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Anti-KIT Monoclonal Antibody (5M199)
(Synonyms: SCFR, PBT, MASTC, C-Kit, CD117) Copy Product Info
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Synonyms: SCFR, PBT, MASTC, C-Kit, CD117
Catalog No. TMAT-0800 Copy Product Info
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Anti-KIT Monoclonal Antibody (5M199) is a Mouse antibody targeting KIT. Anti-KIT Monoclonal Antibody (5M199) can be used in IF,FCM.
Anti-KIT Monoclonal Antibody
(5M199)
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-KIT Monoclonal Antibody (5M199) is a Mouse antibody targeting KIT. Anti-KIT Monoclonal Antibody (5M199) can be used in IF,FCM. |
| Synonyms | SCFR, PBT, MASTC, C-Kit, CD117 |
| Ig Type | IgG2b |
| Clone | 5M199 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IF: 1/50-1/200; FCM: 1/200-1/400 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a receptor tyrosine kinase. This gene was initially identified as a homolog of the feline sarcoma viral oncogene v-kit and is often referred to as proto-oncogene c-Kit. The canonical form of this glycosylated transmembrane protein has an N-terminal extracellular region with five immunoglobulin-like domains, a transmembrane region, and an intracellular tyrosine kinase domain at the C-terminus. Upon activation by its cytokine ligand, stem cell factor (SCF), this protein phosphorylates multiple intracellular proteins that play a role in in the proliferation, differentiation, migration and apoptosis of many cell types and thereby plays an important role in hematopoiesis, stem cell maintenance, gametogenesis, melanogenesis, and in mast cell development, migration and function. This protein can be a membrane-bound or soluble protein. Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous leukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of human KIT (AA: 23-322) expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | KIT |
| Gene ID | |
| Protein Name | Mast/stem cell growth factor receptor Kit |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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