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Search Results for " neuroprotective "

Targets

350

Compounds

164

Natural Products

23

Recombinant Proteins

5

Libraries

Cat No. Product Name Synonyms Targets
T8588 Buramate Antibacterial
Buramate is an antipsychotic and anticonvulsant.
T1880 P7C3 Others
The P7C3 class of neuroprotective aminopropyl carbazoles has been shown to block neuronal cell death in models of neurodegeneration. We now show that P7C3 molecules additionally preserve axonal integrity after injury, be...
T3464 PHCCC (-) PHCCC GluR
PHCCC ((-) PHCCC) is a Group I metabotropic glutamate receptor antagonist and a positive allosteric modulator of mGluR4. It also is a potent to antagonism for mGluR2 and mGluR8.
T21687 Conoidin A Parasite
Conoidin A is a cell permeable inhibitor of T. gondii enzyme peroxiredoxin II (TgPrxII) with nematicidal properties. It covalently binds to the peroxidatic Cys47 of TgPrxII, irreversibly inhibiting its hyperperoxidation ...
T8381 Amodiaquine Others , Histone Methyltransferase , Parasite
Amodiaquine is a synthetic aminoquinoline, used to treat malaria.
T2423 P7C3-A20 Others
P7C3-A20 is a derivative of P7C3 that has proneurogenic and neuroprotective activity.
T2343 AS601245 JNK
AS601245 is an inhibitor of the c-Jun NH2-terminal kinase (JNK), with neuroprotective properties.
T8849 PF-9601N MAO
PF-9601N showed high potency and selectivity as a MAO-BI (monoamine oxidase type B inhibitor) and also demonstrated remarkable neuroprotective properties in several in vivo and cellular models of PD.
T29123 VU0152099 VU 0152099,VU-0152099 AChR
VU0152099 is a potent and selective M4 mAChR allosteric potentiator(EC50 = 380 ± 93 nM).
T7683 Adenosine amine congener ADAC Adenosine Receptor
Adenosine amine congener (ADAC) (ADAC) is an agonist of selective A1 adenosine receptor,.
T21919 UCF 101 Apoptosis
UCF 101 is a specific inhibitor of HtrA2 and reduces apoptosis in PC12 cells.
T23348 SEN12333 SEN 12333 AChR
SEN12333 is an α7 nicotinic acetylcholine receptor (nAChR) agonist
T22749 DR2313 DR 2313 PARP
DR2313 is a competitive inhibitor of poly(ADP-ribose) polymerase (IC50: 0.20 and 0.24 μM for PARP-1 and PARP-2 respectively). It also has neuroprotective.
T39341 FCPR03 PDE
FCPR03 is a selective inhibitor of phosphodiesterase 4 (PDE4) with IC50s of 31 nM, 47 nM, and 60 nM for PDE4B1, PDE4D7, and PDE4 catalytic domain, respectively. FCPR03 has neuroprotective, anti-inflammatory, and antidepr...
T2022 CZC-54252 CZC54252,CZC 54252 LRRK2
CZC-54252 is a potent inhibitor of LRRK2.
T2009 SB-3CT MMP
SB-3CT is a potent and specific gelatinase inhibitor for MMP-2(Ki=13.9 nM) and MMP-9(Ki=600 nM).
T4283 SRI-011381 TGF-beta/Smad
SRI-011381, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease.
T39202 CZC-54252 hydrochloride LRRK2
CZC-54252 hydrochloride is a selective inhibitor of LRRK2 with IC50s of 1.85 nM and 1.28 nM for wild-type and G2019S LRRK2. CZC-54252 hydrochloride has a neuroprotective activity and attenuates G2019S LRRK2-induced human...
T5326 Sugammadex sodium Org25969,Sugammadex (sodium) Others
Sugammadex sodium (Org25969) , a synthetic derivative of γ-cyclodextrin, is a steroid-based neuromuscular blocker reversing agent.
T8551 Nitrobenzylthioinosine NBMPR AChR , Adenosine Receptor
Nitrobenzylthioinosine (NBMPR) is an inhibitor of ENT1 transporter that binds to ENT1 transporter with high affinity.
T4113 NBQX FG9202,NBQX disodium salt GluR , iGluR
NBQX (FG9202) is a potent, selective and competitive AMPA receptor antagonist. Neuroprotective and anticonvulsant; active in vivo.
T1993 J-147 J147 Epigenetic Reader Domain , Dopamine Receptor , Monoamine Oxidase
J-147 is an experimental drug with reported effects against both Alzheimer's disease and ageing in mouse models of accelerated aging. It is a curcumin derivative and a potent neurogenic and neuroprotective drug candidate...
T7512 BMS-191011 BMS-A Potassium Channel
BMS-191011 (BMS-A) is an activator of large-conductance calcium-activated potassium (BKCa) channels ,effective in stroke models
T6726 VU0361737 ML-128,VU 0361737 GluR
VU0361737 (ML-128) is a specific positive allosteric modulator (PAM) of mGlu4 receptor.The EC50 of VU 0361737 is 240 nM for the human receptors. The EC50 of VU 0361737 is110 nM for rat receptors.It exhibits weak activity...
T1308 Orphenadrine hydrochloride Mebedrol,Mephenamin Sodium Channel , NMDAR , Norepinephrine , iGluR , Histamine Receptor
Orphenadrine hydrochloride (Mephenamin) is a muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.
T6912 NU1025 NSC 696807 PARP
NU1025 (NSC-696807) is a potent PARP inhibitor with IC50 of 400 nM.
T7780 Blarcamesine AE-37,AVex-73 AChR
Blarcamesine (AVex-73) is a muscarinic M1 agonist potentially for the treatment of Alzheimer's disease.
T14991 CMS-121 CMS121 Acetyl-CoA Carboxylase
CMS-121, a quinolone derivative, is an orally active acetyl-CoA carboxylase 1 (ACC1) inhibitor. CMS-121 protects HT22 cells against ischemia and oxidative damage (EC50: 7 nM and 200 nM). CMS-121 shows strong neuroprotect...
T11393 GET73 Gamma hydroxybutyric acid analogue,GET 73 GluR
