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Anti-Obinutuzumab Antibody (8M836)
😃Good
Catalog No. TMAS-00062
Alias Gazyva
Anti-Obinutuzumab Antibody (8M836) is a Mouse antibody targeting Obinutuzumab. Anti-Obinutuzumab Antibody (8M836) can be used in ELISA.
Anti-Obinutuzumab Antibody (8M836)
Anti-Obinutuzumab Antibody (8M836)
😃Good
Catalog No. TMAS-00062Alias Gazyva
Anti-Obinutuzumab Antibody (8M836) is a Mouse antibody targeting Obinutuzumab. Anti-Obinutuzumab Antibody (8M836) can be used in ELISA.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 40 μg | $305 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Obinutuzumab Antibody (8M836) is a Mouse antibody targeting Obinutuzumab. Anti-Obinutuzumab Antibody (8M836) can be used in ELISA. |
| Synonyms | Gazyva |
| Ig Type | IgG1,κ |
| Clone | 8M836 |
| Specificity | The product is specific for Obinutuzumab. The antibody is recommended as a capture antibody in a pharmacokinetic (PK) bridging assay with detection antibody Anti-Obinutuzumab Antibody-Biotin (5T476) (TMAS-00061B). |
| Application | |
| Recommended Dose | ELISA: 0.005-1 µg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Purification | Protein A affinity column |
| Appearance | Lyophilized. Reconstitute the lyophilized powder with deionized water (or equivalent) to a final concentration of 0.5 mg/mL. |
| Formulation | Lyophilized with PBS, pH 7.4, containing 0.02% sodium azide. |
| Research Background | Obinutuzumab is a humanized anti-CD20 monoclonal antibody, originated by GlycArt Biotechnology AG and developed by Roche as a cancer treatment. It was approved under the trade name Gazyva by the US FDA in 2013, and as Gazyvaro by the EMA in Europe, for the treatment of chronic lymphocytic leukemia in combination with chemotherapy in treatment-naive patients, and as a second line treatment for follicular lymphoma. Obinutuzumab is a fully humanized monoclonal antibody that binds to an epitope on CD20 that partially overlaps with the epitope recognized by rituximab. Obinutuzumab binds to CD20 on B cells and causes these cells to be destroyed by engaging the adaptive immune system, directly activating intracellular apoptosis pathways, and activating the complement system. |
| Conjucates | Unconjugated |
| Immunogen | Obinutuzumab |
Stability & Storage
| Stability & Storage | The lyophilized product store at -20°C or -80°C for 12 months. The reconstituted antibody can be stored at 2°C-8°C for 2-3 weeks or at -20°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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