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Search Results for " nos "

20

Compounds

Cat No. Product Name Synonyms Targets
T21700 NOS-IN-1  2-Imino-4-methylpiperidine (acetate) NOS
NOS-IN-1 (2-Imino-4-methylpiperidine acetate) is a potent and orally active inhibitor of NO synthase (NOS) isoforms. NOS-IN-1 exhibits IC50s of 0.1 μM, 0.2 μM, and 1.1μM for human iNOS (hiNOS), hnNOS and heNOS, respectiv...
T14286 ANB-NOS Others
ANB-NOS is a alkyl/ether-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system w...
T73353 NOS-IN-3
NOS-IN-3 is a potent, selective, imidamide derived NOS inhibitor with an IC 50 against iNOS of 4.6 µM, without inhibiting eNOS . NOS-IN-3 has little toxicity and can be studied in the treatment of inducible isoform invo...
T61426 NOS-IN-2
NOS-IN-2 (Compound 4i), an imidamide-derived NOS inhibitor, exhibits high potency and selectivity, specifically inhibiting iNOS with an IC50 of 20 μM while sparing eNOS. Demonstrating minimal toxicity, it is suitable for...
T6S2023 Harpagoside Others , COX , NO Synthase
1. Harpagoside has anti-inflammatory activity. 2. Harpagoside at 3 mM concentration, shows moderate inhibition of seed germination. 3. Harpagoside can inhibit lipopolysaccharide-induced mRNA levels and protein expression...
TQ0301 Kuwanon A NO Synthase
Kuwanon A inhibits nitric oxide production (IC50: 10.5 μM). Kuwanon A is a flavone derivative isolated from Morus alba L.
T2S0765 Epibetulinic acid NO Synthase , Prostaglandin Receptor
Epibetulinic acid has anti-inflammatory activity, it exhibits potent inhibitory effects on NO and prostaglandin E(2) production in mouse macrophages (RAW 264.7) stimulated with bacterial endotoxin.
T6S1665 Irisflorentin Others , NO Synthase
1. Irisflorentin blocks apoptosis pathways, by exerting its effects by promoting rpn-3 expression to enhance the activity of proteasomes and down-regulating egl-1 expression. 2. Irisflorentin has anti-inflammatory mechan...
T7682 Asymmetric dimethylarginine Endogenous Metabolite , NO Synthase , NOD
Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS)
T7474 7-Nitroindazole NOS
7-Nitroindazole is a non-selective inhibitor of NOS isoforms in vitro for neuronal nitric oxide synthase showing a 10-fold selectivity for neuronal NOS.
T10107 3-Bromo-7-nitroindazole NOS
3-Bromo-7-nitroindazole is a more potent and selective inhibitor of neuronal nitric oxide synthase (nNOS) than eNOS or iNOS. It affects the intercellular messenger NO synthesis throughout the brain and body.
T5S0285 Cistanoside A Others
1. Cistanoside A possesses protective activities on CCl4 induced hepatotoxicity in mice, which is involved with increasing free radicals clearing activities, alleviating lipid-overoxidation damage, and improving respirat...
T3847 Asperuloside Asperulosid Others , NO Synthase
Asperuloside (Asperulosid) has anti-inflammatory activity.
T1322 Bendazol Dibazol,Dibazole Dopamine Receptor , NO Synthase
Bendazol (Dibazol) is always used as the drug for hypertension and cerebral Angiospasm.
T5838 L-Canavanine sulfate NO Synthase , NOD
L-Canavanine sulfate is a selective inducible NO synthase inhibitor.
T37696 NOS1-IN-1 nNOS Inhibitor I NOS
NOS1-IN-1(nNOS Inhibitor I) is a potent, selective and cell permeable nNOS inhibitor (Ki: 120 nM).NOS1-IN-1 has a Ki value of 39 μM for eNOS and 325 μM for iNOS.NOS1-IN-1 can be used for the study of neurological disorde...
T22724 Dimaprit dihydrochloride NOS , NO Synthase , Histamine Receptor
Dimaprit dihydrochloride is a selective histamine H2 receptor agonist. Dimaprit dihydrochloride also inhibits nNOS with an IC50 of 49 μM. It can stimulate gastric acid secretion.
T2791 Pectolinarin Apoptosis , Others , NO Synthase , Prostaglandin Receptor , Interleukin
Pectolinarin is a Cirsium isolate with anti-inflammatory activity.
T4808 Agmatine sulfate Agmatine sulfate salt Endogenous Metabolite , NO Synthase , Imidazoline Receptor
Agmatine sulfate (Agmatine sulfate salt) is a bioactive metabolite of the arginine amino acid. It exerts modulatory action at multiple molecular targets, such as neurotransmitter systems, ion channels and nitric oxide sy...
T7597 6-Biopterin L-Biopterin Endogenous Metabolite , NO Synthase , NOD
6-Biopterin (L-Biopterin) is a natural product,is a NO synthase cofactor.
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