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Anti-Nivolumab Antibody (8J455)

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Catalog No. TMAS-00057
Alias Opdivo

Anti-Nivolumab Antibody (8J455) is a Mouse antibody targeting Nivolumab. Anti-Nivolumab Antibody (8J455) can be used in ELISA.

Anti-Nivolumab Antibody (8J455)

Anti-Nivolumab Antibody (8J455)

😃Good
Catalog No. TMAS-00057Alias Opdivo
Anti-Nivolumab Antibody (8J455) is a Mouse antibody targeting Nivolumab. Anti-Nivolumab Antibody (8J455) can be used in ELISA.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
40 μg$3057-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Nivolumab Antibody (8J455) is a Mouse antibody targeting Nivolumab. Anti-Nivolumab Antibody (8J455) can be used in ELISA.
SynonymsOpdivo
Ig Type
IgG1
Clone
8J455
Specificity
The product is specific for Nivolumab. The antibody is recommended as a capture antibody in a pharmacokinetic (PK) bridging assay with detection antibody Anti-Nivolumab Antibody-Biotin (3N979) (TMAS-00056B).
Application
Recommended Dose
ELISA: 0.01-0.1 µg/ml
Antibody Type
Monoclonal
Host SpeciesMouse
PurificationProtein A affinity column
AppearanceLyophilized. Reconstitute the lyophilized powder with deionized water (or equivalent) to a final concentration of 0.5 mg/mL.
FormulationLyophilized with PBS, pH 7.4, containing 0.02% sodium azide.
Research BackgroundNivolumab (Opdivo) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of patients with unresectable or metastatic melanoma. Nivolumab binds to the human cell surface receptor PD-1 (Programmed Cell Death Protein 1) and blocks its interaction with PD-L1, resulting in the activation of T-cell-mediated immune responses against tumor cells.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Nivolumab
Chemical Properties
Stability & Storage
Stability & StorageThe lyophilized product store at -20°C or -80°C for 12 months. The reconstituted antibody can be stored at 2°C-8°C for 2-3 weeks or at -20°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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