GET73 (Gamma hydroxybutyric acid analogue) is an negative allosteric modulator of mGluR5. GET73 is a naturally occurring neurotransmitter. GET73 has anti-alcohol and anxiolytic properties.
T0333 Aniracetam Ro 13-5057 Dopamine Receptor , 5-HT Receptor , GluR , AChR , iGluR
Aniracetam (Ro 13-5057)(Ro 13-5057), a nootropic and neuroprotective drug, selectively modulates the AMPA receptor and nAChR.
T2371 Emapunil AC-5216,XBD-173 Others
Emapunil (XBD-173) is an anxiolytic drug which acts as a selective agonist at the peripheral benzodiazepine receptor, also known as the mitochondrial 18 kDa translocator protein or TSPO.
T0957 Isradipine PN 200-110 Calcium Channel , Autophagy
Isradipine (PN 200-110) is a dihydropyridine calcium channel blockers with antihypertensive and vasodilator activities. Isradipine blocks the calcium entry through the calcium ion channels of coronary and peripheral vasc...
T22323 Enoxaparin sodium Thrombin
Enoxaparin sodium is a low-molecular-weight heparin (LMWH) that has recently been approved by the US FDA for use in patients with medically managed ST-segment myocardial infarction (STEMI), or STEMI with subsequent percu...
T6618 Orphenadrine Citrate Flexon,Flexoject,Banflex AChR , iGluR
Orphenadrine Citrate (Flexon) is a skeletal muscle relaxant, it acts in the central nervous system to produce its muscle relaxant effects.
T22051 BU 224 hydrochloride Imidazoline Receptor
BU 224 hydrochloride is a selective imidazoline I(2) binding site ligand and has antinociceptive and antidepressant-like activities.
T2607 MSDC 0160 CAY10415,Mitoglitazone,MSDC0160,MSDC-0160 Others , IGF-1R , Mitochondrial Metabolism
MSDC 0160 (CAY10415) is a prototype mTOT-modulating insulin sensitizer being used in trials studying the treatment of Type 2 Diabetes and Alzheimer's Disease.
T6504 Flupirtine maleate Katadolon maleate Potassium Channel , NMDAR , iGluR
Flupirtine maleate (Katadolon maleate), a centrally acting non-opioid analgesia, is the salt form of Flupirtine. It is an NMDA receptor antagonist , and also a specific neuronal potassium channel opener.
T6478 Donepezil Hydrochloride Aricept,BNAG,E2020,Donepezil HCl AChR , AChE
Donepezil HCl(Aricept) is a selective and effective AChE inhibitor for bAChE and hAChE (IC50: 8.12/11.6 nM).
T14983 Clomethiazole Distraneurin,Chlormethiazole,5-(2-CHLOROETHYL)-4-METHYLTHIAZOLE P450 , GABA Receptor
Clomethiazole (Distraneurin) is an orally active GABAA agonist and it is an anticonvulsant agent. It also has the potential for treating convulsive status epilepticus. Chlormethiazole inhibits cytochrome P450 isoforms: C...
T1158 Phenoxybenzamine hydrochloride NCI-c01661,NSC 37448,Phenoxybenzamine HCl CaMK , Adrenergic Receptor
Phenoxybenzamine hydrochloride (NCI-c01661) is the hydrochloride salt form of phenoxybenzamine, a synthetic, dibenzamine alpha-adrenergic antagonist with antihypertensive and vasodilatory properties. Phenoxybenzamine non...
T9776 TRPM4 inhibitor 8 TRP/TRPV Channel
TRPM4 inhibitor 8 is an inhibitor of Transient receptor potential melastatin 4(TRPM4) which contributes to viability, migration, cell cycle shift, and adhesion.
T0381 Amodiaquine dihydrochloride dihydrate Amodiaquine hydrochloride,Amodiaquin dihydrochloride dihydrate Histone Methyltransferase , Parasite , Histamine Receptor
Amodiaquine dihydrochloride dihydrate (Amodiaquine hydrochloride) is the hydrochloride salt of amodiaquine, an orally active 4-aminoquinoline derivative with antimalarial and anti-inflammatory properties.
T9157 GP130 receptor agonist-1 N-(4-Fluorophenyl)-4-phenyl-2-thiazolami Interleukin
GP130 receptor agonist-1 (N-(4-Fluorophenyl)-4-phenyl-2-thiazolami) is a potent, brain-penetrant and orally active GP130 receptor agonist.
T22674 Co 101244 hydrochloride 4-Piperidinol, 1-[2-(4-hydroxyphenoxy)ethyl]-4-[(4-Methylphenyl)Methyl]-,hydrochloride NMDAR
Co 101244 hydrochloride (4-Piperidinol, 1-[2-(4-hydroxyphenoxy)ethyl]-4-[(4-Methylphenyl)Methyl]-,hydrochloride) is an NR2B-containing NMDA receptor antagonist.
T5129 SRI-011381 hydrochloride SRI-011381 hydrochloride [1629138-41-5(free base)] TGF-beta/Smad
SRI-011381 hydrochloride, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease.
T23046 N-tert-butyl-α-Phenylnitrone (Z)-N-benzylidene-2-Methylpropan-2-aMine oxide ROS , COX
N-tert-butyl-α-Phenylnitrone ((Z)-N-benzylidene-2-Methylpropan-2-aMine oxide) inhibits COX2 catalytic activity. N-tert-butyl-α-Phenylnitrone((Z)-N-benzylidene-2-Methylpropan-2-aMine oxide) possesses potent reactive oxyge...
T8435 YM90K YM90K hydrochloride,6-(1H-imidazol-1-yl)-7-nitro-2,3(1H,4H)- GluR , iGluR
YM90K (6-(1H-imidazol-1-yl)-7-nitro-2,3(1H,4H)-) hydrochloride is an antagonist of AMPA receptor.
T12617L (R)​-​CR8 (R)-CR8,(R)-Isomer,CR8 Apoptosis , CDK
(R)-CR8 ((R)-Isomer) is a potent and selective CDK inhibitor.
T1101 Minocycline hydrochloride Minocycline HCl HIF/HIF Prolyl-Hydroxylase , Antibacterial , Antibiotic
Minocycline hydrochloride (Minocycline HCl) is a tetracycline antibiotic with excellent absorption and tissue penetration that is used for several bacterial infections as well as treatment of acne. Minocycline hydrochlor...
T6823 E3330 HIF/HIF Prolyl-Hydroxylase , DNA/RNA Synthesis
E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.

