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Anti-Nivolumab Antibody (8J455) is a Mouse antibody targeting Nivolumab. Anti-Nivolumab Antibody (8J455) can be used in ELISA.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 40 μg | $305 | 7-10 days | 7-10 days |
| Description | Anti-Nivolumab Antibody (8J455) is a Mouse antibody targeting Nivolumab. Anti-Nivolumab Antibody (8J455) can be used in ELISA. |
| Synonyms | Opdivo |
| Ig Type | IgG1 |
| Clone | 8J455 |
| Specificity | The product is specific for Nivolumab. The antibody is recommended as a capture antibody in a pharmacokinetic (PK) bridging assay with detection antibody Anti-Nivolumab Antibody-Biotin (3N979) (TMAS-00056B). |
| Application | |
| Recommended Dose | ELISA: 0.01-0.1 µg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Purification | Protein A affinity column |
| Appearance | Lyophilized. Reconstitute the lyophilized powder with deionized water (or equivalent) to a final concentration of 0.5 mg/mL. |
| Formulation | Lyophilized with PBS, pH 7.4, containing 0.02% sodium azide. |
| Research Background | Nivolumab (Opdivo) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of patients with unresectable or metastatic melanoma. Nivolumab binds to the human cell surface receptor PD-1 (Programmed Cell Death Protein 1) and blocks its interaction with PD-L1, resulting in the activation of T-cell-mediated immune responses against tumor cells. |
| Conjucates | Unconjugated |
| Immunogen | Nivolumab |
| Stability & Storage | The lyophilized product store at -20°C or -80°C for 12 months. The reconstituted antibody can be stored at 2°C-8°C for 2-3 weeks or at -20°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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