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Anti-Repulsive guidance molecule A Antibody (3L87)

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Catalog No. TMAS-00443
Alias RGMA, RGM domain family member A, RGM, Repulsive guidance molecule A

Anti-Repulsive guidance molecule A Antibody (3L87) is a Rabbit antibody targeting Repulsive guidance molecule A. Anti-Repulsive guidance molecule A Antibody (3L87) can be used in ICC/IF, WB.

Anti-Repulsive guidance molecule A Antibody (3L87)

Anti-Repulsive guidance molecule A Antibody (3L87)

😃Good
Catalog No. TMAS-00443Alias RGMA, RGM domain family member A, RGM, Repulsive guidance molecule A
Anti-Repulsive guidance molecule A Antibody (3L87) is a Rabbit antibody targeting Repulsive guidance molecule A. Anti-Repulsive guidance molecule A Antibody (3L87) can be used in ICC/IF, WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$3697-10 days7-10 days
100 μL$6777-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Repulsive guidance molecule A Antibody (3L87) is a Rabbit antibody targeting Repulsive guidance molecule A. Anti-Repulsive guidance molecule A Antibody (3L87) can be used in ICC/IF, WB.
SynonymsRGMA, RGM domain family member A, RGM, Repulsive guidance molecule A
Ig Type
IgG
Clone
3L87
Reactivity
Human,Mouse,Rat
Specificity
Repulsive guidance molecule A
Verified Activity
Western blot analysis of RGMA expression in Hela cell lysate.
Application
Recommended Dose
ICC/IF: 1:50-1:200; WB: 1:1000-1:2000
Antibody Type
Monoclonal
Host SpeciesRabbit
PurificationAffinity-chromatography
AppearanceLiquid
FormulationSupplied in 10 mM phosphate buffered saline, pH 7.4, 150 mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Research BackgroundMember of the repulsive guidance molecule (RGM) family that performs several functions in the developing and adult nervous system. Regulates cephalic neural tube closure, inhibits neurite outgrowth and cortical neuron branching, and the formation of mature synapses. Binding to its receptor NEO1/neogenin induces activation of RHOA-ROCK1/Rho-kinase signaling pathway through UNC5B-ARHGEF12/LARG-PTK2/FAK1 cascade, leading to collapse of the neuronal growth cone and neurite outgrowth inhibition.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthesized peptide: human Repulsive guidance molecule A
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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