Compounds

Buramate
T8588
Synonym:
Target: Antibacterial
P7C3
T1880
Synonym:
Target: Others
PHCCC
T3464
Synonym: (-) PHCCC
Target: GluR
Conoidin A
T21687
Synonym:
Target: Parasite
Amodiaquine
T8381
Synonym:
Target: Others, Histone Methyltransferase, Parasite
P7C3-A20
T2423
Synonym:
Target: Others
AS601245
T2343
Synonym:
Target: JNK
PF-9601N
T8849
Synonym:
Target: MAO
VU0152099
T29123
Synonym: VU 0152099,VU-0152099
Target: AChR
Adenosine amine congener
T7683
Synonym: ADAC
Target: Adenosine Receptor
UCF 101
T21919
Synonym:
Target: Apoptosis
SEN12333
T23348
Synonym: SEN 12333
Target: AChR
DR2313
T22749
Synonym: DR 2313
Target: PARP
FCPR03
T39341
Synonym:
Target: PDE
CZC-54252
T2022
Synonym: CZC54252,CZC 54252
Target: LRRK2
SB-3CT
T2009
Synonym:
Target: MMP
SRI-011381
T4283
Synonym:
Target: TGF-beta/Smad
CZC-54252 hydrochloride
T39202
Synonym:
Target: LRRK2
Sugammadex sodium
T5326
Synonym: Org25969,Sugammadex (sodium)
Target: Others
Nitrobenzylthioinosine
T8551
Synonym: NBMPR
Target: AChR, Adenosine Receptor
NBQX
T4113
Synonym: FG9202,NBQX disodium salt
Target: GluR, iGluR
J-147
T1993
Synonym: J147
Target: Epigenetic Reader Domain, Dopamine Receptor, Monoamine Oxidase
BMS-191011
T7512
Synonym: BMS-A
Target: Potassium Channel
VU0361737
T6726
Synonym: ML-128,VU 0361737
Target: GluR
Orphenadrine hydrochloride
T1308
Synonym: Mebedrol,Mephenamin
Target: Sodium Channel, NMDAR, Norepinephrine, iGluR, Histamine Receptor
NU1025
T6912
Synonym: NSC 696807
Target: PARP
Blarcamesine
T7780
Synonym: AE-37,AVex-73
Target: AChR
CMS-121
T14991
Synonym: CMS121
Target: Acetyl-CoA Carboxylase
GET73
T11393
Synonym: Gamma hydroxybutyric acid analogue,GET 73
Target: GluR
Aniracetam
T0333
Synonym: Ro 13-5057
Target: Dopamine Receptor, 5-HT Receptor, GluR, AChR, iGluR
Emapunil
T2371
Synonym: AC-5216,XBD-173
Target: Others
Isradipine
T0957
Synonym: PN 200-110
Target: Calcium Channel, Autophagy
Enoxaparin sodium
T22323
Synonym:
Target: Thrombin
Orphenadrine Citrate
T6618
Synonym: Flexon,Flexoject,Banflex
Target: AChR, iGluR
BU 224 hydrochloride
T22051
Synonym:
Target: Imidazoline Receptor
MSDC 0160
T2607
Synonym: CAY10415,Mitoglitazone,MSDC0160,MSDC-0160
Target: Others, IGF-1R, Mitochondrial Metabolism
Flupirtine maleate
T6504
Synonym: Katadolon maleate
Target: Potassium Channel, NMDAR, iGluR
Donepezil Hydrochloride
T6478
Synonym: Aricept,BNAG,E2020,Donepezil HCl
Target: AChR, AChE
Clomethiazole
T14983
Synonym: Distraneurin,Chlormethiazole,5-(2-CHLOROETHYL)-4-METHYLTHIAZOLE
Target: P450, GABA Receptor
Phenoxybenzamine hydrochloride
T1158
Synonym: NCI-c01661,NSC 37448,Phenoxybenzamine HCl
Target: CaMK, Adrenergic Receptor
TRPM4 inhibitor 8
T9776
Synonym:
Target: TRP/TRPV Channel
Amodiaquine dihydrochloride dihydrate
T0381
Synonym: Amodiaquine hydrochloride,Amodiaquin dihydrochloride dihydrate
Target: Histone Methyltransferase, Parasite, Histamine Receptor
GP130 receptor agonist-1
T9157
Synonym: N-(4-Fluorophenyl)-4-phenyl-2-thiazolami
Target: Interleukin
Co 101244 hydrochloride
T22674
Synonym: 4-Piperidinol, 1-[2-(4-hydroxyphenoxy)ethyl]-4-[(4-Methylphenyl)Methyl]-,hydrochloride
Target: NMDAR
SRI-011381 hydrochloride
T5129
Synonym: SRI-011381 hydrochloride [1629138-41-5(free base)]
Target: TGF-beta/Smad
N-tert-butyl-α-Phenylnitrone
T23046
Synonym: (Z)-N-benzylidene-2-Methylpropan-2-aMine oxide
Target: ROS, COX
YM90K
T8435
Synonym: YM90K hydrochloride,6-(1H-imidazol-1-yl)-7-nitro-2,3(1H,4H)-
Target: GluR, iGluR
(R)​-​CR8
T12617L
Synonym: (R)-CR8,(R)-Isomer,CR8
Target: Apoptosis, CDK
Minocycline hydrochloride
T1101
Synonym: Minocycline HCl
Target: HIF/HIF Prolyl-Hydroxylase, Antibacterial, Antibiotic
E3330
T6823
Synonym:
Target: HIF/HIF Prolyl-Hydroxylase, DNA/RNA Synthesis
1 2 3 4 5 6 7
Cat No. Product Name Synonyms Targets
TN1076 Oleonuezhenide Others
Oleonuezhenide is a natural product from Chinese formula Ligustrum lucidum, exerts neuroprotective effects and also considered as treatment of osteoporosis.
TMS1743 Salvigenin MAO , Autophagy , ROS Kinase
Salvigenin is a potent hMAO-A inhibitor, has neuroprotective, antitumor and immunomodulatory effects.
T6S2227 Spinosin Flavoayamenin Others
1. Spinosin (Flavoayamenin) ameliorated memory impairment induced through AβO, the serotonergic neurotransmitter system, and these effects were regulated, in part, through neuroprotective activity via the anti-inflammato...
TN1772 Isoastilbin Anti-infection , Tyrosinase , Antibacterial
Isoastilbin is a dihydroflavonol glycoside compound in Rhizoma Smilacis glabrae and Astragalus membranaceus. Isoastilbin inhibits glucosyltransferase (GTase) with an IC50 value of 54.3 μg/mL, Isoastilbin has anti-acne an...
T3236 Solanesol Betulanonaprenol,Nonaisoprenol Others , Endogenous Metabolite , Antibacterial
Solanesol (Betulanonaprenol) is a phytochemical present in tobacco leaf. Starting material for synthesis of co-enzyme Q10. Exhibits antiulcer activity.
T3769 Tenuifolin Others , Beta-Secretase , AChE
Tenuifolin has no inherent toxicity to either the transfected or wild type cells at the effective concentrations, it inhibits amyloid-β secretion in vitro.
TN2085 Piperlonguminine Anti-infection , Antibacterial , Antifungal
