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Anti-Avelumab Antibody (1S157)
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Catalog No. TMAS-00012
Alias Bavencio
Anti-Avelumab Antibody (1S157) is a Mouse antibody targeting Avelumab. Anti-Avelumab Antibody (1S157) can be used in ELISA, Competitive ELISA.
Anti-Avelumab Antibody (1S157)
Anti-Avelumab Antibody (1S157)
😃Good
Catalog No. TMAS-00012Alias Bavencio
Anti-Avelumab Antibody (1S157) is a Mouse antibody targeting Avelumab. Anti-Avelumab Antibody (1S157) can be used in ELISA, Competitive ELISA.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 40 μg | $305 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Avelumab Antibody (1S157) is a Mouse antibody targeting Avelumab. Anti-Avelumab Antibody (1S157) can be used in ELISA, Competitive ELISA. |
| Synonyms | Bavencio |
| Ig Type | IgG1,κ |
| Clone | 1S157 |
| Specificity | Avelumab |
| Application | |
| Recommended Dose | ELISA: 0.001-0.1 µg/ml; Competitive ELISA: 10-50 µg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Purification | Protein A affinity column |
| Appearance | Lyophilized. Reconstitute the lyophilized powder with deionized water (or equivalent) to a final concentration of 0.5 mg/ml. |
| Formulation | Lyophilized with PBS, pH 7.2, containing 0.02% sodium azide. |
| Research Background | Avelumab with trade name Bavencio, is an FDA-approved drug to treat Merkel cell carcinoma, urothelial carcinoma, and renal cell carcinoma. Avelumab is a whole monoclonal antibody of isotype IgG1 that binds to the programmed death-ligand 1 (PD-L1) and therefore inhibits binding to its receptor programmed cell death 1 (PD-1). PD-L1 can be highly expressed on certain tumors, which is thought to lead to reduced activation of immune cells (cytotoxic T-cells in particular) that might otherwise recognize and attack the cancer. Inhibition of PD-L1 by Avelumab can remove this inhibitor effect and thereby engender an anti-tumor response. It is one of several ways to block inhibitory signals related to T-cell activation, a more general strategy known as "immune checkpoint inhibition." |
| Conjucates | Unconjugated |
| Immunogen | Avelumab |
Stability & Storage
| Stability & Storage | The lyophilized product store at -20°C or -80°C for 12 months. The reconstituted antibody can be stored at 2°C-8°C for 2-3 weeks or at -20°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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