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Anti-Repulsive guidance molecule A Antibody (3L87) is a Rabbit antibody targeting Repulsive guidance molecule A. Anti-Repulsive guidance molecule A Antibody (3L87) can be used in ICC/IF, WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $369 | 7-10 days | 7-10 days | |
| 100 μL | $677 | 7-10 days | 7-10 days |
| Description | Anti-Repulsive guidance molecule A Antibody (3L87) is a Rabbit antibody targeting Repulsive guidance molecule A. Anti-Repulsive guidance molecule A Antibody (3L87) can be used in ICC/IF, WB. |
| Synonyms | RGMA, RGM domain family member A, RGM, Repulsive guidance molecule A |
| Ig Type | IgG |
| Clone | 3L87 |
| Reactivity | Human,Mouse,Rat |
| Specificity | Repulsive guidance molecule A |
| Verified Activity | Western blot analysis of RGMA expression in Hela cell lysate. |
| Application | |
| Recommended Dose | ICC/IF: 1:50-1:200; WB: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Supplied in 10 mM phosphate buffered saline, pH 7.4, 150 mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| Research Background | Member of the repulsive guidance molecule (RGM) family that performs several functions in the developing and adult nervous system. Regulates cephalic neural tube closure, inhibits neurite outgrowth and cortical neuron branching, and the formation of mature synapses. Binding to its receptor NEO1/neogenin induces activation of RHOA-ROCK1/Rho-kinase signaling pathway through UNC5B-ARHGEF12/LARG-PTK2/FAK1 cascade, leading to collapse of the neuronal growth cone and neurite outgrowth inhibition. |
| Conjucates | Unconjugated |
| Immunogen | A synthesized peptide: human Repulsive guidance molecule A |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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