Piperlonguminine is an alkaloid amide isolated from the Piper species. Piperlonguminine shows anti-inflammatory, antitumor, neuroprotective, anti-platelet, anti-melanogenic, antifungal and antibacterial activities.Piperl...
T3S0195 Nootkatone AMPK
1. Nootkatone can provide effective tick control. 2. (+)-Nootkatone has antiallergic, anti-inflammatory, and antiplatelet activities. 3. Nootkatone can prevent obesity and improve physical performance through AMPK activa...
TN2082 Pinostrobin Beta Amyloid , IL Receptor , Serine/threonin kinase , TNF
Pinostrobin, a potent flavonoid inducer, exerts a neuroprotective effect against Aα²(25-35)-induced neurotoxicity in PC12 cells, at least in part, via inhibiting oxidative damage and calcium overload, as well as suppress...
T12095 Monomethyl fumarate GPR , Drug Metabolite
Monomethyl fumarate is a potent agonist of GPR109A .
T2786 Oxysophocarpine Prostaglandin Receptor
Oxysophocarpine is extracted from Sophra flavescens Ait.
T6S0721 Orientin Lutexin,Luteolin-8-glucoside Others
1. Orientin (Luteolin-8-glucoside) may be regarded as a candidate therapeutic agent for treatment of vascular inflammatory diseases via inhibition of the HMGB1 signaling pathway. 2. Orientin protects vascular barrier int...
T2780 Catalpol Catalpinoside,Digitalis purpurea L Others , HBV
Catalpol (Catalpinoside) is an iridoid glycoside with neuroprotective, anti-inflammatory, and anti-hepatitis virus effects.
T3866 Macelignan Anwuligan,(+)-Anwulignan Others , COX
Macelignan (Anwuligan) is a lignan isolated from nutmeg with antimicrobial and anticariogenic activity against Streptococcus mutans and other streptococcus species.
T5654 Musk ketone Others
Musk ketone can induce the growth repression and the apoptosis of cancer cells. Musk ketone increases activity of glutathione S-transferase and thus may prove to be useful cancer chemoprotectant.
T3773 Oxypaeoniflorin Oxypaeoniflora Others
Oxypaeoniflorin (Oxypaeoniflora) is a natural product derived from Radix Paeoniae Rubra and Radix Paeoniae Alba.
T6S1653 Albiflorin Alibiflorin Reactive Oxygen Species
1. Albiflorin (Alibiflorin) has anticonvulsant effect for pain relief. 2. Albiflorin and paeoniflorin has neuroprotective action against Glu toxicity. 3. Albiflorin and paeoniflorin significantly ameliorated Glu-induced ...
T4S2126 Ginkgetin Apoptosis , Wnt/beta-catenin , COX , STAT , Autophagy
1. Ginkgetin has anti-influenza virus and anti-fungal activities. 2. Ginkgetin has anti-inflammatory activity, can down-regulates COX-2 induction in vivo against skin inflammatory responses. 3. Ginkgetin is a good STAT3 ...
TN2423 Safranal Antioxidant
Safranal is the special volatile aroma compound of saffron
T7983 Isoborneol DL-Isoborneol HSV
Isoborneol (DL-Isoborneol) is a monoterpene alcohol, with neuroprotective and antiviral activities
T1032 Erythromycin E-Mycin ribosome , Antibacterial , Antibiotic
Erythromycin (E-Mycin) is a Macrolide and Macrolide Antimicrobial. The physiologic effect of erythromycin is by means of Decreased Sebaceous Gland Activity.
TN1911 Marein transporter , Akt , HDAC , AMPK
Marein shows neuroprotective effect on PC12 cell damage induced by methylglyoxal, which is due to a reduction of damage to mitochondria function and activation of the AMPK signal pathway, it may be a potent compound for ...
T3416 Aucubin Aucuboside,Rhinanthin IL Receptor , NF-κB , Antibacterial
Aucubin (Rhinanthin) is an iridoid glycoside with anti-inflammatory, anti-microbial, anti-algesic as well as anti-tumor activities.
T0795 Rutin Quercetin 3-O-rutinoside,Rutoside Beta Amyloid , Prostaglandin Receptor , Autophagy
Rutin (Quercetin 3-O-rutinoside), a flavonoid, has a variety of biological activities including antiallergic, anti-inflammatory, antiproliferative, and anticarcinogenic properties.
T2899 Liquiritin Liquiritigenin-4'-O-glucoside,Liquiritoside Reactive Oxygen Species
Liquiritin (Liquiritigenin-4'-O-glucoside) (LIQ) is a main component among the licorice flavonoids, and possesses anti-inflammatory and anti-cancer abilities.
T8516 Levomenol (-)-α-BISABOLOL Others
Levomenol ((-)-α-BISABOLOL) is a sesquiterpene alcohol that has been found in the essential oils of several aromatic plants, with exerts antioxidant, anti-inflammatory, and anti-apoptotic activities.
T2800 L-Theanine Apoptosis , Others
L-Theanine is a relaxing and nondietary amino acid found pretty much exclusively in teas from Camellia sinensis and is known to promote relaxation without sedation.
T0492 Dimethyl fumarate DMF Reactive Oxygen Species , HIV Protease , Nrf2 , Endogenous Metabolite , Autophagy
Dimethyl fumarate (DMF), a fumarate derivative, is used as antiinflammatory and immunomodulatory agent.
T0437 Inosine INO 495,NSC 20262 ROS , Endogenous Metabolite , Adenosine Receptor
Inosine (NSC-20262) is a purine nucleoside that has hypoxanthine linked by the N9 nitrogen to the C1 carbon of ribose. It has immunomodulatory, neuroprotective, and analgesic properties.
T6780 Benzamide Amid kyseliny benzoove,Phenylcarboxyamide,Benzoylamide PARP , Endogenous Metabolite
Benzamide (Amid kyseliny benzoove), an inhibitor of poly(ADP-ribose) polymerase, is a derivative of benzoic acid.
T26288 Clovamide trans-Clovamide,N-trans-Caffeoy-L-dopa Apoptosis , Influenza Virus , ROS , Antibacterial
Trans-Clovamide (trans-Clovamide) is a naturally occurring caffeoyl conjugate identified in the antioxidant polyphenolic fraction of cocoa (T. cacao L.) Trans-Clovamide is a potent antioxidantand that has shown neuroprot...
T5728 OsMundacetone 4-(3,4-Dihydroxyphenyl)-3-buten-2-one Apoptosis , Reactive Oxygen Species
OsMundacetone (4-(3,4-Dihydroxyphenyl)-3-buten-2-one) is a natual product isolated from Rhizoma osmundae.
T3933 Jatrorrhizine Yatrorizine,neprotin MAO , 5-HT Receptor , Antibacterial , AChE
Jatrorrhizine (neprotin) is a protoberberine alkaloid isolated from Enantia chlorantha (Annonaceae) and other species. It was found to have antimicrobial and antifungal activity. It binds and noncompetitively inhibits mo...
TN2883 3',4'-Dimethoxyflavone Others , PARP
3',4'-Dimethoxyflavone is a standard compound of flavonoids with numerous medicinal activities.
T22417 Rutin hydrate Rutoside,Sophorin,Quercetin-3-O-rutinoside Beta Amyloid , Others , Autophagy
Rutin hydrate (Sophorin), a kind of glycoside, widely exists in many plants including citrus fruit.
T6S1525 3,4-Dicaffeoylquinic acid Isochlorogenic acid B Apoptosis , Antioxidant , Influenza Virus , Endogenous Metabolite
3,4-Dicaffeoylquinic acid (Isochlorogenic acid B) has antioxidant activity.
T2902 Costunolide Costus lactone,NSC 106404,Costunolid,(+)-Costunolide Apoptosis , Endogenous Metabolite , Telomerase
Costunolide (Costus lactone) has anti-inflammatory and anti-oxidant properties and mediates apoptosis.
T3026 (-)-Huperzine A HupA,Huperzine A Apoptosis , AChR , AChE , iGluR
(-)-Huperzine A (HupA) , an active Lycopodium alkaloid extracted from the traditional Chinese herb, is a potent, selective and reversible acetylcholinesterase (AChE) inhibitor and has been widely used in China for the tr...
T3S1068 Oxyresveratrol trans-Oxyresveratrol,2,3',4,5'-tetrahydroxystilbene,Tetrahydroxystilbene Tyrosinase , Autophagy , HSV
1. Oxyresveratro can inhibit tyrosinase activity. 2. Oxyresveratro is useful to trauma models, as toxicity to glia could be beneficial by inhibiting reactive gliosis. 3. Oxyresveratrol (trans-Oxyresveratrol) has antioxid...
T4S1659 Xanthotoxol 8-Hydroxypsoralen,8-Hydroxyfuranocoumarin,Psoralen,8-Hydroxypsoralene Reactive Oxygen Species , 5-HT Receptor , Endogenous Metabolite
Xanthotoxol (Psoralen) is a biologically active linear furocoumarin, shows strong pharmacological activities as anti-inflammatory, antioxidant, 5-HT antagonistic, and neuroprotective effects.
T4912 Jatrorrhizine chloride Yatrorhizine chloride,Neprotine chloride Others , 5-HT Receptor , OCT , Antibacterial , AChE
Jatrorrhizine chloride (Neprotine chloride) is a potent and orally active uptake-2 transporter inhibitor. It exhibits a critical neuroprotective role in H2O2-induced apoptosis via inhibition of the MAPK pathway in HT22 h...
T4036 Solasodine Solancarpidine,Purapuridine,Solasodin Apoptosis , Others , E1/E2/E3 Enzyme , Antifungal
Solasodine (Purapuridine)(Purapuridine) is a poisonous alkaloid chemical compound that occurs in plants of the Solanaceae family. Solasodine showed selective cytotoxicity against cervical cancer cell line (HeLa) and huma...
T9454 4-Hydroxyestrone Estrogen Receptor/ERR , Endogenous Metabolite
4-Hydroxyestrone, an endogenous estrogen metabolite, can strongly protect neuronal cells against oxidative damage.
T3388 Calycosin-7-O-β-D-glucoside calycosin-7-O-beta-D-glucopyranoside,Calycosin-7-O-beta-D-glucoside MMP , Reactive Oxygen Species
Calycosin-7-O-β-D-glucoside (calycosin-7-O-beta-D-glucopyranoside) possesses a protective effect on rat hepatocytes, an inhibitory effect on COX-2 activity. Calycosin 7-O-β-D-glucoside has antimicrobial activity. Calycos...
T36857L Premarin Estrone 3-sulfate,Estrone sulfate Estrogen Receptor/ERR
Premarin (Estrone 3-sulfate) is an an estrogen sulfate with neuroprotective actions during traumatic brain injury.
T3697 3',6-Disinapoylsucrose Disinapoyl sucrose,3,6'-Disinapoyl sucrose BCL , Epigenetic Reader Domain
3',6-Disinapoylsucrose (Disinapoyl sucrose) shows the neuroprotective effect and antidepressive activity in rats.
T0136 Citicoline CDP-Choline,Citicholine,cytidine 5'-diphosphocholine,cytidine diphosphate-choline Apoptosis , Dopamine Receptor , Endogenous Metabolite
Citicoline (CDP-Choline) is an intermediate in the synthesis of phosphatidylcholine, a component of cell membranes. Citicoline exerts neuroprotective effects.
Fr12596 3-Acetylcoumarin Others
3-Acetylcoumarin as a practical ligand for copper-catalyzed CN coupling reactions at room temperature. It has neuroprotective and acaricidal properties.
T65135 Kynurenic acid Fibrostop 2,Quinurenic acid GPR , GluR , NMDAR
Kynurenic acid (Quinurenic acid) is an endogenous tryptophan active metabolite, a triple antagonist of NMDA, glutamate, α7 nicotinic acetylcholine receptor, and an agonist of GPR35/CXCR8 with neuroprotective and anticonv...
T8200 Ginkgolide K AMPK , Autophagy
Ginkgolide K induces protective autophagy through the AMPK/mTOR/ULK1 signalling pathway. It possesses neuroprotective activity.
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Natural Products

