959 mL	28.7919 mL	143.9595 mL
5 mM	0.5758 mL	2.8792 mL	5.7584 mL	28.7919 mL
10 mM	0.2879 mL	1.4396 mL	2.8792 mL	14.3959 mL
20 mM	0.1440 mL	0.7198 mL	1.4396 mL	7.1980 mL
50 mM	0.0576 mL	0.2879 mL	0.5758 mL	2.8792 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc