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Cat No. Product Name Synonyms Targets
T9372 D-Histidine Mitochondrial Metabolism
D-Histidine is an enantiomer of L-histidine. L-Histidine is an inhibitor of mitochondrial glutamine transport and also an essential amino acid for infants.
TN1586 Dihydrorotenone Apoptosis , Mitochondrial Metabolism
Dihydrorotenone is a potent mitochondrial inhibitor and probably induces Parkinsonian syndrome.
T10857 Coenzyme A Endogenous Metabolite
Coenzyme A is an obligatory cofactor in all living cells synthesized from pantothenate (Vitamin B5), adenosine triphosphate (ATP), and cysteine.
T15373 Gboxin ATPase , Mitochondrial Metabolism
Gboxin is an inhibitor of oxidative phosphorylation that targets glioblastoma,inhibits the activity of F0F1 ATP synthase, with antitumour activity.
T9777 THP104c Mitochondrial Metabolism
THP104c is an inhibitor of mitochondrial fission.
T12408 Perhexiline maleate Others , Mitochondrial Metabolism
Perhexiline maleate is an orally active inhibitor of CPT1 and CPT2 that reduces fatty acid metabolism. The IC50 values of perhexiline maleate against rat heart and liver CPT 1 were 77 and 148 μM, respectively.
T8433 HQNO Mitochondrial Metabolism
HQNO is a natural product isolated from P. aeruginosa,and is a potent inhibitor of electron transport chain(Kd of 64 nM for complex III). It also is a potent mitochondrial NDH-2 inhibitorin many species.
T14497 BAM 15 OXPHOS , Mitochondrial Metabolism
BAM 15 is an uncoupler of mitochondrial protonophore.
T15241 ER-000444793 Others , Mitochondrial Metabolism
ER-000444793 is a potent mitochondrial permeability transition pore (mPTP) opening inhibitor and it also inhibits mPTP (IC50: 2.8 μM).
T10706 CCI-006 Mitochondrial Metabolism
CCI-006, a selective inhibitor and chemosensitizer for MLL-rearranged leukemia cells, disrupts mitochondrial respiration. This action leads to irreversible mitochondrial depolarization and triggers a pro-apoptotic unfold...
T19428 Mito-TEMPO Reactive Oxygen Species , Mitochondrial Metabolism
Mito-TEMPO is a mitochondria-targeted superoxide dismutase mimetic. Mito-TEMPO scavenges superoxide and alkyl radicals and prevents mitochondrial oxidation, necrosis and apoptosis.
T9169 MPP+ iodide Mitochondrial Metabolism , Autophagy
MPP+ iodide, the metabolite of a neurotoxin MPTP, causes symptom of Parkinson's disease (PD) in animal models by selectively destroying dopaminergic neurons in substantia nigra. MPP+ induces dopamine transporter (DAT) ex...
TN6772 Malabaricone C Others
Malabaricone C is a bioactive chemical.
T1768 7ACC2 Mitochondrial Metabolism , Monocarboxylate transporter
7ACC2 is a new potent MCT inhibitor with IC50 of 11 nM for [14C]-lactate influx; new antitumor treatment targeting lactate transport in Y cells.
T8734 Choline Others
Choline is a ubiquitous water soluble nutrient, often associated with the B vitamins
T4639 Azemiglitazone MSDC 0602 Mitochondrial Metabolism , mTOR
Azemiglitazone (MSDC 0602) is an insulin sensitizer potentially for the treatment of diabetes.
T14140 Agaric acid Agaricinic Acid Mitochondrial Metabolism , AChR
Agaricic acid is an adenine nucleotide translocase antagonist.It is obtained from various plants of the fungous tribe, i.e. Polyporus officinalis and Polyporus igniarius. Agaric acid (Agaricinic Acid) induces mitochondri...
T9031 MCU-i4 Others , Mitochondrial Metabolism
MCU-i4 is a novel negative modulator of the MCU, binding MICU1 and impairing muscle cell growth.
T8091 Trans-4-Hydroxycyclohexanecarboxylic Acid Others
trans-4-Hydroxycyclohexanecarboxylic Acid is an organic intermediate.
T7922 Kresoxim-Methyl Others , Mitochondrial Metabolism , Antifungal
Kresoxim-methyl is a strobilurin fungicide,inhibits conidial germination of V. inaequalis isolates from apple orchards .
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