Oleonuezhenide
TN1076
Synonym:
Target: Others
Salvigenin
TMS1743
Synonym:
Target: MAO, Autophagy, ROS Kinase
Spinosin
T6S2227
Synonym: Flavoayamenin
Target: Others
Isoastilbin
TN1772
Synonym:
Target: Anti-infection, Tyrosinase, Antibacterial
Solanesol
T3236
Synonym: Betulanonaprenol,Nonaisoprenol
Target: Others, Endogenous Metabolite, Antibacterial
Tenuifolin
T3769
Synonym:
Target: Others, Beta-Secretase, AChE
Piperlonguminine
TN2085
Synonym:
Target: Anti-infection, Antibacterial, Antifungal
Nootkatone
T3S0195
Synonym:
Target: AMPK
Pinostrobin
TN2082
Synonym:
Target: Beta Amyloid, IL Receptor, Serine/threonin kinase, TNF
Monomethyl fumarate
T12095
Synonym:
Target: GPR, Drug Metabolite
Oxysophocarpine
T2786
Synonym:
Target: Prostaglandin Receptor
Orientin
T6S0721
Synonym: Lutexin,Luteolin-8-glucoside
Target: Others
Catalpol
T2780
Synonym: Catalpinoside,Digitalis purpurea L
Target: Others, HBV
Macelignan
T3866
Synonym: Anwuligan,(+)-Anwulignan
Target: Others, COX
Musk ketone
T5654
Synonym:
Target: Others
Oxypaeoniflorin
T3773
Synonym: Oxypaeoniflora
Target: Others
Albiflorin
T6S1653
Synonym: Alibiflorin
Target: Reactive Oxygen Species
Ginkgetin
T4S2126
Synonym:
Target: Apoptosis, Wnt/beta-catenin, COX, STAT, Autophagy
Safranal
TN2423
Synonym:
Target: Antioxidant
Isoborneol
T7983
Synonym: DL-Isoborneol
Target: HSV
Erythromycin
T1032
Synonym: E-Mycin
Target: ribosome, Antibacterial, Antibiotic
Marein
TN1911
Synonym:
Target: transporter, Akt, HDAC, AMPK
Aucubin
T3416
Synonym: Aucuboside,Rhinanthin
Target: IL Receptor, NF-κB, Antibacterial
Rutin
T0795
Synonym: Quercetin 3-O-rutinoside,Rutoside
Target: Beta Amyloid, Prostaglandin Receptor, Autophagy
Liquiritin
T2899
Synonym: Liquiritigenin-4'-O-glucoside,Liquiritoside
Target: Reactive Oxygen Species
Levomenol
T8516
Synonym: (-)-α-BISABOLOL
Target: Others
L-Theanine
T2800
Synonym:
Target: Apoptosis, Others
Dimethyl fumarate
T0492
Synonym: DMF
Target: Reactive Oxygen Species, HIV Protease, Nrf2, Endogenous Metabolite, Autophagy
Inosine
T0437
Synonym: INO 495,NSC 20262
Target: ROS, Endogenous Metabolite, Adenosine Receptor
Benzamide
T6780
Synonym: Amid kyseliny benzoove,Phenylcarboxyamide,Benzoylamide
Target: PARP, Endogenous Metabolite
Clovamide
T26288
Synonym: trans-Clovamide,N-trans-Caffeoy-L-dopa
Target: Apoptosis, Influenza Virus, ROS, Antibacterial
OsMundacetone
T5728
Synonym: 4-(3,4-Dihydroxyphenyl)-3-buten-2-one
Target: Apoptosis, Reactive Oxygen Species
Jatrorrhizine
T3933
Synonym: Yatrorizine,neprotin
Target: MAO, 5-HT Receptor, Antibacterial, AChE
3',4'-Dimethoxyflavone
TN2883
Synonym:
Target: Others, PARP
Rutin hydrate
T22417
Synonym: Rutoside,Sophorin,Quercetin-3-O-rutinoside
Target: Beta Amyloid, Others, Autophagy
3,4-Dicaffeoylquinic acid
T6S1525
Synonym: Isochlorogenic acid B
Target: Apoptosis, Antioxidant, Influenza Virus, Endogenous Metabolite
Costunolide
T2902
Synonym: Costus lactone,NSC 106404,Costunolid,(+)-Costunolide
Target: Apoptosis, Endogenous Metabolite, Telomerase
(-)-Huperzine A
T3026
Synonym: HupA,Huperzine A
Target: Apoptosis, AChR, AChE, iGluR
Oxyresveratrol
T3S1068
Synonym: trans-Oxyresveratrol,2,3',4,5'-tetrahydroxystilbene,Tetrahydroxystilbene
Target: Tyrosinase, Autophagy, HSV
Xanthotoxol
T4S1659
Synonym: 8-Hydroxypsoralen,8-Hydroxyfuranocoumarin,Psoralen,8-Hydroxypsoralene
Target: Reactive Oxygen Species, 5-HT Receptor, Endogenous Metabolite
Jatrorrhizine chloride
T4912
Synonym: Yatrorhizine chloride,Neprotine chloride
Target: Others, 5-HT Receptor, OCT, Antibacterial, AChE
Solasodine
T4036
Synonym: Solancarpidine,Purapuridine,Solasodin
Target: Apoptosis, Others, E1/E2/E3 Enzyme, Antifungal
4-Hydroxyestrone
T9454
Synonym:
Target: Estrogen Receptor/ERR, Endogenous Metabolite
Calycosin-7-O-β-D-glucoside
T3388
Synonym: calycosin-7-O-beta-D-glucopyranoside,Calycosin-7-O-beta-D-glucoside
Target: MMP, Reactive Oxygen Species
Premarin
T36857L
Synonym: Estrone 3-sulfate,Estrone sulfate
Target: Estrogen Receptor/ERR
3',6-Disinapoylsucrose
T3697
Synonym: Disinapoyl sucrose,3,6'-Disinapoyl sucrose
Target: BCL, Epigenetic Reader Domain
Citicoline
T0136
Synonym: CDP-Choline,Citicholine,cytidine 5'-diphosphocholine,cytidine diphosphate-choline
Target: Apoptosis, Dopamine Receptor, Endogenous Metabolite
3-Acetylcoumarin
Fr12596
Synonym:
Target: Others
Kynurenic acid
T65135
Synonym: Fibrostop 2,Quinurenic acid
Target: GPR, GluR, NMDAR
Ginkgolide K
T8200
Synonym:
Target: AMPK, Autophagy

