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Anti-Pertuzumab Antibody (4G14) is a Mouse antibody targeting Pertuzumab. Anti-Pertuzumab Antibody (4G14) can be used in ELISA, Competitive ELISA.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 40 μg | $305 | 7-10 days | 7-10 days |
| Description | Anti-Pertuzumab Antibody (4G14) is a Mouse antibody targeting Pertuzumab. Anti-Pertuzumab Antibody (4G14) can be used in ELISA, Competitive ELISA. |
| Synonyms | Perjeta, 2C4 |
| Ig Type | IgG1,K |
| Clone | 4G14 |
| Specificity | Pertuzumab |
| Application | |
| Recommended Dose | ELISA: 0.01-0.1 µg/ml; Competitive ELISA: 2-20 µg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Purification | Protein A affinity column |
| Appearance | Lyophilized. Reconstitute the lyophilized powder with deionized water (or equivalent) to a final concentration of 0.5 mg/ml. |
| Formulation | Lyophilized with PBS, pH 7.2, containing 0.02% sodium azide. |
| Research Background | Pertuzumab (also called 2C4, trade name Perjeta) is a monoclonal antibody used in combination with trastuzumab and docetaxel for the treatment of metastatic HER2-positive breast cancer; it also used in the same combination as a neoadjuvant in early HER2-positive breast cancer. The epitope for pertuzumab is the domain of HER2 where it binds to HER3, and pertuzumab prevents the HER2/HER3 dimer from forming, which blocks signalling by the dimer to prevent HER2 from functioning. |
| Conjucates | Unconjugated |
| Immunogen | Pertuzumab |
| Stability & Storage | The lyophilized product store at -20°C or -80°C for 12 months. The reconstituted antibody can be stored at 2°C-8°C for 2-3 weeks or at -20°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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