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Anti-FMC63 Antibody-iFluor 647 (5N304)
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Catalog No. TMAS-00042F647
Alias FMC63-scFv, FMC63-CD19, FMC63 scFv, FMC 63, Anti-CD19 (FMC63) CAR, Anti-CD19 (FMC63)
Anti-FMC63 Antibody-iFluor 647 (5N304) is a Rabbit antibody targeting FMC63. Anti-FMC63 Antibody-iFluor 647 (5N304) can be used in FCM.
Anti-FMC63 Antibody-iFluor 647 (5N304)
Anti-FMC63 Antibody-iFluor 647 (5N304)
😃Good
Catalog No. TMAS-00042F647Alias FMC63-scFv, FMC63-CD19, FMC63 scFv, FMC 63, Anti-CD19 (FMC63) CAR, Anti-CD19 (FMC63)
Anti-FMC63 Antibody-iFluor 647 (5N304) is a Rabbit antibody targeting FMC63. Anti-FMC63 Antibody-iFluor 647 (5N304) can be used in FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 T | $3,693 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Chemical Properties
| Description | Anti-FMC63 Antibody-iFluor 647 (5N304) is a Rabbit antibody targeting FMC63. Anti-FMC63 Antibody-iFluor 647 (5N304) can be used in FCM. |
| Synonyms | FMC63-scFv, FMC63-CD19, FMC63 scFv, FMC 63, Anti-CD19 (FMC63) CAR, Anti-CD19 (FMC63) |
| Ig Type | IgG, κ |
| Clone | 5N304 |
| Specificity | FMC63 scFv and CARs derived from FMC63 scFv |
| Application | |
| Recommended Dose | FCM: 1:50 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Purification | Protein A affinity column |
| Appearance | Liquid |
| Formulation | Supplied in PBS, pH 7.2, containing 10 mg/ml BSA, 0.03% ProClin300 and 50% glycerol. |
| Research Background | The FMC63 scFv (single-chain variable fragment) is a key component in many chimeric antigen receptor (CAR) designs, particularly in CAR-T cell therapies. Derived from a murine monoclonal antibody, FMC63 specifically targets human CD19, a cell surface protein highly expressed on B-cells, including malignant B-cells in B-cell leukemias and lymphomas. This scFv fragment is engineered by fusing the variable regions of the heavy and light chains of the antibody, preserving the antigen-binding capability while significantly reducing its size. This smaller, single-chain format enhances its integration into CAR constructs, enabling the recognition and destruction of CD19-positive cells by CAR-T cells. FMC63-based CARs are widely used in immunotherapy, particularly in FDA-approved treatments for B-cell malignancies, such as Kymriah® and Yescarta®. |
| Conjucates | iFluor 647 |
| Others Formats | Unconjugated |
| Antibody Types Available | 2 |
| Immunogen | FMC63 scFv |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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