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-00991 LIFR Protein, Human, Recombinant (His) Human HEK293
LIFR (leukemia inhibitory factor receptor) belongs to the family of cytokine receptors. LIFR forms a high-affinity receptor complex with gp130, which mediates the activity of LIF (leukemia inhibitory factor) and thus aff...
TMPY-00443 EPO/Erythropoietin Protein, Mouse, Recombinant Mouse HEK293
Erythropoietin is a member of the EPO / TPO family. It is a secreted, glycosylated cytokine composed of four alpha helical bundles. Erythropoietin can be found in the plasma and regulates red cell production by promoting...
TMPY-00639 EPO/Erythropoietin Protein, Human, Recombinant (hFc) Human HEK293
Erythropoietin is a member of the EPO / TPO family. It is a secreted, glycosylated cytokine composed of four alpha helical bundles. Erythropoietin can be found in the plasma and regulates red cell production by promoting...
TMPY-05493 LIFR Protein, Human, Recombinant (hFc) Human HEK293
LIFR (leukemia inhibitory factor receptor) belongs to the family of cytokine receptors. LIFR forms a high-affinity receptor complex with gp130, which mediates the activity of LIF (leukemia inhibitory factor) and thus aff...
TMPY-00834 IGF1R/CD221 Protein, Human, Recombinant (His) Human HEK293
The insulin-like growth factor-1 receptor (IGF1R) is a transmembrane tyrosine kinase involved in several biological processes including cell proliferation, differentiation, DNA repair, and cell survival. This a disulfide...
TMPK-00810 TPA Protein, Mouse, Recombinant (His) Mouse HEK293
Tissue plasminogen activator (tPA) is the predominant plasminogen activator present in the vascular and nervous systems.t tPA is not only neuroprotective for postnatal primary cortical neurons, but also that the predomin...
TMPY-02446 GAPDH Protein, Human, Recombinant (His) Human E. coli
Glyceraldehyde 3-phosphate dehydrogenase (GAPDH or G3PDH) is an enzyme of about 37kDa that is consisdered as a cellular enzyme involved in glycolysis. It catelyzes the sixth step of glycolysis. Glyceraldehyde-3-phosphate...
TMPY-00506 GAPDH Protein, Mouse, Recombinant (His) Mouse E. coli
Glyceraldehyde 3-phosphate dehydrogenase (GAPDH or G3PDH) is an enzyme of about 37kDa that is consisdered as a cellular enzyme involved in glycolysis. It catelyzes the sixth step of glycolysis. Glyceraldehyde-3-phosphate...
TMPY-02986 EPO/Erythropoietin Protein, Mouse, Recombinant (His) Mouse HEK293
Erythropoietin is a member of the EPO / TPO family. It is a secreted, glycosylated cytokine composed of four alpha helical bundles. Erythropoietin can be found in the plasma and regulates red cell production by promoting...
TMPY-00462 EPO/Erythropoietin Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Erythropoietin is a member of the EPO / TPO family. It is a secreted, glycosylated cytokine composed of four alpha helical bundles. Erythropoietin can be found in the plasma and regulates red cell production by promoting...
TMPY-01597 LIFR Protein, Mouse, Recombinant (His) Mouse HEK293
LIFR (leukemia inhibitory factor receptor) belongs to the family of cytokine receptors. LIFR forms a high-affinity receptor complex with gp130, which mediates the activity of LIF (leukemia inhibitory factor) and thus aff...
TMPY-02073 EPO/Erythropoietin Protein, Rat, Recombinant (His) Rat Baculovirus-Insect Cells
Erythropoietin is a member of the EPO / TPO family. It is a secreted, glycosylated cytokine composed of four alpha helical bundles. Erythropoietin can be found in the plasma and regulates red cell production by promoting...
TMPH-01502 Humanin Protein, Human, Recombinant (GST) Human E. coli
Plays a role as a neuroprotective factor. Protects against neuronal cell death induced by multiple different familial Alzheimer disease genes and amyloid-beta proteins in Alzheimer disease. Mediates its neuroprotective e...
TMPY-06010 LIFR Protein, Human, Recombinant (His), Biotinylated Human HEK293
LIFR (leukemia inhibitory factor receptor) belongs to the family of cytokine receptors. LIFR forms a high-affinity receptor complex with gp130, which mediates the activity of LIF (leukemia inhibitory factor) and thus aff...
TMPY-06892 LIFR Protein, Rhesus, Recombinant (His) Rhesus HEK293
LIFR (leukemia inhibitory factor receptor) belongs to the family of cytokine receptors. LIFR forms a high-affinity receptor complex with gp130, which mediates the activity of LIF (leukemia inhibitory factor) and thus aff...
TMPJ-00990 S100B Protein, Mouse, Recombinant (His) Mouse E. coli
S100-B, is an acidic protein with a molecular weight of 21 kDa belonging to the S100 family. S100-B contains two EF-hand-type calcium-binding motifs separated by a hinge region with a hydrophobic cleft. S100-B plays an i...
TMPY-03306 LIFR Protein, Rat, Recombinant (His) Rat HEK293
LIFR (leukemia inhibitory factor receptor) belongs to the family of cytokine receptors. LIFR forms a high-affinity receptor complex with gp130, which mediates the activity of LIF (leukemia inhibitory factor) and thus aff...
