mas

Amphiphilic peptide Mas7, a structural analogue of mastoparan is a known activator of heterotrimeric Gi-proteins and its downstream effectors.

Mas7 acetate(145854-59-7 free base) (Mastoparan 7 acetate) , a structural analogue of mastoparan is a known activator of heterotrimeric Gi-proteins and its downstream effectors.

Dermaseptin acetate, a peptide isolated from frog skin, exhibits potent antimicrobial activity against bacteria, fungi, and protozoa at micromolar concentration[1].

Mastoparan X, a tetradecapeptide derived from wasp venom, functions as a GTP-binding regulatory protein (G protein)-activating peptide. It directly activates G proteins coupled to phospholipase C, inducing secretion in various cell types [1].

Polistes mastoparan, an antimicrobial peptide, enhances K+ efflux in S. aureus cells and reduces cell viability, exhibiting an EC50 of 5 μM [1].

Dermaseptin-B3 is an antimicrobial peptide that exhibits inhibitory effects against both Gram-positive and Gram-negative bacterial strains, with minimum inhibitory concentrations (MICs) of 1.3, 2.3, 5.0, 2.6, and 2.3 μM for S. aureus, P. aeruginosa, E. (ATCC 25922), and E. (54127) respectively. Additionally, this compound demonstrates antiproliferative activity against tumor cells [1] [2].

Mastoparan B, an antimicrobial peptide originating from the hornet Vespa, induces morphological changes in red blood cells, transforming their typical discoid shape into a serrated configuration [1].

Semastatin-5B, an anti-angiogenic peptide composed of 17 amino acids, can be derived from proteins featuring type I thrombospondin motifs [1].

Dermaseptin-B9, an antimicrobial peptide, has been isolated from the Phyllomedusinae subfamily of frogs [1].

Dermaseptin-B5, an antimicrobial peptide sourced from the skin secretions of the South American frog Phyllomedusa bicolor, exhibits potent antimicrobial activity [1].

Dermaseptin-B4 is a potent antimicrobial peptide sourced from the skin secretions of the South American frog, Phyllomedusa bicolor [1].

Mastoparan is a peptide toxin from wasp venom. It has the chemical structure Ile-Asn-Leu-Lys-Ala-Leu-Ala-Ala-Leu-Ala-Lys-Lys-Ile-Leu-NH2.

Mastoparan acetate is a peptide toxin from wasp venom. It has the chemical structure Ile-Asn-Leu-Lys-Ala-Leu-Ala-Ala-Leu-Ala-Lys-Lys-Ile-Leu-NH2.

Peptide from giant hornet Vespa orientalis that has biological effects similar to mast cell degranulating peptide from bee venom.

Mast Cell Degranulating Peptide HR-2 acetate from giant hornet Vespa orientalis that has biological effects similar to mast cell degranulating peptide from bee venom.

Mast cell degranulating peptide (28-49) is a bee venom depolarizer that enhances cGMP levels in cerebellum tablets of mice.

Dermaseptin is a peptide expressed by the frog skin glands with a potent antimicrobial activity against bacteria, fungi and protozoa.

Jagged-1 (188-204) TFA(219127-21-6 free base) is a fragment of the JAG-1 protein. JAG-1 is Notch ligand, a peptide that is the most conspicuously expressed ligand in skin. JAG-1 induces epidermal maturation. Exposing submerged keratinocytes monolayers to JAG-1 with elevated calcium concentration produces stratification with loricrin expression and NF-alphaB activation.

Notch 1 TFA encodes a member of the NOTCH family of proteins.

Z-LLNle-CHO is a cell permeable inhibitor of gamma-secretase. Z-LLNle-CHO induces apoptosis of human glioblastoma tumor-initiating cells by proteasome inhibition and mitotic arrest response.

Z-Phe-Ala-diazomethylketone directly binds to Aβ42 monomers and small oligomers, inhibiting Aβ42 dodecamer formation and preventing Aβ42 fibrillogenesis in solution. This compound holds potential for research into neurodegenerative disorders [1].

Adenoregulin (Dermaseptin b2), an antimicrobial peptide antibiotic, exhibits efficacy against both Gram-negative and Gram-positive bacteria, as well as yeast and fungi. Additionally, it augments the affinity of agonists for the A1 adenosine receptor [1].

DAPM (gamma-Secretase Inhibitor XVI) is a Notch pathway inhibitor with anticancer activity and antiproliferative effects, inhibits cell proliferation and induces the expression of Krüppel-like Factor 4 (KLF4) and p21 in human colon cancer cells, inhibits Notch signaling, and can be used in the study of renal tubular adenomas.

CH 5450 (Z-Ile-Glu-Pro-Phe-Ome) is a short peptide inhibitor of chymase in the human heart.