TMPH-01815 Optineurin Protein, Human, Recombinant (E. coli, His) Human E. coli
Plays an important role in the maintenance of the Golgi complex, in membrane trafficking, in exocytosis, through its interaction with myosin VI and Rab8. Links myosin VI to the Golgi complex and plays an important role i...
TMPH-01503 Humanin Protein, Human, Recombinant (hFc) Human HEK293
Plays a role as a neuroprotective factor. Protects against neuronal cell death induced by multiple different familial Alzheimer disease genes and amyloid-beta proteins in Alzheimer disease. Mediates its neuroprotective e...
TMPH-01814 Optineurin Protein, Human, Recombinant (His) Human Baculovirus
Plays an important role in the maintenance of the Golgi complex, in membrane trafficking, in exocytosis, through its interaction with myosin VI and Rab8. Links myosin VI to the Golgi complex and plays an important role i...
TMPY-06195 IGF1R/CD221 Protein, Mouse, Recombinant (His) Mouse HEK293
The insulin-like growth factor-1 receptor (IGF1R) is a transmembrane tyrosine kinase involved in several biological processes including cell proliferation, differentiation, DNA repair, and cell survival. This a disulfide...
TMPY-06905 IGF1R/CD221 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
The insulin-like growth factor-1 receptor (IGF1R) is a transmembrane tyrosine kinase involved in several biological processes including cell proliferation, differentiation, DNA repair, and cell survival. This a disulfide...
TMPY-04360 IGF1R/CD221 Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
The insulin-like growth factor-1 receptor (IGF1R) is a transmembrane tyrosine kinase involved in several biological processes including cell proliferation, differentiation, DNA repair, and cell survival. This a disulfide...
LIFR Protein, Human, Recombinant (His)
TMPY-00991
Species: Human
Expression System: HEK293
EPO/Erythropoietin Protein, Mouse, Recombinant
TMPY-00443
Species: Mouse
Expression System: HEK293
EPO/Erythropoietin Protein, Human, Recombinant (hFc)
TMPY-00639
Species: Human
Expression System: HEK293
LIFR Protein, Human, Recombinant (hFc)
TMPY-05493
Species: Human
Expression System: HEK293
IGF1R/CD221 Protein, Human, Recombinant (His)
TMPY-00834
Species: Human
Expression System: HEK293
tPA Protein, Mouse, Recombinant (His)
TMPK-00810
Species: Mouse
Expression System: HEK293
GAPDH Protein, Human, Recombinant (His)
TMPY-02446
Species: Human
Expression System: E. coli
GAPDH Protein, Mouse, Recombinant (His)
TMPY-00506
Species: Mouse
Expression System: E. coli
EPO/Erythropoietin Protein, Mouse, Recombinant (His)
TMPY-02986
Species: Mouse
Expression System: HEK293
EPO/Erythropoietin Protein, Cynomolgus, Recombinant (His)
TMPY-00462
Species: Cynomolgus
Expression System: HEK293
LIFR Protein, Mouse, Recombinant (His)
TMPY-01597
Species: Mouse
Expression System: HEK293
EPO/Erythropoietin Protein, Rat, Recombinant (His)
TMPY-02073
Species: Rat
Expression System: Baculovirus-Insect Cells
Humanin Protein, Human, Recombinant (GST)
TMPH-01502
Species: Human
Expression System: E. coli
LIFR Protein, Human, Recombinant (His), Biotinylated
TMPY-06010
Species: Human
Expression System: HEK293
LIFR Protein, Rhesus, Recombinant (His)
TMPY-06892
Species: Rhesus
Expression System: HEK293
S100B Protein, Mouse, Recombinant (His)
TMPJ-00990
Species: Mouse
Expression System: E. coli
LIFR Protein, Rat, Recombinant (His)
TMPY-03306
Species: Rat
Expression System: HEK293
Optineurin Protein, Human, Recombinant (E. coli, His)
TMPH-01815
Species: Human
Expression System: E. coli
Humanin Protein, Human, Recombinant (hFc)
TMPH-01503
Species: Human
Expression System: HEK293
Optineurin Protein, Human, Recombinant (His)
TMPH-01814
Species: Human
Expression System: Baculovirus
IGF1R/CD221 Protein, Mouse, Recombinant (His)
TMPY-06195
Species: Mouse
Expression System: HEK293
IGF1R/CD221 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06905
Species: Human
Expression System: HEK293
IGF1R/CD221 Protein, Human, Recombinant (His & GST)
TMPY-04360
Species: Human
Expression System: Baculovirus-Insect Cells
Cat No. Product Name
L5900 CNS-Penetrant Compound Library

516 compounds
A unique collection of 516 CNS-Penetrant compounds for high throughput screening (HTS) and high content screening (HCS);
L6110 Alkaloid Natural Product Library

468 compounds
A unique collection of 468 natural alkaloids can be used for high throughput and high content screening;
L6140 Saccharide and Glycoside Natural Product Library

364 compounds
A unique collection of 364 saccharides and glycosides compounds can be used for HTS and HCS;
L6820 Tobacco Monomer Library

750 compounds
A unique collection of 750 tobacco monomer compounds for high throughput screening and high content screening;
L6750 PBCRBS Traditional Chinese Medicine Compound Library

588 compounds
A unique collection of 588 compounds derived from traditional Chinese medicines (TCMs) for promoting blood circulation and removing blood stasis.
TargetMol